Cardiovascular system: Possibilities of intraoperative imaging -- MEDICA - World Forum for Medicine

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twenty20photos

New material paves the way for remote-controlled medication and electronic pills

23/06/2022

Biomedicines are produced by living cells and are used to treat cancer and autoimmune diseases among other things. One challenge is that the medicines are very expensive to produce, something that limits global access. Now researchers from Chalmers have invented a material that uses electrical signals to capture and release biomolecules.
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Image: A smiling man is sitting behind a laboratory device; Copyright: Universität Bielefeld/M.-D. Müller

Universität Bielefeld/M.-D. Müller

Making drug interactions in the liver visible

15/06/2022

Bielefeld University is coordinating a new EU-research project that seeks to produce microscopic liver tissue cultures that can survive for 14 days, while also using imaging methods to investigate how liver cells react to combinations of different medications.
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Image: A hand is holding an object tray with the word “coronavirus” on it in front of a microscope and a screen; Copyright: mstandret

mstandret

Identifying viruses more quickly

14/06/2022

The research project NanoXCAN involving Leibniz Universität Hannover aims to revolutionize virus imaging technology. The European Commission is funding the project with around 4 million euros. Every hospital could benefit, as a rapid and reliable identification of viral subtypes can save lives.
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Image: Drawing of a liver that is connected to a magnifying glass by colorful circles; Copyright: Lili Niu © Novo Nordisk Foundation, Center for Protein Research

Lili Niu © Novo Nordisk Foundation, Center for Protein Research

Early diagnosis of liver diseases by proteomics

06/06/2022

Two or three drinks every day could put your liver in danger. Using proteomics and machine learning, researchers now present a revolutionary tool to predict whether an individual has alcohol-related liver disease and if an individual patient is at risk of disease progression.
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Image: Drawn schematic of a work flow in a laboratory; Copyright: Juliet Percival/MPI für Biochemie

Juliet Percival/MPI für Biochemie

New method revolutionizes cancer diagnosis

24/05/2022

A German-Danish team led by Prof. Matthias Mann has developed a ground-breaking technology called 'Deep Visual Proteomics'. This method provides researchers and clinicians with a protein read-out to understand cancer at single cell-type resolution. The technology was published in the journal Nature Biotechnology and demonstrates its potential in a first application to cancer cells.
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Image: A three-dimensional view of cell activities of skin cancer squamous cell carcinoma.; Copyright: M. Schober/E. Fuchs, Rockefeller University

M. Schober/E. Fuchs, Rockefeller University

New method melds data to make a 3-D map of cells’ activities

20/05/2022

HZI researchers develop molecular probes to detect pathogens in clinical samples.
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Image: Electron micrograph of Staphylococcus aureus; Copyright: HZI/Manfred Rohde

HZI/Manfred Rohde

A bright spot for microbiological diagnostics

19/05/2022

HZI researchers develop molecular probes to detect pathogens in clinical samples.
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Image: A woman is pushed into an MRI; Copyright: Wavebreakmedia

Wavebreakmedia

Hyperpolarized nuclear MR: more precise diagnoses and personalized therapies

17/05/2022

Hyperpolarized nuclear magnetic resonance enables major medical advances in molecular diagnostics, for example for cardiovascular diseases or cancer therapy. Within the framework of the EU collaborative project "MetaboliQs", seven partners developed a microscopy method which enables the analysis of metabolic processes at the single cell level by means of diamond-based hyperpolarization.
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Fraunhofer ILT, Aachen

Process chains for isolation and analysis: from single cells to organoids

17/05/2022

Researchers at the Fraunhofer Institute for Laser Technology ILT are working on new tools for the preparation and analysis of single cells and cell assemblies. The team developed the "Liftoscope", a system for cell sorting for subsequent cultivation that can analyze and transfer biomaterials precisely and in a way that is gentle on cells.
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Image: A man wearing VR glasses stands in front of a screen and looks at a protein structure; Copyright: The University of Texas at San Antonio

The University of Texas at San Antonio

Virtual reality to give UTSA students unique look at proteins

16/05/2022

Francis Yoshimoto, assistant professor in the UTSA College of Sciences’ Department of Chemistry, is introducing his Biochemistry II laboratory students to a new way of learning—using virtual reality headsets to observe and analyze protein structures.
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HiperScan

