Laboratory equipment / diagnostic tests -- MEDICA - World Forum for Medicine

Image: Bispecific antibody on SARS-CoV-2; Copyright: Università della Svizzera italiana

Double antibody protects from SARS-CoV-2

27/01/2021

The Institute for Research in Biomedicine (IRB; Bellinzona, Switzerland), affiliated to the Università della Svizzera italiana (USI) developed a second-generation 'double antibody' that protects from SARS-CoV-2, the virus causing COVID-19, and all its tested variants. It also prevents the virus from mutating to resist the therapy.
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Image: Preview picture of video

Tissue Engineering and Bioprinting – From artificial heart valves and printed humans

27/01/2021

Drug research and artificial skin replacement - these are the areas in which tissue engineering and bioprinting are already used today. What else could be possible in the future? We asked Dr. Nadine Nottrodt from Fraunhofer ILT and Prof. Sabine Neuß-Stein from RWTH Aachen University Hospital!
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Image: SARS-CoV-2; Copyright: Arek Socha from Pixabay

Fighting respiratory virus outbreaks through sensor-based rapid detection

25/01/2021

Viral respiratory diseases are easily transmissible and can spread rapidly across the globe, causing significant damage. The ongoing covid-19 pandemic is a testament to this. In the past too, other viruses have caused massive respiratory disease outbreaks: for example, a subtype of the influenza virus, the type A H1N1 virus, was responsible for the Spanish flu and the Swine flu outbreaks.
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Image: connection between nerve cells; Copyright: Kristian Herrera and authors

Signaling Strength between nerve cells depends on size of connections

22/01/2021

The neocortex is the part of the brain that humans use to process sensory impressions, store memories, give instructions to the muscles, and plan for the future. These computational processes are possible because each nerve cell is a highly complex miniature computer that communicates with around 10,000 other neurons. This communication happens via special connections called synapses.
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Image: testing urine samples using ultra-high-sensitive smart biosensors; Copyright: Korea Institute of Science and Technology (KIST)

Cancer diagnosis using a urine test with artificial intelligence

22/01/2021

Successful precision cancer diagnosis through an AI analysis of multiple factors of prostate cancer. Potential application of the precise diagnoses of other cancers by utilizing a urine test.
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Image: high-throughput sequencing technology; Copyright: SoulPicture|Kiel, IKMB University of Kiel

Blood group co-determines composition of the intestinal microbiome

21/01/2021

Chronic inflammatory bowel disease (CIBD) in particular is suspected to be closely linked to the composition and (im-)balance of the intestinal microbiome. However, the causal relationship between the microbiome and the development of disease and determining factors of the composition of the microbiome in the individual are still largely unexplained.
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Image: bone tissue; Copyright: PantherMedia / eranicle

New method heals skeletal injuries with synthetic bone

21/01/2021

Researchers at Lund University in Sweden, in collaboration with colleagues in Dresden, Germany, have developed a way of combining a bone substitute and drugs to regenerate bone and heal severe fractures in the thigh or shin bone.
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Image: researching cartilage under a microscope; Copyright: Medical University of Vienna

Cartilage matrix for cartilage regeneration

20/01/2021

Just a few millimetres thick, articular cartilage plays a crucial role in our musculoskeletal system, since it is responsible for smooth (in the truest sense of the word) movement. However, the downside of its particular structure is that even minor injuries do not regenerate. Timely treatment of cartilage damage is therefore essential.
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Image: 3D slices from collagen hydrogel in the shape of a human heart; Copyright: Batalov et al., PNAS, 2021

Lasers and molecular tethers create platforms for tissue engineering

19/01/2021

Imagine going to a surgeon to have a diseased or injured organ switched out for a fully functional, laboratory-grown replacement. This remains science fiction and not reality because researchers today struggle to organize cells into the complex 3D arrangements that our bodies can master on their own.
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Image: Image of human cervix tissue and organoids derived from ectocervical stratified squamous and endocervical columnar epithelial stem cells; Copyright: JMU

Organoid Models: Illuminating Path to Cervical Cancers

19/01/2021

Organoids are increasingly being used in biomedical research. These are organ-like structures created in the laboratory that are only a few millimetres in size. Organoids can be used to study life processes and the effect of drugs. Because they closely resemble real organs, they offer several advantages over other cell cultures.
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Image: damaged mitochondria (dark grey areas) released from human lungs; Copyright: WANDY BEATTY

