13/05/2021Trained to see patterns by analyzing thousands of chest X-rays, a computer program predicted with up to 80 percent accuracy which COVID-19 patients would develop life-threatening complications within four days, a new study finds.
12/05/2021The research found that injection of the trace mineral manganese could enhanced MRI scans so that they provided more accurate details of heart function than traditional MRI methods.
22/04/2021Screening for a sometimes fatal condition among patients with a rare autoimmune disease could soon – thanks to a computer algorithm – become even more accurate.
21/04/2021A smartphone-based electrocardiogram (ECG) screening accurately detected previously unknown atrial fibrillation in American Indians, and more than half who were diagnosed with the irregular heart rhythm were younger than the recommended screening age of 65, according to new research published today in the Journal of the American Heart Association.
21/04/2021An artificial intelligence-driven system that automatically combs through brain MRIs for abnormalities could speed care to those who need it most, according to a study published in Radiology: Artificial Intelligence.
20/04/2021The idea is as appealing as it is obvious: After a diagnosis of painful hip osteoarthritis, medical imaging creates a high-resolution 3D image of the defunct hip joint – and thus the basis for a customized implant. The data is processed further and ultimately ends up as a digital blueprint in a 3D printer, which produces the individual piece with a precise fit and at optimized cost.
20/04/2021A technology called light-sheet fluorescence imaging shows promise for imaging brain activity in 3D with high speed and contrast (overcoming multiple limitations of other imaging technologies).
19/04/2021The processing of information inside the brain is one of the body's most complex processes. Disruption of this processing often leads to severe neurological disorders. The study of signal transmission inside the brain is therefore key to understanding a myriad of diseases.
14/04/2021It cannot be denied that, over the past few decades, the miniaturization of electronic devices has taken huge strides. Today, after pocket-size smartphones that could put old desktop computers to shame and a plethora of options for wireless connectivity, there is a particular type of device whose development has been steadily advancing: wearable biosensors.
14/04/2021A recent case study from North Carolina State University and the University of North Carolina at Chapel Hill demonstrates that, with training, neural control of a powered prosthetic ankle can restore a wide range of abilities, including standing on very challenging surfaces and squatting.
13/04/2021New insights into the three-dimensional (3D) morphology of the human uterine endometrium could advance our understanding of the mechanisms of endometrial regeneration and fertilized egg implantation while clarifying the pathogenesis of menstrual disorders, infertility and endometrium-related diseases such as adenomyosis, endometriosis, endometrial hyperplasia and endometrial cancer.
13/04/2021In cancer, cells get out of control. They proliferate and push their way into tissues, destroying organs and thereby impairing essential vital functions. This unrestricted growth is usually induced by an accumulation of DNA changes in cancer genes – i.e. mutations in these genes that govern the development of the cell.
02/04/2021A new study finds that patients with Obsessive Compulsive Disorder (OCD) as well as other psychiatric comorbidities, such as autism spectrum or tic disorders, may respond well to Deep Brain Stimulation (DBS).
01/04/2021How do viral pathogens succeed in penetrating human cells? Which cellular mechanisms do they use to multiply efficiently and, in doing so, how do they change the structure of their host cell? These questions are the focus of a pan-European research project called "Compact Cell-Imaging Device" (CoCID), in which Heidelberg scientists are playing a major role.
01/04/2021First of its kind 3D organoid models of nasopharyngeal cancer help to fine-tune radiation doses, and lower the chances of Nasopharyngeal Cancer recurrence and reduce mortality rate.
31/03/2021Although the development of secondary cancerous growths, called metastasis, is the primary cause of death in most cancers, the cellular changes that drive it are poorly understood. In a new study researchers at the University of Illinois Urbana-Champaign have developed a new modeling approach to better understand how tumors become aggressive.
31/03/2021A team led by investigators at Weill Cornell Medicine and NewYork-Presbyterian has used advanced technology and analytics to map, at single-cell resolution, the cellular landscape of diseased lung tissue in severe COVID-19 and other infectious lung diseases.
30/03/2021A team of scientists led by Nanyang Technological University, Singapore (NTU Singapore) has developed a diagnostic test that can detect the virus that causes COVID-19 even after it has gone through mutations.
30/03/2021Monitoring the progression of multiple sclerosis-related gait issues can be challenging in adults over 50 years old, requiring a clinician to differentiate between problems related to MS and other age-related issues. To address this problem, researchers are integrating gait data and machine learning to advance the tools used to monitor and predict disease progression.
29/03/2021International genomics research led by the University of Leicester has used artificial intelligence (AI) to study an aggressive form of cancer, which could improve patient outcomes.
