Laboratory Equipment / Diagnostic Tests -- MEDICA - World Forum for Medicine

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Image: Unconcious girl in a hospital bed; Copyright: panthermedia.net/Monkeybusiness Images

eHealth: Records could improve pediatric sepsis surveillance

06.12.2019

Sepsis is a major public health problem, contributing to substantial disability, death, and healthcare costs in the United States among both adults and children. Though sepsis is the focus of worldwide prevention and quality improvement efforts, tracking sepsis rates and outcomes is challenging because a definitive diagnostic test does not yet exist.
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Image: A physician is holding a plastic cup for urine samples; Copyright: panthermedia.net/terovesalainen

Diagnostics: New home urine test for prostate cancer

02.12.2019

A simple urine test under development for prostate cancer detection can now use urine samples collected at home - according to new research from University of East Anglia and the Norfolk and Norwich University Hospital.
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Image: Diascopic's iON platform next to a laptop; Diascopic, LLC

AI: startup developing tool for tuberculosis detection

27.11.2019

Diascopic LLC, a Cleveland-based medical research company that develops diagnostic technology, will use a highly competitive federal grant to develop and apply new artificial intelligence (AI) and digital pathology tools for detecting tuberculosis (TB).
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Image: view on the hands of a laboratory worker; Copyright: K. Dobberke für Fraunhofer ISC

Tissue Engineering: new ways to avoid animal testing

26.11.2019

Around 60 international experts met on November 7 at the Fraunhofer Institute for Silicate Research ISC in Wuerzburg to report on the state of the art in the field of 3D tissue models and prevention of animal experiments in the development of pharmaceuticals and medical devices.
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MEDICA 2019 – Visitors can expect novelties about novelties

18.11.2019

A wearable that controls your posture, catheters with AI and home care with robot support – these are only some of the highlights that visitors can expect at MEDICA from 18 to 21 November in Düsseldorf. Our editorial team has already been able to have a look at Sunday.
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Innovative drain disinfectant that kills and prevents biofilms launched at MEDICA 2019

18.11.2019

Infection prevention specialist GAMA Healthcare is launching a ground-breaking drain disinfectant at MEDICA 2019 that kills, removes and prevents formation of biofilms, including the highly resistant...
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World’s first digital testing device for early bowel cancer screening showcased at MEDICA 2019

18.11.2019

Oxford MEStar – an Oxford University bioengineering spinout company – will be joining the ABHI UK Pavilion at MEDICA 2019 (18 – 21st November 2019) to showcase the world’s first digital Faecal...
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Image: graphic illustration of breast cancer; Copyright: panthermedia.net/decade3d

Cells: blocking metastasis-promoting enzyme

15.11.2019

In a breakthrough with important implications for the future of immunotherapy for breast cancer, UC San Francisco scientists have found that blocking the activity of a single enzyme can prevent a common type of breast cancer from spreading to distant organs.
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Image: woman in a bed gets treated by a doctor; Copyright: panthermedia.net/anetta

Diabetes: women most affected by vascular complications

14.11.2019

Women are most affected by the vascular complications of diabetes - a situation likely to escalate in the coming decades, reports a paper published on World Diabetes Day in the European Journal of Preventive Cardiology, a journal of the European Society of Cardiology (ESC). Cardiovascular disease occurs 15 years earlier in patients with diabetes and is their main cause of morbidity and mortality.
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FIND Collaborate with SpeeDx and QuantuMDx

14.11.2019

The Foundation for Innovative New Diagnostics (FIND) are supporting a collaboration with SpeeDx and QuantuMDx to assess the feasibility of developing low-cost point of care (POC) tests for...
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Image: biosensor platform consisting of graphene layers; Copyright: Letao Yang, KiBum Lee, Jin-Ho Lee and Sy-Tsong (Dean) Chueng

Biosensor: technology created for stem cells

12.11.2019

A Rutgers-led team has created better biosensor technology that may help lead to safe stem cell therapies for treating Alzheimer's and Parkinson's diseases and other neurological disorders.
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Canada at MEDICA, Düsseldorf (November 18 - 21, 2019)

11.11.2019

Biggest Canadian Participation Ever MEDICA – the leading international medical tradeshow – has been attracting generations of Canadian visitors and exhibitors. This year, 59 Canadian medical...
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Image: depiction of cells; Copyright: Yu Jung Shin

Cells: oxygen-starved tumor cells promoting cancer spread

08.11.2019

Using cells from human breast cancers and mouse breast cancer models, researchers at the Johns Hopkins Kimmel Cancer Center say they have significant new evidence that tumor cells exposed to low-oxygen conditions have an advantage when it comes to invading and surviving in the bloodstream.
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Image: depiction of a disruption of immune cells; Copyright: Gerrit Müller/Freie Universität Berlin

Immunology: why beta-blockers cause skin inflammation

08.11.2019

Beta-blockers are often used to treat high blood pressure and other cardiovascular diseases. However, in some patients they can trigger or exacerbate psoriasis, an inflammatory skin disease. Scientists at the University of Bonn and Freie Universität Berlin have now found a possible cause for this. Their results have been published in the renowned journal "Autophagy".
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Linnodee Diagnostics Ltd - specialising in veterinary diagnostic tests for Leptospirosis

08.11.2019

Linnodee Diagnostics Ltd. is dedicated to the design and manufacture of clinical and veterinary diagnostic tests for Leptospirosis. The company was established in 1999 by the late Dr Ernest F Logan...
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Image: Blood sample labelled

Cardiac diagnostics – prompt and personalized

08.11.2019

If physicians suspect an acute myocardial infarction, they first order an ECG. This test is very established and allows cardiologists to quickly diagnose acute heart attacks – though the test does not detect less common heart attack symptoms. So far, those patients had to wait up to twelve hours before a heart attack could be accurately diagnosed or ruled out. But things are about the change.
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Illustration: RNA interaction surface of Fem-3-binding-factor 2 as predicted by NucleicNet; Copyright: 2019 KAUST