Test identifies COVID-19 patients at high risk of severe disease

18/01/2021

One of the most vexing aspects of the COVID-19 pandemic is doctors' inability to predict which newly hospitalized patients will go on to develop severe disease, including complications that require the insertion of a breathing tube, kidney dialysis or other intensive care.
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Image: A transparent chip; Copyright: Advanced Manufacturing and Materials Lab

Detecting COVID-19 antibodies in 10-12 seconds

15/01/2021

Researchers at Carnegie Mellon University report findings on an advanced nanomaterial-based biosensing platform that detects, within seconds, antibodies specific to SARS-CoV-2, the virus responsible for the COVID-19 pandemic. In addition to testing, the platform will help to quantify patient immunological response to the new vaccines with precision.
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Image: Smiling man with a dark suit in front of a window; Copyright: Sven Döring

Stem cells against blindness: ERC Proof of Concept

11/01/2021

Prof. Volker Busskamp from the University of Bonn has received a "Proof of Concept Grant" worth 150,000 euros from the European Research Council (ERC). He and his team are working at the Eye Clinic of the University Hospital Bonn on a technology to rapidly program human stem cells to photoreceptor for retinal research and treating blindness in the future.
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Image: a gene (in green); Copyright: Henrik Bringmann

Natural antibiotics produced in wounds increase sleep and survival

10/12/2020

When wounded, our body sets off a complex immune response. As part of it, the wound produces small antimicrobial molecules to fight off the pathogens locally. They signal across tissues from the site of injury to the brain, sending a message to increase sleep and raise the chances for surviving the injury. The results have been published in the journal "Current Biology".
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Image: lung sound recording device; Copyright: TU Graz

COVID-19: Screening system for lung sound analysis

08/12/2020

Our bodies constantly make sounds that are not always audible to the naked ear. The occurrence of certain noises or changes in normal sounds can be an indication of illness. Using the example of the lung, a research team at Graz University of Technology has been intensively engaged in noise recording and the development of computer-aided analysis methods as a supplement to medical diagnosis.
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Image: electrochemical sensing platform; Copyright: University of Illinois

Detecting COVID-19 with paper-based electrochemical sensor

08/12/2020

As the COVID-19 pandemic continues to spread across the world, testing remains a key strategy for tracking and containing the virus. Bioengineering graduate student, Maha Alafeef, has co-developed a rapid, ultrasensitive test using a paper-based electrochemical sensor that can detect the presence of the virus in less than five minutes.
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Image: in-droplet cell separation microfluidic chip; Copyright: Dr. Arum Han/Texas A&M University College of Engineering

Microfluidic system may unravel how novel pathogens attack

02/12/2020

To develop effective therapeutics against pathogens, scientists need to first uncover how they attack host cells. An efficient way to conduct these investigations on an extensive scale is through high-speed screening tests called assays.
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Image: device for detecting antibiotic-resistant bacteria; Copyright: Seokheun

New device offers faster way to detect antibiotic-resistant bacteria

01/12/2020

Bacterial infections have become one of the biggest health problems worldwide, and a recent study shows that COVID-19 patients have a much greater chance of acquiring secondary bacterial infections, which significantly increases the mortality rate.
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Image: researchers in the laboratory next to a microscope wearing masks; Copyright: Alexander Spreinat

Detecting bacteria with fluorescent nanosensors

01/12/2020

Researchers from Bochum, Göttingen, Duisburg and Cologne have developed a new method for detecting bacteria and infections. They use fluorescent nanosensors to track down pathogens faster and more easily than with established methods.
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Image: cancer cell; Copyright: PantherMedia / dtkutoo

Cell therapies for cancer powered by big data

27/11/2020

Finding medicines that can kill cancer cells while leaving normal tissue unscathed is a Holy Grail of oncology research. In two new papers, scientists at UC San Francisco and Princeton University present complementary strategies to crack this problem with "smart" cell therapies.
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Image: close-up image of lung-on-chip model; Copyright: Vivek Thacker (CC BY 4.0)

Lung-on-chip: body's response to early tuberculosis infection

25/11/2020

Findings reveal the early events that take place during tuberculosis infection, and provide a model for future research into respiratory and other infections. Scientists have developed a lung-on-chip model to study how the body responds to early tuberculosis (TB) infection, according to findings published today in eLife.
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Image: Enlarged biosensor lens; Copyright: Khademhosseini Lab

Contact lenses for diagnostic and therapeutic use

24/11/2020

Human bodily fluids and secretions contain molecules known as biomarkers that contain a wealth of information about the body's health and the presence of disease. Among secretions such as tears, sweat and saliva, tears are considered the best source of biomarkers, with concentrations similar to those found in blood.
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AMD RT-qPCR Respiratory Panels