29/03/2021Scientists have designed a portable 3D imaging device which will improve the treatment and diagnosis of cancer. Current handheld gamma imaging tools are small and easy to use, but are limited to providing 2D information, giving doctors and surgeons only part of the overall picture. Much larger systems are able to give three dimensional images, however, they are bulky and complex.
26/03/2021Scientists have produced the first high-resolution 3D image of the sarcomere, the basic contractile unit of skeletal and heart muscle cells, by using electron cryo-tomography (cryo-ET).
26/03/2021Hypnosis relieves pain, reduces mental distress and promotes recovery after surgical interventions - this has been shown in a meta-analysis recently published in Clinical Psychology Review. By evaluating 50 individual studies with over 4000 patients, scientists from Jena and Leipzig examined the efficacy of hypnosis in the context of surgical interventions.
25/03/2021A research team consisting of materials scientists from the Max Planck Institute of Colloids and Interfaces (MPICI) in Potsdam and biologists from Cornell University in Ithaca, USA revealed that bones may grow in response to certain signals from a distant breast tumor. This may be a preemptive defense mechanism against skeletal metastasis.
24/03/2021Mapping neural activity to corresponding behaviors is a major goal for neuroscientists developing brain-machine interfaces (BMIs): devices that read and interpret brain activity and transmit instructions to a computer or machine.
24/03/2021Brazilian researchers tested the capacity of different materials to produce sensors for the detection of PCA3, a gene that is overexpressed in prostate cancer. The technique can also be used to diagnose infectious diseases, including COVID-19.
23/03/2021An international team of scientists from Nanyang Technological University, Singapore (NTU Singapore), Brown University and the Massachusetts Institute of Technology (MIT) has developed an artificial intelligence (AI) platform that could one day be used in a system to assess vascular diseases, which are characterised by the abnormal condition of blood vessels.
23/03/2021Close scrutiny of basic vital functions supports a patient's care and recovery, but hospital resources and existing technological solutions might not be adequate to the task. VTT and its partners are developing wearable sensors, which keep track of the patient's basic vital functions without interruption, sending the information wirelessly to a monitoring system.
12/03/2021Magnetic resonance imaging (MRI) is already widely used in medicine for diagnostic purposes. Hyperpolarized MRI is a more recent development and its research and application potential has yet to be fully explored. Researchers at Johannes Gutenberg University Mainz and the Helmholtz Institute Mainz have now unveiled a new technique for observing metabolic processes in the body.
09/03/2021Robotics has been gaining importance in many areas of life for years, not least in medicine. Robots are already being used in the operating room today, but they do not always play the leading role – a circumstance that will certainly change in the long term.
03/03/2021Researchers at CÚRAM, the SFI Research Centre for Medical Devices based at National University of Ireland Galway, and BIOFORGE Lab, at the University of Valladolid in Spain, have developed an injectable hydrogel that could help repair and prevent further damage to the heart muscle after a heart attack.
03/03/2021A joint research team co-led by City University of Hong Kong (CityU) has developed a new soft tactile sensor with skin-comparable characteristics. A robotic gripper with the sensor mounted at the fingertip could accomplish challenging tasks such as stably grasping fragile objects and threading a needle.
01/03/2021Keeping your distance, washing your hands, wearing a mask – such protective measures have been the order of the day since the SARS-CoV-2 pandemic began. But appropriate products or procedures are not suitable for everyone, are often unavailable or, despite everything, carry a residual risk. The need for new, better solutions is high. But necessity is the mother of invention.
01/03/2021When urgently needed products such as masks become scarce or conventional disinfection processes reach their limits, inventiveness is called for. And there is usually plenty of it in times of crisis. What innovations has the current corona pandemic already produced? How can they supplement or even replace existing products and processes?
24/02/2021According to an open-access article in ARRS' American Journal of Roentgenology (AJR), COVID-19-related disseminated leukoencephalopathy (CRDL) represents an important - albeit uncommon - differential consideration in patients with neurologic manifestations of coronavirus disease (COVID-19).
22/02/2021Researchers from Hanover Medical School (MHH), Mainz University Hospital and HELIOS University Hospital Wuppertal at Witten/Herdecke University are leading an international, multidisciplinary consortium that makes high-resolution, three-dimensional X-ray images of the human body possible.
19/02/2021With the help of artificial intelligence (AI) a German-American team of scientists deciphered some of the more elusive instructions encoded in DNA. Their neural network trained on high-resolution maps of protein-DNA interactions uncovers subtle DNA sequence patterns throughout the genome, thus providing a deeper understanding of how these sequences are organized to regulate genes.
