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Image: This image shows two screens. The one of the right shows the word AI and the left some text. On the right side, there is a man looking at the screens.

Prototype applies AI to advance colorectal diagnosis

15.03.2024

Portuguese researchers from the Institute for Systems and Computer Engineering, Technology and Science (INESC TEC) and the IMP Diagnostics Molecular & Anatomic Pathology laboratory have unveiled the world's first prototype applying Artificial Intelligence (AI) to colorectal diagnosis.
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Image: Close-up and 3D illustration of cream-colored molecules on a black background; Copyright: Determined

Determined

A sugar analysis could reveal different types of cancer

22.12.2023

In the future, a little saliva may be enough to detect an incipient cancer. Researchers at the University of Gothenburg have developed an effective way to interpret the changes in sugar molecules that occur in cancer cells.
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Image: AI-based segmentation of melanoma metastases in a tumor; Copyright: USZ

USZ

Understanding and fighting tumors better with new algorithms

21.12.2023

The University Hospital Zurich, the University of Zurich and the diagnostics company Roche are expanding their collaboration in cancer research. In the fully digitalized Morphomolecular Pathology Laboratory, they are developing algorithms that can further improve the effectiveness of immunotherapies.
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Image: Blue and white logo from the EU consortium CERTAINTY; Copyright: Fraunhofer-Gesellschaft

Fraunhofer-Gesellschaft

CERTAINTY: virtual twin for improved cancer immunotherapies

20.12.2023

Together with partners from science, industry and the healthcare sector, the project team led by the Fraunhofer Institute for Cell Therapy and Immunology IZI aims to develop a virtual twin that will improve treatment with personalized cancer immunotherapies in the future.
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Image: 3D simulation of an active material in a geometric shape resembling a dividing cell; Copyright: Singh et al. Physics of Fluids (2023) / MPI-CBG

Singh et al. Physics of Fluids (2023) / MPI-CBG

New computer code for mechanics of tissues and cells in three dimensions

28.11.2023

Open-source supercomputer algorithm predicts patterning and dynamics of living materials and enables studying their behavior in space and time.
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Image: Hands of a surgeon on the control console of a surgical robot; Copyright: Gerain0812

Gerain0812

Sensor-controlled precision: the future of surgical tumor removal

22.08.2023

The complete removal of malignant tumors is a decisive factor for the success of cancer treatment. Until now, the tissue examinations required for this have been time-consuming. In the future, sensor-based methods could come into play to help surgeons detect tumor boundaries more accurately and thus perform a more precise operation.
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Image: It shows the activation of a chemical signaling pathway (ERK pathway; top-right) merged with a simulation of 2D cell areas (bottom-left) in a monolayer of cells; Copyright: Hannezo Group | ISTA

Hannezo Group | ISTA

Cell dynamics: how cells talk to each other

26.07.2023

Like us, cells communicate. Well, in their own special way. Using waves as their common language, cells tell one another where and when to move.
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Image: Images of complex brain structures. On the left these structures are difficult to see, on the right they are shown more clearly; Copyright: Johann Danzl

Johann Danzl

Brain: LIONESS enables insights into complex tissue

13.07.2023

In a new paper, an interdisciplinary team of scientists at the Institute of Science and Technology Austria (ISTA) has come together to present a new way to observe the brain’s structure and dynamics – in a high resolution and without damaging the tissue.
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Image: Two men and three women pose in white coats in a laboratory; Copyright: Universidad de Barcelona

Universidad de Barcelona

New biomarkers of non-small cell lung cancer discovered

27.06.2023

Researchers of the University of Barcelona and the Institute of Bioengineering of Catalonia (IBEC) have identified new biomarkers for non-small cell lung cancer, the most common lung cancer.
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Image: Two women, Wiebke Möbius and Sophie Hümmert, at a white electron microscope; Copyright: Swen Pförtner MPI

Swen Pförtner MPI

Multiple Sclerosis: structural changes in brain tissue promote inflammatory processes

