Oxford Nanopore
Nanopore sequencing and DNA barcoding method gives hope of personalised medicine
03.10.2023
With the ability to map dozens of biomarkers at once, a new method could transform testing for conditions including heart disease and cancer.
Christian Wißler/UBT
EXIST funding for bacterial magnetic nanoparticles
28.09.2023
BioMagnetix uses bacterial magnetic nanoparticles as innovative materials for biomedical applications. The founding team aims to develop and continuously improve high-quality and highly functional magnetic nanoparticles for imaging techniques and therapeutic purposes, such as cancer treatment.
svitlanah
New blood marker can identify parkinsonian diseases
20.09.2023
Is it possible that a single biomarker can detect all types of diseases related to dopamine deficiency in the brain? Yes, that's what a research group in Lund is discovering.
Ryan Hull
Pathogen detection through electronic detection of DNA nanoballs
19.09.2023
Researchers at Karolinska Institute have developed a novel method using DNA Nanoballs to detect pathogens, aiming to simplify nucleic acid testing and revolutionize pathogen detection.
seventyfourimages
New blood test gives very high accuracy to screen for Alzheimer’s disease
08.09.2023
A new blood test called p-tau217 shows promise as an Alzheimer's disease biomarker, and when used in a two-step workflow very high accuracy to either identify or exclude brain amyloidosis, the most important and earliest pathology.
Joakim Palmqvist
Advanced biosensors to detect tumors, viruses and bacterial diseases
06.09.2023
Linnaeus University is partnering with industry and healthcare to develop advanced biosensors, investing SEK 35 million in a project aimed at faster and cost-effective diagnoses of aggressive lung cancer, viral, and bacterial diseases, potentially enabling self-testing at home.
Karin Kaiser / MHH
More impact against cancer
04.09.2023
MHH molecular physician Professor Dr. Dr. Schambach wants to use genetically modified natural killer cells to find new therapeutic options against three particularly malignant cancers. The EU is funding the project with 3.8 million euros
Kateryna Maksymenko
Innovative computational approach helps design proteins for cancer treatment
31.08.2023
A joint team of researchers from the Max Planck Institute for Biology Tübingen and the University Hospital Tübingen has now developed and tested a new computational method to greatly speed up the necessary energy calculations.
Anne Günther/Uni Jena
Timing is key in cortisone treatment of inflammation
30.08.2023
A special type of starch could soon be used as an excipient in medicine to improve the treatment of patients.
lassedesignen/Shutterstock
Multiple sclerosis: new biomarker for early diagnosis
12.07.2023
A study conducted by researchers from the Department of Neurology at MedUni Vienna and University Hospital Vienna has demonstrated for the first time that diagnosis of multiple sclerosis (MS) can be significantly improved by additionally measuring the thickness of retinal layers in the eye.
Prostock-studio
Molecular tumor profiling: blood test to determine the optimal cancer therapy
11.07.2023
If a tumor is diagnosed, tissue samples are usually investigated to determine the molecular tumor profile for personalized cancer treatment. However, tissue biopsy cannot be performed in all affected individuals. Therefore, the University Hospital Zurich has licensed a liquid biopsy for the analysis of more than 300 genes and offers this test as a modern diagnostic method to tumor patients.
Dmitry_Rukhlenko
ETERNITY: EU graduate training on metabolism and neurodegeneration
04.07.2023
In a new, EU funded program, early career scientists are tracking down the connection between metabolic disorders and neurodegenerative diseases. DZNE is involved in a leading role.
Alex Dolce, Florida Atlantic University
Sickle cell disease: portable tool for diagnosis, monitoring receives U.S. patent
30.06.2023
Using microfluidics, flow cytometry and electrical impedance, Sarah Du recently received a patent from the United States Patent and Trademark Office for a novel invention that will offer patients a better way to manage their disease.
University Hospital of Bonn (UKB)
Metastatic renal cell carcinoma: improved prediction of therapy response
29.06.2023
The study demonstrates a significant improvement in predicting the response to therapy in metastatic renal cell carcinoma by incorporating the level of inflammation, which was assessed using two straightforward blood parameters, alongside the conventional imaging-based approach.
Universidad de Barcelona
New biomarkers of non-small cell lung cancer discovered
27.06.2023
Researchers of the University of Barcelona and the Institute of Bioengineering of Catalonia (IBEC) have identified new biomarkers for non-small cell lung cancer, the most common lung cancer.
seventyfourimages
Blood biomarkers plus genomics in the prediction of disease risk
16.06.2023
Being to identify people at high risk of chronic disease means that they can be targeted with prevention measures before they become sick. Polygenic risk scores, where genomic information alone is used to assess the risk of developing diseases, have been receiving a lot of attention recently.
