Laboratory technology and diagnostic tests -- MEDICA - World Forum for Medicine

News from the editors of MEDICA-tradefair.com

Neurons act as pulse generators
An international team of brain researchers achieved a breakthrough in uncovering a switch-like mechanism that flips the brain between two motivational states in larval zebrafish, a model organism in neuroscience. How the brain switches between states is a central mystery in neuroscience.
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DNA: first images of an 'upgraded' CRISPR tool
Columbia scientists have captured the first images of a new gene editing tool that could improve upon existing CRISPR-based tools. The team developed the tool, called INTEGRATE, after discovering a unique "jumping gene" in Vibrio cholerae bacteria that could insert large genetic payloads in the genome without introducing DNA breaks.
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Infectious Immunology: newly discovered protein gives signal
Researchers at the University of Zurich have discovered a protein that enables adenoviruses to infect human cells. The Mib1 protein gives the virus the signal to uncoat the DNA and release it into the nucleus. Blocking this protein could therefore help people with weakened immune systems to fight dangerous viruses.
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Tissue Engineering: tracking lab-grown tissue with light
New proof-of-concept photonic pH sensor could advance studies of tissue regeneration. Someday, doctors would like to grow limbs and other body tissue for soldiers who have lost arms in battle, children who need a new heart or liver, and many other people with critical needs.
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Machine learning: to measure inflammation process
UNC School of Medicine researchers created an artificial intelligence tool to measure NETosis, an inflammatory process where white blood cells trap invaders; this work will help scientists find ways to stop or promote NETosis in disease states
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Tissue Engeneering: new in-vitro 3D neural tissue model
Researchers at the University of Illinois at Urbana-Champaign have successfully used stem cells to engineer living biohybrid nerve tissue to develop 3D models of neural networks with the hopes of gaining a better understanding of how the brain and these networks work.
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Drug information system: shows how cancer cells react to drugs
A new technique overcomes several limitations of typical high-throughput chemical screens conducted on cell samples. Such screens are commonly used to try to discover new cancer drugs, and in many other biomedical applications.
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eHealth: Records could improve pediatric sepsis surveillance
Sepsis is a major public health problem, contributing to substantial disability, death, and healthcare costs in the United States among both adults and children. Though sepsis is the focus of worldwide prevention and quality improvement efforts, tracking sepsis rates and outcomes is challenging because a definitive diagnostic test does not yet exist.
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Diagnostics: New home urine test for prostate cancer
A simple urine test under development for prostate cancer detection can now use urine samples collected at home - according to new research from University of East Anglia and the Norfolk and Norwich University Hospital.
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AI: startup developing tool for tuberculosis detection
Diascopic LLC, a Cleveland-based medical research company that develops diagnostic technology, will use a highly competitive federal grant to develop and apply new artificial intelligence (AI) and digital pathology tools for detecting tuberculosis (TB).
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Tissue Engineering: new ways to avoid animal testing
Around 60 international experts met on November 7 at the Fraunhofer Institute for Silicate Research ISC in Wuerzburg to report on the state of the art in the field of 3D tissue models and prevention of animal experiments in the development of pharmaceuticals and medical devices.
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Cells: blocking metastasis-promoting enzyme
In a breakthrough with important implications for the future of immunotherapy for breast cancer, UC San Francisco scientists have found that blocking the activity of a single enzyme can prevent a common type of breast cancer from spreading to distant organs.
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Diabetes: women most affected by vascular complications
Women are most affected by the vascular complications of diabetes - a situation likely to escalate in the coming decades, reports a paper published on World Diabetes Day in the European Journal of Preventive Cardiology, a journal of the European Society of Cardiology (ESC). Cardiovascular disease occurs 15 years earlier in patients with diabetes and is their main cause of morbidity and mortality.
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Biosensor: technology created for stem cells
A Rutgers-led team has created better biosensor technology that may help lead to safe stem cell therapies for treating Alzheimer's and Parkinson's diseases and other neurological disorders.
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Cells: oxygen-starved tumor cells promoting cancer spread
Using cells from human breast cancers and mouse breast cancer models, researchers at the Johns Hopkins Kimmel Cancer Center say they have significant new evidence that tumor cells exposed to low-oxygen conditions have an advantage when it comes to invading and surviving in the bloodstream.
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Immunology: why beta-blockers cause skin inflammation
Beta-blockers are often used to treat high blood pressure and other cardiovascular diseases. However, in some patients they can trigger or exacerbate psoriasis, an inflammatory skin disease. Scientists at the University of Bonn and Freie Universität Berlin have now found a possible cause for this. Their results have been published in the renowned journal "Autophagy".
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AI: revealing the nature of RNA-protein interactions
A new computational tool developed by KAUST scientists uses artificial intelligence (AI) to infer the RNA-binding properties of proteins. The software, called NucleicNet, outperforms other algorithmic models of its kind and provides additional biological insights that could aid in drug design and development.
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Regenerative medicine: material for cell immune response
Scientists of Tomsk Polytechnic University jointly with the University of Montana (USA) proposed a new promising material for regenerative medicine for recovery of damaged tissues and blood vessels.
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Vaccines: super-antibody strategy
New influenza vaccines are required every autumn, because the viruses constantly change the components to which our immune protection responds. Medical research is focusing on universal vaccines that target more stable parts of the viruses. This new generation of broadly neutralising antibodies is particularly important for controlling life-threatening viral infections.
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Biosensor: made from a dangerous toxin
Some types of bacteria have the ability to punch holes into other cells and kill them. They do this by releasing specialized proteins called "pore-forming toxins" (PFTs) that latch onto the cell's membrane and form a tube-like channel that goes through it. This hole across the membrane is called a pore. Punctured by multiple PFTs, the target cell self-destructs.
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Brain mapping: unraveling the dense networks
The methods to analyze neuronal networks sparsely have been available for decades, the dense mapping of neuronal circuits is a major scientific challenge. Researchers from the MPI for Brain Research have now succeeded in the dense connectomic mapping of brain tissue from the cerebral cortex, and quantify the possible imprint of learning in the circuit.
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Cells: toxin, trauma, therapy?
The department of Prof. Tanja Weil at the Max Planck Institute for Polymer Research has, in cooperation with the group of Prof. Holger Barth from the Institute of Pharmacology and Toxicology at the Ulm University, shown in initial laboratory tests that they are able to specifically modulate processes in human white blood cells in vitro.
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Cells: gut health influences brain health
Over the last two decades, scientists have observed a clear link between autoimmune disorders and a variety of psychiatric conditions. For example, people with autoimmune disorders such as inflammatory bowel disease (IBD), psoriasis and multiple sclerosis may also have depleted gut microbiota and experience anxiety, depression and mood disorders.
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Implant: 3D printing, bioinks create blood vessels
A biomimetic blood vessel was fabricated using a modified 3D cell printing technique and bioinks, which were formulated from smooth muscle cells from a human aorta and endothelial cells from an umbilical vein.
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Point-of-care diagnostic: detecting preterm birth
A new study provides a first step toward the development of an inexpensive point-of-care diagnostic test to assess the presence of known risk factors for preterm birth in resource-poor areas. The study found that measuring levels of TIMP-1 and D-lactic acid in vaginal secretions may be a non-invasive, cost-effective way to assess the risk for preterm birth.
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News from the exhibitors of MEDICA and COMPAMED

