24.06.2019A team of researchers from Jena is presenting a groundbreaking new method for the rapid, gentle and reliable detection of tumors with laser light. For the first time, the Leibniz IPHT will present a compact device for rapid cancer diagnosis during surgery. The optical method will help surgeons to remove tumors more precisely and could make cancer operations possible without a scalpel.
21.06.2019Investigators from Brigham and Women's Hospital are taking advantage of a unique phenomenon of nanoparticles to develop a test for early detection of different types of diseases, including cancer.
19.06.2019Scientists in Japan have developed a way of amplifying DNA on a scale suitable for use in the emerging fields of DNA-based computing and molecular robotics. By enabling highly sensitive nucleic acid detection, their method could improve disease diagnostics and accelerate the development of biosensors, for example, for food and environmental applications.
19.06.2019Sickle cell disease is a hereditary disorder that affects red blood cells, distorting their natural disc shape into a crescent moon or "sickle" shape. Normal red blood cells move freely through small vessels throughout the body to deliver oxygen. With sickle cell disease, the misshapen red blood cells become hard and sticky, making it difficult for them to move through blood vessels.
18.06.2019Researchers at Ben-Gurion University of the Negev (BGU) and Cedars-Sinai Medical Center in Los Angeles have, for the first time, duplicated a patient's blood-brain barrier (BBB), creating a human BBB chip with stem cells, which can be used to develop personalized medicine and new techniques to research brain disorders.
17.06.2019Like airport security barriers that either clear authorized travelers or block unauthorized travelers and their luggage from accessing central operation areas, the blood-brain-barrier (BBB) tightly controls the transport of essential nutrients and energy metabolites into the brain and staves off unwanted substances circulating in the blood stream.
17.06.2019A combined research team from Carnegie Mellon University and Benaroya Research Institute at Virginia Mason is pairing a nanoscale imaging technique with virtual reality (VR) technology to create a method that allows researchers to "step inside" their biological data.
13.06.2019A discovery by researchers at the School of Life Sciences at the University of Warwick offers a new technology for detecting bacteria in minutes by `zapping` the bacteria with electricity.
10.06.2019Combining tissue imaging and artificial intelligence, Hollings Cancer Center researchers at the Medical University of South Carolina probed deeper into how cell division cycles are regulated, in this study released online in the May 2019 issue of Cell Reports.
10.06.2019Cysts in the pancreas sometimes develop into the invasive cancer, depending on the type of cyst, but such growths often are not cancerous, creating a quandary for physicians who spot them via CT and MRI scans. Surgery to remove pancreatic cysts is often complex, so there is a need for new tools to identify which such cysts are most likely to develop into cancer and which are not.
07.06.2019Researchers from The Westmead Institute for Medical Research have developed a standardized method of measuring the immune response in islet transplant recipients, helping predict patient outcomes.
05.06.2019Diseases caused by genetic changes could be detected more readily thanks to an advance in DNA analysis software. The development will make it easier to integrate genetic testing into health care systems such as the UK's National Health Service, which cares for around three million people affected by genetic diseases in the UK.
04.06.2019Scientists successfully bioengineered human liver organoids that faithfully mimic key features of fatal liver disease in the laboratory. This allowed them to uncover underlying disease biology in the organoids and test a potential therapy that in preclinical lab tests reversed an often-fatal childhood condition called Wolman disease.
31.05.2019Adrenomedullin activity predicts which acute heart failure patients are at the greatest risk of death without diuretic treatment post-discharge, according to late breaking research presented today at Heart Failure 2019, a scientific congress of the European Society of Cardiology (ESC).
29.05.2019Stress is often called "the silent killer" because of its stealthy and mysterious effects on everything from heart disease to mental health. Now researchers at the University of Cincinnati have developed a new test that can easily and simply measure common stress hormones using sweat, blood, urine or saliva.
28.05.2019The production of artificial organs is a hot research topic. In the near future, artificial organs will compensate for the lack of organ donations and replace animal experiments. Although there are already promising experiments with 3D printers that use a "bio-ink" containing living cells, a functional organ has never been created in this way.
