27/03/2023Rice University researchers developed an upgraded tumor model that houses osteosarcoma cells beside immune cells known as macrophages inside a three-dimensional structure engineered to mimic bone. Using the model, bioengineer Antonios Mikos and collaborators found that the body’s immune response can make tumor cells more resistant to chemotherapy.
14/03/2023The technological basis is a proprietary platform technology for the discovery of drugs that target cancer-causing protein-protein interactions (PPIs).
09/03/2023Developing methods to predict the nature of the tumor microenvironment is the goal of researchers from the Clusters of Excellence ImmunoSensation2 and the Hausdorff Center for Mathematics (HCM) led by Prof. Kevin Thurley at the University of Bonn.
08/03/2023Using artificial intelligence (AI) methods, researchers led by Professor Dr Alexander Schönhuth from Bielefeld University’s Faculty of Technology have succeeded in recording and deciphering the genotype profiles of 3,000 ALS patients and thus learning more about the development of the disease.
07/03/2023Project led by PMI member Prof. Andre Franke aims to empower people affected by Crohn’s disease and ulcerative colitis by developing interdisciplinary solutions for improved disease prevention and health promotion.
01/03/2023Obesity and a sedentary lifestyle contribute to an increasing number of people developing fatty liver disease. There is a need for early detection of individuals at risk of developing sequelae.
09/02/2023Miniature assistants can act as a stimulus in cases of tinnitus or digestive tract disorders or help a person’s hand to regain the ability to grip.
01/02/2023International research groups led by Prof. Dr. Aldo Faisal, Professor of Digital Health at the University of Bayreuth, have developed a novel set of tools for diagnosing and monitoring neurological diseases based on body-worn sensors (wearables) and artificial intelligence.
26/01/2023CAN.HEAL aims to expand the available innovations in cancer prevention, diagnosis and treatment in the Member States in order to improve care for all patients in the EU. The project focuses on measures of personalized medicine. Genomics is an important cornerstone for this.
19/01/2023A pioneering phase II clinical study on tri-modality therapy (START-FIT), conducted by the Department of Surgery and Department of Clinical Oncology, School of Clinical Medicine, LKS Faculty of Medicine of the University of Hong Kong (HKUMed), has found that nearly 50% of patients with inoperable locally advanced liver cancer, can be cured through such an innovative approach.
17/01/2023For the first time, a study conducted by a research group at the Comprehensive Cancer Centre Vienna of MedUni Vienna and Vienna General Hospital using data from the multicentre EMBRACE-I trial demonstrated the superiority of a targeted approach in brachytherapy.
09/01/2023The "digital patient" is a model that encompasses everything from patients who use VR headsets to meet with their doctor in the metaverse to those who use smart technologies to find a possible diagnosis.
02/11/2022Watching your diet based on various health issues can sometimes be tiring. To make the process easier and help patients to monitor their intake, the start-up Doinglab developed an artificial intelligence technology that can recognize and understand food. FoodLens provides detailed information about the food with just a picture.
18/10/2022To treat musculoskeletal disorders physical therapy is often essential to help patients suffering from chronic pain. But following a patient’s progress in physical therapy can be difficult without a matching tool. To improve rehabilitation and further personalize treatment, DyCare developed a digital rehabilitation platform called ReHub.
05/10/2022In the MED²ICIN lead project, a digital patient model for chronically ill persons has been developed. A particularly clear, web-based dashboard shows, among other things, the course of the disease, medication responses and recommendations for action. In addition, the data can be compared with a large pool of data from other patients.
22/09/2022Breast cancer diagnosis usually includes invasive testing with tissue biopsies. The samples have to be extracted from the cancerous tissue or cells. To make the process easier on the patients, the project LIBIMEDOTS is currently developing a different approach with liquid biopsy technology.
01/08/2022Most laboratory tests only produce small amounts of data that are already sufficient for successful diagnosis. It becomes more difficult with genetic questions: whether it is about a genetic disease or the properties of tumors, there are large amounts of data that must be considered. Both research and medicine need help to identify the connections and patterns in the data to find a diagnosis.
01/08/2022Big data, the use of large volumes of data in diagnostics and research, is giving medical science a powerful boost. Especially in laboratory medicine, big data can provide unprecedented support as doctors must consider a multitude of data and parameters to facilitate accurate medical decision-making.
22/07/2022Chest pain, shortness of breath, a brief loss of consciousness – warning signs that suggest a heart attack. But it might also be Takotsubo syndrome, also known as stress cardiomyopathy or broken heart syndrome with symptoms that resemble a heart attack. Yet it is of utmost importance to differentiate between the two conditions to initiate the right treatment.
08/07/2022Ex vivo studies of human obesity without animal testing? The Adipose-on-Chip system offers a solution that allows scientists to gain better insights into various obesity-linked secondary diseases and comorbidities in the future.