AI: revealing the nature of RNA-protein interactions

05.11.2019

A new computational tool developed by KAUST scientists uses artificial intelligence (AI) to infer the RNA-binding properties of proteins. The software, called NucleicNet, outperforms other algorithmic models of its kind and provides additional biological insights that could aid in drug design and development.
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Image: Flags are blowing in the wind to the backdrop of a dark evening sky; Copyright: Messe Düsseldorf/ctillmann

Medicine at the pulse of time: Innovations and trends at MEDICA 2019

04.11.2019

Soon, the world's largest trade fair for medical technology will open its doors again: More than 5.000 exhibitors will present their newest products and ideas at MEDICA from 18 to 21 November. You will not only meet well-known companies here, but also lots of young start-ups. Or, you can visit the MEDICA forums and conferences to experience a rich program of lectures and discussions.
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Image: A little toy figure of a man in a suit is standing on a print-out of DNA sequencing; Copyright: panthermedia.net/filmfoto

MEDICA LABMED FORUM: full speed ahead for careers in laboratory medicine

04.11.2019

Laboratories are medicine’s secret weapon because they handle the lion’s share of diagnostics often without patients even realizing it. That’s why the continuing workforce shortage in both laboratory medicine and companies is especially troubling. The MEDICA LABMED FORUM 2019 plans to address and counteract this development.
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Image: material with scaffold structure; Copyright: Tomsk Polytechnic University

Regenerative medicine: material for cell immune response

04.11.2019

Scientists of Tomsk Polytechnic University jointly with the University of Montana (USA) proposed a new promising material for regenerative medicine for recovery of damaged tissues and blood vessels.
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Image: illustration of different cells; Copyright: peterschreiber.media - stock.adobe.com

Vaccines: super-antibody strategy

01.11.2019

New influenza vaccines are required every autumn, because the viruses constantly change the components to which our immune protection responds. Medical research is focusing on universal vaccines that target more stable parts of the viruses. This new generation of broadly neutralising antibodies is particularly important for controlling life-threatening viral infections.
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Image: molecular simulation close-up; Copyright: Chan Cao, EPFL

Biosensor: made from a dangerous toxin

30.10.2019

Some types of bacteria have the ability to punch holes into other cells and kill them. They do this by releasing specialized proteins called "pore-forming toxins" (PFTs) that latch onto the cell's membrane and form a tube-like channel that goes through it. This hole across the membrane is called a pore. Punctured by multiple PFTs, the target cell self-destructs.
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Image: brain cells in a piece of a mouse cortex; Copyright: J Kuhl (somedonkey.com), Motta, Wissler (c) MPI for Brain Research

Brain mapping: unraveling the dense networks

29.10.2019

The methods to analyze neuronal networks sparsely have been available for decades, the dense mapping of neuronal circuits is a major scientific challenge. Researchers from the MPI for Brain Research have now succeeded in the dense connectomic mapping of brain tissue from the cerebral cortex, and quantify the possible imprint of learning in the circuit.
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Image: a protein adapter in the blood stream; Copyright: MPI-P

Cells: toxin, trauma, therapy?

28.10.2019

The department of Prof. Tanja Weil at the Max Planck Institute for Polymer Research has, in cooperation with the group of Prof. Holger Barth from the Institute of Pharmacology and Toxicology at the Ulm University, shown in initial laboratory tests that they are able to specifically modulate processes in human white blood cells in vitro.
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Oxford MEStar to Announce Launch of measurePRO POC Faecal Occult Blood Test at MEDICA

25.10.2019

 Oxford MEStar will be attending the MEDICA trade fair in Düsseldorf (November 18th-21st 2019) as part of the ABHI UK pavillion in Hall 16 (stand 16K03-3) and announcing the launch of their new...
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Image: medial prefrontal cortex; Copyright: Drs. Christopher Parkhurst and David Artis (WCM)

Cells: gut health influences brain health

25.10.2019

Over the last two decades, scientists have observed a clear link between autoimmune disorders and a variety of psychiatric conditions. For example, people with autoimmune disorders such as inflammatory bowel disease (IBD), psoriasis and multiple sclerosis may also have depleted gut microbiota and experience anxiety, depression and mood disorders.
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Image: triple-coaxial cell printing technology to construct biomimetic tissue-engineered blood vessels; Copyright: Gao et al.

Implant: 3D printing, bioinks create blood vessels

24.10.2019

A biomimetic blood vessel was fabricated using a modified 3D cell printing technique and bioinks, which were formulated from smooth muscle cells from a human aorta and endothelial cells from an umbilical vein.
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Image: diagnostic device and a small tube in a hand; Copyright: panthermedia.net/luchschen

Point-of-care diagnostic: detecting preterm birth

23.10.2019

A new study provides a first step toward the development of an inexpensive point-of-care diagnostic test to assess the presence of known risk factors for preterm birth in resource-poor areas. The study found that measuring levels of TIMP-1 and D-lactic acid in vaginal secretions may be a non-invasive, cost-effective way to assess the risk for preterm birth.
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Image: Cells in a 3D scaffold; Copyright: TU Wien

Bioprinting: living cells in a 3D printer

22.10.2019

Tissue growth and the behavior of cells can be controlled and investigated particularly well by embedding the cells in a delicate 3D framework. This is achieved using additive 3D printing methods - so called "bioprinting" techniques. However, some methods are very imprecise or only allow a very short time window in which the cells can be processed without being damaged.
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Image: ultrastructure of cells; Copyright: Florian Schueder, MPI of Biochemistry

Microscopy: 10-times faster image acquisition

17.10.2019

Recent advances in fluorescence microscopy allow researchers to study biological processes below the classical diffraction limit of light. Ralf Jungmann, Professor for Experimental Physics at Ludwig-Maximilians-Universität in Munich and research group leader at the Max Planck Institute of Biochemistry, and colleagues developed DNA-PAINT, a variant of these so-called super-resolution approaches.
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BioTeZ is starting to develop a new method for directly measuring the primary effect of drugs on their target molecule.

