Zivak Inc. of Delray Beach, FL at MEDICA 2019 in Düsseldorf -- MEDICA - World Forum for Medicine
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Zivak Inc.

1395 NW 17th Ave. #104, 33445 Delray Beach, FL
USA
Telephone +1 888 9494825117
Fax +1 561 4040330
info@zivak.com

Hall map

MEDICA 2019 hall map (Hall 1): stand F04

Fairground map

MEDICA 2019 fairground map: Hall 1

Our range of products

Product categories

  • 02  Laboratory Technology
  • 02.01  Analyser systems / equipment

Our products

Product category: Analyser systems / equipment

FX-2000

DESIGN YOUR OWN FULLY AUTOMATED UHPLC SYSTEM

Zivak Technologies has launched a new UHPLC system!

FX-2000 is a fully automated UHPLC system with optional sample preparation and detection modules. This system aims at:
 Fully automatizing your chromatography analysis
 Eliminating user errors caused by manual sample preparation
 Addressing low throughput problem in chromatography analysis
 Lowering the cost of analysis
 Turning your mass spectrometry device into a convenient tool, a real walk away analyser for routine analysis.

FX-2000 allows you to compose your own fully automated UHPLC system tailored to the needs of your laboratory. Zivak Technologies offers a wide range of sample preparation module, UHPLC pump, degasser and detector options to choose from so you can design what is best suited to your analysis. The optional modules do not have to be placed in certain spots, you arrange the interior design of the instrument at your convenience.

FX-2000 can be connected to any brand or model of mass spectrometry device and turns your mass spectrometer into a real walk away analyser.

All sample preparation steps are carried out by fully automated modules, eliminating user errors caused by manual sample preparation. As all Zivak analysers, FX-2000 injects from closed cap primary sample collection tubes, you never have to worry about contamination. Thanks to its Liquid Level Detection capability, sample volume is no longer an issue. You do not have to use special vials for this system. FX-2000 works with standard sample collection tubes.

FX-2000 will enable your mass spectrometer to become a convenient tool for routine analysis by lowering the cost of analysis, delivering solution to low throughput problem in chromatography analysis and eliminating user errors with its fully automated sample preparation modules.

With FX-2000 Flexible UHPLC System, all you have to do is to place your primary sample collection tubes and get results. You will not be bothered by opening sample tube caps or sample transferring.

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Product category: Analyser systems / equipment

Vitamin D2/D3 UHPLC Analyzer

World First Walk Away Vitamin D2/D3 UHPLC Analyzer 

Why we analyze 25-OH Vitamin D2 and D3 separately?

Circulating 25-hydroxyvitamin D (25-OH-D) is widely recognized as the best indicator of vitamin D status. In blood circulation the two major vitamin D metabolites are 25-OH Vitamin D3 and 25-OH Vitamin D2.  25-OH-D3 is mainly derived from vitamin D3 produced by sunlight in the skin, while 25-OH-D2 is derived from plants in the diet. There are currently two main types of methods used routinely for measuring 25-OH-D: methods based on chromatographic separation followed by non-immunological direct detection and competitive immunoassays. Most immunoassays depend on an antibody that can detect both 25-OH Vitamin D2 and 25-OH Vitamin D3 together and gives total results. But the proportion of 25-OHD2 detection is variable.

Two non-immunological methods for direct detection are currently available: high pressure liquid chromatography (HPLC) and liquid chromatography-tandem mass spectrometry (LC-MS/ MS). Chromatographic methods are able to measure 25-OH-D2 and 25-OH-D3 independently with excellent accuracy and sensitivity.

On the other hand, there is many scientific studies and papers showing inaccuracy measuring total Vitamin D with commercial immunoassays without separating and measuring Vitamin D2 and Vitamin D3 metabolites individually. It is recommended that any 25-OH-D assay in clinical laboratories should measure both 25-OH-D2 and 25-OH-D3 equally in order to report a total 25-OH-D value. The evaluated immunoassays measure total 25-OH-D (both 25-OH-D3 and 25-OH-D2), but the cross-reaction with 25-OH-D2 and 25-OH-D3 differs from 52 to 100% in different methods.

Walk Away Analyzer

HPLC and LC-MS/MS methods are accepted as Gold Method for separate analysis of 25-OH metabolites of Vitamin D. Usage of these chromatographic methods are being increased significantly on clinical laboratories recent years. The major disadvantage is the time-consuming and laborious extraction procedure that limits the number of samples that can be processed per day.

Many of these laboratories cannot use their chromatography systems effectively due to these systems required qualified staff, complex sample preparation steps, high kit prices/ operation costs and no availability of walk away systems.