27.05.2019Alzheimer's disease is the major cause of dementia and so far, no effective treatment can prevent, delay or stop its progression. We know that AD has an extensive prodromal stage (with initial symptoms preceding the disease) which lasts 15 to 20 years before clinical signs are evident. To envision an effective treatment for AD, we need to be able to accurately diagnose AD at its earliest stages.
24.05.2019University of Maryland School of Medicine study shows the potential of transplanted stem cell secretions as a liquid biopsy.
24.05.2019Prostate cancer is the second-leading cause of male cancer deaths worldwide. Deaths from prostate cancer are primarily due to metastasized cancer, in which cancer cells have migrated through the body and begun to grow in other areas. Results reported in Biomicrofluidics, from AIP Publishing, promise a new way to detect this deadly disease through a simple, inexpensive device.
23.05.2019UNIGE researchers have developed a cell co-culture platform that can reproduce a patient's tumour in 3D and test the best treatment combinations for its specific case in just five days.
22.05.2019The search for new drugs to combat diseases more effectively could be revolutionised through a new £30 million electron microscopy project. Experts would be able to see, for the first time, how a particular drug works within a patient at a cellular level or the molecular processes set in motion by a genetic mutation.
20.05.2019Instead of searching for a needle in a haystack, what if you were able to sweep the entire haystack to one side, leaving only the needle behind? That's the strategy researchers in the University of Georgia College of Engineering followed in developing a new microfluidic device that separates elusive circulating tumor cells (CTCs) from a sample of whole blood.
15.05.2019New active substances that are suitable for drugs are initially tested in animal experiments. However, the results cannot always be transferred to the human organism. At the Karlsruhe Institute of Technology, Prof. Ute Schepers from vasQlab explains how active substances can be tested in human tissue without endangering human health.
14.05.2019Data-sampling method makes "sketches" of unwieldy biological datasets while still capturing the full diversity of cell types. MIT researchers are now bringing that concept to computational biology, with a novel method that extracts comprehensive samples of massive cell datasets that are easier to analyze for biological and medical studies.
13.05.2019Presently there are no disease-modifying therapies for the treatment of Parkinson’s disease; however, one potential strategy for treatment is to prevent α-synuclein aggregation. As a first step, researchers at Osaka University have developed a device that can assess the degree of α-synuclein aggregation in the brain.
10.05.2019A simple innovation the size of a grain of sand means we can now analyse cells and tiny particles as if they were inside the human body. The new micro-device for fluid analysis will enable more tailored experiments in drug development and disease research via new 'organ-on-chip' systems.
07.05.2019Advancing technology is allowing scientists increasingly to search for tiny signs of cancer and other health issues in samples of patients' blood and urine. These "liquid biopsies" are less invasive than a traditional biopsy, and can provide information about what's happening throughout the body instead of just at a single site.
06.05.2019To model human health and disease, organ-on-a-chip technology mimics the human body's organ structure, functionality and physiology in a controlled environment. These miniature systems, which serve as accurate models of various organs from the heart and lungs to the gut and the kidneys, can use a patient's own cells to test drugs and understand disease processes.
06.05.2019A faculty-researcher at Rochester Institute of technology has developed a prototype micro device with bio-sensors that can detect the deadly Ebola virus. With this type of device, those infected can be treated earlier, and the early detection process can potentially decrease the spread of infections.
03.05.2019Renalytix AI plc (AIM: RENX), a developer of artificial intelligence-enabled clinical diagnostics for kidney disease, announces that it has been granted Breakthrough Device designation by the U.S. Food and Drug Administration (FDA), for its lead diagnostic, KidneyIntelX™. This is the first such designation for an AI-enabled diagnostic for kidney disease publicly announced by any company.
30.04.2019A breast cancer test has been found that helps doctors make treatment decisions for some breast cancer patients, following research carried out at Queen Mary University of London and funded by Cancer Research UK.
26.04.2019The Fraunhofer Institute for Production Technology IPT in Aachen has developed a high-speed microscope for quality control of large-area objects for the semiconductor and electronics industries or for rapid testing of biological samples.
26.04.2019Columbia engineers develop a new platform that recreates cancer in a dish to quickly determine the best bacterial therapy.