19/02/2021Mass spectrometry (MS) is a powerful method for biomarker analysis because it enables highly sensitive and accurate measurement of target molecules in clinical samples. The application of MS to clinical diagnosis, such as neonatal metabolic screening, has been progressing with a focus on metabolite markers.
18/02/2021Anyone needing a tomography gets the clearest possible images of an organ or other body structure slice by slice. But the further inside the potential problem lies, the more difficult it is to obtain high-resolution images in magnetic resonance imaging. An international team of scientists has developed a high-frequency coil that allows for much better range inside the body, among other advantages.
18/02/2021Is the tissue healthy or pathologically altered? Is the antibiotic effective against a certain bacterium or is the bacterium resistant to it? Raman spectroscopy can help to answer such questions quickly and precisely. However, one challenge for the use of the light-based analysis method in everyday clinical practice is that the results can be highly sensitive to the measurement conditions.
17/02/2021Engineers at the University of California San Diego have developed a soft, stretchy skin patch that can be worn on the neck to continuously track blood pressure and heart rate while measuring the wearer's levels of glucose as well as lactate, alcohol or caffeine. It is the first wearable device that monitors cardiovascular signals and multiple biochemical levels in the human body at the same time.
16/02/2021Researchers from Regenstrief Institute and Indiana University School of Medicine have developed and validated a short questionnaire to help patients report symptoms and assist healthcare providers in assessing the severity of symptoms, and in monitoring and adjusting treatment accordingly.
16/02/2021MIT researchers have invented a new type of amputation surgery that can help amputees to better control their residual muscles and sense where their "phantom limb" is in space. This restored sense of proprioception should translate to better control of prosthetic limbs, as well as a reduction of limb pain, the researchers say.
15/02/2021To study early stages in embryonic development in the cell culture dish, scientists use so-called human pluripotent stem cells (hPSC). These are cells with have remarkable special properties that can be multiplied as they can indefinitely multiply and are capable of forming any functional cell type of the body.
15/02/2021For the first time, engineered heart muscle (EHM) from human induced pluripotent stem cells (iPSCs) will be used to treat patients with heart failure. After regulatory approval, recruitment of the first patient for the first-in-class, first-in-patient BioVAT-HF early clinical trial has started in Göttingen, Germany.
27/01/2021Drug research and artificial skin replacement - these are the areas in which tissue engineering and bioprinting are already used today. What else could be possible in the future? We asked Dr. Nadine Nottrodt from Fraunhofer ILT and Prof. Sabine Neuß-Stein from RWTH Aachen University Hospital!
11/01/2021According to the WHO, around 600 million people worldwide suffer from chronic respiratory diseases such as asthma. Key in the fight against these diseases is therapy adherence, but many sufferers often find this difficult. The result is increased hospitalization, which ultimately comes at the expense of the healthcare system. Smart and mobile technologies could change that.
01/01/2021There are many different kinds of mobile devices to help people with chronic diseases. Asthma is one of those diseases, which can be monitored with wearables to improve everyday life. Especially for parents, the stress and anxiety which come with asthma-afflicted children can be reduced with a reliable solution like Respia.
01/12/2020Implants, prostheses and various other components made of plastic, metal or ceramics are already being produced by additive manufacturing. But skin, blood vessels or entire organs from the printer – is that possible? For years now, intensive research has been underway into the production of biologically functional tissue using printing processes. Some things are already possible with bioprinting.
01/12/2020It aims at the production of test systems for drug research and gives patients on the waiting lists for donor organs hope: bioprinting. Thereby biologically functional tissues are printed. But how does that actually work? What are the different bioprinting methods? And can entire organs be printed with it? These and other questions are examined in our Topic of the Month.
01/12/2020The big hope of bioprinting is to someday be able to print whole human organs. So far, the process has been limited to testing platforms such as organs-on-a-chip. That's because the actual printing process already poses challenges. Scientists need suitable printing materials that ensure the cell's survival as it undergoes the procedure. The Fraunhofer IGB is researching and analyzing this aspect.
01/12/2020How do cells react to certain drugs? And how exactly is new tissue created? This can be analyzed by using bioprinting to embed cells in fine frameworks. However, current methods are often imprecise or too slow to process cells before they are damaged. At the TU Vienna, a high-resolution bioprinting process has now been developed using a new bio-ink.
22/09/2020Patients who receive a prosthesis after the amputation of a limb often have to train for weeks or months until they can control the technology and use it in everyday life without problems. At the Medical University of Vienna, the world's first bionic prosthesis has now been developed that has a closed control loop and enables immediate, intuitive use.
