"One problem is that confined areas exposed to noxious compounds, such as alcohol, can have harmful effects on the infants," explains Clinical Assistant Professor Satoshi Fujiyama, senior author of the study. But to date, no studies had investigated the level of alcohol exposure in infants in incubators.
To determine the amount of alcohol that evaporates from alcohol-based disinfectants that are systematically absorbed by premature infants, the researchers measured the blood alcohol concentration in premature infants and in the air of neonatal incubators. The researchers also introduced a new alcohol-based disinfectant practice (ABD-PRAC) that reduced the evaporation of alcohol from ABDs inside the incubators without affecting infection control and determined its association with decreasing alcohol exposure in premature infants less than 34 weeks old. The changes in alcohol concentration in the infants' blood and in the air of the incubators were then measured.
Results showed that alcohol was continuously detected in the blood samples taken from the infants, and its concentration was primarily associated with the evaporated alcohol from the ABDs in the incubators. The key factors affecting alcohol absorption in premature infants included their airways and immature skin. Hence, it was concluded that decreasing the alcohol concentration inside the incubators through ABD-PRAC is a simple way of reducing the amount of evaporated alcohol.
"Our study showed that reducing the exposure of infants to evaporated alcohol can be an easy task," says Professor Hidetoshi Takada, senior author.
This research has identified the risks to premature infants posed by certain measures, which were intended to keep them safe. It has also shown how easily these risks can be reduced by a change in practice within the neonatal infant care units. Adoption of these simple practices in NICUs will reduce the risks to premature babies associated with their care in hospital, ensuring that the optimal disinfectant used is based on its efficacy and safety.
MEDICA-tradefair.com; Source: University of Tsukuba