25.04.2019Like other biofluids, sweat contains a wealth of information about what's going on inside the body. However, collecting the fluid for analysis, usually by dripping or absorbing it from the skin's surface, can be time-consuming and messy.
24.04.2019A new computational approach has been developed to reduce variability in common research biomarker tests, a promising step in improving the ability of biomedical researchers and basic scientists to reproduce data and facilitate more consistent results across laboratories and long-term projects.
23.04.2019They are working in the background, but the things they do often decide about the right therapy or can even be life savers: labs and laboratory technology are probably the most important part of today’s medicine. This is why World Laboratory Day aims to draw attention to this "hidden" part of medicine.
19.04.2019In order to understand the brain, scientists must be able to see the brain--cell by cell, and moment by moment. However, because brains comprise billions of microscopic moving parts, faithfully recording their activity comes with many challenges.
18.04.2019Biotechnologists, physicists, and medical researchers at Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU) have developed technology for microscopic imaging in living organisms.
17.04.2019An international team of scientists has mapped a molecular complex that could aid in the development of better medications with fewer side effects for osteoporosis and cancer.
17.04.2019Lensless microscopy with X-rays, or coherent diffractive imaging, is a promising approach. It allows researchers to analyse complex three-dimensional structures, which frequently exist in nature, from a dynamic perspective.
16.04.2019Experimental molecular assays with single-cell resolution generate big and complex data. Researchers at Helmholtz Zentrum München and the Technical University of Munich are now presenting their computer algorithm PAGA.
16.04.2019Biomedical engineers at Duke University have developed an automated process that can trace the shapes of active neurons as accurately as human researchers can, but in a fraction of the time.
12.04.2019North Carolina State University researchers have developed a technique to improve the characteristics of engineered tissues by using ultrasound to align living cells during the biofabrication process.
09.04.2019A team of Colorado State University researchers has developed technology that can detect extremely small amounts of antibodies in a person's blood. Antibodies develop to infect cells or kill pathogens, essentially fighting off a bacteria or virus. The levels of antibodies in the blood can tell whether that person is sick.
03.04.2019From birth through to death, cells lead an eventful existence. Thanks to single-cell genomics, their destiny can be analyzed. But this method destroys the cell. In order to address this problem, researchers at the Helmholtz Zentrum München and the University of Massachusetts use pseudodynamics, a mathematical model that estimates developmental processes from single-cell time series observations.
02.04.2019A prototype wearable device, tested in animal models, can continuously collect live cancer cells directly from a patient's blood. The device developed by a team of engineers and doctors at the University of Michigan could help doctors diagnose and treat cancer more effectively.
01.04.2019A research team led by biophysical chemist Professor Edward Lemke has engineered a designer organelle in a living mammalian cell in a new complex biological translation process. The created membraneless organelle can build proteins from natural and synthetic amino acids carrying new functionalities.
01.04.2019High-resolution optical microscopy methods promise breakthroughs in materials science, biology, and medicine. Today, their possibilities basically reach those of scanning electron microscopy.
29.03.2019Experimenting with mice, Johns Hopkins researchers report they have successfully used positron emission tomography (PET) scans to calculate in real time how much of an immunotherapy drug reaches a tumor and what parts of a cancer remain unaffected.
22.03.2019Over six million people in Germany have diabetes. It is estimated that almost 400 million people are affected by this disease worldwide. Diabetes sufferers must prick their fingers several times a day to monitor their blood sugar.
01.03.2019Coughing, airway obstruction, difficulty breathing: Chronic obstructive pulmonary disease (COPD) is an umbrella term used to describe progressive and currently incurable lung diseases. The innovative solutions of Philips Respironics help patients to manage each stage of the disease and their medication intake, train the respiratory system and provide respiratory support.
01.02.2019In vitro processes and animal tests are used to develop new medications and novel therapeutic approaches. However, animal testing raises important ethical concerns. Organ-on-a-chip models promise to be a feasible alternative. In a system the size of a smartphone, organs are connected using artificial circulation.
01.02.2019The liver, nervous tissue or the intestines: all are important human organs that have in the past been tested for their function and compatibility using animal or in vitro test methods. In recent years, TissUse GmbH, a spin-off of the Technical University of Berlin (TU Berlin), has launched multi-organ chip platforms. But that’s not all.