17.10.2019

BioTeZ starts the project for the development of a companion diagnostic procedure. The aim is to determine the optimal drug dose for each patient to reduce side effects, to achieve the Therapeutic...
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Image: PHD Student Melanie Fuller showcasing nanomesh drug delivery; Copyright: Flinders University

Antibiotic resistance: nanomesh drug delivery provides hope

17.10.2019

The fight against global antibiotic resistance has taken a major step forward with scientists discovering a concept for fabricating nanomeshes as an effective drug delivery system for antibiotics. Health experts are increasingly concerned about the rise in medication resistant bacteria.
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BioTeZ established a novel therapeutic drug monitoring assay for Evolocumab and PCSK9

17.10.2019

The first PCSK9 Inhibitors reach the market and BioTeZ just completed the development project for the therapeutic drug and antigen monitoring assay. The recoveryELISA® (RPE) allows the simultaneous...
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Image: a woman's eye; Copyright: panthermedia.net / Rangizzz

AI: Sreening system detects diabetic retinopathy

16.10.2019

New research shows that an automated, artificial intelligence (AI) screening system accurately detects diabetic retinopathy 95.5 percent of the time. The system doesn't require the input of an expert ophthalmologist and it can provide a reading in 60 seconds, making real-time screening possible for primary care practices and diabetes centers.
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Image: a microfluidic chip; Copyright: Sia Lab/Columbia Engineering and OPKO Health

Diagnostics: rapid test for Lyme disease

16.10.2019

Some 300,000 people in the United Stated are diagnosed with Lyme disease every year. Caused by Borrelia burgdorferi and transmitted by the bite of infected Ixodes ticks, the disease if left untreated can cause serious neurologic, cardiac, and/or rheumatologic complications.
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Image: a scanning electron image; Copyright: Melosh Lab

Immunotherapy: novel technique for cancer treatment

15.10.2019

Immunotherapy is a promising cancer treatment that uses genetically modified immune cells to fight cancer. It can be used as a primary treatment or in combination with other treatments such as radiation and chemotherapy to slow down or stop the growth of cancer cells and prevent them from spreading to other parts of the body.
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Image: lung tissue under a microscope; Copyright: Takezaki et al., 2019

Gene: new therapeutic target for pulmonary fibrosis

11.10.2019

Researchers in Japan have identified a genetic mutation that causes idiopathic pulmonary fibrosis (IPF) by killing the cells lining the lung's airways. The study, which will be published October 10 in the Journal of Experimental Medicine (JEM), suggests that protecting these cells by inhibiting a cell death pathway called necroptosis could be a new therapeutic approach to treating IPF.
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Image: close-up of a liver cancer stem-like cell; Copyright: Dr Toh Tan Boon, NUS N.1 Institute for Health

Cells: potential liver cancer treatment

10.10.2019

Liver cancer is the second leading cause of cancer-related deaths worldwide. The most common primary liver cancer in adults is known as hepatocellular carcinoma (HCC), and accounts for approximately 780.000 deaths every year. Even with advanced surgical treatments or transplantation, the 5-year survival rate for HCC patients remains poor due to frequent recurrence.
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Image: model image of pathogens; Copyright: Sebastian Geibel

Pathogens: new insights in tuberculosis

10.10.2019

Researchers at the University of Würzburg and the Spanish Cancer Research Centre have gained new insights into the pathogen that causes tuberculosis. The work published in Nature provides the basis for a new approach in antibiotic therapy.
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Image: ink is applied to a carrier plate with a 3D-Printer; Copyright: Empa

3D-Printing: Wood on our Skin

09.10.2019

Physiological parameters in our blood can be determined without painful punctures. Empa researchers are currently working with a Canadian team to develop flexible, biocompatible nanocellulose sensors that can be attached to the skin. The 3D-printed analytic chips made of renewable raw materials will even be biodegradable in future.
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Image: blood vessel; Copyright: panthermedia.net/thelightwriter

Blood vessels: overly permeable

09.10.2019

In Germany alone there are around 400,000 patients who suffer from chronic inflammatory bowel diseases. For the first time, researchers have discovered that dysfunctions in blood vessels play a significant role in the development of such diseases. In experimental model systems, the progression of the disease slowed down significantly by eliminating these dysfunctions.
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Proliant Acquires Boval Biosolutions

08.10.2019

Proliant Biologicals, LLC (Proliant), an LGI company (Lauridsen Group Inc.), today announced that it has acquired Boval BioSolutions from Lifecycle Biotechnologies of Fort Worth, TX. The acquisition...
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Image: Volker Bruns; Copyright: Fraunhofer ISS

AI software: "iSTIX opens your world to the possibilities of digital pathology"

08.10.2019

The healthcare market offers a multitude of microscopes that make cells visible to the human eye. The same applies to AI-based software for image analysis. After taking the microscopic images, scientist are faced with large volumes of scans with usually low resolution. Yet when all aspects merge together, they open up a the world of digital pathology.
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Image: immunofluorescence of spleen sections of a mice; Copyright: IMP

Pathogens: a mechanism to control autoimmunity

08.10.2019

The immune system relies on B cells and their ability to make antibodies against an extremely broad range of pathogens. This broad responsiveness bears some risk, as B cells can also turn against healthy tissue - a phenomenon called autoimmunity.
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Image: interneuron string on a black background; Copyright: Leonie Pothmann/Uni Bonn

Cells: epilepsy disrupting "brake cells" functions

07.10.2019

In some forms of epilepsy, the function of certain "brake cells" in the brain is presumed to be disrupted. This may be one of the reasons why the electrical malfunction is able to spread from the point of origin across large parts of the brain. A current study by the University of Bonn, in which researchers from Lisbon were also involved, points in this direction.
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Image: cells devouring tumor cells under a microscope; Copyright: Dr Fotini Vogiatzi

Immunotherapy: a promising antibody

07.10.2019

Acute lymphoblastic leukaemia (ALL) is the most common cancer in children. This form of blood cancer is caused by malignant abnormal precursor cells of certain white blood cells, and usually leads to a rapidly progressive reduction of bone marrow function, and thus impaired blood formation.
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Image: scientist researches with light; Copyright: panthermedia.net / lightpoet

Optoceutics: A new technique using light for regenerative medicine

03.10.2019

Using light to facilitate the formation of new blood vessels: it is the breakthrough outcome of a research study carried out by researchers at Istituto Italiano di Tecnologia (IIT) in Milan (Italy). The study was published in Science Advances.
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Image: detail of the microneedle biosensor; Copyright: Imperial College London

