IGTP
Cardiac bioimplants for heart attack treatment
13/05/2024
A recent study highlights the safety and effectiveness of PeriCord bioimplants, derived from umbilical cord stem cells, for regenerating heart tissue post-myocardial infarction.
Mikaël M. Martino
Unveiling the role of sensory neurons in tissue repair
10/05/2024
Research from Monash and Osaka Universities highlights the key role sensory neurons play in tissue repair and regeneration, marking a significant advancement for regenerative medicine.
Michelle Bixby/Penn State
3D-printed skin technique potentially enhances reconstructive surgery
15/04/2024
A breakthrough in reconstructive surgery may be on the horizon, as researchers develop a 3D-printed skin that integrates hair follicle precursors, leveraging adipose tissue for more natural results.
TERM/UKW
The potential of nasal cartilage in knee joint treatment
05/04/2024
At the University Hospital Wuerzburg, a promising new treatment for knee joint defects involves the use of nasal cartilage, and it's edging closer to approval with significant EU funding. The new method is using autologous cartilage from the nasal septum, an approach that may seem as enchanting as the term "ENCANTO" implies.
NTU Singapore
Singapore: advancing 3D printing in healthcare with joint R&D lab
11/12/2023
Singapore General Hospital (SGH) patients are expected to benefit from healthcare innovations, such as customised medical devices and implants, under a collaboration with Nanyang Technological University, Singapore (NTU Singapore) to set up a Joint Research & Development Laboratory in additive manufacturing (AM), also known as 3D printing.
BellaSeno
Bioactive composite supports healing of broken bones
09/11/2023
A broken bone failing to heal represents an enormous burden for patients. Fraunhofer researchers have worked alongside partners to develop a composite material to be used in the treatment of such non-union cases. The resulting implant is designed to significantly improve treatment success rates and speed up the healing process.
Barth van Rossum, FMP
Microscopy and fluorescence show how synapses are formed
23/10/2023
How are synapses formed, those points of contact that allow the transmission of information from one neuron to the other? Working with an international team, researchers from the Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP) have now uncovered a crucial mechanism and elucidated the identity of the axonal transport vesicles that generates synapses.
Patrick Mansell/Penn State
High-speed bioprinting of bones, tracheas, organs
28/07/2023
Developing technology to quickly and efficiently bioprint human tissues at scale is the goal of a new project led by Penn State researchers. When fully developed, the technology will be the first to enable the fabrication of scalable, native tissues such as bones, tracheas and organs.
ellinnur
Biomaterials: toolbox for the development of bioadhesives
28/07/2023
The team of Prof. Dr. Thomas Scheibel, Chair of Biomaterials at the University of Bayreuth, has compiled a current overview of the state of research on protein-based bioadhesives.
Max-Planck-Institut für Polymerforschung
Jasmina Gačanin investigates living biomaterials
20/07/2023
Dr. Jasmina Gačanin, postdoctoral researcher at the Max Planck Institute for Polymer Research in the department of Prof. Dr. Tanja Weil, has been appointed as a “Peretti-Schmucker Fellow”.
yanadjana
Mobile cold plasma device: healing of chronic and acute wounds
13/07/2023
Skin diseases, chronic wounds or postoperative wounds often greatly restrict the quality of life for those affected. Improvement or healing of these conditions is usually time-consuming and costly. Terraplasma medical GmbH, a company of the Viromed Medical Group, uses cold plasma to pursue an effective approach to wound treatment.
HZDR/Sahneweiß
Magnetic stimulation: potential therapeutic approach for neurodegenerative diseases
19/06/2023
Motor neurons in healthy individuals send signals to the skeletal muscles. ALS, however, is currently an incurable, neurodegenerative disease in which motor neurons are severely damaged and can therefore no longer transmit these signals. An interdisciplinary team at HZDR has proven in cell experiments that magnetic fields can restore impaired motor neurons.
K. Selsam, Fraunhofer ISC
Wound healing: Fraunhofer Institutes develop bioresorbable membrane RENACER
13/06/2023
Treating large-area and internal wounds and promoting their often protracted healing remains a challenging task for medicine. Researchers at the Fraunhofer Institute for Silicate Research (ISC) and the Fraunhofer Institute for Toxicology and Experimental Medicine (ITEM) have developed the bioresorbable membrane RENACER®.
Fotogenia - Renate Trummer
Tissue Engineering: TU Graz revolutionises production of biocompatible microfibres
02/06/2023
Using a newly developed method for the efficient and cost-effective production of biocompatible microfibres, the production of autologous skin and organs can be significantly accelerated. Responsible for the development are Carole Planchette and her team from TU Graz.
Ella Marushchenko
Breaking through bacterial barriers in chronic treatment-resistant wounds
24/05/2023
Researchers in the UNC School of Medicine's Department of Microbiology and Immunology and the UNC-NC State Joint Department of Biomedical Engineering have developed a new strategy to improve drug-delivery into chronic wounds infections.
