Antibiotic resistance: technical tricks against pathogens
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Image: A computer that evaluates stool samples using bioinformatic methods; Copyright: Anna Schroll/Leibniz-HKI

Anna Schroll/Leibniz-HKI

Model shows intestinal bacteria influence growth of fungi

22.05.2023

The bacteria present in the intestine provide information about the quantities of fungi of the potentially disease-causing Candida genus.
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Image: Close up of test tubes in a laboratory; Copyright: leungchopan

leungchopan

AI helps create better, simpler hepatitis, COVID-19 tests

11.05.2023

University of Florida scientists have used artificial intelligence tools to simplify a test that works for both hepatitis C and SARS-CoV-2, the virus that causes COVID-19. The simplified test happens in one small test tube in just a few minutes.
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Image: 3D-segmentation of different structures related to an infection with the Ebola virus.; Copyright: Petr Chlanda

Petr Chlanda

Luring the virus into a trap

04.05.2023

Heidelberg researchers describe mechanisms that could help prevent infections with the influenza A and Ebola viruses.
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Image: A Setup to conduct Optical Nanomotion Detection, b Optical image of E. coli bacteria. C. Same field of view as B in false colors; Copyright: Ines Villalba (EPFL)

Ines Villalba (EPFL)

Antibiotic resistance: fast, cheap, and easy test method

02.05.2023

“We have developed a technique in our laboratories that allows us to obtain an antibiogram within 2-4 hours – instead of the current 24 hours for the most common germs and one month for tuberculosis,” says Dr Sandor Kasas at EPFL.
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Image: Daniel Aili, professor at the Department of Physics, man with brown hair and glasses, smiles at the camera; Copyright: Magnus Johansson

Magnus Johansson

Wound dressing reveals infection

26.04.2023

A nanocellulose wound dressing that can reveal early signs of infection without interfering with the healing process has been developed by researchers at Linköping University, Sweden.
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Image: Three women and a man are smiling and looking at their laptops while sitting in a library; Copyright: Uni Tübingen

Uni Tübingen

Targeted computer modelling to accelerate antiviral drug development

31.03.2023

Andreas Dräger from the University of Tübingen is working on a computer-based method that can help to accelerate the time-consuming identification and development of antiviral agents.
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Image: Study co-authors in white coats (from left) Caleb Bashor, Antonios Mikos and Letitia Chim; Copyright: Gustavo Raskosky/Rice University

Gustavo Raskosky/Rice University

Upgraded tumor model optimizes search for cancer therapies

27.03.2023

Rice University researchers developed an upgraded tumor model that houses osteosarcoma cells beside immune cells known as macrophages inside a three-dimensional structure engineered to mimic bone. Using the model, bioengineer Antonios Mikos and collaborators found that the body’s immune response can make tumor cells more resistant to chemotherapy.
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Image: Close-up of a female hand holding the orange ribbon symbolizing the fight against leukemia; Copyright: JoPanwatD

JoPanwatD

AI finds targets for CAR-T cell therapy against acute myeloid leukemia

20.03.2023

Unlike other forms of blood cancer, acute myeloid leukemia (AML) cannot currently be treated with CAR-T cell immunotherapy. The reason is that specific molecular targets with which certain immune cells could specifically target AML cells are lacking, which would permit the immune system to attack cancer.
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Image: Close-up of a scientist wearing protective clothing looking through a microscope; Copyright: ckstockphoto

ckstockphoto

Smart microscopy works out where to take the picture

16.03.2023

Researchers at Lund University in Sweden have now developed a software solution for smart, data-driven microscopy, which makes this possible.
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Image: Microscopic image: Mouse lymph nodes with colored fluorescent markers; Copyright: AG Hoelzel/UKB

AG Hoelzel/UKB

Artificial intelligence to help tumor immunology

09.03.2023

Developing methods to predict the nature of the tumor microenvironment is the goal of researchers from the Clusters of Excellence ImmunoSensation2 and the Hausdorff Center for Mathematics (HCM) led by Prof. Kevin Thurley at the University of Bonn.
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Image: Logo of the EU project miGut-Health, black, violet and green colors on a white background; Copyright: Eurice Office

Eurice Office

Personalised health blueprint to prevent and predict inflammatory bowel disease

07.03.2023

Project led by PMI member Prof. Andre Franke aims to empower people affected by Crohn’s disease and ulcerative colitis by developing interdisciplinary solutions for improved disease prevention and health promotion.
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Image: The photo shows the scanning of a blood sample in a laboratory at CiiM.; Copyright: Karin Kaiser / MHH

Karin Kaiser / MHH

What leads to severe COVID-19 diseases?