Pixabay
Lung: bacterial colonisation also depends on genes of the host
13.06.2023
We know from previous studies that changes in the lung microbiome are associated with diseases such as cystic fibrosis, asthma or chronic obstructive pulmonary disease (COPD). Environmental factors such as smoking, nutrition in infancy or the use of antibiotics are important factors for the composition and stability of the microbial community in the lung.
mirarahneva
Neurosurgery: blood tests can show impact on the brain
31.05.2023
Damage to the brains of patients operated on for brain tumors may be assessed by measuring biomarkers in the blood pre- and postoperatively. A new study by University of Gothenburg researchers shows that the increase in markers tallies well with the impairment caused by insufficient blood flow.
Karolinska Institutet
New method reveals bacterial reaction to antibiotics in five minutes
26.05.2023
Researchers at Karolinska Institutet in Sweden have developed a molecular method able to detect whether or not bacteria respond to antibiotics within minutes.
Prostock-studio
TimeTeller: tenth spin-off of the BIH Digital Health Accelerator
25.05.2023
An interdisciplinary team led by Prof. Angelo Relógio, a scientist at Charité’s Molecular Cancer Research Center (MKFZ) and Institute for Theoretical Biology and the MSH Medical School Hamburg, has developed a non-invasive method for profiling a person’s unique circadian rhythm.
Anna Schroll/Leibniz-HKI
Model shows intestinal bacteria influence growth of fungi
22.05.2023
The bacteria present in the intestine provide information about the quantities of fungi of the potentially disease-causing Candida genus.
European Cooperation in Science and Technology
Imaging chronic kidney disease
12.05.2023
Magnetic Resonance Imaging (MRI) has shown a high potential to distinguish biomarkers for CKD, but renal MRI biomarkers are currently underused in research and clinical practice.
Universidad de Barcelona
Microfluidics physics-based device to predict cancer therapy response
06.04.2023
A team of experts has designed a microfluidic device called microfluidic dynamic BH3 profiling (μDBP) that predicts the effectiveness of cancer treatment quickly and automatically.
Gustavo Raskosky/Rice University
Upgraded tumor model optimizes search for cancer therapies
27.03.2023
Rice University researchers developed an upgraded tumor model that houses osteosarcoma cells beside immune cells known as macrophages inside a three-dimensional structure engineered to mimic bone. Using the model, bioengineer Antonios Mikos and collaborators found that the body’s immune response can make tumor cells more resistant to chemotherapy.
JoPanwatD
AI finds targets for CAR-T cell therapy against acute myeloid leukemia
20.03.2023
Unlike other forms of blood cancer, acute myeloid leukemia (AML) cannot currently be treated with CAR-T cell immunotherapy. The reason is that specific molecular targets with which certain immune cells could specifically target AML cells are lacking, which would permit the immune system to attack cancer.
grafvision
Epilepsy could become easier to pinpoint with blood test
17.03.2023
Researchers from Lund University in Sweden have discovered higher levels of immune proteins in the blood before and after an epileptic seizure.
Rawpixel
Bracelet sensor assesses troponin levels to aid heart attack diagnosis
13.03.2023
An experimental wrist-worn device was found to predict troponin-I and obstructed arteries with 90% accuracy in five minutes, according to research.
Eurice Office
Personalised health blueprint to prevent and predict inflammatory bowel disease
07.03.2023
Project led by PMI member Prof. Andre Franke aims to empower people affected by Crohn’s disease and ulcerative colitis by developing interdisciplinary solutions for improved disease prevention and health promotion.
RUB, Marquard
AI with infrared imaging enables precise colon cancer diagnostics
23.02.2023
Researchers at the Centre for Protein Diagnostics PRODI at Ruhr University Bochum, Germany, are using artificial intelligence in combination with infrared imaging to optimally tailor colon cancer therapy to individual patients.
Pressmaster
AI analyses cell movement under the microscope
22.02.2023
The enormous amount of data obtained by filming biological processes using a microscope has previously been an obstacle for analyses.
HAWK
Imaging: role of immune cells in early diabetic cataract development
22.02.2023
The team of researchers, led by Prof. Dr. Ali Hafezi-Moghadam, Director of the Molecular Biomarkers Nano-Imaging Laboratory (MBNI), in collaboration with Professor Dr. Christoph Rußmann, Dean of the Health Campus and a Visiting Professor at MBNI, found early signs of damage in the eye before the onset of type 2 diabetes.
Vaibhav Srivastava
Mucus-based gel improves bone graft results, promotes healing
14.02.2023
Molecules from mucus can be used to produce synthetic bone graft material and help with the healing of larger bone loss, a new study found.