VD-200 enables to analyze Vitamin D2/D3 samples fully automated – without any human intervention- from primer sample tube. By the way, the low throughput in chromatography analysis will not be a problem for the laboratories.

Cost Effective

Due to large number of Vitamin D2/D3 samples, many laboratories cannot run all other LC-MS/MS specific analysis on their LC-MS/MS systems effectively. VD-200 is especially designed the for the laboratories to provide them a cost- effective solution with a fully automated system and make customer’s expensive LC-MS/MS systems free for specific tests which have to be run on LC-MS/MS system.

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Product category: Analyser systems / equipment

System for LC-MS/MS analysis kits

Full automated sample preparation AND injection system for LC-MS/MS analysis kits

Zivak Technologies has developed state of the art sample preparation system for Mass Spectrometry devices. The system can be connected to different brand of MS/MS systems like Shimadzu, Agilent, Waters, Thermo and ABI Sciex which supported TTL connection protocol.

Zivak MULTITASKER  is the automated UHPLC system with built-in sample preparation which enables to automate major LC-MS/MS analyses in the clinical laboratories such as Vitamin D2/D3, Amino acids, Organic acids, Immunosuppressant Drugs without any human intervention- from primer sample collection tube. Many different LC-MS/MS methods can be automated with the system. 

This eliminates the errors from manual sample preparation steps. With MULTITASKER, the low throughput in chromatography analysis will not be a problem for the laboratories any more. Zivak MULTITASKER system can inject from closed cap sample collection tubes. This eliminates the contamination risk from the opening tubes for the technician. The volume of samples is not an issue for the system since Liquid Level Sensing capability from closed cap sample collection tube.

Zivak MULTITASKER system can invert the whole blood sample tubes for homogenisation before the sample preparation if needed. The system automatically generates sample sequence by reading barcode from primary sample collection tube which barcoded by hospital LIS system.  Due to rotational barcode reading which followed by automated sample preparation, the system is independent from placing order or position of barcode of the samples in sample tray. 

Zivak Multitasker was especially designed for routine testing for the clinical labs. Zivak Multitasker enables to make Vitamin D2/D3, Amino acids, Organic acids, Immunosuppressant Drugs and the other major LC-MS/MS analyses fully automated – without any human intervention- from primer sample tube after the technician place the samples on the sample tray.

The Multitasker system automatically generates sample sequence by reading barcode from primary sample tube which barcoded by Hospital LIS system.  PLACE YOUR SAMPLES AS YOU GET without align the barcodes. 

Due to rotational barcode reading which followed by automated sample preparation, the system is independent from placing order or position of barcode of the samples in sample tray. Zivak MULTITASKER system can invert the whole blood sample tubes for homogenisation before the sample preparation if needed. Also this system fulfills the requriements for the positive sample identification of CE-IVD regulations.

The sequence list directly generated from the barcodes of the samples. There is no possible sample mismatch from the transfer of the samples from primary sample tube to standart chromatograpy vials or well plates. Therefore, there is no possibility to mismatch of the sample identity and results which directly transferred to the LIS system of the laboratory by the AutoMass Turbo V6 Software.  

Automass Turbo V6 Chromatography software is the new version of Automass Chromatography software which is developed for running with any type of LC-MS/MS instrument. Besides the main chromatographic features of Zivak Automass software, new version of the software includes LC-MS/MS data processing and custom reporting. With it’s easy, fast and user-friendly interface it improve the performance of instruments, save time and reduce laboratory costs.

User-friendly graphical interface for easy interaction
TTL connection with any LC-MS/MS instrument of following vendors : Agilent, SCIEX, Shimadzu, Waters, Zivak Tandem Gold
Single sample list while working with LC-MS/MS instrument (Mass Spectrometer software works single run)
Fast, automated data processing and automatic peak detection
Allows user to create, edit and print custom designed reports
Automatic LIS transfer of processed results

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About us

Company details

Zivak Technologies is an international special company providing ready to use LC-MS/MS and HPLC analysis kits in the clinical diagnostic field. Zivak Technologies supplies also its own fully automated sample preparation and injection system which enables laboratories around the globe to make efficient use if their LC-MS/MS instruments as well as HPLC instruments in a fast, accurate and cost efficient way.

Sales and marketing activities are carried out in more than 70 countries, either directly by the Headquarter or via distributors.

• Automated UHPLC system for MS/MS and walk away HPLC systems dedicated clinical analysis
• HPLC and LC-MS/MS analysis kits
• Consumables

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