10/08/2020This is how a conventional ultrasound scan works: patients lie down on a table next to the ultrasound machine. A doctor uses a probe to scan the part of the body in question, while he or she looks at the pictures on a monitor. In other words, the physician either focuses on his/her hand on the patient or the monitor. The Fraunhofer IGD wants to change this process as part of the "sonAR" project.
03/08/2020Patient monitoring systems in the ICU sound up to 700 alarms on average per patient per day, which boils down to one alarm every two minutes. An excessive number of them are false alarms. This generates vast amounts of data, which can make it difficult for doctors and nurses to identify the most critical alarms to manage. It also has a negative effect on the treatment of intensive care patients.
08/06/2020Professional athletes depend on a speedy recovery from sports injuries or surgery because their livelihood depends on their physical fitness. Returning to competition too soon after injury can have negative health consequences. Standard tests are now combined with virtual reality to determine the optimal time to return to play.
02/06/2020After a stroke, a patient’s life depends on getting acute care at a hospital. Vital monitoring systems ensure safe and effective treatment. An innovative tomographic imaging system is designed to help prevent the patient’s risky journey to radiology and to enable bedside monitoring of cerebral blood flow.
02/06/2020If someone is having a stroke, you call an ambulance. But getting to the hospital can be time-consuming. To prevent long-term disabilities and death, patients need to be treated as quickly as possible. According to a recent study by the Charité – Universitätsmedizin Berlin, mobile stroke units play a key role in this setting.
23/03/2020Germs such as bacteria, viruses or pathogenic fungi can spread from one person to another through direct contact when we shake hands or touch objects. People touch door handles and push elevator buttons in public places and constantly move in and out of spaces. Regular manual high-level disinfection is practically impossible. UVentions GmbH has found an intelligent solution for this problem.
22/01/2020Patients have to undergo a gastroscopy to rule out gastrointestinal conditions. Many dread this procedure since a thin, flexible tube is being pushed through the esophagus and stomach. Ovesco Endoscopy AG has teamed up with other project partners in the nuEndo research project to develop a capsule endoscopy device that is tiny, easy to swallow and makes the test more comfortable for the patient.
01/01/2020Joints can suddenly or gradually deteriorate and lose their natural strength, whether it’s due to accidents, diseases or simple wear and tear. In some of these cases, implants of artificial joints – endoprostheses - can help. As a joint replacement, they are designed to stay in the body for as long as needed and as such improve the patient’s quality of life and mobility.
01/01/2020Today, people tend to live longer, while an increasing number of patients suffer from osteoarthritis. Even younger generations are now at a higher risk of getting osteoarthritis due to the frequent use of mobile devices. The EU research project APRICOT aims to develop a novel type of implant for the treatment of osteoarthritis of the hands – helping patients heal themselves.
01/01/2020Surgery is required if you need an artificial joint. Patients and doctors must select the type of surgery that’s best suited and choose between robot-assisted, traditional or minimally invasive surgical approaches. Post-operative risks should be kept to a minimum, while benefits should outweigh any possible complications.
01/01/2020When natural joints lose their ability to function, they can be completely or partially replaced by artificial joints, also called endoprostheses. Endoprostheses must be of a certain quality, as they should remain in the body as long as possible. In addition to some risks, endoprostheses can also contribute to a mobile and carefree life for young and old.
12/12/2019Diagnostic testing usually takes some time and a sterile environment to get the results. To cut down on the costs and effort spend on these tasks there are different diagnostic tests. One of them are single-use tests offered by SensDx S.A. The technology behind them not only makes the process faster and easier, but provides the opportunity to expand into home use in the future as well.
02/12/2019Smart home systems are a perfect example of how technology can make our daily lives easier. The fact that they can use a tablet to adjust lighting and blinds in every room benefits older adults in more ways than one. These types of technical systems are a part of Ambient Assisted Living (AAL) and create a safe living environment for older persons.
02/12/2019Too many people in need of care and not enough health care professionals – we all know the problem. For years, research is underway to find digital solutions for AAL to support the growing number of older & sick adults. These new technologies aim to both alleviate caregiver burden and enhance everyday life of people in need of care with a minimum level of constraint whilst promoting independence.
02/12/2019Average life expectancy keeps increasing, while birth rates are declining – at least when it comes to most industrial nations. The coming decades will see a decreasing number of gainfully employed people versus more and more senior citizens and people in need of care. It's a trend that already pushes healthcare to the brink. That's why we desperately need new concepts. One of them is AAL.
