Tumor markers are substances that are produced by cancer or by other cells of the body in response to cancer or certain benign (noncancerous) conditions. Most tumor markers are made by normal cells
The Optical Q™ PSA diagnostic test is a proprietary point-of-care (POCT) fluorescence immunoassay (FIA) designed for prompt and accurate in-vitro quantitative measurement of PSA. Prostate specific
regu-latory T cells, follicular T helper cells, memory CD4+ T cells, and CD8+ T cells, but it is not expressed on B cells or naive CD4+ T cells. TIGIT may...paraffin-embedded tissue specimen. It has been validated for the identification of TIGIT positive T-cells infiltrating human tumors in order to allow the detection...of TIGIT in the tumor microenvironment under pathological conditions. TIGIT (T-cell immunoreceptor with Ig and ITIM domains) is a member of the poliovirus...receptor (PVR) family and acts as an im-mune checkpoint protein expressed on subsets of T lymphocytes. The expression of TIGIT has been reported on NK cells,...microenvironment through its impact on other immune cells, for example, by binding to CD155 on the surface of dendritic cells or by manipulating NK cell activity....Clone TG1 is the first monoclonal antibody detecting TIGIT (T cell immunoreceptor with Ig and ITIM domains) in routine formalin-fixed...be upregulated on naive CD4+ T cells upon activation. TIGIT has been shown to be upregulated on T cells in multiple cancer models. The ligands CD155 and CD112...are also highly expressed on dendritic cells and macrophages in several types of cancer. Additionally, TIGIT expression is highly correlated...with the expression of other coinhibitory molecules, including PD-1. In addition to directly inhibiting cytotoxic T-cell activity, TIGIT can foster an immunosuppressive...for clinical research and potential therapeutic interventions specifically targeting the TIGIT-related tumor immunology checkpoint.
applications: Separation of plasma from whole blood Blood cell separation (mononuclear cells, circulating tumor cells, white blood cell subpopulations) Gentle...The AcouWash is a benchtop research instrument for label-free separation of target cells from a variety of samples. In the AcouWash, acoustic forces...are used to separate different cells and microparticles from each other based on differences in their physical properties. Gentle ultrasound is used to move...target cells from one flow path to another as the sample travels through a microchannel. With its gentle automated processing, AcouWash is excellent...for performing sensitive separations and handling fragile cells without any loss in viability. The result is high-quality samples with minimal variation. AcouWash...cell wash Separation of bacteria and platelets from blood
CPB-1200 Celief is Hyperthermia Device used to cure cancer and the treatment method for necrosis of cancerous tissue by heating tumor cells using...only cancer cells to necrosis or self-death. It is a treatment that slowly destroys cancer cells by inhibiting the proliferation of cancer cells by blocking...the supply of oxygen to the cancer cells while increasing the metabolic rate of cancer cells by applying heat to the cancer tissue. Also, it is adopted...high-frequency waves. High-frequency Hyperthermia cancer treatment selectively applies high-temperature heat of 42 to 43° celsius to the tumor tissue, causing
Antinuclear antibodies (ANA) are a collective term for all autoantibodies that recognize conserved (i.e. present in all cells) nuclear antigens....In a narrower sense, ANA are those autoantibodies that cause nuclear staining in indirect immunofluorescence on tissue sections or tumor cell monolayers (e.g.,...HEp-2 cells). [Conrad K. et al., 2010, Lengerich: Pabst Science Publishers]. ANA are typical findings in inflammatory rheumatic diseases (systemic...the cell nuclei of typically HEp-2 cells are stained by means of IIFT and, in the case of a positive result, are usually characterized in more detail...connective tissue diseases, also called collagenoses), but can also be found in varying frequency in almost all other autoimmune diseases as well as tumors.