01.03.2023

Infection with SARS-CoV-2 leads to severe disease in some people, while others do not get ill or only experience mild disease. But why is this the case? Unfortunately, we do not know exactly. We do know that an overactive innate immune system is causing severe COVID-19 disease, but it is unclear how this is regulated.
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Image: Two men in dark clothes posing in front of the experimental station Alvra of the Swiss X-ray free-electron laser SwissFEL; Copyright: Paul Scherrer Institut/Markus Fischer

Paul Scherrer Institut/Markus Fischer

Using light to switch drugs on and off

27.02.2023

In the ImageTox project, the Helmholtz Institute for Pharmaceutical Research Saarland (HIPS) and the CISPA Helmholtz Center for Information Security are pooling their expertise in the fields of drug discovery and artificial intelligence (AI).
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Image: Researchers at HIPS work with zebrafish larvae to detect potential side effects of new drugs at an early stage; Copyright: Dietze / HIPS

Dietze / HIPS

HIPS and CISPA join forces to make future active ingredients safer

23.02.2023

In the ImageTox project, the Helmholtz Institute for Pharmaceutical Research Saarland (HIPS) and the CISPA Helmholtz Center for Information Security are pooling their expertise in the fields of drug discovery and artificial intelligence (AI).
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Image: Immune cell trafficking in diabetic cataract formation.; Copyright: HAWK

HAWK

Imaging: role of immune cells in early diabetic cataract development

22.02.2023

The team of researchers, led by Prof. Dr. Ali Hafezi-Moghadam, Director of the Molecular Biomarkers Nano-Imaging Laboratory (MBNI), in collaboration with Professor Dr. Christoph Rußmann, Dean of the Health Campus and a Visiting Professor at MBNI, found early signs of damage in the eye before the onset of type 2 diabetes.
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Image: Fluorescence staining of Arlo cells. The image shows the overlay of a staining of cell nuclei (gray) and the tight junction protein 1 (blue); Copyright: HIPS/Boese

HIPS/Boese

New cell model for the human lung

16.02.2023

A team led by Prof Claus-Michael Lehr of the Helmholtz Institute for Pharmaceutical Research Saarland (HIPS) has developed a novel human lung cell line that should enable much more accurate predictions of the behavior of active substances or dosage forms in humans than previous systems.
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Image: A man in a white coat and with safety goggles, Hongji Yan, holds a test tube in his hand and is looking at the camera; Copyright: Vaibhav Srivastava

Vaibhav Srivastava

Mucus-based gel improves bone graft results, promotes healing

14.02.2023

Molecules from mucus can be used to produce synthetic bone graft material and help with the healing of larger bone loss, a new study found.
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Image: A woman with black hair in a white coat sits in a research laboratory and operates a microscope; Copyright: wichayada69

wichayada69

Funding to produce biodegradable antiviral and antibacterial materials

08.02.2023

A new junior research group at Freie Universität Berlin, which will investigate the production of biodegradable antiviral and antibacterial materials, with one of the goals of synthesis being new alternatives to conventional antibiotics, will receive a total budget of more than 1.8 million euros from the German Federal Ministry of Education and Research (BMBF) over the next five years.
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Image: Dr Christoph Schultheiss determines blood values for Long COVID in the research laboratory; Copyright: Universitätsmedizin Halle

Universitätsmedizin Halle

Long COVID: blood values indicate reprogramming of immune cells

26.01.2023

The underlying mechanisms of long COVID are not yet fully understood. Molecular clues to different subgroups of long COVID have now been provided by a research group at University Medicine Halle.
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Image: small empty test tubes with lids in different colors; Copyright: Messe Düsseldorf/C. Tillmann

Messe Düsseldorf/C. Tillmann

RNA technologies make targeted immune activation possible

03.11.2022

MEDICA 2022 is right around the corner, ready to deliver insights into the advancements and innovations in laboratory medicine. One of the key topics of the MEDICA LABMED Forum is RNA technologies and the wide range of applications that involve cell biology. RNA technologies not only enable Covid-19 vaccines but promise an array of treatment options for genetic diseases, in and beyond oncology.
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Image: Doctor and medical assistant at the bedside of a patient who has breathing problems and is wearing an oxygen mask; Copyright: DC_Studio

DC_Studio

Why some people get a more severe COVID-19 progression than others

22.08.2022

A team of scientists from the Berlin Institute of Health at Charité (BIH) together with colleagues from the United Kingdom and Canada have found genes and proteins that contribute to a higher risk of severe COVID-19.
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Image: Person in the laboratory holding cell samples under a microscope; Copyright: MICROGEN@GMAIL.COM

MICROGEN@GMAIL.COM

Molecular markers: predicting the most effective treatment for IBD

09.08.2022

Early effective treatment can help manage this condition and improve the quality of life of patients. A research project aims to identify molecular markers to better assess the chances of success of certain biological therapies and subsequently determine the best individualized treatment plan.
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Image: Two men in white shirs - Kazuki Takahashi, Manabu Tokeshi; Copyright: Manabu Tokeshi

