Bernhard-Nocht-Institut für Tropenmedizin
Panadea Diagnostics: new start-up for better infection diagnostics
06.06.2023
"Get the right result, every time": the start-up Panadea Diagnostics has set this as the goal of its work. Operating since April 2023, the biotechnology company founded by researchers at Hamburg's Bernhard Nocht Institute for Tropical Medicine (BNITM) develops special technologies for antibody detection of tropical and emerging infectious diseases.
NTU Singapore
Why wavy wounds heal faster than straight wounds
19.05.2023
Wavy wounds heal faster than straight wounds because shapes influence cell movements, a team of researchers at Nanyang Technological University, Singapore (NTU Singapore) has found.
DZNE/AG Milovanovic
Tuning brain cells with light
11.05.2023
An international research team, comprising scientists from University Hospital Bonn, DZNE, the Netherlands, and the US has been awarded a US$ 1.3 million grant by the “Human Frontier Science Program” to investigate brain immune cells and manipulate them via light irradiation.
Messe Düsseldorf
With stem cell model on the trail of congenital diaphragmatic hernia
09.05.2023
Researchers have designed a new stem cell model to study congenital diaphragmatic hernia in newborns with underdeveloped lungs. They were able to isolate stem cells from the fluid that is suctioned from the baby’s lungs and normally gets discarded and use them as a foundation for the model.
Max Planck Institute for Molecular Biomedicine
Microelectrode array: hammock for brain organoids
20.04.2023
Novel microelectrode array system enables long-term cultivation and electrophysiological analyses of brain organoids.
Cyborg and Bionic Systems
Bioprinting technology and AI enable high quality in vitro models
19.04.2023
In the process of organoid manufacturing, bioprinting technology not only facilitates the creation and maintenance of complex biological 3D shapes and structures, but also allows for standardization and quality control during production.
Fraunhofer-Translationszentrum/Fraunhofer ISC
SAPs4Tissue: human tissue models with customized biomaterials
12.04.2023
In a joint project of the Max Planck Institute for Polymer Research, Mainz, and the Translational Center for Regenerative Therapies at the Fraunhofer Institute for Silicate Research ISC, Würzburg, scientific principles and biomaterials for the standardized production of valid tissue models are to be developed.
Universidad de Barcelona
Microfluidics physics-based device to predict cancer therapy response
06.04.2023
A team of experts has designed a microfluidic device called microfluidic dynamic BH3 profiling (μDBP) that predicts the effectiveness of cancer treatment quickly and automatically.
HZDR/Sandoval Bojorquez
Nanobiosensor developed for detecting SARS-CoV-2
04.04.2023
Infection and immunity status of the population are considered key parameters for handling pandemics. For this purpose, detecting antigens and antibodies is of great importance. The devices currently used for this purpose - what are known as point-of-care (POC) devices- are one option for rapid screening. Their sensitivity, however, needs further improvement.
Gustavo Raskosky/Rice University
Upgraded tumor model optimizes search for cancer therapies
27.03.2023
Rice University researchers developed an upgraded tumor model that houses osteosarcoma cells beside immune cells known as macrophages inside a three-dimensional structure engineered to mimic bone. Using the model, bioengineer Antonios Mikos and collaborators found that the body’s immune response can make tumor cells more resistant to chemotherapy.
DC_Studio
New artificial model validates antibodies ability to reach the brain
03.03.2023
A research group at Uppsala University has developed a simple and effective artificial blood-brain barrier model that can be used to determine how well antibody-based therapies can enter the brain.
imagesourcecurated
Electrodes grown in the brain – paving the way for future therapies for neurological disorders
02.03.2023
The boundaries between biology and technology are becoming blurred. Researchers at Linköping, Lund, and Gothenburg universities in Sweden have successfully grown electrodes in living tissue using the body’s molecules as triggers. The result, published in the journal Science, paves the way for the formation of fully integrated electronic circuits in living organisms.
PeterHermesFurian
"Spleen-on-a-chip" yields insight into sickle cell disease
06.02.2023
With this microfluidic device, researchers modeled how sickled blood cells clog the spleen’s filters, leading to a potentially life-threatening condition.
Together for the newest technology – Highlight tour at the Fraunhofer joint stand
15.11.2022
Several Fraunhofer institutes present their latest technology in the field of medical technology and health at MEDICA 2022. Automation processes, polymers and digital networking are just some of the topics to be found at the stand. We talked to some of the institutes during our highlight tour.
Berthold Steinhilber
Ex vivo obesity research thanks to the adipose-on-chip system
08.07.2022
Ex vivo studies of human obesity without animal testing? The Adipose-on-Chip system offers a solution that allows scientists to gain better insights into various obesity-linked secondary diseases and comorbidities in the future.
Multi-organ chips: Drug research without animal testing at vasQlab
15.05.2019
New active substances that are suitable for drugs are initially tested in animal experiments. However, the results cannot always be transferred to the human organism. At the Karlsruhe Institute of Technology, Prof. Ute Schepers from vasQlab explains how active substances can be tested in human tissue without endangering human health.
Organ-on-a-chip systems: limited validity?
01.02.2019
Organ-on-a-chip systems are technically a great enhancement of medical research because they facilitate testing of active ingredients on cell cultures in the chambers of a plastic chip. This replaces animal testing and improves patient safety. That being said, they are not a true-to-life replication of the human body and can only simulate a few functions and activities.
Organ-on-a-chip – Organs in miniature format
01.02.2019
In vitro processes and animal tests are used to develop new medications and novel therapeutic approaches. However, animal testing raises important ethical concerns. Organ-on-a-chip models promise to be a feasible alternative. In a system the size of a smartphone, organs are connected using artificial circulation.