2810 7th Street, 94710 Berkeley, CA
United States of America

Telephone +1 484 713-2100
Fax +1 484 713-2900


Hall map

COMPAMED 2016 hall map (Hall 8a): stand K28

Fairground map

COMPAMED 2016 fairground map: Hall 8a

Our range of products

Product categories

  • 09  Raw materials and adhesives
  • 09.03  Coatings, biocompatible

Coatings, biocompatible

  • 09  Raw materials and adhesives
  • 09.06  Coatings, lubricative

Coatings, lubricative

  • 09  Raw materials and adhesives
  • 09.08  Biodegradable polymers

Biodegradable polymers

  • 09  Raw materials and adhesives
  • 09.10  Copolymers
  • 09  Raw materials and adhesives
  • 09.11  Dental materials

Dental materials

  • 09  Raw materials and adhesives
  • 09.21  Ceramics
  • 09  Raw materials and adhesives
  • 09.22  Adhesives, adhesive tapes

Adhesives, adhesive tapes

  • 09  Raw materials and adhesives
  • 09.33  Polycarbonate


  • 09  Raw materials and adhesives
  • 09.35  Polyethylene PE

Polyethylene PE

  • 09  Raw materials and adhesives
  • 09.37  Polyurethane PU

Polyurethane PU

  • 09  Raw materials and adhesives
  • 09.45  Urethanes


Our products

Product category: Copolymers

Collagen technology

Collagen products used in medical devices
DSM produces animal derived collagen for use in a wide range of medical devices. Collagen is a natural protein and the predominant biomolecule found in blood vessels, dermis, tendons, ligaments, cartilage, and the organic phase of bone.
Biocompatible implants
Because of its many appealing characteristics, collagen has a long history of use in medical devices ranging from hemostats and surgical meshes to bone void fillers. The material is ideal because, when purified properly, it is biocompatible, can be provided in a variety of shapes and sizes, and acts as a temporary scaffold for tissue regeneration.

Collagen processing technology
DSM produces medical devices from various collagen formulations. These materials are manufactured from purified collagen extracts derived from bovine dermis, which is a source of primarily Type I Collagen. The difference between DSM's formulations is the degree to which the collagen fibers are dissociated. Collagen fibers are ordered bundles of collagen fibrils, which, in turn, are ordered as bundles of collagen molecules (tropocollagen). With our purified collagen processing technology we have the ability to process collagen in fiber, fibril and soluble collagen forms. From raw materials to devices, our slurry and solution processing allows us to make products with custom-tailored properties for your application.

Collagen configurations
Our collagen processing allows us to provide products in many different forms including sheets, putties, injectables, gels, three dimensional shapes, coatings, fibers or powders to create resorbable medical devices. With these novel processing methods, we can produce custom architectures to meet the specific performance characteristics of end-use products.

Collagen blending and compounding
To further enhance the customization of your product, we have the ability to blend additives into the collagen forms. We have experience compounding many different active ingredients including:

Beta-tricalcium phosphate
Anorganic bone
Calcium sulfate
Bioactive glass
Synthetic polymers
Hylauronic acid
Control of mechanical properties
In medical applications where higher strength or longer in-vivo persistence is required, DSM’s proprietary methods for orienting the fibers in the collagen impart greater strength. We can alter the physical and chemical properties by adding chemical or non-chemical crosslinking. We can optimize these methods of formulation to provide the best material properties for your application.

Manufacturing controls
In addition to taking measures to ensure that the starting materials are disease free, DSM has controls in place to ensure that the materials remain safe throughout various manufacturing processes. Our manufacturing facility is ISO 13485 certified and our collagen is processed in certified ISO Class 8 cleanrooms. With routine audits and testing, we ensure the material always meets government and customer specifications.

Potential end-use applications
DSM’s collagen configurations have the potential to be used in a variety of clinical applications, ranging from bone void fillers and cartilage repair devices, wound dressings and hemostatic agents, to nerve regeneration conduits and tissue augmentation supports.

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Product category: Ceramics

Bioceramics technology

Medical ceramics for bone graft substitute in orthopedic, dental and sports medicine applications
DSM specializes in the design, development, commercialization and manufacturing of bioceramic medical devices. Bioceramics have a long history of being used as a bone graft substitute in orthopedic, dental and sports medicine applications. When properly designed, bioceramics provide an ideal synthetic osteoconductive scaffold for bone regeneration.  

Bioceramic Development Lab
DSM’s fully equipped state of the art ceramic development lab and testing facility can facilitate your development efforts. DSM’s knowledge and technical capabilities allow for bioceramics to be designed and developed to best meet our partners’ medical device needs and can be supplied in a number of forms to provide optimal handling characteristics for the end application.

Design and manufacturing of ceramic medical devices
Our diverse design and manufacturing capabilities allow for bioceramic medical devices to be provided as powders, granules, porous shapes, settable pastes, settable putties and anorganic bone. By collaborating with our knowledgeable development and commercialization teams, we can guide and assist in the co-development or customization of your bioceramic product.
Calcium Phosphates
To further enhance customization, we have the ability to manufacture various calcium phosphate powders used in medical devices that include:

α-TCP (tricalcium phosphate)
β-TCP (tricalcium phosphate)
MCPM (monocalcium phosphate monohydrate)
Our state of the art high temperature powder processes provide the flexibility to create high purity, bi-phasic and tri-phasic ceramic products. In addition, our expertise in conditioning powders provides the necessary control to target the powders’ physical attributes needed for the desired reaction kinetics in the final formulation.