31.05.2023

A German-Dutch research team has shown that ultrastructural changes in healthy areas in the white matter of MS patients make the tissue more susceptible to inflammation and the formation of lesions
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Image: OR monitor that shows heart rate and other vital parameters, behind it an OR team; Copyright: bilanol

bilanol

OptoCarDi: searching for new diagnostic options to assess the heart muscle

16.05.2023

The preparations for the OptoCarDi project at the EAH Jena and the Jena University Hospital (UKJ) are in full swing. Starting in June 2023, a research team led by Prof. Iwan Schie (Biomedical Engineering), Prof. Robert Brunner (Miniaturized Optical Sensor Systems) and the cardiologists Prof. Sven Möbius-Winkler and Prof. Christian Schulze will develop an optical catheter prototype.
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Image: 3D-segmentation of different structures related to an infection with the Ebola virus.; Copyright: Petr Chlanda

Petr Chlanda

Luring the virus into a trap

04.05.2023

Heidelberg researchers describe mechanisms that could help prevent infections with the influenza A and Ebola viruses.
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Image: A spoon piled with bits of plastic. The spoon lies on a salmon-colored background; Copyright: xalien/Shutterstock

xalien/Shutterstock

Tiny plastic particles also find their way into the brain

28.04.2023

With the help of computer models, researchers have discovered that a specific surface structure (biomolecular corona) is crucial for the passage of plastic particles into the brain.
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Image: An example of virtual staining of tissue. Unstained tissue on the left, chemically stained tissue in the middle and virtually stained tissue on the right; Copyright: Pekka Ruusuvuori

Pekka Ruusuvuori

AI-based method to replace chemical staining of tissue

21.04.2023

Researchers have developed an artificial intelligence-based method for virtual staining of histopathological tissue samples as a part of the Nordic ABCAP consortium.
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Image: Microscopic image: Mouse lymph nodes with colored fluorescent markers; Copyright: AG Hoelzel/UKB

AG Hoelzel/UKB

Artificial intelligence to help tumor immunology

09.03.2023

Developing methods to predict the nature of the tumor microenvironment is the goal of researchers from the Clusters of Excellence ImmunoSensation2 and the Hausdorff Center for Mathematics (HCM) led by Prof. Kevin Thurley at the University of Bonn.
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Image: Two men in white laboratory clothing are working on new quantum light modules; Copyright: FBH/P. Immerz

FBH/P. Immerz

Entangled photon pairs to help fighting cancer

06.03.2023

The recently launched QEED project aims to significantly reduce measurement time in clinical cancer diagnostics by developing a spectrally resolved imaging technique based on entangled photon pairs. FBH scientists will develop the required diode lasers and quantum light modules.
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Image: Mattias Ekstedt, senior associate professor at Linköping smiles at the camera; Copyright: Thor Balkhed/Linköping University

Thor Balkhed/Linköping University

Adverse muscle composition associated with increased mortality risk in people with fatty liver disease

01.03.2023

Obesity and a sedentary lifestyle contribute to an increasing number of people developing fatty liver disease. There is a need for early detection of individuals at risk of developing sequelae.
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Image: Two men and a woman stand in front of a building and smile for the camera; Copyright: RUB, Marquard

RUB, Marquard

AI with infrared imaging enables precise colon cancer diagnostics

23.02.2023

Researchers at the Centre for Protein Diagnostics PRODI at Ruhr University Bochum, Germany, are using artificial intelligence in combination with infrared imaging to optimally tailor colon cancer therapy to individual patients.
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Bild: Close-up of a laboratory technician, he tests a sample using a spectrometer in the laboratory, fills the sample into the cuvette; Copyright: kwanruanp

kwanruanp

DZHK establishes two central biobanks - cooperation partners welcome

16.01.2023

The German Center for Cardiovascular Research is centralizing its biospecimens collections, which are currently stored at 60 sites. Therefore, it is looking for two biobanks as scientific cooperation partners. Applications are now open to all German biobanks.
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Home for medical technology – Highlight tour at the joint stand of NRW

16.11.2022

North Rhine-Westphalia offers good conditions as a location for medical technology companies. We spoke to Refined Laser Systems GmbH, United Robotics Group GmbH and weLLgo Medical Products GmbH during our tour of the NRW joint stand in Hall 3 / C80.
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Image: small empty test tubes with lids in different colors; Copyright: Messe Düsseldorf/C. Tillmann

