30.08.2023A special type of starch could soon be used as an excipient in medicine to improve the treatment of patients.
30.08.2023A special type of starch could soon be used as an excipient in medicine to improve the treatment of patients.
29.08.2023Cooperation between the University of Bonn, the USA and the Netherlands cracks the mode of action of clovibactin
25.08.2023Cooking food thoroughly and avoiding some types of vegetables and salad during a course of antibiotic treatment could potentially reduce antibiotic resistance, by preventing bacteria carrying resistance genes getting into the gut, according to a new study.
02.08.2023A team of researchers from the Universitat Politècnica de València (UPV) has participated in the development of Epileptika. This application aims to help the treatment of refractory epilepsy in people with intellectual disability.
27.07.2023The high cost and limited commercial value of new antibiotics discourage their development, as they are used sparingly to avoid resistance. To address this, a new robotics platform aims to simplify the development of active substances to combat the problem of antibiotic resistance. While we cannot always prevent resistance, this approach offers a promising solution.
27.07.2023In a paper published in the journal Science, a team at the Technical University of Munich (TUM) shows that heart diseases affect the production of the sleep hormone melatonin in the pineal gland.
20.07.2023Artificial intelligence is becoming increasingly important in drug discovery. Advances in the use of Big Data, learning algorithms and powerful computers have now enabled researchers at the University of Zurich (UZH) to better understand a serious metabolic disease.
21.06.2023Two new assistant professors at the University of Bonn are setting out to develop “mini-organs” in order to study metabolic and disease mechanisms.
01.06.2023Thanks to the radiation they emit, radioactive compounds are suited both to imaging and treating cancers. By appropriately combining them in novel, so-called radionuclide theranostics, both applications can be dovetailed.
29.05.2023A group of Computer Scientists from the Max Planck Institute for Informatics in Saarbrücken, Germany, and the University of California at Davis, have invented a process that relies solely on the shape of the object for a time-controlled release.
26.05.2023Researchers at Karolinska Institutet in Sweden have developed a molecular method able to detect whether or not bacteria respond to antibiotics within minutes.
25.05.2023An interdisciplinary team led by Prof. Angelo Relógio, a scientist at Charité’s Molecular Cancer Research Center (MKFZ) and Institute for Theoretical Biology and the MSH Medical School Hamburg, has developed a non-invasive method for profiling a person’s unique circadian rhythm.
18.05.2023A new advanced artificial intelligence (AI) system has shown world-leading accuracy and speed in identifying protein patterns within individual cells.
09.05.2023A team led by bioinformatics experts Andreas Keller and Fabian Kern from Saarland University together with researchers at Stanford University have gained new insights into manifestations of ageing at the molecular level.
08.05.2023An interdisciplinary team of scientists in Dresden developed novel bio-inspired sugar-based molecules that show potential to improve bone regeneration.
04.05.2023When the heart gets out of rhythm, characteristic processes occur in the heart muscle cells. Among other things, the currents of electrically charged particles (ions) change. In chronic atrial fibrillation, one of these currents is reduced.
02.05.2023“We have developed a technique in our laboratories that allows us to obtain an antibiogram within 2-4 hours – instead of the current 24 hours for the most common germs and one month for tuberculosis,” says Dr Sandor Kasas at EPFL.
14.04.2023Chemotherapy treatments produce strong side effects. A new agent that accumulates in the tumour tissue and is activated there by ultrasound waves does not have this problem.
12.04.2023In a joint project of the Max Planck Institute for Polymer Research, Mainz, and the Translational Center for Regenerative Therapies at the Fraunhofer Institute for Silicate Research ISC, Würzburg, scientific principles and biomaterials for the standardized production of valid tissue models are to be developed.
04.04.2023New drug candidates must undergo lengthy testing using animal models before being given to participants in human trials. This means many active ingredients must already be sorted out in test series because they either do not have the desired or even have an adverse effect. These test series require many test animals. The use of zebrafish larvae could lead to a reduced demand in this setting.
31.03.2023Andreas Dräger from the University of Tübingen is working on a computer-based method that can help to accelerate the time-consuming identification and development of antiviral agents.
28.03.2023A pioneering behavioural diagnostic tool developed by Kingston University, London and healthcare technology company Observia to help patients take their medication as prescribed is the first holistic model in the world to accurately predict hospital admissions and readmissions in people living with Type 2 Diabetes, according to a new study.
27.03.2023Rice University researchers developed an upgraded tumor model that houses osteosarcoma cells beside immune cells known as macrophages inside a three-dimensional structure engineered to mimic bone. Using the model, bioengineer Antonios Mikos and collaborators found that the body’s immune response can make tumor cells more resistant to chemotherapy.
24.03.2023Together with partners from science and industry, Fraunhofer IPK is researching how mRNA therapeutics and other medication can be better produced and more effectively applied.
15.03.2023Technology developed at the University of Freiburg enables experimental test. The new findings could help to improve the transport of active substances into cells
15.03.2023Congenital diaphragmatic hernia is one of the deadliest birth defects. To better understand and treat this condition in the future, an international team of researchers involving Leipzig University Hospital designed a new cell model in the laboratory and tested a drug therapy on it.
14.03.2023The technological basis is a proprietary platform technology for the discovery of drugs that target cancer-causing protein-protein interactions (PPIs).
03.03.2023A research group at Uppsala University has developed a simple and effective artificial blood-brain barrier model that can be used to determine how well antibody-based therapies can enter the brain.
27.02.2023In the ImageTox project, the Helmholtz Institute for Pharmaceutical Research Saarland (HIPS) and the CISPA Helmholtz Center for Information Security are pooling their expertise in the fields of drug discovery and artificial intelligence (AI).
