leungchopan
AI helps create better, simpler hepatitis, COVID-19 tests
11.05.2023
University of Florida scientists have used artificial intelligence tools to simplify a test that works for both hepatitis C and SARS-CoV-2, the virus that causes COVID-19. The simplified test happens in one small test tube in just a few minutes.
Messe Düsseldorf
With stem cell model on the trail of congenital diaphragmatic hernia
09.05.2023
Researchers have designed a new stem cell model to study congenital diaphragmatic hernia in newborns with underdeveloped lungs. They were able to isolate stem cells from the fluid that is suctioned from the baby’s lungs and normally gets discarded and use them as a foundation for the model.
Universität des Saarlandes/Oliver Dietze
Exploring the molecular mechanisms of ageing
09.05.2023
A team led by bioinformatics experts Andreas Keller and Fabian Kern from Saarland University together with researchers at Stanford University have gained new insights into manifestations of ageing at the molecular level.
Okrasyuk
Map of spinal cord formation gives new knowledge on diseases of the nervous system
03.05.2023
Researchers at Karolinska Institutet in Sweden have mapped how cells in the human spinal cord are formed in the embryo and what genes control the process.
Agnes Toth-Petroczy, Nature Communications
New tool facilitates clinical interpretation of genetic information
27.04.2023
Max Planck and Harvard research teams develop DeMAG, a new method shared as an open-source web server (demag.org) to help interpret mutations in disease genes and improve clinical decision-making.
Daniel Kokotek
New method makes rare cell types visible
13.04.2023
In cooperation with Helmholtz Munich, Professor Matthias Meier from the Centre for Biotechnology and Biomedicine at Leipzig University and his research group have developed a new, effective and comparatively inexpensive method to make rare cell types, cell communication types and disease patterns visible in tissue.
Fraunhofer IPK / Larissa Klassen
New technologies for producing mRNA-based pharmaceuticals
24.03.2023
Together with partners from science and industry, Fraunhofer IPK is researching how mRNA therapeutics and other medication can be better produced and more effectively applied.
Karin Kaiser/MHH.
Better care for pregnant women with precancerous cervical cancer
23.03.2023
Preliminary stages of cervical cancer occur mainly in women between 25 and 35 years of age. The main risk factor for developing cervical cancer is the human papillomavirus (HPV). Surgery is the treatment of choice.
Karin Kaiser / MHH
What leads to severe COVID-19 diseases?
01.03.2023
Infection with SARS-CoV-2 leads to severe disease in some people, while others do not get ill or only experience mild disease. But why is this the case? Unfortunately, we do not know exactly. We do know that an overactive innate immune system is causing severe COVID-19 disease, but it is unclear how this is regulated.
iLexx
The architecture of shattered genomes
27.01.2023
Hunting for disease clues in the dark matter of our DNA. Scientists have reconstructed the chromosomes of patients with an extremely high number of aberrations in their genome that could alter the expression of nearby genes and potentially cause disease. Their results were published in Nature Communications in October 2022.
Karin Kaiser / MHH, Freepik.com
MHH leads EU large-scale project for personalized cancer care
26.01.2023
CAN.HEAL aims to expand the available innovations in cancer prevention, diagnosis and treatment in the Member States in order to improve care for all patients in the EU. The project focuses on measures of personalized medicine. Genomics is an important cornerstone for this.
manjurulhaque
Analyzing disease progression and cell processes with TIGER: in vivo and non-invasively
18.01.2023
Researchers at the Helmholtz Institute for RNA-based Infection Research (HIRI) and the Julius-Maximilians-Universität (JMU) in Würzburg have developed a technology they call TIGER. It allows complex processes in individual cells to be deciphered in vivo by recording past RNA transcripts.
westend61
Big Data: Helper and game changer in laboratory medicine and genetics
01.08.2022
Big data, the use of large volumes of data in diagnostics and research, is giving medical science a powerful boost. Especially in laboratory medicine, big data can provide unprecedented support as doctors must consider a multitude of data and parameters to facilitate accurate medical decision-making.
LipiTUM
MoSBi: Algorithm identifies disease subtypes
01.08.2022
Doctors have always used symptoms, imaging, and laboratory data to define and diagnose diseases, but at times it is simply not enough: while patients may have the same illness, it may exhibit different changes at the molecular level. A team from the Technical University of Munich has developed the so-called MoSBi algorithm and makes it available to researchers to identify molecular differences.
ktsimage
Big Data in genetics: reaching diagnosis through heaps of data
01.08.2022
Most laboratory tests only produce small amounts of data that are already sufficient for successful diagnosis. It becomes more difficult with genetic questions: whether it is about a genetic disease or the properties of tumors, there are large amounts of data that must be considered. Both research and medicine need help to identify the connections and patterns in the data to find a diagnosis.
Mark Stone/University of Washington
Fast and cheap test can detect COVID-19 virus' genome without need for PCR
25.01.2022
Researchers at the University of Washington have developed a new test for COVID-19 that combines the speed of over-the-counter antigen tests with the accuracy of PCR tests that are processed in medical labs and hospitals.
LampSeq – Scalable and cost-effective mass test
15.10.2021
Vaccinations and tests once again enable safe gatherings during the Corona pandemic. But unfortunately, existing test technologies are not suitable for every situation: A lot of time is lost for example due to testing at schools and the workplace. Now the University Hospital Bonn has developed a new kind of test which has numerous advantages over existing technologies.
Manabu Tokeshi
SARS-CoV-2: rapid method to quantify antibodies
29.07.2021
Scientists have developed a rapid, highly accurate test to detect antibodies against the spike protein of SARS-CoV-2 in human serum, opening a new avenue for understanding the full extent of the pandemic and evaluating the effectiveness of vaccines.
Point-of-care tests: rapid diagnosis in emergency situations
01.06.2021
In emergency medicine, a faster diagnosis leads to a faster treatment of the patient. Point-of-care test solutions can provide immediate on-site insights into the patient’s condition. COVID-19 adds another dimension: the devices can provide a level of security and safety – one that goes beyond intensive care.
rhCollagen: genetically engineered building block for regenerative medicine
03.02.2020
Collagen is the stuff that holds our bodies together and that houses our cells. In regenerative medicine, it is also the stuff that can be applied to wounds to support healing. However, collagen from animal or human sources has some drawbacks for today’s medicine. This is where rhCollagen from the Israeli company CollPlant comes into play.
Last-resort antibiotics: "We can identify carbapenemases within half an hour"
01.08.2019
Antibiotic resistance is modern medicine's greatest challenge. Some bacteria only respond to a handful of antibiotics, prompting hospitals to spend a lot of time finding an effective drug. That’s why it is critical for physicians to rapidly identify antibiotic resistance to avoid ineffective treatments.
Multi-organ chips: Drug research without animal testing at vasQlab
15.05.2019
New active substances that are suitable for drugs are initially tested in animal experiments. However, the results cannot always be transferred to the human organism. At the Karlsruhe Institute of Technology, Prof. Ute Schepers from vasQlab explains how active substances can be tested in human tissue without endangering human health.