NTU Singapore
Why wavy wounds heal faster than straight wounds
19/05/2023
Wavy wounds heal faster than straight wounds because shapes influence cell movements, a team of researchers at Nanyang Technological University, Singapore (NTU Singapore) has found.
WFIRM
Bioprinting research makes history when it soars to the ISS
17/05/2023
The Wake Forest Institute for Regenerative Medicine (WFIRM) will make history this month when the first bioprinted solid tissue constructs soar to the International Space Station (ISS) on board the next all private astronaut mission by commercial space leader Axiom Space.
UBT / Chr. Wißler.
Regenerative medicine: cell-specific properties of novel spider silk materials
12/05/2023
Materials made of spider silk can be specifically modified or processed in such a way that living cells of a certain type adhere to them, grow and proliferate. This has been discovered by researchers at the University of Bayreuth under the direction of Prof. Dr. Thomas Scheibel.
Universität des Saarlandes/Oliver Dietze
Exploring the molecular mechanisms of ageing
09/05/2023
A team led by bioinformatics experts Andreas Keller and Fabian Kern from Saarland University together with researchers at Stanford University have gained new insights into manifestations of ageing at the molecular level.
TUD/Magdalena Gonciarz
A sweet solution to a cracking problem: new bio-inspired molecules to promote bone regeneration
08/05/2023
An interdisciplinary team of scientists in Dresden developed novel bio-inspired sugar-based molecules that show potential to improve bone regeneration.
UCD Research and Innovation
Novel combination of therapies may provide new treatment option for bone cancer
03/05/2023
New research has identified a potential therapeutic target and developed a unique delivery system to treat osteosarcoma, a bone cancer that primarily affects children and adolescents.
Giuseppe Intini
New approach helps skull bones mend themselves
24/04/2023
In a new study published in Proceedings of the National Academy of Sciences, University of Pittsburgh researchers developed a novel approach that promoted bone regeneration in mice without implantation of bone tissue or biomaterials.
Science Brush | Hassan A. Tahini
How electricity can heal wounds three times as fast
21/04/2023
Using electric stimulation, researchers in a project at Chalmers University of Technology, Sweden, and the University of Freiburg, Germany, have developed a method that speeds up the healing process, making wounds heal three times faster.
erika8213
AI meets zebrafish: is this the future of drug discovery?
04/04/2023
New drug candidates must undergo lengthy testing using animal models before being given to participants in human trials. This means many active ingredients must already be sorted out in test series because they either do not have the desired or even have an adverse effect. These test series require many test animals. The use of zebrafish larvae could lead to a reduced demand in this setting.
Caltech
‘Smart’ bandages monitor wounds and provide targeted treatment
03/04/2023
Most of the time, when someone gets a cut, scrape, burn, or other wound, the body takes care of itself and heals on its own. But this is not always the case. Diabetes can interfere with the healing process and create wounds that will not go away and that could become infected and fester.
YuriArcursPeopleimages
Shining light on aging hearts
30/03/2023
Light therapy has demonstrated its usefulness in treating a variety of diseases. But can it delay the occurrence of age-related disease? The answer may be yes, according to a study in mice published in February in Lasers in Surgery and Medicine.
Fraunhofer ISC
Innovative in vitro eye irritation test to replace standard animal testing
10/03/2023
Researchers at the Translational Center for Regenerative Therapies TLC-RT of the Fraunhofer Institute for Silicate Research ISC want to work with partners to replace animal testing.
Satoshi Tanikawa, et al. 2023
Healing the brain: hydrogels enable neuronal tissue growth
03/03/2023
Synthetic hydrogels were shown to provide an effective scaffold for neuronal tissue growth in areas of brain damage, providing a possible approach for brain tissue reconstruction.
Rawpixel
Packaged DNA: new method to promote bone growth
17/02/2023
DNA can help to stimulate bone healing in a localised and targeted manner, for example after a complicated fracture or after severe tissue loss following surgery.
Vaibhav Srivastava
Mucus-based gel improves bone graft results, promotes healing
14/02/2023
Molecules from mucus can be used to produce synthetic bone graft material and help with the healing of larger bone loss, a new study found.
Fraunhofer ISC
Bioresorbable membrane for healing internal and external wounds
10/02/2023
Fraunhofer researchers have succeeded in using the bioresorbable silica gel Renacer to produce an electrospun membrane that is neither cytotoxic to cells nor genotoxic.
POSTECH
Treating cornea ulcers with diagnostic light instead of corneal transplantation
08/02/2023
Recently, a Korean joint research team from POSTECH-KKU has developed a new tissue adhesive that restores the damaged cornea by simply filling it and exposing it to light.
Beachbumledford
Controlled manufacture, storage and freezing of artificial retinal cells
25/01/2023
Fraunhofer researchers have now developed a new method for the production and clinical application of stem-cell-based retinal implants, which could contribute towards the successful treatment of AMD.