16/11/2020

New for MEDICA 2020 AMD is excited to introducing our four new Respiratory Panels.  Viruses that affect the human respiratory system manifest themselves in a number of ways, with most people...
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Image: doctor in white coat is standing in front of a window; Copyright: Colleen Kelley/University of Cincinnati

Elastic-free face masks can help some with allergies during COVID-19

16/11/2020

A University of Cincinnati immunologist is recommending that individuals with contact dermatitis choose facial masks made without elastic or rubber that allow them to stay safe in the midst of COVID-19 while avoiding possible allergic reactions.
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New Reagent for Direct Determination of HDL-cholesterol

16/11/2020

DiaSys is pleased to offer HDL-c direct FS, a new homogenous assay for direct determination of HDL-cholesterol (HDL-C). HDL-C monitoring is of great importance for cardiovascular risk assessment since...
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CAMPTON Diagnostics presents fully automated point-of-care platform for fast test results

16/11/2020

CAMPTON Reader 100 enables the detection of biomarkers e.g. for infections, cancer, autoimmune or other diseases from a whole blood sample within a few minutes Serological and molecular biological...
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Blood Viscosity: The Test that can Save The World?

13/11/2020

2020 has been a strange year all round. An unknown virus, probably originating in a bat colony in central China, mutated to allow it to also infect humans. Within three months of the virus being...
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Why blood viscosity testing could be an important key for Covid-19 treatment

13/11/2020

Blood thickness is emerging as an important indicator of dangerous complications in Covid-19 patients, causing demand for the blood viscometers manufactured by Benson Viscometers in West Wales to...
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Image: golden platinum; Copyright: PantherMedia / agsandrew

Algorithm identifies previously undetected cancer driver genes

13/11/2020

A new study, led by researchers from the University of California, Irvine, has deepened the understanding of epigenetic mechanisms in tumorigenesis and revealed a previously undetected repertoire of cancer driver genes. The study was published this week in Science Advances.
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Why a simple blood test could identify those most at risk of Covid-19 complications

13/11/2020

One of the biggest challenges facing medical teams treating Covid-19 patients is identifying which ones are likely to suffer the most extreme responses to the virus. Knowing this would make it...
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Plasma Viscosity in Covid-19

13/11/2020

Covid-19, or SARS-COV-2, which emerged in late 2019, continues to spread around the world, infecting more than 4.5m people at time of writing, and leading to more than 300,000 deaths.   The...
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New for MEDICA 2020

13/11/2020

Test for the detection of coronavirus SARS-CoV-1/2 (COVID-19)   A new severe respiratory syndrome caused by a coronavirus was first observed in Wuhan (China) in December 2019. The infection has...
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Image: fully covered doctor with diagnostic test in his hand; Copyright: PantherMedia / Erika Eros

Rapid test can ID unknown causes of infections throughout the body

12/11/2020

UC San Francisco scientists have developed a single clinical laboratory test capable of zeroing in on the microbial miscreant afflicting patients hospitalized with serious infections in as little as six hours -- irrespective of what body fluid is sampled, the type or species of infectious agent, or whether physicians start out with any clue as to what the culprit may be.
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Fraunhofer ENAS presents a rapid virus test for the detection of the SARS-CoV-2 virus and an electronic wound patch to stimulate healing processes at virtual.COMPAMED 2020

12/11/2020

Get a proof of infection with the SARS-CoV-2 virus or of immunity to the virus within one hour. Accelerate healing processes with electrical stimulation through an active wound patch. Fraunhofer ENAS...
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ACON announces the launch of its Flowflex™ Antigen COVID-19 Test

12/11/2020

San Diego, CA, November 2, 2020 —  ACON Laboratories, Inc., a leading global medical device manufacturer announced today the launch of its Flowflex™ SARS-COV-2 Antigen Rapid Test.  The...
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iXensor gears up to launch the PixoTest® COVID-19 Antigen Test and PixoHealth Pass

11/11/2020

PixoTest® is among the fastest COVID-19 antigen tests for smarter pandemic management, detecting positive SARS-CoV-2 infection in as short as five minutes. The PixoTest® POCT Analyzer offers...
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Image: mouse fibroblast cell imaged on a metasurface; Copyright: Kaoru Tamada, Kyushu University

