Regenerative medicine: helps the body healing -- MEDICA - World Forum for Medicine

Image: immune cells counting each other; Copyright: Northwestern University

Immunology: cells consult each other to make decisions

14.02.2020

Scientists and physicians have long known that immune cells migrate to the site of an infection, which individuals experience as inflammation - swelling, redness and pain. Now, Northwestern University and University of Washington researchers have uncovered new evidence that this gathering is not just a consequence of immune activation.
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Image: mini-gut organoid generated in the lab; Copyright: UC San Diego Health Sciences

Gut-in-a-dish model to define gut leaks

11.02.2020

Leaky gut is most often experienced by older people, patients with cancers or other chronic ailments, and people with especially stressful lifestyles. Stressors break down the zipper-like junctions between the cells that form the gut lining. Microbes and molecules that subsequently leak out through these cell gaps can trigger an immune response, contributing to a variety of diseases.
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Image: Two knees of a woman next to each other, the left knee has a surgical suture; Copyright: panthermedia.net/wujekspeed

Regenerative medicine: creating a new body?

03.02.2020

Regenerative medicine aims to repair the human body after injuries, accidents or major cancer surgery. Unfortunately, we are still not at a stage where this process can achieve optimal results for every conceivable situation. Having said that, various new methods are on the cusp of breakthrough.
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Image: The shoulder of a man with a surgical suture; Copyright: panthermedia.net/JPCPROD

Regenerative medicine: helps the body healing

03.02.2020

Severe wounds heal slowly and leave scars. This is why we have been using regenerative therapies for some time now to accelerate and improve healing. They also help to avoid permanent damage. Still, complex applications like replacing organs or limbs will rather remain vision than become reality for a long time.
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Image: Colored image of a tissue sample; Copyright: UC San Diego Health Sciences

Regenerative medicine: new injection technique for spinal cord repair

03.02.2020

In rodent studies, a new method reduced likelihood of further spinal cord trauma while delivering large doses of potentially reparative stem cells. This approach may have utility for multiple neurodegenerative conditions.
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Image: Cells on a programmable composite of silica nanoparticles and carbon nanotubes; Copyright: Niemeyer-Lab, KIT

Programmable materials for stem cells

21.01.2020

Using DNA, smallest silica particles, and carbon nanotubes, researchers of Karlsruhe Institute of Technology (KIT) developed novel programmable materials. These nanocomposites can be tailored to various applications and programmed to degrade quickly and gently.
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Image: structure of the system; Copyright: Sternberg and Fernández Labs at Columbia University Irving Medical Center

DNA: first images of an 'upgraded' CRISPR tool

20.12.2019

Columbia scientists have captured the first images of a new gene editing tool that could improve upon existing CRISPR-based tools. The team developed the tool, called INTEGRATE, after discovering a unique "jumping gene" in Vibrio cholerae bacteria that could insert large genetic payloads in the genome without introducing DNA breaks.
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Image: Graphic rendering of several cells in a petri dish; Copyright: panthermedia.net/dani3315

Organ-on-a-chip systems: limited validity?

01.02.2019

Organ-on-a-chip systems are technically a great enhancement of medical research because they facilitate testing of active ingredients on cell cultures in the chambers of a plastic chip. This replaces animal testing and improves patient safety. That being said, they are not a true-to-life replication of the human body and can only simulate a few functions and activities.
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