Biosensor: detecting patient's antibiotic levels with microneedles

02.10.2019

Small, non-invasive patches worn on the skin can accurately detect the levels of medication in a patient's system, matching the accuracy of current clinical methods. In a small-scale clinical evaluation, researchers at Imperial College London have shown for the first time how microneedle biosensors can be used to monitor the changing concentration of antibiotics.
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Image: Printer head on a solvent-cast 3D printer depositing the functionalized polymer inks layer-by-layer from a needle; Copyright: Lehigh University/Stephanie Veto

Regenerative medicine: biofabrication for multiple tissues

01.10.2019

Organs, muscles and bones are composed of multiple types of cells and tissues that are carefully organized to carry out a specific function. For example, kidneys are able to filter waste from the blood because of how their specialized cells and tissues are arranged. Disrupting this organization dramatically affects how cells and tissues do their job effectively.
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Biochip instead of animal testing - LiquiDoS doses nutrient medium with system

27.09.2019

New active ingredients require new tests. For ethical, economic and scientific reasons, animal experimentations are increasingly being replaced by biochips. Human cells from different organs are...
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Image: Close up of synthetic multiepitope display scaffold; Copyright: University of Bristol

Vaccination: new synthetic vaccines to combat epidemics

26.09.2019

Infectious diseases continue to plague populations worldwide. Among the means at our disposal to counter this threat, vaccination has proven to be exceptionally powerful. A new type of vaccine that can be stored at warmer temperatures, removing the need for refrigeration, has been developed for mosquito-borne virus Chikungunya in a major advance in vaccine technology.
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IVDR-Alliance offers One-Stop-Solution for IVDR-compliance

26.09.2019

The IVD-Alliance is an intitiative to support companies in die IVD-business with knowledge and test equipment to reach the European IVDR-compliance until May 2020. The alliance is a cooperation...
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Image: tissue in a glass container; Copyright: Fraunhofer FEP

Implants: innovative multi-component procedure

25.09.2019

The Fraunhofer FEP has developed a process, called SULEEI, which makes it possible to sterilize and preserve decellularized pericardial tissue by means of photo-initiated ultraviolet crosslinking with low-energy electron irradiation.
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Image: Blood in test tubes; Copyright: panthermedia.net/scanrail

Cells: mechanism for the formation of new blood vessels

24.09.2019

Researchers from Uppsala University have revealed for the first time a mechanism for how new blood vessels are formed and have shown the importance of this mechanism for embryo survival and organ function. The results could be developed to control the formation of new blood vessels in different diseases. The new study is published in the journal EMBO Reports.
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Image: nanomaterial structural image; Copyright: Santos Lab

Nanotechnology: nanomedicine for efficient chemotherapy

23.09.2019

Researchers at the University of Helsinki in collaboration with researchers from Åbo Akademi University,Finland and Huazhong University of Science and Technology,China have developed a new anti-cancer nanomedicine for targeted cancer chemotherapy. This new nano-tool provides a new approach to use cell-based nanomedicines for effcient cancer chemotherapy.
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Image: Illustrated DNA string; Copyright: Yen Strandqvist/Chalmers University of Technology

DNA: held together by hydrophobic forces

23.09.2019

Researchers at Chalmers University of Technology, Sweden, disprove the prevailing theory of how DNA binds itself. It is not, as is generally believed, hydrogen bonds which bind together the two sides of the DNA structure. Instead, water is the key. The discovery opens doors for new understanding in research in medicine and life sciences. The researchers' findings are presented in the journal PNAS.
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Image: Man with mouthguard and laboratory glasses holding Petri dish up; Copyright: panthermedia.net/kasto

Cardiac Tissue Engineering: a heart out of the Petri dish

23.09.2019

For patients waiting for donor organs, every day can mean the difference between life and death. Making things even more complicated is the fact that not every organ is a compatible match with the patient. It would mean enormous progress if we could grow organs from the patient's own cells in the lab. That's why patients with heart disease place big hope in tissue engineering.
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Image: retina layers displayed in a diagram; Copyright: Knowledge Technology Institute, UCM

Retina: areas change in mild Alzheimer's disease

19.09.2019

Researchers at the Complutense University of Madrid (UCM) have identified changes in retinal layer thickness, inflammation or thinning in patients with mild Alzheimer's disease, confirming that the retina is one of the most important biomarkers for early diagnosis of the disease.
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Image: bacterial syringe structure on a black background; Copyright: Shikuma Lab

Bacteriology: structures can be tapped to deliver drugs

19.09.2019

Not all bacteria spread diseases, many are beneficial and this strain has nanoscale syringes that deliver proteins which cause metamorphosis in marine animals, and could be modified as a novel drug delivery tool for future vaccines and cancer care.
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 Image: Research team of nonoparticle sensor; Copyright: Asociación RUVID

Optical sensor: detects very low glucose concentrations

17.09.2019

The Optical Research Group of the Universitat Jaume I has developed an optical nanoparticle sensor capable of detecting very low glucose concentrations, such as those present in a person's tear, by means of fluorescent carbon quantum dots, applying synthesis of nanomaterials based on irradiation with ultra-short lasers, which is an alternative, sustainable and non-polluting method.
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Image: purple microscope image of squamous cell carcinoma of the lung and squamous cell carcinoma of the head and neck; Copyright: Jurmeister/Charité

Machine Learning: improving the diagnosis of head and neck cancers

16.09.2019

Researchers from Charité - Universitätsmedizin Berlin and the German Cancer Consortium have successfully solved a longstanding problem in the diagnosis of head and neck cancers. Working alongside colleagues from TU Berlin, the researchers used artificial intelligence to develop a new classification method which identifies the primary origins of cancerous tissue based on chemical DNA changes.
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Image: high-resolution fluorescence imaging of activated fibroblasts; Copyright: Wang Mao, Duke-NUS Medical School

Genetics: cardiac fibrosis study identifies key proteins

13.09.2019

Using cutting-edge technologies, researchers at Duke-NUS Medical School, Singapore, have developed the first genome-wide dataset on protein translation during fibroblast activation, revealing a network of RNA-binding proteins (RBPs) that play a key role in the formation of disease-causing fibrous tissue in the heart.
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Image: tissue grown on a capillary bridge; Copyright: MPI of Colloids and Interfaces/ Sebastian Ehrig