Higher-resolution imaging of cells using plasmonic metasurfaces

09/11/2020

In the quest to image exceedingly small structures and phenomenon with higher precision, scientists have been pushing the limits of optical microscope resolution, but these advances often come with increased complication and cost.
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Image: woman on home-bike wears mask during training; Copyright: John Ko

Face masks don't hinder breathing during exercise

06/11/2020

A new University of Saskatchewan (USask) study has found that exercise performance and blood and muscle oxygen levels are not affected for healthy individuals wearing a face mask during strenuous workouts.
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Good news: Chemtron's COVID-19 Antibody Test Kit has approved by CE Certification

06/11/2020

Shanghai Chemtron's  new coronavirus (2019-nCoV) IgM/IgG antibody rapid test kit (colloidal gold ) and new coronavirus (2019-nCoV) IgM antibody rapid test kit (colloidal gold ) are...
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STAT-NAT® COVID-19 MULTI, the value of simplicity

05/11/2020

STAT-NAT®COVID-19 MULTI is the new configuration of ready-to-use lyo Real-Time PCR mix for the detection of novel coronavirus disease. The world is experiencing a fast increase of SARS-CoV-2 testing...
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PCR Filters

04/11/2020

Dielectric filter solutions for PCR analyzers Enabling SARS-CoV-2 detection with high-performance fluorescence filters by Optics Balzers Standard off-the-shelf optical filters often struggle to...
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Linear Variable Filters

04/11/2020

Adaptable filters for fluorescence analysis One filter to rule them all – a versatile solution fitting numerous fluorophores High-End fluorescence microscopes as well as fluorescence spectrometers...
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Image: colourful bottles on blue ground; Copyright: Trears

Earwax sampling could measure stress hormone

04/11/2020

A novel method to sample earwax could be a cheap and effective way to measure the hormone cortisol, according to a study led by researchers at UCL and King's College London.
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Image: implant in hand and attached to heart; Copyright: University of Houston

Implantable device can monitor and treat heart disease

04/11/2020

Pacemakers and other implantable cardiac devices used to monitor and treat arrhythmias and other heart problems have generally had one of two drawbacks - they are made with rigid materials that can't move to accommodate a beating heart, or they are made from soft materials that can collect only a limited amount of information.
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Image: Hand and Arm; Copyright: PantherMedia / eskymaks (YAYMicro)

New artificial skin functions like natural skin

03/11/2020

Researchers at the RIKEN Center for Biosystems Dynamics Research have developed human-skin equivalent that reproduces traction-force balance in the lateral direction, a property that controls the structure and physiological function of skin. This artificial skin will enhance in-depth analyses of physiological skin functions.
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Image: kidnes; Copyright: PantherMedia / dileep (YAYMicro)

Biomarker combination predicts kidney injury in critically ill children

02/11/2020

Researchers at the University of Liverpool have identified a unique method of identifying the early signs of a potentially serious condition known as Acute Kidney Injury (AKI).
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Image: Chromosome segregation in a human stem cell; Copyright: Carolina Pereira & Inês Milagre

Stem cells: new insights for future regenerative medicine approaches

30/10/2020

Researchers discover that a specialized part of the chromosomes, essential for a correct cell division, is smaller and weaker in stem cells, when compared to the ones of differentiated cells.
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Elevated red blood cell distribution width (RDW) is associated with the risk of Covid-19 mortality

26/10/2020

During this Coronavirus crisis, all the attention of clinicians around the world lays on the direct diagnosis of the COVID-19 disease, whether by PCR, Rapid Tests or classical serology. However, cell...
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NLR parameter in Icon-5 and Icon-5 OP hematology analyzers to battle COVID-19

25/10/2020

The Covid-19 pandemic is affecting the whole world and Norma is dedicated to contribute and help to this still growing and sadly, worsening virus outbreak that is threatening many of our lives...
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Genrui released affordable, high-quality Covid-19 antigen rapid test kits

23/10/2020

Genrui Biotech Inc. released SARS-CoV-2 Antigen Test Kit (Colloidal Gold)-affordable, high-quality Covid-19 antigen rapid tests. The antigen test kits are highly portable, reliable, easy to...
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Iceni Diagnostics appoint BBI to produce their Covid-19/Influenza test

10/10/2020

Original article published on 10/10/2020 Iceni Diagnostics has appointed BBI Solutions to generate clinical trial batches for their new, rapid SARS-COV-2/Influenza virus detection test. The test...
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SYnabs, Unisensor, Coris BioConcept and Bio-X Diagnostics, have together developed a COVID individual rapid test that is a world premiere