02/12/2019Our ageing society is confronted with fewer and fewer workers. One of the many consequences is a shortage of skilled nursing staff. Ambient Assisted Living should solve this problem. By equipping the living environment of elderly people or people in need of care with (technical) assistance systems, they are to be given more self-determination and security. The nursing staff also benefits.
08/11/2019If physicians suspect an acute myocardial infarction, they first order an ECG. This test is very established and allows cardiologists to quickly diagnose acute heart attacks – though the test does not detect less common heart attack symptoms. So far, those patients had to wait up to twelve hours before a heart attack could be accurately diagnosed or ruled out. But things are about the change.
04/11/2019Soon, the world's largest trade fair for medical technology will open its doors again: More than 5.000 exhibitors will present their newest products and ideas at MEDICA from 18 to 21 November. You will not only meet well-known companies here, but also lots of young start-ups. Or, you can visit the MEDICA forums and conferences to experience a rich program of lectures and discussions.
08/10/2019The healthcare market offers a multitude of microscopes that make cells visible to the human eye. The same applies to AI-based software for image analysis. After taking the microscopic images, scientist are faced with large volumes of scans with usually low resolution. Yet when all aspects merge together, they open up a the world of digital pathology.
01/10/2019The medical market is booming - medical ideas and visions for the future are more in demand than ever. Especially at MEDICA START-UP PARK 2019 young founders want to present their product innovations. Develop business contacts, meet investors and experience an international environment in just one place. Discover in our Topic of the Month what makes MEDICA START-UP PARK unique.
01/10/2019When the halls of MEDICA are open to the world to showcase medical innovations, one joint exhibition booth is guaranteed to attract special attention - the MEDICA START-UP PARK. The startups that present their advances in this setting are interesting to visitors and investors, yet long-time exhibitors and big businesses can also benefit from building relationships with these young companies.
01/10/2019Pneumonia, COPD or cystic fibrosis – people with such lung diseases have to consult their doctor regularly. Little children have to undergo certain measurements by the doctor, too. In order to save people`s need to visit a doctor, telemedicine offers many ways to do examinations at home.
23/09/2019For patients waiting for donor organs, every day can mean the difference between life and death. Making things even more complicated is the fact that not every organ is a compatible match with the patient. It would mean enormous progress if we could grow organs from the patient's own cells in the lab. That's why patients with heart disease place big hope in tissue engineering.
02/09/2019More patients, more examinations, more CT images – in radiology there is too much work for too few physicians. CT scans are evaluated in the shortest possible time, which leads to anomalies being overlooked. Artificial intelligence, on the other hand, works with constant speed and performance, which is why radiological routine increasingly relies on its support.
02/09/2019Radiology is a field that produces large volumes of data, which can no longer be managed without the help of intelligent systems. This is especially true when it comes to the interpretation of medical images. While this takes physicians years of training and experience, several hours of work and the highest level of concentration, AI only requires a few seconds to accomplish the same task.
02/09/2019In modern medicine, especially in the field of imaging, huge amounts of data are produced – so much that radiologists can hardly keep up with diagnosing the images. Artificial Intelligence could be the solution to this problem. But how exactly can it help in this task? How can man and machine work together? And what else will be possible in the future with the support of intelligent systems?
22/08/2019The German Medical Award will take place on November 18, 2019, as part of the MEDICA trade fair in Düsseldorf. The ceremony emphasizes the commitment to excellence in cutting-edge care for patients. Doctors, clinical centers and companies in the medical and healthcare industry can demonstrate their achievements in medicine and management in hopes of receiving the coveted award.
08/08/2019After their tumor has been removed, some patients have to return to the hospital to undergo surgery again. That's because the tumor was not precisely identified and was subsequently not completely removed. That's both an ethical and financial dilemma. A new surgery-adjacent procedure is designed to rapidly and accurately detect tumors.
01/08/2019An untreatable infection is a nightmare for physicians and potentially life-threatening to the patient. Unfortunately, more and more pathogens emerge that are resistant to drugs, especially antibiotics. We need to use our drugs smartly and come up with technical solutions as well to prevent our weapons from blunting in the future.
08/07/2019On November 18th, 2019, parallel to the first day of MEDICA, the world forum for medicine, the Diagnostics Partnering Conference (DxPx Conference) will take place in Düsseldorf, bringing together stakeholders in the diagnostics and research tool industry. The DxPx Conference focuses on discovering technologies, finding financing and investment opportunities and forming collaborative partnerships.
01/07/2019Physical activity plays a big role in today's society. Whether you are an amateur or professional athlete – incorporating exercise into your life positively impacts your mental and physical health. Ideally, sport should be fun, pressure-free and not overburden you. But can you measure individual performance and align it with sports?