Fagron acquires majority share of Fraunhofer IPMS' spin-off HiperScan

10/05/2022

Fagron, a leading global company active in pharmaceutical compounding, announced on April 14th the acquisition of HiperScan, the German market leader for reliable raw material identification in pharmacies. HiperScan is a spin-off of Fraunhofer IPMS and the German market leader for reliable and secure identification of starting materials in pharmacies.
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The Biodesign Institute at Arizona State University

A sharper image for proteins

05/05/2022

To fully understand proteins and their myriad functions, researchers have developed sophisticated means to see and study them using advanced microscopy, enhanced light detection, imaging software and the integration of advanced hardware systems. A new study from Arizona State University describes a new technique that promises to revolutionize the imaging of proteins and other vital biomolecules.
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Image: Colored 3D-model of parts of a cell; Copyright: University of Freiburg

University of Freiburg

Insights into the dynamic ultrastructure of the heart

12/04/2022

What happens below the cellular level when the heart contracts and relaxes has long been unexplored. Thanks to new ultra-high-resolution electron microscopy techniques, scientists can now watch the heart beating – almost at a molecular level.
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What intensive care patients really need – Communication via eye-tracking systems

07/04/2022

Patients at the intensive care unit are not always able to communicate with their environment, even if they are conscious. The BG University Hospital Bergmannsheil in Bochum, Germany, now aims to enable them to communicate using an eye-tracking system. Learn in our video interview how this system works, how it was established and what obstacles still need to be overcome.
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Image: A bluely colored tissue sample with bright green dots; Copyright: Team Wolfgang Kastenmüller/Universität Würzburg

Team Wolfgang Kastenmüller/Universität Würzburg

Immune system 'sentinel' cells key to immunotherapy

05/04/2022

The presence of dendritic cells, so-called 'sentinel' immune cells, is vital to maintain and regulate the balance of the body's immune response. Researchers have discovered an essential role of these cells in the treatment of cancer and severe viral infections.
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Image: MediSCAPE imaging of the living human tongue. Copyright: Kripa Patel-Hillman Lab/Columbia Engineering

Kripa Patel-Hillman Lab/Columbia Engineering

New technology could make biopsies a thing of the past

04/04/2022

MediSCAPE, a high-speed 3D microscope designed by Columbia Engineers, can see real-time cellular detail in living tissues to guide surgery, speed up tissue analyses, and improve treatments
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Image: Schematic of optoacoustic neural stimulation; Copyright: Shi, Jiang, et al.

Shi, Jiang, et al.

Optoacoustics for high-precision neuromodulation

01/04/2022

Optoacoustic neuromodulation offers the high penetration depth of ultrasound, plus the high spatial precision of photons, enabling new horizons for neuroscience
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Image: Illustration of the way an optical Cochlear implant functions; Copyright: UMG

UMG

Cochlear implants: Using light to improve hearing

01/12/2021

Cochlear implants are devices that partially restore hearing in wearers. Unfortunately, the signal transmission from the implant to the auditory nerve is still rather basic, thus limiting the sound quality. Future implants could be more accurate in this setting by using light versus electrical pulses to stimulate nerve cells in the ear.
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Image: X-ray image of a blood vessel with a catheter and a balloon; Copyright: PantherMedia/pitchayanank.hotmail.com

A look into the cardiovascular system: Possibilities of medical imaging

02/08/2021

A high degree of precision is required for operations involving the cardiovascular system. This is based on medical imaging. In practice, however, these still face a number of challenges that can impair image quality. The further development of imaging techniques represents a forward-looking field of research in order to be able to improve surgical treatment.
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Image: Blood vessels and nerve tracts of a mouse; Copyright: Helmholtz Zentrum München

SWIR Imaging: The Power of Multi-Color Real-Time Technology

02/08/2021

Image-guided surgery is based on medical imaging. However, past imaging technologies performed while the patient is awake cannot deliver a complete view that facilitates a visual differentiation of structures such as blood vessels and nerve tracts. In a study, scientists developed a non-invasive imaging modality that enables multiplexing, deep tissue penetration, and real-time resolution.
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Image: A young boy is sitting in front of a computer, looking at a 3D scan of his head; Copyright: Artec 3D