08/10/2020

Unlike the products marketed to date, the test developed by SYnabs, Coris BioConcept, Unisensor, and Bio- X Diagnostics, is the only rapid solution (developed in different formats) that can detect an...
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ASKION Online - A new Website for a strong Team

08/10/2020

ASKION - Mid-sized technology company from Gera that went around the world   Since 15 years ASKION is a reliable provider of customer specific devices and assemblies. Our know how and experience...
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MEDICAL FAIR ASIA 2020 goes Digital with Online Convenience for Medical Sourcing Needs

22/09/2020

MEDICAL FAIR ASIA 2020 goes Digital with Online Convenience for Medical Sourcing Needs Ten-day digital experience for a vibrant marketspace to conduct business 24/7 Singapore, 22 September 2020 –...
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BBI creates new jobs to support next phase in COVID-19 home test development

20/08/2020

BBI Solutions is recruiting for roles to support its work as part of a UK Government consortium, tasked with developing and manufacturing a Covid-19 Point of Care antibody test to support the...
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BBI Solutions Partners with Avacta Group PLC as COVID-19 Rapid Antigen Test Manufacturer

06/08/2020

BBI Solutions is pleased to announce it has been appointed to manufacture the saliva-based rapid SARS-COV-2 antigen test that is being developed by Affimer® biotherapeutics and reagents developer...
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Image: diagnostic test on a table; Copyright: beta web GmbH/Melanie Prüser

Single-use tests: sensitivity and easy use combined for diagnostics

12/12/2019

Diagnostic testing usually takes some time and a sterile environment to get the results. To cut down on the costs and effort spend on these tasks there are different diagnostic tests. One of them are single-use tests offered by SensDx S.A. The technology behind them not only makes the process faster and easier, but provides the opportunity to expand into home use in the future as well.
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Image: Blood sample labelled

Cardiac diagnostics – prompt and personalized

08/11/2019

If physicians suspect an acute myocardial infarction, they first order an ECG. This test is very established and allows cardiologists to quickly diagnose acute heart attacks – though the test does not detect less common heart attack symptoms. So far, those patients had to wait up to twelve hours before a heart attack could be accurately diagnosed or ruled out. But things are about the change.
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Image: Flags are blowing in the wind to the backdrop of a dark evening sky; Copyright: Messe Düsseldorf/ctillmann

Medicine at the pulse of time: Innovations and trends at MEDICA 2019

04/11/2019

Soon, the world's largest trade fair for medical technology will open its doors again: More than 5.000 exhibitors will present their newest products and ideas at MEDICA from 18 to 21 November. You will not only meet well-known companies here, but also lots of young start-ups. Or, you can visit the MEDICA forums and conferences to experience a rich program of lectures and discussions.
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Image: A little toy figure of a man in a suit is standing on a print-out of DNA sequencing; Copyright: panthermedia.net/filmfoto

MEDICA LABMED FORUM: full speed ahead for careers in laboratory medicine

04/11/2019

Laboratories are medicine’s secret weapon because they handle the lion’s share of diagnostics often without patients even realizing it. That’s why the continuing workforce shortage in both laboratory medicine and companies is especially troubling. The MEDICA LABMED FORUM 2019 plans to address and counteract this development.
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Image: Volker Bruns; Copyright: Fraunhofer ISS

AI software: "iSTIX opens your world to the possibilities of digital pathology"

08/10/2019

The healthcare market offers a multitude of microscopes that make cells visible to the human eye. The same applies to AI-based software for image analysis. After taking the microscopic images, scientist are faced with large volumes of scans with usually low resolution. Yet when all aspects merge together, they open up a the world of digital pathology.
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Image: Man with mouthguard and laboratory glasses holding Petri dish up; Copyright: panthermedia.net/kasto

Cardiac Tissue Engineering: a heart out of the Petri dish

23/09/2019

For patients waiting for donor organs, every day can mean the difference between life and death. Making things even more complicated is the fact that not every organ is a compatible match with the patient. It would mean enormous progress if we could grow organs from the patient's own cells in the lab. That's why patients with heart disease place big hope in tissue engineering.
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Image: Laboratory situation - Prof. Popp shows a young man a small object in his hand; Copyright: Leibniz-IPHT/Sven Döring

Tumor excision: triple imaging for unique diagnostics

08/08/2019

After their tumor has been removed, some patients have to return to the hospital to undergo surgery again. That's because the tumor was not precisely identified and was subsequently not completely removed. That's both an ethical and financial dilemma. A new surgery-adjacent procedure is designed to rapidly and accurately detect tumors.
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Image: A man is holding a hand full of pill blisters with antibiotics; Copyright: panthermedia.net/alexkalina