Avery Dennison Medical Introduces Eight Adhesive Materials, Wound Care Solutions at Medica 2019
DÜSSELDORF, GERMANY – 18 November 2019 – Avery Dennison Medical is launching eight new products at the 2019 Medica International Trade Fair, which begins today and runs through November 21 at the...
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Canada at MEDICA, Düsseldorf (November 18 - 21, 2019)
Biggest Canadian Participation Ever MEDICA – the leading international medical tradeshow – has been attracting generations of Canadian visitors and exhibitors. This year, 59 Canadian medical...
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Dunn promotes a variety of medical tubing solutions at Compamed
Wayne, Pa. (October 25, 2019) — Dunn Industries, a Tekni-Plex business unit, will exhibit the latest medical tubing innovations at Compamed (Hall 8A / F12), Messe Dusseldorf, November 18-21.
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Natvar discusses innovative microextrusion, silicone medical tubing at Medica
Wayne, Pa. (October 23, 2019) — Natvar, a Tekni-Plex business unit, will exhibit the latest medical tubing innovations at MEDICA (Hall 6 / H30), Messe Dusseldorf, November 18-21. Microextrusion...
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Production of central venous catheters (CVC) from special urethane material
Optimized design of central venous catheters reduces risk of complications In the U.S., more than 5 million central venous catheters (CVCs) are inserted every year, which corresponds to 15 million...
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High Airflow Foam (HAF)
Woodbridge INOAC Technical Products is pleased to introduce our newest contribution to the foam market, High Airflow Foam (HAF). With approximately 20 times greater permeability than conventional...
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Ethylene Oxide Sterilization Solutions: reliable and safe
RSD will be this year at MEDICA trade fair, in Dusseldorf, from November 18th to 21st. For us, it is a good moment to show our EO Sterilization solutions , based on a turnkey proposals and...
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Bionix Development Corporation is a quality driven, service oriented multi-national company committed to acquiring, developing, manufacturing and marketing innovative medical products that help people
Bionix Development Corporation – Going Beyond   Since our founding in 1984, Bionix Development Corporation has been focused on Going Beyond. Going Beyond means more than simply making useful...
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Pioneering UK pressure mattress solutions to be showcased at MEDICA 2019 (Hall 16, Stand KI7-6)
A UK company, who specialises in the development and manufacture of ‘zero pressure’ technology will be at MEDICA to showcase their full range of pioneering mattress solutions. Over the last...
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High Frequency Plastic Welding services for Healthcare Industry showcased at MEDICA 2019
Speed Plastics, a specialist in high frequency welding, will once again be at MEDICA 2019 to showcase the range of bespoke engineering services they offer healthcare companies. Speed Plastics offers a...
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New Geeplus Pinch Valves Suit a Wide Range of Applications
Beckenham, United Kingdom  -In response to the growing demand for small-size low-power control components, the new range of pinch valves will suit a wide variety of applications calling for...
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New Bearing Race Design Launches Geeplus Voice Coil Motor Life Cycle to More Than 100 Million Cycles
Beckenham, United Kingdom  – In order to provide even smoother and considerably longer operation of their VM38 voice coil motor, Geeplus has developed a new version which incorporates redesigned...
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New Suture Technology May Reduce Tissue Strangulation
Teleflex Medical OEM, a global leader in specialized sutures, braids, and fibers, announces an innovative suture technology: Force Fiber Fusion® Suture. This “two-in- one” construct transitions from...
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Raumedic joins Medical Valley EMN e.V.
Helmbrechts/Erlangen  – The medical technology company Raumedic has become a member of the northern Bavarian medical cluster Medical Valley EMN e.V. More than 200 key players in the Nuremberg...
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Video impressions on laboratory technologies

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