Tissue engineering: Form is function

12.09.2019

Liquid-like tissue behavior is a key principle for the formation of structures in biological systems. Researchers at the Max Planck Institute of Colloids and Interfaces in Potsdam have shown that growing bone tissue behaves like a viscous liquid on long time scales, thereby accepting forms with minimal surface area.
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Image: fat cells; Copyright: panthermedia.net/sciencepics

Genetics: women's deep belly fat strongly linked to diabetes

12.09.2019

A comprehensive study from Uppsala University, with over 325,000 participants, shows that deep belly fat is a major contributing risk factor for developing diabetes and cardiovascular disease. Moreover, the scientists investigated how our genes affect the accumulation of fat and present a new, simpler method to estimate the amount of deep belly fat.
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Image: dna strings in yellow, blue and red; Copyright: panthermedia.net/khenghotoh

DNA: construction kit replaces expensive antibody medication

11.09.2019

Researchers at KU Leuven in Belgium have developed a technique to make sheep produce new antibodies simply by injecting the DNA building blocks. This approach is much cheaper and more efficient than producing antibodies industrially and administering them afterwards. The study in animals with a similar size as humans brings us a step closer to the clinical use of antibody gene therapy.
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Image: woman sitting down; Copyright: panthermedia.net/photographee

Stem cells: antihistamines can kill leukaemic stem cells

09.09.2019

The IJC Leukaemic Stem Cell research group, led by Ruth M. Risueño, has discovered in preclinical trials that a particular group of antihistamines can kill leukaemic stem cells. This group investigates Acute Myeloid Leukaemia (AML) and the cell population responsible for the disease spreading, persisting, and if it has been treated and overcome, reappear.
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Image: Laboratory situation - Prof. Popp shows a young man a small object in his hand; Copyright: Leibniz-IPHT/Sven Döring

Tumor excision: triple imaging for unique diagnostics

08.08.2019

After their tumor has been removed, some patients have to return to the hospital to undergo surgery again. That's because the tumor was not precisely identified and was subsequently not completely removed. That's both an ethical and financial dilemma. A new surgery-adjacent procedure is designed to rapidly and accurately detect tumors.
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Image: A man is holding a hand full of pill blisters with antibiotics; Copyright: panthermedia.net/alexkalina

Combating antibiotic resistance: One step ahead through technology

01.08.2019

Antibiotic resistance is on the rise in all parts of the world, complicating medical treatment of serious bacterial infections in patients. The World Health Organization estimates that approximately 33,000 people die each year from antibiotic-resistant bacteria in Europe alone. Bacteria that are resistant to multiple or even all known antibiotics pose an ever-increasing threat.
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Image: A lab technician is using a pipette to fill a solution into a petri dish; Copyright: panthermedia.net/Arne Trautmann

Last-resort antibiotics: "We can identify carbapenemases within half an hour"

01.08.2019

Antibiotic resistance is modern medicine's greatest challenge. Some bacteria only respond to a handful of antibiotics, prompting hospitals to spend a lot of time finding an effective drug. That’s why it is critical for physicians to rapidly identify antibiotic resistance to avoid ineffective treatments.
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Image: Two petri dishes with different kinds of agar plates on which bacterial cultures are growing; Copyright: panthermedia.net/photographee.eu

Antibiotic resistance: technical tricks against pathogens

01.08.2019

An untreatable infection is a nightmare for physicians and potentially life-threatening to the patient. Unfortunately, more and more pathogens emerge that are resistant to drugs, especially antibiotics. We need to use our drugs smartly and come up with technical solutions as well to prevent our weapons from blunting in the future.
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Image: A greenly lit laboratory device; Copyright: Sven Döring

Photonics: "We want a rapid and easy method to identify pathogens and antibiotic resistance"

01.08.2019

The medical devices value chain has gaps between academic research and industrial practice that slow down innovation processes. This also applies to time-sensitive and urgently needed products such as rapid diagnostic tests to identify resistant pathogens. At the InfectoGnostics Research Campus in Jena, partners from research and medicine team up to close these gaps.
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Image: Flags; Copyright: SilverSky LifeSciences GmbH

Striking new paths in medicine - Diagnostics Partnering Conference 2019

08.07.2019

On November 18th, 2019, parallel to the first day of MEDICA, the world forum for medicine, the Diagnostics Partnering Conference (DxPx Conference) will take place in Düsseldorf, bringing together stakeholders in the diagnostics and research tool industry. The DxPx Conference focuses on discovering technologies, finding financing and investment opportunities and forming collaborative partnerships.
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Image: Ellipsoid of revolution with a gold coating to detect backscattered photons from the skin tissue; Copyright: Sven Delbeck/Fachhochschule Südwestfalen

Blood Sugar Monitoring: Using Infrared Instead of Invasive Techniques

22.03.2019

Over six million people in Germany have diabetes. It is estimated that almost 400 million people are affected by this disease worldwide. Diabetes sufferers must prick their fingers several times a day to monitor their blood sugar.
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Picture: Woman sleeping sideways in bed with a breathing mask; Copyright: Philips GmbH

Comprehensive Treatment: It’s All About Breathing

01.03.2019

Coughing, airway obstruction, difficulty breathing: Chronic obstructive pulmonary disease (COPD) is an umbrella term used to describe progressive and currently incurable lung diseases. The innovative solutions of Philips Respironics help patients to manage each stage of the disease and their medication intake, train the respiratory system and provide respiratory support.
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Image: Cell cultivation in a Petri dish; Copyright: panthermedia.net / matej kastelic

Organ-on-a-chip – Organs in miniature format

01.02.2019

In vitro processes and animal tests are used to develop new medications and novel therapeutic approaches. However, animal testing raises important ethical concerns. Organ-on-a-chip models promise to be a feasible alternative. In a system the size of a smartphone, organs are connected using artificial circulation.
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Image: Man and woman in a laboratory presenting a multi-organ chip; Copyright: TissUse GmbH

Multi-Organ Chips – The Patients of Tomorrow?