Combating antibiotic resistance: One step ahead through technology

01/08/2019

Antibiotic resistance is on the rise in all parts of the world, complicating medical treatment of serious bacterial infections in patients. The World Health Organization estimates that approximately 33,000 people die each year from antibiotic-resistant bacteria in Europe alone. Bacteria that are resistant to multiple or even all known antibiotics pose an ever-increasing threat.
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Image: A lab technician is using a pipette to fill a solution into a petri dish; Copyright: panthermedia.net/Arne Trautmann

Last-resort antibiotics: "We can identify carbapenemases within half an hour"

01/08/2019

Antibiotic resistance is modern medicine's greatest challenge. Some bacteria only respond to a handful of antibiotics, prompting hospitals to spend a lot of time finding an effective drug. That’s why it is critical for physicians to rapidly identify antibiotic resistance to avoid ineffective treatments.
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Image: Two petri dishes with different kinds of agar plates on which bacterial cultures are growing; Copyright: panthermedia.net/photographee.eu

Antibiotic resistance: technical tricks against pathogens

01/08/2019

An untreatable infection is a nightmare for physicians and potentially life-threatening to the patient. Unfortunately, more and more pathogens emerge that are resistant to drugs, especially antibiotics. We need to use our drugs smartly and come up with technical solutions as well to prevent our weapons from blunting in the future.
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Image: A greenly lit laboratory device; Copyright: Sven Döring

Photonics: "We want a rapid and easy method to identify pathogens and antibiotic resistance"

01/08/2019

The medical devices value chain has gaps between academic research and industrial practice that slow down innovation processes. This also applies to time-sensitive and urgently needed products such as rapid diagnostic tests to identify resistant pathogens. At the InfectoGnostics Research Campus in Jena, partners from research and medicine team up to close these gaps.
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Image: Flags; Copyright: SilverSky LifeSciences GmbH

Striking new paths in medicine - Diagnostics Partnering Conference 2019

08/07/2019

On November 18th, 2019, parallel to the first day of MEDICA, the world forum for medicine, the Diagnostics Partnering Conference (DxPx Conference) will take place in Düsseldorf, bringing together stakeholders in the diagnostics and research tool industry. The DxPx Conference focuses on discovering technologies, finding financing and investment opportunities and forming collaborative partnerships.
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Image: Ellipsoid of revolution with a gold coating to detect backscattered photons from the skin tissue; Copyright: Sven Delbeck/Fachhochschule Südwestfalen

Blood Sugar Monitoring: Using Infrared Instead of Invasive Techniques

22/03/2019

Over six million people in Germany have diabetes. It is estimated that almost 400 million people are affected by this disease worldwide. Diabetes sufferers must prick their fingers several times a day to monitor their blood sugar.
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Picture: Woman sleeping sideways in bed with a breathing mask; Copyright: Philips GmbH

Comprehensive Treatment: It’s All About Breathing

01/03/2019

Coughing, airway obstruction, difficulty breathing: Chronic obstructive pulmonary disease (COPD) is an umbrella term used to describe progressive and currently incurable lung diseases. The innovative solutions of Philips Respironics help patients to manage each stage of the disease and their medication intake, train the respiratory system and provide respiratory support.
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Image: Cell cultivation in a Petri dish; Copyright: panthermedia.net / matej kastelic

Organ-on-a-chip – Organs in miniature format

01/02/2019

In vitro processes and animal tests are used to develop new medications and novel therapeutic approaches. However, animal testing raises important ethical concerns. Organ-on-a-chip models promise to be a feasible alternative. In a system the size of a smartphone, organs are connected using artificial circulation.
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Image: Man and woman in a laboratory presenting a multi-organ chip; Copyright: TissUse GmbH

Multi-Organ Chips – The Patients of Tomorrow?

01/02/2019

The liver, nervous tissue or the intestines: all are important human organs that have in the past been tested for their function and compatibility using animal or in vitro test methods. In recent years, TissUse GmbH, a spin-off of the Technical University of Berlin (TU Berlin), has launched multi-organ chip platforms. But that’s not all.
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Image: Graphic rendering of several cells in a petri dish; Copyright: panthermedia.net/dani3315

Organ-on-a-chip systems: limited validity?