Image-Source
Predicting dementia using neural network characteristics
13.02.2023
In many neurodegenerative conditions, brain changes occur before symptoms emerge. But now, researchers from Japan have found a new way to distinguish these conditions in the early stages according to changes in brain activity patterns.
private
Smart clothing and Artificial Intelligence: Diagnosis and monitoring of neurological diseases
01.02.2023
International research groups led by Prof. Dr. Aldo Faisal, Professor of Digital Health at the University of Bayreuth, have developed a novel set of tools for diagnosing and monitoring neurological diseases based on body-worn sensors (wearables) and artificial intelligence.
Karin Kaiser / MHH, Freepik.com
MHH leads EU large-scale project for personalized cancer care
26.01.2023
CAN.HEAL aims to expand the available innovations in cancer prevention, diagnosis and treatment in the Member States in order to improve care for all patients in the EU. The project focuses on measures of personalized medicine. Genomics is an important cornerstone for this.
gstockstudio
New blood test differentiates neurodegeneration in Alzheimer’s disease from other dementias
23.01.2023
A new blood test that can track and follow the neurodegeneration in Alzheimer’s disease – and exclude other dementias.
National University of Singapore
Scientists identify blood biomarker for cognitive impairment and dementia
02.01.2023
A recent study by a team comprising researchers from the National University of Singapore (NUS) and the National University Health System (NUHS) revealed that low levels of ergothioneine (ET) in blood plasma may predict an increased risk of cognitive impairment and dementia, suggesting possible therapeutic or early screening measures for cognitive impairment and dementia in the elderly.
DC_Studio
Diagnosing breast cancer through liquid biopsy
22.09.2022
Breast cancer diagnosis usually includes invasive testing with tissue biopsies. The samples have to be extracted from the cancerous tissue or cells. To make the process easier on the patients, the project LIBIMEDOTS is currently developing a different approach with liquid biopsy technology.
MICROGEN@GMAIL.COM
Molecular markers: predicting the most effective treatment for IBD
09.08.2022
Early effective treatment can help manage this condition and improve the quality of life of patients. A research project aims to identify molecular markers to better assess the chances of success of certain biological therapies and subsequently determine the best individualized treatment plan.
LipiTUM
MoSBi: Algorithm identifies disease subtypes
01.08.2022
Doctors have always used symptoms, imaging, and laboratory data to define and diagnose diseases, but at times it is simply not enough: while patients may have the same illness, it may exhibit different changes at the molecular level. A team from the Technical University of Munich has developed the so-called MoSBi algorithm and makes it available to researchers to identify molecular differences.
PantherMedia / angellodeco
The smart lab: The shift to more digitization is picking up speed
01.10.2021
They have probably never been in the spotlight as much as during the pandemic: laboratories. In Germany alone, around 73 million COVID-19-tests have been evaluated since the beginning of 2020. And even away from Corona, laboratory physicians have a lot to do – blood, urine and aspirates have to be evaluated every day. That results in an enormous amount of work, just in terms of organization.
McGill University
A skin crawling treatment for acne
01.09.2021
Drawing inspiration from nature, a team of international scientists have invented a smart device for personalized skin care modeled after the male diving beetle. This tool collects and monitors body fluids while sticking to the skin’s surface, paving the way for more accurate diagnostics and treatment for skin diseases and conditions like acne.
Intelligent implants: when the material is the key to the solution
01.02.2021
Today we use implants to stabilize or compensate for injuries inside the body and to aid in the healing process. Implants cannot act autonomously and treat the patient if they deem it necessary. However, it is just a matter of time before this happens because research on intelligent implant materials that respond to stimuli is on the cusp of a breakthrough.
Vivatmo me: monitor your asthma treatment at home
01.01.2021
Allergic asthma is a chronic disease that makes regular monitoring essential to keep it under control. This is the only way to determine whether the prescribed medication is effective or whether the patient needs a treatment adjustment. Vivatmo me is a breath analyzer device for home use and helps keep asthma patients safe and confident between visits to the doctor.
panthermedia.net/olanstock
Cardiac diagnostics – prompt and personalized
08.11.2019
If physicians suspect an acute myocardial infarction, they first order an ECG. This test is very established and allows cardiologists to quickly diagnose acute heart attacks – though the test does not detect less common heart attack symptoms. So far, those patients had to wait up to twelve hours before a heart attack could be accurately diagnosed or ruled out. But things are about the change.
Functional Imaging: The puls of modern oncology
17.06.2019
Medical imaging techniques have developed considerably in recent decades. In addition to morphological imaging techniques more and more functional imaging techniques are used in oncology that can continously record the functions of specific organs locally and regionally in real time. These are groundbreaking for diagnostics, therapies and preoperative preparations.