01.02.2019

The liver, nervous tissue or the intestines: all are important human organs that have in the past been tested for their function and compatibility using animal or in vitro test methods. In recent years, TissUse GmbH, a spin-off of the Technical University of Berlin (TU Berlin), has launched multi-organ chip platforms. But that’s not all.
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Image: Graphic rendering of several cells in a petri dish; Copyright: panthermedia.net/dani3315

Organ-on-a-chip systems: limited validity?

01.02.2019

Organ-on-a-chip systems are technically a great enhancement of medical research because they facilitate testing of active ingredients on cell cultures in the chambers of a plastic chip. This replaces animal testing and improves patient safety. That being said, they are not a true-to-life replication of the human body and can only simulate a few functions and activities.
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Image: Cells in a Petri dish; Copyright: panthermedia.net / devserenco

Organ-on-a-chip - the mini organs of the future?

01.02.2019

So far in vitro methods and animal experiments have been used to determine the causes of diseases, research therapeutic approaches and predict the effect of drugs. Organ-on-a-chip models now offer a more accurate and ethically justifiable alternative. Find out more about the models, their advantages and future developments in our Topic of the Month.
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Image: Glucometer next to a smartphone that shows the blood glucose level; Copyright: panthermedia.net/simpson33

DiaDigital: making sense of diabetes apps

02.01.2019

While they are very useful, health apps have one major drawback: anyone can release and distribute them unchecked. Only some apps require medical device certification. So how can users spot a great, safe and useful app? When it comes to diabetes apps, the “DiaDigital” seal of distinction is the answer.
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Image: Woman at the table operating a smartphone and surrounded by utensils for diabetes therapy; Copyright: panthemedia.net/Lev Dolgachov

Diabetes digital – smart support for diabetics

02.01.2019

Monitoring blood sugar levels, counting carbohydrates, calculating insulin doses, and keeping accurate records - diabetes is a data-intensive disease that demands a lot of self-discipline and attention from the patients. Some concerns are patients neglecting to keep a food journal, "fudged" test results or calculation errors. Digital solutions help patients easily manage the large volumes of data.
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Image: digital capture of an eye; Copyright: panthermedia.net / cosmin momir

A digital look inside the human eye – when algorithms diagnose Diabetes

02.01.2019

Diabetes mellitus or simply diabetes has become very common and is often described as a lifestyle disease. More and more people are suffering from this chronic metabolic disorder. Next to established diagnostic procedures, digital retinal screening has shown to be successful - a promising technique that will also play an important role in the diagnosis of other diseases in the future.
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Image: Woman with diabetes and a sensor; Copyright: panthermedia.net / Click and Photo

Blood glucose monitoring of tomorrow - modern diabetes therapies

02.01.2019

There are 425 million people with diabetes in the world. Heart problems, kidney failure or blindness - these can all be consequences of the metabolic disease. Diabetes patients now have the possibility of being treated digitally.
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From algorithm to rapid test – Artificial Intelligence classifies blood cells

21.11.2018

Our blood reveals a lot about our physical health. The shape of our blood cells sheds light on several hereditary diseases for example. For a diagnosis, the cells must first be examined under the microscope and categorized into a specific cell class. We met with Dr. Stephan Quint and Alexander Kihm of the Institute of Physics at the Saarland University, who explained how this classification works.
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Neighbours as guests at MEDICA - Interview at the Polish joint stand

15.11.2018

100 Polish exhibitors will be present at this year's MEDICA and show their new innovations in medical technology. You can find out what there is to discover at the Polish joint stand in our interview.
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Interview with Hombrechtikon Systems Engineering AG

15.11.2018

Whether DNA testing, tissue analysis or blood tests – the secrets of life are unraveled in the laboratory. In order to master this challenge, all processes must first be optimized and automated. Which role HSE AG plays here, the Swiss company explains at MEDICA 2018.
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Interview with ERBA Diagnostics Mannheim GmbH

15.11.2018

A lot of answers in medicine are found in the laboratory. Correct analysis is key to find the right diagnosis and cure for the patient. We learn more about innovative analysis devices at the stand of ERBA Diagnostics at MEDICA 2018.
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Past, present and future of MEDICA – Interview with Horst Giesen

12.11.2018

Even before MEDICA begins, the Düsseldorf trade fair grounds are alive like a beehive: in the halls, stands are built and exhibits are delivered, while the trade fair management coordinates logistics and services for exhibitors and visitors. We were still able to have a short talk to Horst Giesen, Global Portfolio Director Health & Medical Technologies of Messe Düsseldorf, despite all the bustle.
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Diagnostics at record speeds – POCT in high-performance sports

02.11.2018

This is what diagnostic investigation normally looks like: a patient sample is collected, sent to the laboratory and analyzed. Once that's completed, the patient is told of the lab test result. But if the patient is a high-performance athlete and has to follow and stick to a rigid training schedule, he or she needs these results immediately. What makes this possible? Point-of-care testing!
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Image: visitors at MEDICA; Copyright: Messe Düsseldorf

See, experience, learn: what's new at MEDICA 2018

02.11.2018

It's time: the world's largest medical trade fair opens its doors from 12 to 15 November. More than 5,000 international exhibitors will present their new innovative products and applications. Frums, conferences and special shows will feature exciting specialist lectures and discussions that will give you an insight into electromedicine, laboratory medicine, medical technology and diagnostics.
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Image: Maria Driesel and her colleagues from inveox next to the new device; Copyright: Astrid Eckert

Pathology 4.0 – inveox automates laboratory processes

22.08.2018

Mix-ups, contamination and sample loss – most errors in pathology happen when specimen are received. Countless samples arrive daily at the laboratory, while the sample entry process is very monotonous. As a result, the work is inefficient. The start-up company inveox has now developed a system that automates the processes in the pathology laboratory, thus making them more efficient.
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Image: Small brown mole on the back of a hand; Copyright: panthermedia.net/Mario Hahn

Early detection: Tattoo signals cancer – and more

09.07.2018

People who are not ill and do not show any symptoms typically do not visit the doctor. And while most people know that preventive medical checkups for cancer, for example, are important, they still avoid them. They tend to be very hesitant because the doctor might detect a serious illness. In the future, a new type of implant could make it easier to go to a screening test.
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Image: AcCellerator research device at an exhibition stand; Copyright: Daniel Klaue, ZELLMECHANIK DRESDEN GmbH

