Lich, November, 11th 2020 – In order to be able to clearly type disease associations in an even more time- and cost-efficient way, BAG Diagnostics is developing a new product line: With the kits of the FastQ® series, celiac disease, M. Bechterew et al. and Haemochromatosis can be determined quickly and reliably by real-time PCR. It does not have any relevance whether the raw material is present as DNA or blood sample. Thanks to the Blood Booster Reagent developed especially for FastQ®, blood samples can even be easily diluted and pipetted directly. FastQ® B27 direct for typing of M. Bechterew et al. - directly from blood as starting material - is already available. For the typing of M. Bechterew et al. and Celiac disease from DNA the test kits are also already available.
It is no longer conceivable to imagine human genetics without real-time PCR for the typing of disease associations. The new FastQ®-Line from BAG Diagnostics combines the advantages of real-time technology with high-performance multiplex PCR. Within a single PCR approach, genes associated with celiac disease, M. Bechterew et al. and Haemochromatosis can be detected from DNA as well as from blood samples as starting material.
The PCR programme used ensures an optimized workflow: once set up, it can be used for all FastQ® kits. The specificity of the reaction is defined both by the primer sequences and the probe sequence. This increases the resolution and reduces false-positive reactions to a minimum. Blood Booster – pipette directly from blood
The FastQ® direct kits eliminate the need for time and cost intensive DNA isolation. Thanks to the specially developed Blood Booster Reagent, the advanced real-time assays allow PCR amplification directly from diluted blood samples. The stabilising effect of the reagent allows absolutely safe and reproducible results even with very fresh and difficult blood samples (e.g. with a high EDTA concentration). Minimised Hands-On-Time
Depending on the starting material - DNA or blood samples - results are available after 60 or 90 minutes. Ready-to-use standard reagents and optimised multiplexing ensure a high data throughput. For reliable results, an internal amplification control is included in every PCR approach. Optimised workflow
Real-time PCR works without gels and guarantees a simple workflow and safe handling. Cost-intensive disposal of environmentally harmful toxic residues is not necessary. Working with closed reaction vessels after amplification also prevents contamination in the post-PCR area.
Already available test kits of the FastQ®-productline: Amplification from DNA:
M. Bechterew et al.
FastQ® CDAmplification from whole blood:
M. Bechterew et al.
FastQ® B*27 direct
The kits FastQ® HFE and FastQ® HFE direct for typing for Haemochromatosis and the FastQ® direct-variant for typing for Celiac disease will be available shortly.
Detailed information: www.bag-diagnostics.com/en/humangenetic-real-time-pcr-typing.html This text has 2,985 characters including spaces. Further information and a wide variety of images are available in electronic form at firstname.lastname@example.org. A specimen copy to the agency is requested.