Manabu Tokeshi

SARS-CoV-2: rapid method to quantify antibodies

29.07.2021

Scientists have developed a rapid, highly accurate test to detect antibodies against the spike protein of SARS-CoV-2 in human serum, opening a new avenue for understanding the full extent of the pandemic and evaluating the effectiveness of vaccines.
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Image: Head of a mannequin with transparent face shield and surgical mask; Copyright: Messe Düsseldorf/Achim Wiese

virtual.MEDICA 2020: Experience medicine online

02.11.2020

This year is completely different! Normally, we would offer you an advanced peek into the MEDICA’s halls in Dusseldorf at this point. But due to the corona pandemic, the trade fair takes place online as virtual.MEDICA. We nevertheless took a look at this year’s topics of special interest.
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Image: UV Visual Lift; Copyright: by UVentions

by UVentions

Hygiene: Smart protection against pathogens like the coronavirus

23.03.2020

Germs such as bacteria, viruses or pathogenic fungi can spread from one person to another through direct contact when we shake hands or touch objects. People touch door handles and push elevator buttons in public places and constantly move in and out of spaces. Regular manual high-level disinfection is practically impossible. UVentions GmbH has found an intelligent solution for this problem.
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Image: A half-transparent red piece of tissue in a glass filled with a yellow fluid; Copyright: United Therapeutics

rhCollagen: genetically engineered building block for regenerative medicine

03.02.2020

Collagen is the stuff that holds our bodies together and that houses our cells. In regenerative medicine, it is also the stuff that can be applied to wounds to support healing. However, collagen from animal or human sources has some drawbacks for today’s medicine. This is where rhCollagen from the Israeli company CollPlant comes into play.
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Image: cemented artificial hip endoprostheses; Copyright: panthermedia.net/coddie

Endoprostheses: regaining independence and mobility

01.01.2020

Joints can suddenly or gradually deteriorate and lose their natural strength, whether it’s due to accidents, diseases or simple wear and tear. In some of these cases, implants of artificial joints – endoprostheses - can help. As a joint replacement, they are designed to stay in the body for as long as needed and as such improve the patient’s quality of life and mobility.
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Image: doctor consoles patients before surgery; Copyright: panthermedia.net/luckybusiness

Endoprosthetic surgery: modern and traditional approaches

01.01.2020

Surgery is required if you need an artificial joint. Patients and doctors must select the type of surgery that’s best suited and choose between robot-assisted, traditional or minimally invasive surgical approaches. Post-operative risks should be kept to a minimum, while benefits should outweigh any possible complications.
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Image: Athlete with knee pain; Copyright: panthermedia.net/Wavebreakmedia Itd

Endoprostheses: between possibility and reality

01.01.2020

When natural joints lose their ability to function, they can be completely or partially replaced by artificial joints, also called endoprostheses. Endoprostheses must be of a certain quality, as they should remain in the body as long as possible. In addition to some risks, endoprostheses can also contribute to a mobile and carefree life for young and old.
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Image: Flags are blowing in the wind to the backdrop of a dark evening sky; Copyright: Messe Düsseldorf/ctillmann

Medicine at the pulse of time: Innovations and trends at MEDICA 2019

04.11.2019

Soon, the world's largest trade fair for medical technology will open its doors again: More than 5.000 exhibitors will present their newest products and ideas at MEDICA from 18 to 21 November. You will not only meet well-known companies here, but also lots of young start-ups. Or, you can visit the MEDICA forums and conferences to experience a rich program of lectures and discussions.
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Image: Volker Bruns; Copyright: Fraunhofer ISS

Fraunhofer ISS

AI software: "iSTIX opens your world to the possibilities of digital pathology"

08.10.2019

The healthcare market offers a multitude of microscopes that make cells visible to the human eye. The same applies to AI-based software for image analysis. After taking the microscopic images, scientist are faced with large volumes of scans with usually low resolution. Yet when all aspects merge together, they open up a the world of digital pathology.
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Image: Two petri dishes with different kinds of agar plates on which bacterial cultures are growing; Copyright: panthermedia.net/photographee.eu

Antibiotic resistance: technical tricks against pathogens

01.08.2019

An untreatable infection is a nightmare for physicians and potentially life-threatening to the patient. Unfortunately, more and more pathogens emerge that are resistant to drugs, especially antibiotics. We need to use our drugs smartly and come up with technical solutions as well to prevent our weapons from blunting in the future.
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Image: Sports shoes of an athlete; Copyright: panthermedia.net/ Daxiao_Productions

Sports medicine - performance values in best health

01.07.2019

Those who integrate physical activities into their own lifestyle live healthier and more balanced. But where are the physical limits? Can health status measurements also be carried out on the road? Discover more about how sports medical examinations contribute to maintain performance and minimize health risks in our Topic of the Month.
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Image: Marathon runner; Copyright: panthermedia.net/adamgregor

Sports medicine – keep moving to stay healthy

01.07.2019

Physical activity plays a big role in today's society. Whether you are an amateur or professional athlete – incorporating exercise into your life positively impacts your mental and physical health. Ideally, sport should be fun, pressure-free and not overburden you. But can you measure individual performance and align it with sports?
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Image: Preview picture of video

Functional Imaging: The puls of modern oncology

17.06.2019

Medical imaging techniques have developed considerably in recent decades. In addition to morphological imaging techniques more and more functional imaging techniques are used in oncology that can continously record the functions of specific organs locally and regionally in real time. These are groundbreaking for diagnostics, therapies and preoperative preparations.
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