Cells in the speed trap – diagnosis in a matter of seconds

22.06.2018

A drop of blood provides a lot of valuable information. However, it takes several hours to analyze the blood of a patient and make a diagnosis. This takes away a lot of time that's crucial for treatment. A new method intends to considerably speed up this process by testing the cells in the blood in terms of their deformability and immune response.
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Personalized cancer medicine – Best possible treatment with TherapySelect

30.04.2018

Medicine is getting more and more personalized. This is particularly interesting for oncology, since a cancer is as individual as the respective patient. When choosing a therapy, both the characteristics of the tumor and the personal characteristics of the patient must be considered. To see exactly what this looks like, we visited the diagnostics company TherapySelect, based in Heidelberg.
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Image: Two hands are holding a tubular frame that is carrying a glistening wet, white tube; Copyright: Leibniz University of Hanover/Institute of Technical Chemistry

Tissue engineering: how to grow a bypass

23.04.2018

A bypass is a complicated structure. It is either made of synthetic materials that can cause blood clots and infections or created by using the patient’s veins. However, the latter often does not yield adequate material. A newly developed bioreactor could solve this problem in the future. It is designed to tissue engineer vascular grafts by using the body’s own material.
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Image: Three men in suits and a woman in a laboratory coat are standing in a laboratory; Copyright: Ministry of Economy of Mecklenburg-Hither Pomerania/Norbert Fellechner

On the trail of cancer: personalized cancer vaccine

01.03.2018

Conventional cancer treatment selection typically depends on the location of the tumor. However, this approach ignores the distinct gene mutations in the tumor of the individual patient. New cancer research approaches increasingly emphasize the concept of personalized therapy.
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Image: Several colorful pills placed on a target, one of them is in the center; Copyright: panthermedia.net/georgemuresan

Personalized Medicine – focused on healing

01.03.2018

Personalized medicine does not want to measure all patients with the same yardstick anymore. Instead, it aims to precisely fit the therapy to the cause of their disease. This often means a more successful treatment with less side effects for patients. And for physicians, interdisciplinary cooperation and decision making come to the fore.
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Image: A group of physicians is holding large colorful puzzle pieces in their hands and is putting them together; Copyright: panthermedia.net/Andriy Popov

Personalized medicine: a paradigm shift is gaining momentum

01.03.2018

Personalized medicine does not follow a "one-size-fits-all" treatment approach but emphasizes a "tailor-made" paradigm, meaning a treatment is customized to each individual person's case. For patients, this increases the chances of treatment success and means fewer side effects. While the approach originates in the field of oncology, it is now also increasingly applied to other disease patterns.
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Image: yellow tape measure with capsules in front of it; Copyright: panthermedia.net/Jiri Hera

Personalized cancer medicine: customized treatment

01.03.2018

Everyone is different. This statement also applies to our health. Cancer, in particular, can look and progress differently depending on the individual person. That’s why every patient ideally also needs a customized treatment that is tailored to their individual needs. But how feasible is this idea?
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Image: a container with the nutrient medium for cancer cells; Copyright: Dr. Markus Wehland

Cells in space – extraterrestrial approaches in cancer research

22.02.2018

Here on Earth, all experiments are bound by gravitation. Yet, freed from gravity's grip, tumor cells, for example, behave in an entirely different way. As part of the "Thyroid Cancer Cells in Space" project by the University of Magdeburg, smartphone-sized containers carrying poorly differentiated thyroid cancer cells are sent into space.
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"Spray-On" muscle fibers for biomimetic surfaces

08.01.2018

Few patients with heart failure are fortunate enough to receive a donor's heart. Ventricular assist devices (or heart pumps) have been around for several years and are designed to buy time as patients wait for a transplant. Unfortunately, the body doesn't always tolerate these devices.
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Health-i Award: The best ideas for the health of tomorrow

15.11.2017

The digitalisation of the health care system is making great strides forward. In order to give further impetus to this trend, the Health-i Award brings together experts from business, science and health. In the MEDICA ECON FORUM by TK three promising start-ups were presented.
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The MEDICA START-UP PARK: spotlight on young companies

14.11.2017

What's UP? This year, a piece of the future of digital health is shown for the first time in the MEDICA START-UP PARK. Here, young companies can present themselves and establish the contacts they need in the world of medicine to promote their innovations.
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Research and diagnostics – laboratory technology at MEDICA 2017

14.11.2017

Whether analysis, evaluation or preparation of samples – the laboratory is the core of every research institute. The work’s efficiency also depends to a large extent on the equipment and items. You can discover the latest trends and developments in laboratory technology at MEDICA 2017. See for yourself!
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Three proofs in one go - Interview with Genekam Biotechnology AG

13.11.2017

Measles, mumps and rubella are usually mentioned in connection with the well-known polyvalent vaccine. Now, a novel DNA test can be used to remedy an unclear situation about an infection. It is supposed to detect all three diseases in just one step. Find out more in our interview with Genekam Biotechnology AG at MEDICA 2017.
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MEDICA 2017: Cutting-edge, look into the future

13.11.2017

For exhibitors and visitors, MEDICA 2017 does not start until Monday. However, the trade press already gets a preview of some selected product highlights on the Sunday before the trade fair. We were there with the camera and met with some exhibitors. They gave us the opportunity to present cutting-edge products and to take a look at the medical technology of the future.
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Image: Surgeons during surgery; Copyright: UKR

Acute kidney injury: Early detection thanks to biomarker

08.11.2017

Major surgeries in the abdominal region often result in kidney injury in patients. Meanwhile, the clinical manifestations don't present until one or two days after the procedure. This causes physicians to lose valuable time to treat patients. The University Hospital Regensburg has researched a new concept for the treatment of kidney injuries for several years.
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A look at the medicine of tomorrow – At MEDICA Preview in Hamburg

08.11.2017

Every year in September, MEDICA Preview takes place at the University Hospital Hamburg-Eppendorf. It is intended to give visitors, exhibitors and the trade press a foretaste of MEDICA in November and tomorrow's medicine. This year, we were on the scene with our camera to learn more about opto genetics, smart hospitals and the support of patients with multiple organ failure.
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Image: Three-dimensional image of a colored vessel structure; Copyright: René Hägerling