Asociación RUVID
Biomaterial capable of regenerating bones and preventing infections
15/12/2022
Researchers from the Bioengineering and Biomaterials Laboratory of Universidad Católica de Valencia (UCV) have developed a new porous material capable of regenerating bones and preventing infections at the same time.
beta-web/Roth
Wound treatment: printing instead of grafting
01/12/2022
Currently, wound care is limited to either waiting for wounds to heal while keeping them clean and free of infection or using grafts from the patient’s own body to cover larger defects. With the ongoing development tissue engineering and bioprinting, there could be a third option in future: Will we be able to print new tissue directly in the OR to cover surgical wounds?
ARTFULLY79
Technology in wound care: tools for better healing
01/12/2022
Wounds – both acute and chronic ones – can have many different causes. They all have in common that they require meticulous care because complications in wound healing can severely reduce both the patients’ health and quality of life. But there is more to modern wound care than just cleaning and bandaging them. Nursing staff and physicians can also access technical aids for this work.
DegrooteStock
Wound care: healing with technology
01/12/2022
Wound care by nurses is directly about cleaning, sterile covering, and documentation. Medical and surgical interventions may also be necessary. In this context, wound care also offers potential for the use of technical aids that can help prevent complications.
Lena Holm
Scientists develop gel made from spider silk proteins for biomedical applications
19/08/2022
Researchers at Karolinska Institutet in Sweden and the Swedish University of Agricultural Sciences have discovered that spider silk proteins can be fused to biologically active proteins and be converted into a gel at body temperature.
Fibers for fibers – Textile implants repair the body
08/06/2022
We are nowadays already able to weave implants out of artificial fibers that can replace tissue or heal injuries. Different materials like polymers or nitinol are used to create flexible shapes. But the materials and their uses can still be improved.
PantherMedia/npudov
Implants: When technology makes sense – quite literally
01/12/2021
Disease, injury, or a condition you were born with – reasons why some people must live without one or several of their five senses. Fortunately, there are many modern sensory aids that help replace one sense with another, which is especially the case when it comes to vision and hearing. Given technology's advancements, can artificial or biological implants someday soon be a viable alternative?
PantherMedia/Wavebreakmedia (YAYMicro)
Chronic wounds: new, inexpensive wound dressing
29/07/2021
An MSU-led team is developing an inexpensive biopolymer dressing to heal injuries like diabetic foot ulcers that affect millions of patients all over the world.
Intelligent implants: when the material is the key to the solution
01/02/2021
Today we use implants to stabilize or compensate for injuries inside the body and to aid in the healing process. Implants cannot act autonomously and treat the patient if they deem it necessary. However, it is just a matter of time before this happens because research on intelligent implant materials that respond to stimuli is on the cusp of a breakthrough.
Medical products made of collagen - Biocompatible, elastic, stable
19/03/2020
Regenerative medicine often relies on implants and materials that support healing in our body. Collagen has a special significance here. It is compatible to the body and offers an excellent environment for the growing of new cells. In our video, we took a look on where collagen and collagen products for medicine come from.
rhCollagen: genetically engineered building block for regenerative medicine
03/02/2020
Collagen is the stuff that holds our bodies together and that houses our cells. In regenerative medicine, it is also the stuff that can be applied to wounds to support healing. However, collagen from animal or human sources has some drawbacks for today’s medicine. This is where rhCollagen from the Israeli company CollPlant comes into play.
Regenerative medicine: creating a new body?
03/02/2020
Regenerative medicine aims to repair the human body after injuries, accidents or major cancer surgery. Unfortunately, we are still not at a stage where this process can achieve optimal results for every conceivable situation. Having said that, various new methods are on the cusp of breakthrough.
Regenerative medicine: helps the body healing
03/02/2020
Severe wounds heal slowly and leave scars. This is why we have been using regenerative therapies for some time now to accelerate and improve healing. They also help to avoid permanent damage. Still, complex applications like replacing organs or limbs will rather remain vision than become reality for a long time.
Angiogenesis: light shows blood vessels the way
03/02/2020
Regenerative medicine aims to replace damage in the body with functional tissue and restore normal function. The first defense for large defects are implants made of hydrogels, designed to promote cell growth. They need their own blood supply, which is a problem when it comes to larger implants because you cannot regulate where and how the blood vessels grow - until now.
panthermedia.net/kasto
Cardiac Tissue Engineering: a heart out of the Petri dish
23/09/2019
For patients waiting for donor organs, every day can mean the difference between life and death. Making things even more complicated is the fact that not every organ is a compatible match with the patient. It would mean enormous progress if we could grow organs from the patient's own cells in the lab. That's why patients with heart disease place big hope in tissue engineering.
Sports medicine – keep moving to stay healthy
01/07/2019
Physical activity plays a big role in today's society. Whether you are an amateur or professional athlete – incorporating exercise into your life positively impacts your mental and physical health. Ideally, sport should be fun, pressure-free and not overburden you. But can you measure individual performance and align it with sports?
Multi-organ chips: Drug research without animal testing at vasQlab
15/05/2019
New active substances that are suitable for drugs are initially tested in animal experiments. However, the results cannot always be transferred to the human organism. At the Karlsruhe Institute of Technology, Prof. Ute Schepers from vasQlab explains how active substances can be tested in human tissue without endangering human health.