Product category: Analyser appliances, Pipetting devices for microtiter plates, Point of care - testing systems
Microarrayer Nano-Plotter NP2.1
The Nano-Plotter is a non-contact micropipetting system for the volume range from 60 Picolitre. Main applications are printing of microarrays and manufacturing of array based diagnostics (multi parameter diagnostics). Small aliquots of diverse biomolecules will be tethered to solid surfaces, e.g. glass slides or well plates with 96 wells. The Nano-Plotter is available in two sizes, with one up to sixteen piezoelectric pipetting tips in any combination and many accessories like fiducial recognition camera.
This instrument prints melt biopolymers as well as bioinks at room temperature, enriched with living cells if desired. Fields of application are regenerative medicine, production of scaffold structure for cell based screening, finishing of metal implants and others. Generally the instrument prints most bioresorbable polymers. BS3.2 is available with pneumatic extrusion as well as with mechanical displacement dosage and high-voltage extrusion (MES).
Product category: Analyser appliances, DNA diagnosis kits, Lab-on-a-chip, Point of care - testing systems
BioSyntheSizer BSyS 3.1
This pipetting machine does much more than pipetting: Automatic vial- and tube handling, powder pipetting, multi-lumen pipetting (E.g. azeothropic drying), application of pressure-/ temperature profiles in a reactor vessel end others. The vial racks connect to purification columns if necessary.
The instrument is kind of a tool kit always configured to a particular application. Customers already successfully synthesized tracer chemicals for nuclear medicine as well as hydrogels for regenerative medicine.
µCP 4.1 is a compact benchtop instrument for two applications:
Microcontact printing of specific substances (E.g. proteins) onto solid surfaces: The lateral resolution can go below one Micrometer. "Patterned" surfaces may affect differentiation of stem cells. Up to four stamps with different patterns can print different substances on one target.
Nanoimprint Lithography (NIL) realizes 3D structures in soft polymers, e.g. photoresist. It allows the cost effective preparation of microfluidic devices.
Both methods utilize disposable stamps which can be done at the customer lab with the included casting station.
CeCuLab is based on Multi-Organ-Chips (MOC) with embedded closed but transparent cavities (e.g. well plate inserts) for cell/ tissue growing. The MOC cavities are part of an onboard microfluidic circuit with pumps and valves for supply and removal of reagents, nutrition samples and gas and can be accomplished by integrated sensors. The MOCs host cells, either in suspension or embedded into small Alginate scaffolds (micro organoids). For automatic handling the MOCs are kept at microscope slide format.
An array of MOCs fits onto a dedicated GeSiM robot with multiple tool head for liquid handling from Nanolitre to Microlitre range, 3D printing by extrusion, (UV-) light excitation, camera, temperature control, ELISA-detectors and others.
A prototype of the robot will be shown at our booth at Medica.