01.02.2019Organ-on-a-chip systems are technically a great enhancement of medical research because they facilitate testing of active ingredients on cell cultures in the chambers of a plastic chip. This replaces animal testing and improves patient safety. That being said, they are not a true-to-life replication of the human body and can only simulate a few functions and activities.
01.02.2019So far in vitro methods and animal experiments have been used to determine the causes of diseases, research therapeutic approaches and predict the effect of drugs. Organ-on-a-chip models now offer a more accurate and ethically justifiable alternative. Find out more about the models, their advantages and future developments in our Topic of the Month.
02.01.2019While they are very useful, health apps have one major drawback: anyone can release and distribute them unchecked. Only some apps require medical device certification. So how can users spot a great, safe and useful app? When it comes to diabetes apps, the “DiaDigital” seal of distinction is the answer.
02.01.2019Monitoring blood sugar levels, counting carbohydrates, calculating insulin doses, and keeping accurate records - diabetes is a data-intensive disease that demands a lot of self-discipline and attention from the patients. Some concerns are patients neglecting to keep a food journal, "fudged" test results or calculation errors. Digital solutions help patients easily manage the large volumes of data.
02.01.2019Diabetes mellitus or simply diabetes has become very common and is often described as a lifestyle disease. More and more people are suffering from this chronic metabolic disorder. Next to established diagnostic procedures, digital retinal screening has shown to be successful - a promising technique that will also play an important role in the diagnosis of other diseases in the future.
02.01.2019There are 425 million people with diabetes in the world. Heart problems, kidney failure or blindness - these can all be consequences of the metabolic disease. Diabetes patients now have the possibility of being treated digitally.
21.11.2018Our blood reveals a lot about our physical health. The shape of our blood cells sheds light on several hereditary diseases for example. For a diagnosis, the cells must first be examined under the microscope and categorized into a specific cell class. We met with Dr. Stephan Quint and Alexander Kihm of the Institute of Physics at the Saarland University, who explained how this classification works.
15.11.2018100 Polish exhibitors will be present at this year's MEDICA and show their new innovations in medical technology. You can find out what there is to discover at the Polish joint stand in our interview.
15.11.2018Whether DNA testing, tissue analysis or blood tests – the secrets of life are unraveled in the laboratory. In order to master this challenge, all processes must first be optimized and automated. Which role HSE AG plays here, the Swiss company explains at MEDICA 2018.
15.11.2018A lot of answers in medicine are found in the laboratory. Correct analysis is key to find the right diagnosis and cure for the patient. We learn more about innovative analysis devices at the stand of ERBA Diagnostics at MEDICA 2018.
12.11.2018Even before MEDICA begins, the Düsseldorf trade fair grounds are alive like a beehive: in the halls, stands are built and exhibits are delivered, while the trade fair management coordinates logistics and services for exhibitors and visitors. We were still able to have a short talk to Horst Giesen, Global Portfolio Director Health & Medical Technologies of Messe Düsseldorf, despite all the bustle.
02.11.2018This is what diagnostic investigation normally looks like: a patient sample is collected, sent to the laboratory and analyzed. Once that's completed, the patient is told of the lab test result. But if the patient is a high-performance athlete and has to follow and stick to a rigid training schedule, he or she needs these results immediately. What makes this possible? Point-of-care testing!
02.11.2018It's time: the world's largest medical trade fair opens its doors from 12 to 15 November. More than 5,000 international exhibitors will present their new innovative products and applications. Frums, conferences and special shows will feature exciting specialist lectures and discussions that will give you an insight into electromedicine, laboratory medicine, medical technology and diagnostics.
22.08.2018Mix-ups, contamination and sample loss – most errors in pathology happen when specimen are received. Countless samples arrive daily at the laboratory, while the sample entry process is very monotonous. As a result, the work is inefficient. The start-up company inveox has now developed a system that automates the processes in the pathology laboratory, thus making them more efficient.
09.07.2018People who are not ill and do not show any symptoms typically do not visit the doctor. And while most people know that preventive medical checkups for cancer, for example, are important, they still avoid them. They tend to be very hesitant because the doctor might detect a serious illness. In the future, a new type of implant could make it easier to go to a screening test.