01/02/2019

Organ-on-a-chip systems are technically a great enhancement of medical research because they facilitate testing of active ingredients on cell cultures in the chambers of a plastic chip. This replaces animal testing and improves patient safety. That being said, they are not a true-to-life replication of the human body and can only simulate a few functions and activities.
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Image: Cells in a Petri dish; Copyright: panthermedia.net / devserenco

Organ-on-a-chip - the mini organs of the future?

01/02/2019

So far in vitro methods and animal experiments have been used to determine the causes of diseases, research therapeutic approaches and predict the effect of drugs. Organ-on-a-chip models now offer a more accurate and ethically justifiable alternative. Find out more about the models, their advantages and future developments in our Topic of the Month.
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Image: Glucometer next to a smartphone that shows the blood glucose level; Copyright: panthermedia.net/simpson33

DiaDigital: making sense of diabetes apps

02/01/2019

While they are very useful, health apps have one major drawback: anyone can release and distribute them unchecked. Only some apps require medical device certification. So how can users spot a great, safe and useful app? When it comes to diabetes apps, the “DiaDigital” seal of distinction is the answer.
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Image: Woman at the table operating a smartphone and surrounded by utensils for diabetes therapy; Copyright: panthemedia.net/Lev Dolgachov

Diabetes digital – smart support for diabetics

02/01/2019

Monitoring blood sugar levels, counting carbohydrates, calculating insulin doses, and keeping accurate records - diabetes is a data-intensive disease that demands a lot of self-discipline and attention from the patients. Some concerns are patients neglecting to keep a food journal, "fudged" test results or calculation errors. Digital solutions help patients easily manage the large volumes of data.
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Image: digital capture of an eye; Copyright: panthermedia.net / cosmin momir

A digital look inside the human eye – when algorithms diagnose Diabetes

02/01/2019

Diabetes mellitus or simply diabetes has become very common and is often described as a lifestyle disease. More and more people are suffering from this chronic metabolic disorder. Next to established diagnostic procedures, digital retinal screening has shown to be successful - a promising technique that will also play an important role in the diagnosis of other diseases in the future.
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Image: Woman with diabetes and a sensor; Copyright: panthermedia.net / Click and Photo

Blood glucose monitoring of tomorrow - modern diabetes therapies

02/01/2019

There are 425 million people with diabetes in the world. Heart problems, kidney failure or blindness - these can all be consequences of the metabolic disease. Diabetes patients now have the possibility of being treated digitally.
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Photo: Preview picture of video

From algorithm to rapid test – Artificial Intelligence classifies blood cells

21/11/2018

Our blood reveals a lot about our physical health. The shape of our blood cells sheds light on several hereditary diseases for example. For a diagnosis, the cells must first be examined under the microscope and categorized into a specific cell class. We met with Dr. Stephan Quint and Alexander Kihm of the Institute of Physics at the Saarland University, who explained how this classification works.
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Image: preview picture of the video

Past, present and future of MEDICA – Interview with Horst Giesen

12/11/2018

Even before MEDICA begins, the Düsseldorf trade fair grounds are alive like a beehive: in the halls, stands are built and exhibits are delivered, while the trade fair management coordinates logistics and services for exhibitors and visitors. We were still able to have a short talk to Horst Giesen, Global Portfolio Director Health & Medical Technologies of Messe Düsseldorf, despite all the bustle.
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Image: several leg pairs during a run; Copyright: panthermedia.net/lzf

Diagnostics at record speeds – POCT in high-performance sports

02/11/2018

This is what diagnostic investigation normally looks like: a patient sample is collected, sent to the laboratory and analyzed. Once that's completed, the patient is told of the lab test result. But if the patient is a high-performance athlete and has to follow and stick to a rigid training schedule, he or she needs these results immediately. What makes this possible? Point-of-care testing!
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Image: visitors at MEDICA; Copyright: Messe Düsseldorf

See, experience, learn: what's new at MEDICA 2018

02/11/2018

It's time: the world's largest medical trade fair opens its doors from 12 to 15 November. More than 5,000 international exhibitors will present their new innovative products and applications. Frums, conferences and special shows will feature exciting specialist lectures and discussions that will give you an insight into electromedicine, laboratory medicine, medical technology and diagnostics.
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Image: Maria Driesel and her colleagues from inveox next to the new device; Copyright: Astrid Eckert

Pathology 4.0 – inveox automates laboratory processes

22/08/2018

Mix-ups, contamination and sample loss – most errors in pathology happen when specimen are received. Countless samples arrive daily at the laboratory, while the sample entry process is very monotonous. As a result, the work is inefficient. The start-up company inveox has now developed a system that automates the processes in the pathology laboratory, thus making them more efficient.
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Image: Small brown mole on the back of a hand; Copyright: panthermedia.net/Mario Hahn

