Medical Products Research srl

Medical Products Research Srl is an Italian manufacturer of medical and electromedical devices for both hospital and home-care market.

Founded in 2005, its head office is in Legnano (Italy) where the devices are entirely designed and developed, to guarantee the “Made in Italy” quality standard.

MPR focuses on respiratory diseases and in particular on airways clearance.

The aim of the company is the continuous research for innovative solutions to develop therapeutic treatments as less-invasive as possible, respecting the physiologic parameters involved in the process of breathing and airways clearance, limiting the contraindications often related to traditional therapies and, as consequence, improving comfort, adherence and effectiveness.

MPR devices are studied to match needs of adult and paediatric, collaborative and non-collaborative patients.

The company owns 2 patents, both recognised at national and international level:

TPEP® (TEMPORARY POSITIVE EXPIRATORY PRESSURE) technology
Patented in 2005, the technology TPEP® (Temporary Positive Expiratory Pressure) aids patients in the removal of bronchial secretions, applying a minimum temporary positive pressure in exhalation needed to counteract the airways collapse without penalising the expiratory flow. This technology, completely non-invasive, has proven to be highly effective in patients suffering from respiratory dysfunction and hypersecretion. Over the years, a number of clinical research studies have demonstrated the effectiveness of the system. Today, TPEP® represents a valid support for respiratory rehabilitation and it has proved to be a good solution for many patients, respecting the organ that is the cause of their problems.

EFA® (EXPIRATORY FLOW ACCELERATOR) technology
In 2009 MPR developed a second patented technology called EFA® (Expiratory Flow Accelerator). This innovative technology accelerates the expiratory flow, promoting deep drainage and secretions removal in patients with ineffective cough, without applying any pressure in the airways. The secretions safely reach the upper airways where the patient can expel or ingest them in a physiological way through the mechanism of the mucociliary system.

TPEP® & EFA® technologies are available in stand-alone devices or integrated in multifunctional equipments specifically studied to help health operators to customize the treatment on each single patient.

KALOS cough machine responds to the growing awareness that patients with neuromuscular disorders and problems in managing bronchial secretions need customized treatments based on different techniques.

Integrated with the cough assist function, KALOS is also equipped with EFA® (Expiratory Flow Accelerator) technology for a deep and gentle clearance of the airways, as well as the possibility to perform lung expansion manoeuvres with the Continuous Pressure mode, and the ability to check the effectiveness of the patient’s cough through a digital peak cough flow indicator.

According to expert projections, it is estimated that 30% of patients affected by COVID-19 could have permanent lung damage and very disabling alterations in respiratory function.
In this phase it is essential to intervene with targeted and personalized strategies to restore the best functional conditions and prevent secondary lung damage.
The suggestions of the experts are reported in “Italian suggestions for pulmonary rehabilitation in COVID-19 patients recovering from acute respiratory failure: results of a Delphi process" recently published in the Monaldi Archives for Chest Disease magazine.

TPEP®4 provides the best technology to respond to the suggestions of the experts.
The therapeutic options included, with the possibility of integrating and modulating the different strategies, allow a flexible, personalized and safe treatment. The inspiratory and / or expiratory flow-dependent resistance with adjustable pressure target, the comfortable visual and auditory feedback, allow to guide and assist the patient in the correct execution of what is prescribed by the clinician, even when the therapy must continue independently or remotely .

The administering, by FREE FLOW device, of heated and humidified high-flow air, possibly enriched with oxygen, allows comfortable and controlled oxygen therapy and adequate ventilatory support, as well as ensuring the fluidification of bronchial secretions.

The humidification therapy is complementary to the incorporated EFA® technology, that supports muco-ciliary clearance by facilitating the mobilization and removal of secretions in a non-invasive way.

Through a compact and handy design, built-in battery and convenient foldaway handle, FLOW KLEANER ensures an optimal clearance throughout the entire bronchial tree for adult and pediatric patients.

Beside the innovative suction system, EFA® technology allows a deep, safe and comfortable airways clearance, purely by means of expiratory flow acceleration.

EFA® technology decreases the need for intervention with deep aspirations, that often cause discomfort and sometimes are even harmful for the patients.

FREE ASPIRE ADVANCED is a medical device for non-invasive removal of tracheo-bronchial secretions, designed for adult and paediatric patients with reduced or absent cough capacity.

It employs EFA® (Expiratory Flow Accelerator) patented technology.
Through an acceleration of the expiratory flow, the tracheo-bronchial secretions reach the upper airways, in complete safety and without any contraindications, so allowing the patient to expel them or ingest them if unable to eject them spontaneously.
Therapy with FREE ASPIRE ADVANCED is comfortable and respects the patient’s natural breathing pattern. Patients feel no unpleasant sensation during the therapy.

SUCTION FREE is a medical device for the management of tracheobronchial secretions in hospitalized patients. It is a user-friendly system employing EFA® developed for adult and paediatric, even non-cooperative, patients with reduced or absent cough capacity.

SUCTION FREE is generally employed in the following hospital wards:
• ICU
• Geriatrics
• Oncology
• Stroke Unit
• Neurology
• Heart Surgery
• Thoracic Surgery
• Pulmonology
• ENT
• Neonatology
• Paediatrics