Messe Düsseldorf/C. Tillmann

RNA technologies make targeted immune activation possible

03.11.2022

MEDICA 2022 is right around the corner, ready to deliver insights into the advancements and innovations in laboratory medicine. One of the key topics of the MEDICA LABMED Forum is RNA technologies and the wide range of applications that involve cell biology. RNA technologies not only enable Covid-19 vaccines but promise an array of treatment options for genetic diseases, in and beyond oncology.
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Image: Person in the laboratory holding cell samples under a microscope; Copyright: MICROGEN@GMAIL.COM

MICROGEN@GMAIL.COM

Molecular markers: predicting the most effective treatment for IBD

09.08.2022

Early effective treatment can help manage this condition and improve the quality of life of patients. A research project aims to identify molecular markers to better assess the chances of success of certain biological therapies and subsequently determine the best individualized treatment plan.
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Image: Professor Dr. Danny Jonigk and Christopher Werlein; Copyright: Karin Kaiser / MHH

Karin Kaiser / MHH

New X-ray technique shows vascular damage in intact COVID-19 lungs for first time

05.11.2021

When the coronavirus enters the lung, it causes massive tissue damage. Now, an international research team has been able to demonstrate for the first time, using a highly innovative X-ray technique in a non-destructive manner, that severe COVID-19 causes massive remodelling of the finest blood vessels by causing normally separate blood systems to join together with unusual frequency.
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Image: a robot arm holding a small glass; Copyright: PantherMedia / Bork

PantherMedia / Bork

The smart lab: Between manual work and digitization

01.10.2021

In the laboratory, there is some work that is time-consuming and monotonous – making it the perfect place for digital solutions such as artificial intelligence or robotics. But what work can these systems really take on in a meaningful way, in which areas of the lab are they present today, and where do they still need to be improved?
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Image: UV Visual Lift; Copyright: by UVentions

by UVentions

Hygiene: Smart protection against pathogens like the coronavirus

23.03.2020

Germs such as bacteria, viruses or pathogenic fungi can spread from one person to another through direct contact when we shake hands or touch objects. People touch door handles and push elevator buttons in public places and constantly move in and out of spaces. Regular manual high-level disinfection is practically impossible. UVentions GmbH has found an intelligent solution for this problem.
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Image: Two screens with picture of the circulatory system in a catheter laboratory; Copyright: panthermedia.net/sudok1

MEDICA TECH FORUM: light-based imaging technique OCT

04.11.2019

Since its inception, MEDICA TECH FORUM has focused on the implementation of innovations and new technologies into clinical practice. 2019 marks the tenth year of the Forum. In honor of its anniversary, we will brighten things up a bit, as one of the focal points will highlight how optical coherence tomography (OCT) uses light to produce images.
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Image: Laboratory situation - Prof. Popp shows a young man a small object in his hand; Copyright: Leibniz-IPHT/Sven Döring

Leibniz-IPHT/Sven Döring

Tumor excision: triple imaging for unique diagnostics

08.08.2019

After their tumor has been removed, some patients have to return to the hospital to undergo surgery again. That's because the tumor was not precisely identified and was subsequently not completely removed. That's both an ethical and financial dilemma. A new surgery-adjacent procedure is designed to rapidly and accurately detect tumors.
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Image: A greenly lit laboratory device; Copyright: Sven Döring

Photonics: "We want a rapid and easy method to identify pathogens and antibiotic resistance"

01.08.2019

The medical devices value chain has gaps between academic research and industrial practice that slow down innovation processes. This also applies to time-sensitive and urgently needed products such as rapid diagnostic tests to identify resistant pathogens. At the InfectoGnostics Research Campus in Jena, partners from research and medicine team up to close these gaps.
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Multi-organ chips: Drug research without animal testing at vasQlab

15.05.2019

New active substances that are suitable for drugs are initially tested in animal experiments. However, the results cannot always be transferred to the human organism. At the Karlsruhe Institute of Technology, Prof. Ute Schepers from vasQlab explains how active substances can be tested in human tissue without endangering human health.
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Image: Graphic rendering of several cells in a petri dish; Copyright: panthermedia.net/dani3315

Organ-on-a-chip systems: limited validity?

01.02.2019

Organ-on-a-chip systems are technically a great enhancement of medical research because they facilitate testing of active ingredients on cell cultures in the chambers of a plastic chip. This replaces animal testing and improves patient safety. That being said, they are not a true-to-life replication of the human body and can only simulate a few functions and activities.
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