For long Molecular Diagnostics has been the domain of large central laboratories requiring patients and samples to travel long distances for a test to be conducted. These pose several logistic and technical challenges leading to increased costs and delayed results. The veracity of such results and impact of such intervention in treatment outcome have always been questionable. This has led to a poor uptake of such reliable and cutting edge technologies that have potential to save millions of lives, mitigate sufferings and reduce disease burden and anti-microbial resistance. The lack of timely access to good diagnostics has been the bane of health care needs, particularly of the Low and Middle Income Countries.
The Truelab Real Time quantitative micro PCR system from Molbio Diagnostics brings PCR technology right to the point-of-care, at all laboratory and non-laboratory settings, primary centres, in the field, near patient, essentially at all levels of healthcare thereby decentralizing and democratising access to molecular diagnostics. With a large and growing menu of assays for infectious diseases, this rapid, portable technology enables early and accurate diagnosis and initiation of correct treatment right at the first point of contact. The platform is infrastructure independent and provides complete end to end solution for disease diagnosis. With proven ability to work even at Primary Health Centres and with wireless data transfer capability, this game changing technology brings in a paradigm shift to the global fight in control and management of devastating infectious diseases.
The system works on disease specific Truenat microchips for conducting a real time PCR. The sample preparation (extraction and purification) is done on a fully automated, cartridge based Trueprep AUTO sample prep device.
We from Molbio are proud to bring in this revolutionary technology and commit ourselves to continuous efforts towards improving the health and well being of the global population.
Key Impact of Truenat
Molecular Diagnostics is the state of the art in Diagnosis of infectious diseases. It works on the principle of DNA amplification, hence provides the ability to diagnose disease early in infection because of its excellent sensitivity and specificity. This technique has thus far, been limited to centralized laboratories due to dependency on complex and expensive infrastructure, highly skilled manpower, special storage conditions and need for batch testing. This results in high turn round time and poses major logistics challenges such as sample degradation, contamination, delays, etc.
Molbio now offers a 'global first' platform that can perform Molecular Diagnostics for infectious diseases at the point-of-care - Truelab Real Time Quantitative micro PCR System. This compact battery-operated system has single testing capability and provides sample to result within 1 hour. Hence, it enables same day reporting and initiation of evidence-based treatment for the patient. It also has real-time data transfer capability (through SMS/E-mail/data push) for immediate reporting of results in emergency cases.
Doctors and patients benefit from this technology by having a definitive diagnosis, early in the infection cycle, at the point of first contact so appropriate treatment can be initiated. Early and timely intervention also helps in preventing spread of the disease.
ICMR, after extensive validations has found Truenat to be a more sensitive and specific test and hence recommended it as a replacement to smear microscopy for diagnosis of TB and Rifampicin resistance under the RNTCP algorithm. Ministry of Health has now initiated roll-out of the test across India, with Andhra Pradesh being the first state to use Truenat as a frontline tool for TB detection at Primary Health Centre level. With this intervention, the state is seeing a substantial increase in case detection.