The WPEDs are designed to conform to the irregular shapes and depths of chronic wounds, ensuring that the electric field effectively targets the wound from the periphery to the center. This is crucial for directing the electric field to stimulate healing across the entire wound surface.
This ability to conform is critical, because we want the electric field to be directed from the periphery of the wound toward the wound’s center," explains Rajaram Kaveti, co-first author and post-doctoral researcher at NC State.
In experiments conducted on diabetic mice, a commonly used model for human wound healing, the researchers found that the WPEDs significantly accelerated wound closure, promoted the formation of new blood vessels, and reduced inflammation. These effects collectively improved the overall healing process.