Early detection: Tattoo signals cancer – and more

09/07/2018

People who are not ill and do not show any symptoms typically do not visit the doctor. And while most people know that preventive medical checkups for cancer, for example, are important, they still avoid them. They tend to be very hesitant because the doctor might detect a serious illness. In the future, a new type of implant could make it easier to go to a screening test.
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Image: AcCellerator research device at an exhibition stand; Copyright: Daniel Klaue, ZELLMECHANIK DRESDEN GmbH

Cells in the speed trap – diagnosis in a matter of seconds

22/06/2018

A drop of blood provides a lot of valuable information. However, it takes several hours to analyze the blood of a patient and make a diagnosis. This takes away a lot of time that's crucial for treatment. A new method intends to considerably speed up this process by testing the cells in the blood in terms of their deformability and immune response.
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Photo: Preview picture of video

Personalized cancer medicine – Best possible treatment with TherapySelect

30/04/2018

Medicine is getting more and more personalized. This is particularly interesting for oncology, since a cancer is as individual as the respective patient. When choosing a therapy, both the characteristics of the tumor and the personal characteristics of the patient must be considered. To see exactly what this looks like, we visited the diagnostics company TherapySelect, based in Heidelberg.
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Image: Two hands are holding a tubular frame that is carrying a glistening wet, white tube; Copyright: Leibniz University of Hanover/Institute of Technical Chemistry

Tissue engineering: how to grow a bypass

23/04/2018

A bypass is a complicated structure. It is either made of synthetic materials that can cause blood clots and infections or created by using the patient’s veins. However, the latter often does not yield adequate material. A newly developed bioreactor could solve this problem in the future. It is designed to tissue engineer vascular grafts by using the body’s own material.
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Image: Three men in suits and a woman in a laboratory coat are standing in a laboratory; Copyright: Ministry of Economy of Mecklenburg-Hither Pomerania/Norbert Fellechner

On the trail of cancer: personalized cancer vaccine

01/03/2018

Conventional cancer treatment selection typically depends on the location of the tumor. However, this approach ignores the distinct gene mutations in the tumor of the individual patient. New cancer research approaches increasingly emphasize the concept of personalized therapy.
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Image: Several colorful pills placed on a target, one of them is in the center; Copyright: panthermedia.net/georgemuresan

Personalized Medicine – focused on healing

01/03/2018

Personalized medicine does not want to measure all patients with the same yardstick anymore. Instead, it aims to precisely fit the therapy to the cause of their disease. This often means a more successful treatment with less side effects for patients. And for physicians, interdisciplinary cooperation and decision making come to the fore.
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Image: A group of physicians is holding large colorful puzzle pieces in their hands and is putting them together; Copyright: panthermedia.net/Andriy Popov

Personalized medicine: a paradigm shift is gaining momentum

01/03/2018

Personalized medicine does not follow a "one-size-fits-all" treatment approach but emphasizes a "tailor-made" paradigm, meaning a treatment is customized to each individual person's case. For patients, this increases the chances of treatment success and means fewer side effects. While the approach originates in the field of oncology, it is now also increasingly applied to other disease patterns.
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Image: yellow tape measure with capsules in front of it; Copyright: panthermedia.net/Jiri Hera

Personalized cancer medicine: customized treatment

01/03/2018

Everyone is different. This statement also applies to our health. Cancer, in particular, can look and progress differently depending on the individual person. That’s why every patient ideally also needs a customized treatment that is tailored to their individual needs. But how feasible is this idea?
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Image: a container with the nutrient medium for cancer cells; Copyright: Dr. Markus Wehland

Cells in space – extraterrestrial approaches in cancer research

22/02/2018

Here on Earth, all experiments are bound by gravitation. Yet, freed from gravity's grip, tumor cells, for example, behave in an entirely different way. As part of the "Thyroid Cancer Cells in Space" project by the University of Magdeburg, smartphone-sized containers carrying poorly differentiated thyroid cancer cells are sent into space.
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"Spray-On" muscle fibers for biomimetic surfaces

08/01/2018

Few patients with heart failure are fortunate enough to receive a donor's heart. Ventricular assist devices (or heart pumps) have been around for several years and are designed to buy time as patients wait for a transplant. Unfortunately, the body doesn't always tolerate these devices.
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