Orthopedic technology: 3D scanners change the industry

01/07/2021

Orthopedic technology involves taking a measurement of a specific body part and then creating a medical device, be it prosthesis or orthosis, that fits. While optical scanners are already used for some of these measurements, others are still performed through manual labor and craft to create molds of the body. 3D scanners are changing this.
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Image: A woman sitting in front of a device for an eye examination; Copyright: PantherMedia/Med_Photo_Studio

PantherMedia/Med_Photo_Studio

Alzheimer's disease: early detection using an eye exam

22/03/2021

Alzheimer's disease is still incurable, but if detected early enough, countermeasures can improve treatment and slow the progression. Unfortunately, there is still no reliable early detection test at this juncture. This might soon change thanks to a non-invasive spectroscopy of the retina.
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Image: A group of researchers is discussing a chemical structural formula in front of a whiteboard; Copyright: PantherMedia/depositedhar

Intelligent implants: when the material is the key to the solution

01/02/2021

Today we use implants to stabilize or compensate for injuries inside the body and to aid in the healing process. Implants cannot act autonomously and treat the patient if they deem it necessary. However, it is just a matter of time before this happens because research on intelligent implant materials that respond to stimuli is on the cusp of a breakthrough.
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Image: Surgeon with glasses and 3D-RoboticScope in use; Copyright: bhs-technologies

bhs-technologies

3D-RoboticScope: surgery with a head movement

08/10/2020

Surgery can be very strenuous for a surgeon, as he often has to bend over the patient in a rigid position for hours. For the first time worldwide, a surgical microscope that can be controlled by head movements was used at the University Hospital Zurich. This makes surgery not only more comfortable, but also faster.
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Image: A young laboratory technician with AR glasses uses a pipette, he is surrounded by different bubbles with text; Copyright: Helbling Technik Wil AG

Augmented Reality for better laboratory results

01/09/2020

Accuracy is paramount in laboratory settings and ensures that lab results are valid. Errors in a lab can render series of tests unusable and waste precious time and money. In the medical realm, this might even result in clinical trial errors. Augmented reality (AR) can help laboratory technicians to prevent errors and guide their work in the future.
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Image: Application of AR sonography; Copyright: Fraunhofer IGD

Fraunhofer IGD

Augmented reality ultrasound: putting the focus on patients

10/08/2020

This is how a conventional ultrasound scan works: patients lie down on a table next to the ultrasound machine. A doctor uses a probe to scan the part of the body in question, while he or she looks at the pictures on a monitor. In other words, the physician either focuses on his/her hand on the patient or the monitor. The Fraunhofer IGD wants to change this process as part of the "sonAR" project.
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Image: Intensive care unit with VitalSky installation over two beds; Copyright: Markus van Offern

VitalSky: how an artificial sky improves ICU patient recovery

03/08/2020

Delirium occurs in 30 to 80 percent of patients in intensive care units. This cerebral impairment not only causes mental confusion and emotional disruption but also drastically increases the mortality risk of patients. A controlled circadian rhythm and sleep/wake cycle is the prerequisite for delirium prevention. This is where the new VitalMinds concept from Philips comes in.
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EXXETA AG

Gamification: facilitating a gradual return-to-play

08/06/2020

Professional athletes depend on a speedy recovery from sports injuries or surgery because their livelihood depends on their physical fitness. Returning to competition too soon after injury can have negative health consequences. Standard tests are now combined with virtual reality to determine the optimal time to return to play.
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Image: The new medical device Magnetic Particle Imaging (MPI); Copyright: IBI

Molecular Imaging: fast and reliable stroke detection

02/06/2020

After a stroke, a patient’s life depends on getting acute care at a hospital. Vital monitoring systems ensure safe and effective treatment. An innovative tomographic imaging system is designed to help prevent the patient’s risky journey to radiology and to enable bedside monitoring of cerebral blood flow.
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Image: Computer-generated image of an arborizing blood vessel; Copyright: panthermedia.net/Ugreen

Angiogenesis: light shows blood vessels the way

03/02/2020

Regenerative medicine aims to replace damage in the body with functional tissue and restore normal function. The first defense for large defects are implants made of hydrogels, designed to promote cell growth. They need their own blood supply, which is a problem when it comes to larger implants because you cannot regulate where and how the blood vessels grow - until now.
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panthermedia.net/phonlamai

