While the larynx is somewhat easier to access than the inner ear, it is no less sensitive. Nerves in this area are susceptible to injury following a variety of interventions such as thyroid surgery, cervical spine or thoracic surgery. As a result, impulses from the brain are no longer transmitted to the vocal folds. They lose muscle tension, which subsequently means the vocal folds can no longer be properly tightened and moved. This prompts vocal fold paralysis, affecting either one or both vocal folds. In a MEDICA-tradefair.com interview, Prof. Andreas Müller from the SRH Wald-Klinikum Gera explains the consequences: "In the case of unilateral vocal fold paralysis, the dominant effect is a voice disorder, meaning the voice sounds hoarse and weak. In bilateral vocal fold paralysis, breathing becomes difficult because the vocal folds cannot open."
There are two approaches to the surgical treatment of this condition: the first one is called reinnervation where nerves in the throat are moved toward the larynx. The impulses transmitted by these nerves cause the muscle tension of the vocal folds to increase. With more complex options of this procedure, this process even partially restores the normal mobility of the vocal folds - and thus the functionality of the larynx.
The implantation of a laryngeal pacemaker system pursues a similar goal. This approach resembles the workings of a heart pacemaker. The device consists of a pulse generator that is implanted in the chest area and two electrodes that are positioned from there to the larynx. The implantation process is minimally invasive to avoid subsequent damage to and around the larynx. The electrodes can bridge the damage to the nerve, which interrupts the connection between the brain and muscle: "However, since there is still a neuromuscular connection, the laryngeal pacemaker system aims to stimulate the target muscle directly behind the site of the nerve injury. This triggers the vocal folds to open," explains Müller, who is involved in approval studies for the laryngeal pacemaker system.