22/06/2022Many diseases can be treated successfully if they are diagnosed early. Research into a “digital (electronic) nose” is one promising development to facilitate early detection and diagnosis. That’s because body odors and their molecular composition are an early indicator of various diseases that often remain undetected in the early stages.
08/06/2022We are nowadays already able to weave implants out of artificial fibers that can replace tissue or heal injuries. Different materials like polymers or nitinol are used to create flexible shapes. But the materials and their uses can still be improved.
23/05/2022People around the world suffer from sleep disorders. Some conditions like sleep apnea or chronic respiratory disease can lead to serious health problems. Patients require medical long-term monitoring, but it’s currently not an easy feat. Graduates of ETH Zurich and the University of St. Gallen plan to change that and developed Sleepiz.
10/05/2022Following an injury or surgery, orthotics are key components of the recovery and rehabilitation process. The University spin-off 3Digity designs 3D-printed customized finger orthoses to foster rehabilitation as custom orthotics can drastically speed up the recovery process.
22/04/2022We all make mistakes from time to time or forget to do things. But people with diabetes can have serious health problems if they miscalculate or inject the wrong insulin dose. A research team from the Dresden University of Technology (TU Dresden) and a startup from Leipzig aim to make living with diabetes easier.
05/04/2022The treatment of chronic and acute pain phases centers on the patient’s pain profile. The treatment strategies must be flexible to facilitate customized adjustments. The AI-powered pain treatment solution by medicalmotion offers support and makes individualized exercise recommendations to manage the individual needs of pain patients with neuromusculoskeletal disorders.
02/11/2021Back problems are generally regarded as a widespread disease with many sufferers struggling with pain. A team of researchers from TU Kaiserslautern, the University Medical Centre in Mainz and several companies is working on a method that will enable more efficient monitoring of malpositions and strains on the back. Artificial intelligence methods are also being used.
01/09/2021Wearables are increasingly being used in sports medicine, for example, to prevent injuries or to provide users individually with real-time data about their fitness and health. By analyzing this data, risks for sports injuries can be identified early and training can be customized to the user's needs and goals.
15/03/2021Heart surgery is difficult even for experienced surgeons and therapeutical success is not always certain. Physicians need to rely on their experience when choosing and planning the correct intervention. A computer model could help them in the future: The digital twin heart could be fed with patient data and then simulate whether an intervention will be successful.
27/01/2021Drug research and artificial skin replacement - these are the areas in which tissue engineering and bioprinting are already used today. What else could be possible in the future? We asked Dr. Nadine Nottrodt from Fraunhofer ILT and Prof. Sabine Neuß-Stein from RWTH Aachen University Hospital!
11/01/2021Today, managing one's own chronic disease is hardly possible without digital helpers – not least because of the corona pandemic. People with asthma also benefit from apps and wearables. They help patients connect better with doctors and better understand their own disease. Our Topic of the Month looks at why this is so important and what the digital services can do.
01/12/2020It aims at the production of test systems for drug research and gives patients on the waiting lists for donor organs hope: bioprinting. Thereby biologically functional tissues are printed. But how does that actually work? What are the different bioprinting methods? And can entire organs be printed with it? These and other questions are examined in our Topic of the Month.
22/05/2020Athletes not only have to be fit and stay in shape, but they also have to achieve peak performance, especially when they get ready for athletic events. Optimized and individualized performance training requires data from external laboratories and institutes. The [i/med] Sports platform from DORNER Health IT Solutions provides a complete workflow − from anamnesis to diagnostic report.
19/03/2020Regenerative medicine often relies on implants and materials that support healing in our body. Collagen has a special significance here. It is compatible to the body and offers an excellent environment for the growing of new cells. In our video, we took a look on where collagen and collagen products for medicine come from.
03/02/2020Regenerative medicine aims to repair the human body after injuries, accidents or major cancer surgery. Unfortunately, we are still not at a stage where this process can achieve optimal results for every conceivable situation. Having said that, various new methods are on the cusp of breakthrough.
03/02/2020Regenerative medicine aims to replace damage in the body with functional tissue and restore normal function. The first defense for large defects are implants made of hydrogels, designed to promote cell growth. They need their own blood supply, which is a problem when it comes to larger implants because you cannot regulate where and how the blood vessels grow - until now.
03/02/2020Severe wounds heal slowly and leave scars. This is why we have been using regenerative therapies for some time now to accelerate and improve healing. They also help to avoid permanent damage. Still, complex applications like replacing organs or limbs will rather remain vision than become reality for a long time.
14/11/2019Acute respiratory distress syndrome (ARDS) is a life-threatening illness in which the lungs are severely damaged. The condition always requires intensive medical care through mechanical ventilation. But not all lungs are the same. To ensure a personalized treatment that is adapted to the individual patient’s lung volume and condition, Ebenbuild relies on digital twins.
08/11/2019If physicians suspect an acute myocardial infarction, they first order an ECG. This test is very established and allows cardiologists to quickly diagnose acute heart attacks – though the test does not detect less common heart attack symptoms. So far, those patients had to wait up to twelve hours before a heart attack could be accurately diagnosed or ruled out. But things are about the change.