A new type of endoscopy – small, easy, comfortable

22/01/2020

Patients have to undergo a gastroscopy to rule out gastrointestinal conditions. Many dread this procedure since a thin, flexible tube is being pushed through the esophagus and stomach. Ovesco Endoscopy AG has teamed up with other project partners in the nuEndo research project to develop a capsule endoscopy device that is tiny, easy to swallow and makes the test more comfortable for the patient.
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Image: cemented artificial hip endoprostheses; Copyright: panthermedia.net/coddie

Endoprostheses: regaining independence and mobility

01/01/2020

Joints can suddenly or gradually deteriorate and lose their natural strength, whether it’s due to accidents, diseases or simple wear and tear. In some of these cases, implants of artificial joints – endoprostheses - can help. As a joint replacement, they are designed to stay in the body for as long as needed and as such improve the patient’s quality of life and mobility.
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Endoprostheses: between possibility and reality

01/01/2020

When natural joints lose their ability to function, they can be completely or partially replaced by artificial joints, also called endoprostheses. Endoprostheses must be of a certain quality, as they should remain in the body as long as possible. In addition to some risks, endoprostheses can also contribute to a mobile and carefree life for young and old.
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MEDICA TECH FORUM: light-based imaging technique OCT

04/11/2019

Since its inception, MEDICA TECH FORUM has focused on the implementation of innovations and new technologies into clinical practice. 2019 marks the tenth year of the Forum. In honor of its anniversary, we will brighten things up a bit, as one of the focal points will highlight how optical coherence tomography (OCT) uses light to produce images.
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Image: Volker Bruns; Copyright: Fraunhofer ISS

Fraunhofer ISS

AI software: "iSTIX opens your world to the possibilities of digital pathology"

08/10/2019

The healthcare market offers a multitude of microscopes that make cells visible to the human eye. The same applies to AI-based software for image analysis. After taking the microscopic images, scientist are faced with large volumes of scans with usually low resolution. Yet when all aspects merge together, they open up a the world of digital pathology.
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Deep Learning Image Reconstruction – what AI looks like in clinical routine

02/09/2019

Artificial intelligence is no longer a dream of the future in medicine. Many studies and initial application examples show that it sometimes achieves better results than human physicians. At Jena University Hospital, the work with AI is already lived practice. It is the first institution in the world to use algorithms in radiological routine to reconstruct CT images.
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Image: Laboratory situation - Prof. Popp shows a young man a small object in his hand; Copyright: Leibniz-IPHT/Sven Döring

Leibniz-IPHT/Sven Döring

Tumor excision: triple imaging for unique diagnostics

08/08/2019

After their tumor has been removed, some patients have to return to the hospital to undergo surgery again. That's because the tumor was not precisely identified and was subsequently not completely removed. That's both an ethical and financial dilemma. A new surgery-adjacent procedure is designed to rapidly and accurately detect tumors.
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Image: A greenly lit laboratory device; Copyright: Sven Döring

Photonics: "We want a rapid and easy method to identify pathogens and antibiotic resistance"

01/08/2019

The medical devices value chain has gaps between academic research and industrial practice that slow down innovation processes. This also applies to time-sensitive and urgently needed products such as rapid diagnostic tests to identify resistant pathogens. At the InfectoGnostics Research Campus in Jena, partners from research and medicine team up to close these gaps.
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Image: Team Capsix with KUKA robot arm and body model; Copyright: Capsix Robotics, Lyon

Capsix Robotics, Lyon

Healthy Living thanks to robotics – KUKA Innovation Award 2019

24/06/2019

Improving technology transfer from research to industry and driving robotics development - that's the idea behind the KUKA Innovation Award. This year’s topic is "Healthy Living". Applicants from around the world were tasked with creating a robot application for healthcare settings. Now, the finalists, who will showcase their innovations at the MEDICA 2019 trade fair have been selected.
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Image: Screenshot of the VR app: a small penguin sitting on the treatment table of the MRI device; Copyright: Entertainment Computing Group, Uni DUE & LAVAlabs Moving Images

Entertainment Computing Group, Uni DUE & LAVAlabs Moving Images

Gamification: how penguins help children overcome their MRI fear

23/04/2019

It's noisy, tight and scary - that's how children feel about a magnetic resonance imaging (MRI) machine. Because they are scared, they are often too fidgety and anxious during the procedure, causing the images to blur or the scan to be stopped. Researchers have now developed a VR app called Pingunauten Trainer that’s designed to gently prepare the little patients for MRI scans.
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Image: close-up of a woman lying in an MRI device; Copyright: panthermedia.net/Craig Robinson