Porous ceramic medical devices
DSM also has the capability to create porous ceramic medical devices. Our cutting edge porous ceramic technology creates interconnected micro and macro porous structures that are ideal for cell migration.

Medical ceramic composites
In addition to our diverse ceramic capabilities, we have the ability to create ceramic composites from collagen and a number of resorbable polymers such as PLA, PGA and PCL. By combining our technical capabilities with your design, we can provide ceramic composites in a number of forms to address the challenges you face in achieving the optimal handling properties for your end application.

Collaboration synergies
DSM specializes in combining our bioceramic design, development, commercialization and manufacturing expertise with our partners’ vision and marketing capabilities to provide leading edge regenerative medicine solutions to the world. We are a full service one stop shop for medical device companies who desire the expertise and capabilities that DSM can provide throughout the entire life cycle of your product.

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Product category: Adhesives, adhesive tapes

Adhesive technology

Medical adhesive biomaterial in protective coatings and adhesive films
DSM adhesive technology was inspired by marine mussels and the remarkable substance they secrete to bond to underwater surfaces. Our scientists create synthetic mimetics of these proteins and use them to build adhesive polymers that can be tailored to fit a broad variety of indications.
Recognized adhesive technologies
Our innovations were recognized with a title article in the July 2007 issue of Nature and they were labeled "one of the top 100 scientific developments of 2007" by Discover Magazine.  Our collaborators have won numerous awards for research using marine mussel adhesive technologies.

Medical indications & partnership opportunities
DSM offers adhesives that may be applicable across a broad variety of medical indications; as standalone products or as adjuncts to other medical devices.  We engage corporate partners to develop products that meet the medical needs of many different surgical procedures.

The flexibility of our chemistry enables us to tailor performance characteristics of the material specifically for each application.

Delivery system for surgical adhesives
Our products are typically delivered as a hydrogel in situ or pre-coated onto an adjunctive medical device. The delivery system can also be tailored to the application for ease of surgical use and optimal distribution of the medical adhesive.

DSM polymers are “tuned” to meet our partners’ requirements. We can vary:

Set (cure) time
Degradation time
Swelling volume
Other characteristics
All of these can be changed without significantly impacting our superior burst, peel, and shear strength.

Protective antifouling coatings
Bacterial infections complicate the outcome of millions of medical procedures each year.  Catheters, orthopedic implants, and other devices can become the locus of infection when pathogenic bacteria form biofilms. DSM is developing anti-fouling coatings to prevent bacteria from attaching to surfaces, thereby disrupting the formation of biofilms and their harmful consequences.

Antifouling surfaces for medical devices
DSM couples a biocompatible surface anchoring group to an antifouling polymer, such as polyethylene glycol (PEG), to passively inhibit bacteria from adhering to the medical device.  Because bacteria cannot colonize on the device surface, they cannot create biofilms.

Benefits of antifouling coatings
Many medical device coatings attempt to reduce bacterial infection by releasing active biocides.  These biocides may not protect against new bacterial strains, and may actually promote the evolution of resistant strains.  Moreover, the biocides can prove toxic to surrounding tissues.

DSM is designing anti-fouling coatings aimed at preventing bacterial attachment and colonization on a device surface by any bacterial strain. Importantly, anti-fouling coatings may also reach the market with lower regulatory costs because they do not contain active biocides.

Performance of DSM antifouling coatings
In preliminary testing, the DSM anti-fouling coatings have reduced bacterial attachment by more than 99% over untreated titanium surfaces.

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Product category: Polyethylene PE

Biomedical Polyethylenes

Recent breakthroughs in medical textiles have enabled manufacturers to create various implantable devices ranging from innovative sutures to improved cardiovascular devices. As a leader in ultra-high molecular weight polyethylene (UHMWPE) fiber technology, DSM has played a significant role in developing new materials that help improve orthopedic and cardiovascular implants and procedures and return patients to active lifestyles.

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Product category: Polyurethane PU

Biomedical polyurethanes

There are an estimated six million people walking the earth today with implanted devices that contain key biomaterials from DSM. Our strength in biomaterials comes from a unique convergence of our expertise in strong, lightweight, flexible polymers and our knowledge of human cells and chemistry. The result is the development of biomaterials that are capable of interacting with the body safely, long term.
The overarching goal of DSM in the biomedical field is to provide materials to device manufacturers that enable their products to treat or prevent disease, save lives and preserve the quality of life for patients everywhere.

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About us

Company details

DSM is the leading medical device materials development and manufacturing partner in the world and has been working with medical device companies for over 25 years. By offering the broadest portfolio of biomaterials and process manufacturing in the industry, we help our partners increase the performance of each medical device. Our offering includes biomedical polyurethanes and polyethylenes, resorbable polymers, bioceramics, collagens, extracellular matrices, silicone hydrogels, coatings, and drug delivery platforms.

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