01/07/2019Those who integrate physical activities into their own lifestyle live healthier and more balanced. But where are the physical limits? Can health status measurements also be carried out on the road? Discover more about how sports medical examinations contribute to maintain performance and minimize health risks in our Topic of the Month.
01/07/2019Stationary or mobile - competitive athletes rely on regular health assessments. They must deliver peak performance and be physically fit during competitions. But when do they reach their physical limits? Are there any devices that provide information, no matter where the test subject is located?
24/06/2019Improving technology transfer from research to industry and driving robotics development - that's the idea behind the KUKA Innovation Award. This year’s topic is "Healthy Living". Applicants from around the world were tasked with creating a robot application for healthcare settings. Now, the finalists, who will showcase their innovations at the MEDICA 2019 trade fair have been selected.
03/06/2019For most people, enjoying a good quality of life means having the ability to move freely, safely and independently. Intensive and costly rehabilitation is needed if this is no longer an option after a stroke for example. We are introducing some projects that deliver innovative robotic solutions.
03/06/2019Humans are living longer than ever but still want to continue to live independently as they age. Meanwhile, our motor and cognitive abilities decline as we age, sometimes as the effects of a stroke. The number of people in need of long-term care is growing at breakneck speed. At the same time, fewer and fewer young people choose stressful careers as caregivers.
03/06/2019They work with power, precision and tirelessly. This makes robots an ideal instrument for rehabilitation. In gait or motor training, movement sequences must be repeated thousands of times so that they can be learnt anew. What tires the patient and costs the therapist's time can easily be managed by robot-assisted systems. Learn more about the possibilities of robotics in rehabilitation.
08/05/2019Atrial fibrillation is the most common type of persistent cardiac arrhythmia (irregular heart rhythm). Researchers estimate that 1.8 million Germans are presently affected by this disease. The condition is difficult to diagnose, frequently goes undetected and may result in a stroke. A new smartwatch medical app is designed to help patients detect atrial fibrillation before it’s too late.
01/04/2019All information from our body and the environment converges in our brain and is transformed into reactions in milliseconds. It is essential for medicine and research to know what our switching centre looks like. Functional methods are used to observe it more closely during work.
01/04/2019Our brain is the command center of our body. This is where all information and impressions are collected and converted into responses and movements. Modern imaging techniques offer physicians and researchers unique insights into the actions of the human central nervous system. The functional imaging technique allows them to watch our brain in action.
01/03/2019COPD is considered the third most common cause of death worldwide and mainly affects smokers. It is not curable, but with the right combination of early diagnosis, therapy and self-management, a significant part of the quality of life can be regained. The comprehensive care is supported by various devices and technical tools. Learn more about the all-round care of COPD in our Topic of the Month.
22/02/2019According to the WHO, ten percent of babies worldwide are born prematurely. Since most organs of these tiny babies have not fully developed yet, it can quickly lead to complications and disorders and most notably affect the lungs of the premature infants. What's more, infections require gentle treatment, as the preemies themselves are fragile and susceptible – making this a challenging situation.
01/02/2019In vitro processes and animal tests are used to develop new medications and novel therapeutic approaches. However, animal testing raises important ethical concerns. Organ-on-a-chip models promise to be a feasible alternative. In a system the size of a smartphone, organs are connected using artificial circulation.
01/02/2019The liver, nervous tissue or the intestines: all are important human organs that have in the past been tested for their function and compatibility using animal or in vitro test methods. In recent years, TissUse GmbH, a spin-off of the Technical University of Berlin (TU Berlin), has launched multi-organ chip platforms. But that’s not all.
01/02/2019Organ-on-a-chip systems are technically a great enhancement of medical research because they facilitate testing of active ingredients on cell cultures in the chambers of a plastic chip. This replaces animal testing and improves patient safety. That being said, they are not a true-to-life replication of the human body and can only simulate a few functions and activities.
01/02/2019So far in vitro methods and animal experiments have been used to determine the causes of diseases, research therapeutic approaches and predict the effect of drugs. Organ-on-a-chip models now offer a more accurate and ethically justifiable alternative. Find out more about the models, their advantages and future developments in our Topic of the Month.
22/01/2019Whether in the office, at school or behind the wheel: we spend a lot of time sitting and often stay in the same position for too long. The possible side effects are stiffness, back problems and pain. The SensA-Chair smart seating solution combats decreased mobility and ensures dynamic sitting.