margins of the cancerous tissues of patients during breast cancer surgery. The system lively determines the H2O2 released from cancer or atypical cells,...cancer cells in the breast causes re-surgeries and inevitable post-surgical treatments, which will have several side effects. Frozen pathology of tumor...reported revisions)). The distinctive ability of CDP to detect cancer cells in the internal margins (after tumor dissection) during surgery has been obtained...This is a real-time system which has been developed to diagnose the presence of pre-neoplastic/neoplastic cells in either internal or external...the cancerous cells in the internal margins (cavity-side margin) within a few millimeters in 40 seconds, using a needle sensor. This system has a clinical
of encapsulating Stem Cells, Biologics, and other conventional drugs, and injectible to accomplish goal of minimally invasive surgery. Electromagnetic Actuator,...medical needs. Using Magnectio, all patients could benefit higher tissue regeneration efficacy through enhancing grafting rate of cell delivery over 80%...compared to 2% that of injection By reducing one-time dose of stem cell therapeutics, Magnectio could reduce side effect of stem cell theratputics...method; it could lead cell regeneration therapeutics industry...such as benign tumor, and also reduce cost of therapeutics. Magnectio could enable highly effective tissue regeneration therapeutics by minimally surgical
and in the study of pituitary disease. It reacts with ACTH-producing cells (corticotrophs). It also may react with other tumors (e.g. some small cell carcinomas...and Rat. Expected to show a broad species reactivity. Positive Control: Normal pituitary gland or pituitary tumor. Specificity: This antibody is specific...to Synacthen (aa 1-24 of ACTH); this antibody does not react with CLIP (aa 17-39 of ACTH). Anti-ACTH is a useful marker in classification of pituitary tumors
for necrosis of cancerous tissue by heating tumor cells using high-frequency waves. Previously there have been many types of Hyperthermia devices. But this time,
is a cancer treatment that induces cancer cell death by heat generated in tumor tissue exposed to near-infrared light. FluoGuide's FG001 has the potential...to act as a near-infrared light absorbent to facilitate efficient and cancer cell targeted heat destruction. Photothermal therapy is an extension...to an excitation state where it releases energy in the form of heat. Under optimal conditions, the generated heat will kill cancer cells while sparing normal tissue.
lesions or tumors can be removed. Furthermore, inflammations can be treated so that they do not give rise to cancer cells....of the intestine, the polyps. Not every polyp develops into a malignant tumor, but such growths should be removed as a precaution when they are discovered. Polyps can
be expressed very well in bacterial cells. Each E. coli protein production project involves cDNA design and efficient codon optimization for expression...in bacterial cells....peptides and proteins without post-translational modifications such as antigens, bacterial proteins, hormones, prohormones, tumor markers or cytokines can
of tumors including anaplastic large cell lymphomas, neuroblastoma, and non-small cell lung cancer. The chromosomal rearrangements are the most common genetic
(FFPE) non-small cell lung cancer (NSCLC), colorectal cancer (CRC) and gastrointestinal stromal tumor (GIST) tumor tissues
burden (TMB) mutation signatures HLA types T-cell receptor (TCR) clonality All findings are annotated with a curated knowledge database of approved...in all melanoma-relevant genes melanoma-relevant gene rearrangements copy number variants (CNV) in a genome-wide manner and chromosomal aneuploidies total tumor mutational...in an automatically generated customized report, providing a precise diagnosis of the tumor as well as therapy decision support.
PSA has been detected in various tissues of the male urogenital system but only prostate glandular cells and endothelial cells secrete it. The PSA...for the diagnosis of early prostate cancer. Many studies have confirmed that the presence of PSA is the most useful and meaningful tumor marker known for prostate
in cell-free circulating DNA (cfDNA) levels. To ensure effective patient care, it is necessary for doctors to know early on whether a patient is responding...A simple blood test to monitor tumor response & progression after treatment. The DiaCarta RadTox™ Test is intended to offer an early...assessment of patient response to treatment. It is a simple blood test to monitor tumor response & progression after treatment by monitoring changes
thyroiditis, early Hashimoto’s disease, iodine-induced hyperthyroidism, germ cell tumors, and trophoblastic disease. Decreased levels of T4 indicate