22.06.2018A drop of blood provides a lot of valuable information. However, it takes several hours to analyze the blood of a patient and make a diagnosis. This takes away a lot of time that's crucial for treatment. A new method intends to considerably speed up this process by testing the cells in the blood in terms of their deformability and immune response.
30.04.2018Medicine is getting more and more personalized. This is particularly interesting for oncology, since a cancer is as individual as the respective patient. When choosing a therapy, both the characteristics of the tumor and the personal characteristics of the patient must be considered. To see exactly what this looks like, we visited the diagnostics company TherapySelect, based in Heidelberg.
23.04.2018A bypass is a complicated structure. It is either made of synthetic materials that can cause blood clots and infections or created by using the patient’s veins. However, the latter often does not yield adequate material. A newly developed bioreactor could solve this problem in the future. It is designed to tissue engineer vascular grafts by using the body’s own material.
01.03.2018Conventional cancer treatment selection typically depends on the location of the tumor. However, this approach ignores the distinct gene mutations in the tumor of the individual patient. New cancer research approaches increasingly emphasize the concept of personalized therapy.
01.03.2018Personalized medicine does not want to measure all patients with the same yardstick anymore. Instead, it aims to precisely fit the therapy to the cause of their disease. This often means a more successful treatment with less side effects for patients. And for physicians, interdisciplinary cooperation and decision making come to the fore.
01.03.2018Personalized medicine does not follow a "one-size-fits-all" treatment approach but emphasizes a "tailor-made" paradigm, meaning a treatment is customized to each individual person's case. For patients, this increases the chances of treatment success and means fewer side effects. While the approach originates in the field of oncology, it is now also increasingly applied to other disease patterns.
01.03.2018Everyone is different. This statement also applies to our health. Cancer, in particular, can look and progress differently depending on the individual person. That’s why every patient ideally also needs a customized treatment that is tailored to their individual needs. But how feasible is this idea?
22.02.2018Here on Earth, all experiments are bound by gravitation. Yet, freed from gravity's grip, tumor cells, for example, behave in an entirely different way. As part of the "Thyroid Cancer Cells in Space" project by the University of Magdeburg, smartphone-sized containers carrying poorly differentiated thyroid cancer cells are sent into space.
08.01.2018Few patients with heart failure are fortunate enough to receive a donor's heart. Ventricular assist devices (or heart pumps) have been around for several years and are designed to buy time as patients wait for a transplant. Unfortunately, the body doesn't always tolerate these devices.
15.11.2017The digitalisation of the health care system is making great strides forward. In order to give further impetus to this trend, the Health-i Award brings together experts from business, science and health. In the MEDICA ECON FORUM by TK three promising start-ups were presented.
14.11.2017What's UP? This year, a piece of the future of digital health is shown for the first time in the MEDICA START-UP PARK. Here, young companies can present themselves and establish the contacts they need in the world of medicine to promote their innovations.
14.11.2017Whether analysis, evaluation or preparation of samples – the laboratory is the core of every research institute. The work’s efficiency also depends to a large extent on the equipment and items. You can discover the latest trends and developments in laboratory technology at MEDICA 2017. See for yourself!
13.11.2017Measles, mumps and rubella are usually mentioned in connection with the well-known polyvalent vaccine. Now, a novel DNA test can be used to remedy an unclear situation about an infection. It is supposed to detect all three diseases in just one step. Find out more in our interview with Genekam Biotechnology AG at MEDICA 2017.
13.11.2017For exhibitors and visitors, MEDICA 2017 does not start until Monday. However, the trade press already gets a preview of some selected product highlights on the Sunday before the trade fair. We were there with the camera and met with some exhibitors. They gave us the opportunity to present cutting-edge products and to take a look at the medical technology of the future.
08.11.2017Major surgeries in the abdominal region often result in kidney injury in patients. Meanwhile, the clinical manifestations don't present until one or two days after the procedure. This causes physicians to lose valuable time to treat patients. The University Hospital Regensburg has researched a new concept for the treatment of kidney injuries for several years.