08/01/2019Parkinson's disease is a progressive nervous system disorder that primarily affects movement of patients and makes their everyday lives very challenging. It also makes regular doctor appointments and treatment sessions necessary. "TelePark" - a project that collects different movement-related parameters using sensors and apps is designed to improve the quality of life for Parkinson’s patients.
02/01/2019There are 425 million people with diabetes in the world. Heart problems, kidney failure or blindness - these can all be consequences of the metabolic disease. Diabetes patients now have the possibility of being treated digitally.
02/01/2019Diabetes mellitus or simply diabetes has become very common and is often described as a lifestyle disease. More and more people are suffering from this chronic metabolic disorder. Next to established diagnostic procedures, digital retinal screening has shown to be successful - a promising technique that will also play an important role in the diagnosis of other diseases in the future.
19/12/2018Continuous monitoring is an essential process with every disease. In the case of eye disorders, frequent retina measurements can facilitate early detection of deterioration to quickly initiate intervention. This calls for comprehensive care settings, easy ways to take measurements and prompt results. However, in reality, this is rarely the case.
10/12/2018So far, lower arm prostheses often only functioned as a cosmetic disguise to conceal the missing body part. While newer models help the wearer with grip patterns, every hand grip has to be readjusted and newly activated. There is still no prosthetic device that is easy to control and allows a flexible response to objects the wearer is grasping.
03/12/2018Strengthening and healing thanks to the power of electrical pulses - is that really possible? When mobility is restricted or muscles are no longer as strong as they used to be, electrical treatment options can lead to improvement or even cure of diseases. But why are more and more people turning to these alternatives, what are the advantages and what are their limitations and drawbacks?
03/12/2018The treatment for many neurological and mental disorders is far from being an easy feat. Drug therapies always require accurate medication adjustments, while brain surgeries have the potential for risks and complications. Non-invasive brain stimulation takes a different approach: magnetic fields and electric current change the activities in the brain - without putting the patient at risk.
03/12/2018Conventional medicine is taught at universities and is generally acknowledged. But other therapies have also proven their worth, such as electrical healing methods, which contribute to recovery and a better quality of life. In our Topic of the Month you learn about in which cases they are used, what their benefits are and what the current status of these methods is on the medical market.
22/11/2018Every year between 250.000 and 500.000 people suffer a spinal cord injury, MoreGrasp is intended to make their lives easier. The project aims to restore the lost gripping function in people with high paraplegia. Researchers at Graz University of Technology have developed a neuroprosthesis that is currently undergoing a feasibility study.
08/11/2018Not enough exercise, an unhealthy diet: Kidney stones develop when urine contains too many insoluble compounds and are now one of the most common diseases worldwide. The ailment annually affects 1.2 million people in Germany alone. The stones are broken up and taken out via endoscopic surgery. Now it’s possible to remove even the tiniest residual fragments. The solution: a biocompatible adhesive.
02/11/2018This is what diagnostic investigation normally looks like: a patient sample is collected, sent to the laboratory and analyzed. Once that's completed, the patient is told of the lab test result. But if the patient is a high-performance athlete and has to follow and stick to a rigid training schedule, he or she needs these results immediately. What makes this possible? Point-of-care testing!
22/10/2018Today’s society is faced with an aging population. The past has seen the development of many methods for measuring body composition in older adults. However, some of these techniques are not available to medical practices and hospital facilities or are in dire need of optimization.
22/08/2018Mix-ups, contamination and sample loss – most errors in pathology happen when specimen are received. Countless samples arrive daily at the laboratory, while the sample entry process is very monotonous. As a result, the work is inefficient. The start-up company inveox has now developed a system that automates the processes in the pathology laboratory, thus making them more efficient.
08/08/2018Some solutions are simple, though not necessarily obvious. The WAKE-UP study, which included 70 participating European stroke centers, has now studied a relatively simple procedure to manage the acute care of stroke patients and avoid potential long-term effects. Best of all, it is available wherever MRI is offered.
23/07/2018Every year, more than 250,000 patients worldwide receive heart valve implants. Children require repeated replacement surgery because their bodies are still growing, the prosthetic heart valves are not. Regenerative heart valves solve this problem. Until now, we have only been able to monitor how these living implants develop in the body after the fact. Computer models now make this predictable.
09/07/2018People who are not ill and do not show any symptoms typically do not visit the doctor. And while most people know that preventive medical checkups for cancer, for example, are important, they still avoid them. They tend to be very hesitant because the doctor might detect a serious illness. In the future, a new type of implant could make it easier to go to a screening test.