23.02.2023In the ImageTox project, the Helmholtz Institute for Pharmaceutical Research Saarland (HIPS) and the CISPA Helmholtz Center for Information Security are pooling their expertise in the fields of drug discovery and artificial intelligence (AI).
16.02.2023A team led by Prof Claus-Michael Lehr of the Helmholtz Institute for Pharmaceutical Research Saarland (HIPS) has developed a novel human lung cell line that should enable much more accurate predictions of the behavior of active substances or dosage forms in humans than previous systems.
15.02.2023Gattefossé, InProcess-LSP, Knauer, Microfluidics, Skyepharma, and the University of Graz join the RCPE-led European Consortium for Continuous Pharmaceutical Manufacturing (ECCPM) to jointly develop a modular, flexible toolkit to advance industrial-scale production of lipid nanoparticles.
10.02.2023Fraunhofer researchers have succeeded in using the bioresorbable silica gel Renacer to produce an electrospun membrane that is neither cytotoxic to cells nor genotoxic.
08.02.2023A new junior research group at Freie Universität Berlin, which will investigate the production of biodegradable antiviral and antibacterial materials, with one of the goals of synthesis being new alternatives to conventional antibiotics, will receive a total budget of more than 1.8 million euros from the German Federal Ministry of Education and Research (BMBF) over the next five years.
01.02.2023Scientists at the Max Planck Institute for Polymer Research have now followed the path of such a particle into a cell using a combination of several microscopy methods. They were able to observe a cell-internal process that effectively separates blood components and nanoparticles.
27.01.2023The electrical potential across the bacterial cell envelope indicates when bacteria no longer operate as individual cells but as a collective. Researchers at the University of Cologne's Institute for Biological Physics have discovered this connection between the electrical properties and the lifestyle of bacteria.
23.01.2023Rapid switching between different antibiotics could prevent the evolution of resistance and lead to successful treatment of patients.
13.01.2023Two Dresden research institutes want to reduce the number of animal experiments in radiopharmaceutical research with a new idea.
11.01.2022There are many factors to consider when you plan to enter the medical market in another country. Every country requires different market entry strategies – and countries in Africa are no exception.
01.02.2021Today we use implants to stabilize or compensate for injuries inside the body and to aid in the healing process. Implants cannot act autonomously and treat the patient if they deem it necessary. However, it is just a matter of time before this happens because research on intelligent implant materials that respond to stimuli is on the cusp of a breakthrough.
01.02.2021Therapies need to be carried out with high reliability by trained personal. This will not change in the future. But maybe we will be able to let systems in the patient’s body do some of the work. Some approaches are already aiming to make implants more independent so they will be able to flexibly react to changes. Read more in our Topic of the Month!
01.02.2021Drugs always have undesired side effects. Cytostatics are powerful drugs used to treat cancer. They reach almost all cells in the body, killing healthy cells as well as cancer cells in the process. A targeted delivery to the specific cellular site would be a gentler treatment.
08.05.2020A conversation between the patient and the doctor is always at the start of the health journey. The idea is to set the stage and share important information. This process can be shortened if information is already available in digital form. In the future, patients can submit their medication plan via app thanks to "eMMa".
04.11.2019Soon, the world's largest trade fair for medical technology will open its doors again: More than 5.000 exhibitors will present their newest products and ideas at MEDICA from 18 to 21 November. You will not only meet well-known companies here, but also lots of young start-ups. Or, you can visit the MEDICA forums and conferences to experience a rich program of lectures and discussions.
01.08.2019Antibiotic resistance is modern medicine's greatest challenge. Some bacteria only respond to a handful of antibiotics, prompting hospitals to spend a lot of time finding an effective drug. That’s why it is critical for physicians to rapidly identify antibiotic resistance to avoid ineffective treatments.
01.08.2019The medical devices value chain has gaps between academic research and industrial practice that slow down innovation processes. This also applies to time-sensitive and urgently needed products such as rapid diagnostic tests to identify resistant pathogens. At the InfectoGnostics Research Campus in Jena, partners from research and medicine team up to close these gaps.
01.08.2019Antibiotic resistance is on the rise in all parts of the world, complicating medical treatment of serious bacterial infections in patients. The World Health Organization estimates that approximately 33,000 people die each year from antibiotic-resistant bacteria in Europe alone. Bacteria that are resistant to multiple or even all known antibiotics pose an ever-increasing threat.
01.08.2019An untreatable infection is a nightmare for physicians and potentially life-threatening to the patient. Unfortunately, more and more pathogens emerge that are resistant to drugs, especially antibiotics. We need to use our drugs smartly and come up with technical solutions as well to prevent our weapons from blunting in the future.
15.05.2019New active substances that are suitable for drugs are initially tested in animal experiments. However, the results cannot always be transferred to the human organism. At the Karlsruhe Institute of Technology, Prof. Ute Schepers from vasQlab explains how active substances can be tested in human tissue without endangering human health.
01.03.2019COPD is considered the third most common cause of death worldwide and mainly affects smokers. It is not curable, but with the right combination of early diagnosis, therapy and self-management, a significant part of the quality of life can be regained. The comprehensive care is supported by various devices and technical tools. Learn more about the all-round care of COPD in our Topic of the Month.
01.03.2019COPD affects more than 200 million people in the world. Those affected by this chronic pulmonary disease are often slow to notice the symptoms and get a medical diagnosis. This results in secondary complications and high medical costs. That's why an early diagnosis, comprehensive treatment, and frequent monitoring are very important. Various devices and tools support this all-round care.
22.02.2019According to the WHO, ten percent of babies worldwide are born prematurely. Since most organs of these tiny babies have not fully developed yet, it can quickly lead to complications and disorders and most notably affect the lungs of the premature infants. What's more, infections require gentle treatment, as the preemies themselves are fragile and susceptible – making this a challenging situation.