Pathology: detecting lymphedema with 3D microscopy

23.10.2017

According to the WHO, 300 million people throughout the world are affected by lymphedema. This condition occurs when fluid that flows between cells is no longer transported back into the blood circulation and accumulates in the skin. Triggers can be surgeries, injuries or genetic defects for example. A new microscopy technique could now also indicate the causes.
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Point-of-care testing in the hospital – quality diagnostic results

18.10.2017

Point-of-care testing is an integral part of medicine. It enables simple, automated testing that yields fast results. Hospitals have also started to increasingly use POCT diagnostic systems over the past few years. We are guests at the Greifswald University Hospital where patient-side rapid diagnostic tests have already been successfully integrated into daily hospital operations.
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Image: Vials in a rack; Copyright: Messe Düsseldorf

MEDICA 2017: all about laboratory medicine at the MEDICA LABMED FORUM

02.10.2017

If you are interested in laboratory medicine and come to the MEDICA 2017, you will quickly notice that Exhibition Halls 1 and 2 were demolished. A new state-of-the art hall is meant to take their place. Until then, exhibitors from the field of laboratory medicine will be showcased at their temporary new location in the lightweight hall structures 3a and 18 on the fairgrounds.
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Image: A man is working at a laboratory bench, his screen is showing a program that recognizes his gestures; Copyright: Fraunhofer IPA/Heike Quosdorf

Laboratory automation: from note book to gesture recognition

08.08.2017

For centuries, scientific research has succeeded by chronicling experiments with pinpoint accuracy. Yet despite all the progress in the actual laboratory, recording is often still done manually, in notebooks, logs or computer systems for instance. In the future, a gesture recognition system could perform this task for scientists.
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Image: woman holding a sketch of a human lung; Copyright: panthermedia.net/Monkeybusiness

Molecular Microsystems: Preventing Exacerbations of Asthma and COPD

01.08.2017

An increasing percentage of the world population suffers from chronic inflammatory disorders of the respiratory system. Acute attacks often lead to a worsening of the disease and considerably reduce the patient’s lung volume. Nine institutes of a research alliance under the Leibniz Institute umbrella are working on technologies designed to predict and thus prevent exacerbations.
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Image: A negative rapid test lying on a sheet of paper; Copyright: panthermedia.net/thegoatman

Point-of-care solutions – uncomplicated and fast

01.08.2017

Point-of-Care solutions are medical rapid tests, which can be carried out in an uncomplicated way in nearly any place and without requiring a lot of time. The samples do not have to be sent to a laboratory but can be analyzed in a hospital, at the doctor's or at the pharmacist's.
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Image: POCT-device and patient files; Copyright: panthermedia.net/gabriella

Point-of-care testing: helpful when things need to happen quickly?

01.08.2017

Advances in technology and analysis techniques, as well as the increasing miniaturization of laboratory equipment and processes, make it possible: patient-side laboratory testing, better known as point-of-care testing or POCT. There are many POCT projects and all of them promise a rapid diagnosis as well as economic advantages. But are these tests also suited for everyday medical testing?
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Image: blood is taken from a finger and analysed by a blood testing device; Copyright:hes_so_valais_wallis

Without any delay: drug dose adjustment at the point of care

01.08.2017

Many therapeutic drugs are very powerful, but they are also very toxic at the same time. Thus, they have to be measured regularly, again and again, so that an adjustment of the individual drug dosage can be made. Until now, the "normal" way was to take the blood sample, send it to a central laboratory and get the results after some days. A new point-of-care test can measure it in 15 minutes.
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Image: Collage made of two images, one show a round, transparent plastic disc with micro channels, one shows a plastic chip; Copyright: Hahn-Schickard, Image Bernd Müller

Prenatal diagnosis: genetic analysis using droplet PCR

24.07.2017

A new analysis method that uses fetal DNA extracted from the mother’s blood is designed to non-invasively reach a prenatal diagnosis of genetic disorders in a child. A task force of the Hahn Schickard Society for Applied Research is an active part of the "ANGELab" project and co-developed this diagnostic procedure.
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Light microscope ChipScope - a glimpse into living cells

14.07.2017

A microscope that is only a few millimeters in size and that can help to consider cell changes in real time. This is the goal of the EU project ChipScope. Scientists led by Dr. Hutomo Wasisto in Braunschweig help to make this project come true.
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Image: Demonstrator; Copyright: Leibniz-IPHT

Medical imaging is onto septic fungi

03.04.2017

Instant treatment is absolute vital for patients developing sepsis. Providing a specific therapy early on is key. To manage this the pathogenic organisms need to be identified accurately. But a fungal sepsis can still be a hard nut to crack.
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Image: Graphic representation of Europe with small figures depicting the population; Copyright: panthermedia.net/Takahase Segundo

Hospital-acquired infections: pathogens know no borders

03.04.2017

Many aspects are uniformly regulated in Europe, however, hospital hygiene and MRSA prevention, for example, are not. The Netherlands plays a pioneering role in the fight against hospital-acquired infections. The country is an often-cited role model. But can other countries simply adopt the same system? And what makes it so different? MEDICA asked expert Prof. Alexander W. Friedrich.
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Image: Three young female scientists work together in a laboratory; Copyright: panthermedia.net/Viktor Cap

Infectious diseases – the laboratory races pathogens

03.04.2017

Infectious diseases come unnoticed and can have severe consequences. Prevention through good hygiene is the best protection for people in hospitals. This is especially necessary for weakened patients whose immune systems are not able to fight back the infections by themselves. When they still fall ill, physicians need to be quick to diagnose and treat them.
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Image: A petri dish with yellow bacterial cultures on a black ground; Copyright: panthermedia.net/kwanchaichaiudom

Laboratory medicine: confronting infections with speed and foresight

03.04.2017

The laboratory is one of the most important and pivotal bastions in patient care. In the laboratory, acute, chronic and genetic diseases are diagnosed, the progression of diseases such as diabetes is regularly checked or specialists look for biomarkers to adapt cancer therapies.
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