22/06/2018A drop of blood provides a lot of valuable information. However, it takes several hours to analyze the blood of a patient and make a diagnosis. This takes away a lot of time that's crucial for treatment. A new method intends to considerably speed up this process by testing the cells in the blood in terms of their deformability and immune response.
22/05/2018This unusual ally can be extremely valuable in the fight against inflammation in the body: CO (carbon monoxide). As a therapeutic gas, it also promises relief for inflammatory gastrointestinal diseases. Having said that, it is difficult to transport the active ingredient to the exact desired location.
17/05/2018Ventricular fibrillation is a life-threatening condition that occurs when the heart muscle exhibits a rapid, erratic beat. The cause might be a circulatory system disease or heart attack. Researchers in Göttingen are now developing an ultrasound technique to get to the bottom of ventricular fibrillation and cardiac arrhythmias and facilitate better treatment options.
08/05/2018Multidrug-resistant organisms that are treated with a dosage that exceeds the regular dose a hundred times and at temperatures of over 40 degrees Celsius – the human organism is unable to handle it. Yet if the diseased organ is treated outside of the body, extreme conditions are an option. For the first time, physicians have succeeded in treating a severe case of pneumonia by using the OCS.
02/05/2018When human movements are no longer as smooth as they should be – due to misalignments or as the result of an injury for example – biomechanical measuring systems spring into action. Thanks to different types of sensors and optical technologies, physicians, therapists, and sports scientists embark on a search for possible causes and corrective options.
23/04/2018A bypass is a complicated structure. It is either made of synthetic materials that can cause blood clots and infections or created by using the patient’s veins. However, the latter often does not yield adequate material. A newly developed bioreactor could solve this problem in the future. It is designed to tissue engineer vascular grafts by using the body’s own material.
09/04/2018When a skin lesion is suspected to exhibit malignant changes, it is usually promptly removed. However, not all cases require an excision of the affected tissue. The startup company Magnosco has developed a procedure that uses a laser to support the diagnosis and early detection of malignant melanoma.
22/03/2018Virtual reality and medicine are increasingly mentioned in the same context. In addition to the development of applications that support the treatment of patients suffering from chronic pain and anxiety, this technology also benefits medical staff. Two months ago, the Ulm University Hospital has opened the VR Lab, where medical students can train and learn with the help of 3D organs.
08/03/2018Automation makes work life easier in many ways but is it also a solution for analyzing medical images? Is a computer actually reliable enough to assist in the medical decision making process? Researchers in Landshut examine how machine learning algorithms can work more reliably and support radiologists.
01/03/2018Conventional cancer treatment selection typically depends on the location of the tumor. However, this approach ignores the distinct gene mutations in the tumor of the individual patient. New cancer research approaches increasingly emphasize the concept of personalized therapy.
01/03/2018Personalized medicine does not follow a "one-size-fits-all" treatment approach but emphasizes a "tailor-made" paradigm, meaning a treatment is customized to each individual person's case. For patients, this increases the chances of treatment success and means fewer side effects. While the approach originates in the field of oncology, it is now also increasingly applied to other disease patterns.
01/03/2018Everyone is different. This statement also applies to our health. Cancer, in particular, can look and progress differently depending on the individual person. That’s why every patient ideally also needs a customized treatment that is tailored to their individual needs. But how feasible is this idea?
22/02/2018Here on Earth, all experiments are bound by gravitation. Yet, freed from gravity's grip, tumor cells, for example, behave in an entirely different way. As part of the "Thyroid Cancer Cells in Space" project by the University of Magdeburg, smartphone-sized containers carrying poorly differentiated thyroid cancer cells are sent into space.
08/02/2018When body tissue is reconnected during a tumor operation in the gastrointestinal tract, surgeons need information about the current state of these so-called anastomoses. The new, non-invasive hyperspectral imaging technology now makes it possible to measure the crucial parameters during surgery and thereby increase surgical precision.
22/01/2018Research does not always occur in laboratory settings. As part of citizen science, citizens collect data and make it available for research projects. Now, this approach is also adopted in medicine by way of patient science: in a new project, patients take part in cystic fibrosis research. The goal is to improve the lives of those who are affected by this chronic disease.
08/01/2018Few patients with heart failure are fortunate enough to receive a donor's heart. Ventricular assist devices (or heart pumps) have been around for several years and are designed to buy time as patients wait for a transplant. Unfortunately, the body doesn't always tolerate these devices.
04/01/2018While it is commonplace for operating room staff to work together as a team, the collaboration of operating room systems does not always work so well – many devices are still separated from one another, causing the OR processes to be prone to mistakes. The same applies to surgical navigation technologies that represent the interface between imaging, the surgeon and therapeutic devices.