22/10/2019Professor Jarek Krajewski sat down for a MEDICA interview and delivered a detailed description of the Sports Hub project. It highlights how big data and AI transform the world of sports medicine. The project delivers new insights and provides a versatile database.
08/10/2019The healthcare market offers a multitude of microscopes that make cells visible to the human eye. The same applies to AI-based software for image analysis. After taking the microscopic images, scientist are faced with large volumes of scans with usually low resolution. Yet when all aspects merge together, they open up a the world of digital pathology.
23/09/2019For patients waiting for donor organs, every day can mean the difference between life and death. Making things even more complicated is the fact that not every organ is a compatible match with the patient. It would mean enormous progress if we could grow organs from the patient's own cells in the lab. That's why patients with heart disease place big hope in tissue engineering.
22/08/2019The German Medical Award will take place on November 18, 2019, as part of the MEDICA trade fair in Düsseldorf. The ceremony emphasizes the commitment to excellence in cutting-edge care for patients. Doctors, clinical centers and companies in the medical and healthcare industry can demonstrate their achievements in medicine and management in hopes of receiving the coveted award.
20/08/2019Movement, strength and coordination - after injuries as well as in healthy athletes, these three components must be intact for movements to run smoothly. At the Beta Klinik in Bonn, Dr. Markus Klingenberg, a specialist in orthopaedics, trauma surgery and sports medicine, offers neuromuscular training with a playful character that can be adapted to the patient's needs.
16/08/2019In medicine, robots are already taking over tasks that only a few years ago were exclusively in human hands. Especially in the field of rehabilitation, they will play a major role in the future. In the "RoSylerNT" project of the German Sport University Cologne, a robot arm from KUKA is being used here for training purposes. Find out why a robot is the right training partner!
17/06/2019Medical imaging techniques have developed considerably in recent decades. In addition to morphological imaging techniques more and more functional imaging techniques are used in oncology that can continously record the functions of specific organs locally and regionally in real time. These are groundbreaking for diagnostics, therapies and preoperative preparations.
04/06/2019Tendinitis, myofascial pain syndromes or fractures - shock wave therapy is a noninvasive method with no side effects that promises relief. The intensity of the shock waves can be customized to meet patients’ needs and yields fast positive results. In addition to advising doctor’s offices, clinical facilities, and universities, Kröner Medizintechnik GmbH also offers treatment, support, and care.
15/05/2019New active substances that are suitable for drugs are initially tested in animal experiments. However, the results cannot always be transferred to the human organism. At the Karlsruhe Institute of Technology, Prof. Ute Schepers from vasQlab explains how active substances can be tested in human tissue without endangering human health.
01/04/2019Our brain is the command center of our body. This is where all information and impressions are collected and converted into responses and movements. Modern imaging techniques offer physicians and researchers unique insights into the actions of the human central nervous system. The functional imaging technique allows them to watch our brain in action.
01/04/2019A surgery already begins before the patient is lying on the operating table – namely with the planning. For example, if brain surgery is imminent, the brain must first be mapped. This makes the activity level of certain brain areas visible. Functional magnetic resonance imaging makes this possible.
01/03/2019Coughing, airway obstruction, difficulty breathing: Chronic obstructive pulmonary disease (COPD) is an umbrella term used to describe progressive and currently incurable lung diseases. The innovative solutions of Philips Respironics help patients to manage each stage of the disease and their medication intake, train the respiratory system and provide respiratory support.
01/03/2019COPD affects more than 200 million people in the world. Those affected by this chronic pulmonary disease are often slow to notice the symptoms and get a medical diagnosis. This results in secondary complications and high medical costs. That's why an early diagnosis, comprehensive treatment, and frequent monitoring are very important. Various devices and tools support this all-round care.
01/02/2019In vitro processes and animal tests are used to develop new medications and novel therapeutic approaches. However, animal testing raises important ethical concerns. Organ-on-a-chip models promise to be a feasible alternative. In a system the size of a smartphone, organs are connected using artificial circulation.
01/02/2019The liver, nervous tissue or the intestines: all are important human organs that have in the past been tested for their function and compatibility using animal or in vitro test methods. In recent years, TissUse GmbH, a spin-off of the Technical University of Berlin (TU Berlin), has launched multi-organ chip platforms. But that’s not all.
08/01/2019Parkinson's disease is a progressive nervous system disorder that primarily affects movement of patients and makes their everyday lives very challenging. It also makes regular doctor appointments and treatment sessions necessary. "TelePark" - a project that collects different movement-related parameters using sensors and apps is designed to improve the quality of life for Parkinson’s patients.
02/01/2019Diabetes mellitus or simply diabetes has become very common and is often described as a lifestyle disease. More and more people are suffering from this chronic metabolic disorder. Next to established diagnostic procedures, digital retinal screening has shown to be successful - a promising technique that will also play an important role in the diagnosis of other diseases in the future.