08.11.2017Every year in September, MEDICA Preview takes place at the University Hospital Hamburg-Eppendorf. It is intended to give visitors, exhibitors and the trade press a foretaste of MEDICA in November and tomorrow's medicine. This year, we were on the scene with our camera to learn more about opto genetics, smart hospitals and the support of patients with multiple organ failure.
23.10.2017According to the WHO, 300 million people throughout the world are affected by lymphedema. This condition occurs when fluid that flows between cells is no longer transported back into the blood circulation and accumulates in the skin. Triggers can be surgeries, injuries or genetic defects for example. A new microscopy technique could now also indicate the causes.
18.10.2017Point-of-care testing is an integral part of medicine. It enables simple, automated testing that yields fast results. Hospitals have also started to increasingly use POCT diagnostic systems over the past few years. We are guests at the Greifswald University Hospital where patient-side rapid diagnostic tests have already been successfully integrated into daily hospital operations.
02.10.2017If you are interested in laboratory medicine and come to the MEDICA 2017, you will quickly notice that Exhibition Halls 1 and 2 were demolished. A new state-of-the art hall is meant to take their place. Until then, exhibitors from the field of laboratory medicine will be showcased at their temporary new location in the lightweight hall structures 3a and 18 on the fairgrounds.
08.08.2017For centuries, scientific research has succeeded by chronicling experiments with pinpoint accuracy. Yet despite all the progress in the actual laboratory, recording is often still done manually, in notebooks, logs or computer systems for instance. In the future, a gesture recognition system could perform this task for scientists.
01.08.2017An increasing percentage of the world population suffers from chronic inflammatory disorders of the respiratory system. Acute attacks often lead to a worsening of the disease and considerably reduce the patient’s lung volume. Nine institutes of a research alliance under the Leibniz Institute umbrella are working on technologies designed to predict and thus prevent exacerbations.
01.08.2017Point-of-Care solutions are medical rapid tests, which can be carried out in an uncomplicated way in nearly any place and without requiring a lot of time. The samples do not have to be sent to a laboratory but can be analyzed in a hospital, at the doctor's or at the pharmacist's.
01.08.2017Advances in technology and analysis techniques, as well as the increasing miniaturization of laboratory equipment and processes, make it possible: patient-side laboratory testing, better known as point-of-care testing or POCT. There are many POCT projects and all of them promise a rapid diagnosis as well as economic advantages. But are these tests also suited for everyday medical testing?
01.08.2017Many therapeutic drugs are very powerful, but they are also very toxic at the same time. Thus, they have to be measured regularly, again and again, so that an adjustment of the individual drug dosage can be made. Until now, the "normal" way was to take the blood sample, send it to a central laboratory and get the results after some days. A new point-of-care test can measure it in 15 minutes.
24.07.2017A new analysis method that uses fetal DNA extracted from the mother’s blood is designed to non-invasively reach a prenatal diagnosis of genetic disorders in a child. A task force of the Hahn Schickard Society for Applied Research is an active part of the "ANGELab" project and co-developed this diagnostic procedure.
14.07.2017A microscope that is only a few millimeters in size and that can help to consider cell changes in real time. This is the goal of the EU project ChipScope. Scientists led by Dr. Hutomo Wasisto in Braunschweig help to make this project come true.
03.04.2017Instant treatment is absolute vital for patients developing sepsis. Providing a specific therapy early on is key. To manage this the pathogenic organisms need to be identified accurately. But a fungal sepsis can still be a hard nut to crack.
03.04.2017Many aspects are uniformly regulated in Europe, however, hospital hygiene and MRSA prevention, for example, are not. The Netherlands plays a pioneering role in the fight against hospital-acquired infections. The country is an often-cited role model. But can other countries simply adopt the same system? And what makes it so different? MEDICA asked expert Prof. Alexander W. Friedrich.
03.04.2017Infectious diseases come unnoticed and can have severe consequences. Prevention through good hygiene is the best protection for people in hospitals. This is especially necessary for weakened patients whose immune systems are not able to fight back the infections by themselves. When they still fall ill, physicians need to be quick to diagnose and treat them.
03.04.2017The laboratory is one of the most important and pivotal bastions in patient care. In the laboratory, acute, chronic and genetic diseases are diagnosed, the progression of diseases such as diabetes is regularly checked or specialists look for biomarkers to adapt cancer therapies.