Brain mapping: preoperative planning with functional MRI

01/04/2019

A surgery already begins before the patient is lying on the operating table – namely with the planning. For example, if brain surgery is imminent, the brain must first be mapped. This makes the activity level of certain brain areas visible. Functional magnetic resonance imaging makes this possible.
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Image: CT scan open; Copyright: panthermedia.net/SimpleFoto

Functional imaging: a look at the command center

01/04/2019

All information from our body and the environment converges in our brain and is transformed into reactions in milliseconds. It is essential for medicine and research to know what our switching centre looks like. Functional methods are used to observe it more closely during work.
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Image: Patient during an fMRI examination; Copyright: panthermedia.net/Chris De Silver

Functional imaging: what makes the brain tick?

01/04/2019

Our brain is the command center of our body. This is where all information and impressions are collected and converted into responses and movements. Modern imaging techniques offer physicians and researchers unique insights into the actions of the human central nervous system. The functional imaging technique allows them to watch our brain in action.
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Image: Man during CT examination; Copyright: panthermedia.nt/Romaset

Stroke: 4D brain perfusion accelerates treatment

01/04/2019

In an ischaemic stroke, rapid treatment is essential. In this moment good imaging data is particularly important to enable doctors to make the best possible decision for therapy. Modern CT scanners are increasingly being used to assess stroke patients because they can show the blood flow to the brain over time.
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Picture: Woman sleeping sideways in bed with a breathing mask; Copyright: Philips GmbH

Comprehensive Treatment: It’s All About Breathing

01/03/2019

Coughing, airway obstruction, difficulty breathing: Chronic obstructive pulmonary disease (COPD) is an umbrella term used to describe progressive and currently incurable lung diseases. The innovative solutions of Philips Respironics help patients to manage each stage of the disease and their medication intake, train the respiratory system and provide respiratory support.
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Image: Dosage inhaler and stethoscope in front of a shelf; Copyright: panthermedia.net/liudmilachernetska@gmail.com

React early, breathe free – comprehensive COPD management

01/03/2019

COPD is considered the third most common cause of death worldwide and mainly affects smokers. It is not curable, but with the right combination of early diagnosis, therapy and self-management, a significant part of the quality of life can be regained. The comprehensive care is supported by various devices and technical tools. Learn more about the all-round care of COPD in our Topic of the Month.
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Image: Lung monitoring of a patient with PulmoVista 500 by Draeger; Copyright: Drägerwerk AG & Co. KGaA

Restoring Pulmonary Function

01/03/2019

People suffering from lung disease temporarily need ventilator support because they are unable to breathe naturally. Mechanical ventilation is designed to ensure the survival of these patients. The goal is to adapt the ventilator settings and tailor them the patient's specific needs and prevent lung tissue damage.
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Image: Man and woman in a laboratory presenting a multi-organ chip; Copyright: TissUse GmbH

Multi-Organ Chips – The Patients of Tomorrow?

01/02/2019

The liver, nervous tissue or the intestines: all are important human organs that have in the past been tested for their function and compatibility using animal or in vitro test methods. In recent years, TissUse GmbH, a spin-off of the Technical University of Berlin (TU Berlin), has launched multi-organ chip platforms. But that’s not all.
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Image: Cells in a Petri dish; Copyright: panthermedia.net / devserenco

Organ-on-a-chip - the mini organs of the future?

01/02/2019

So far in vitro methods and animal experiments have been used to determine the causes of diseases, research therapeutic approaches and predict the effect of drugs. Organ-on-a-chip models now offer a more accurate and ethically justifiable alternative. Find out more about the models, their advantages and future developments in our Topic of the Month.
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Image: digital capture of an eye; Copyright: panthermedia.net / cosmin momir

A digital look inside the human eye – when algorithms diagnose Diabetes

02/01/2019

Diabetes mellitus or simply diabetes has become very common and is often described as a lifestyle disease. More and more people are suffering from this chronic metabolic disorder. Next to established diagnostic procedures, digital retinal screening has shown to be successful - a promising technique that will also play an important role in the diagnosis of other diseases in the future.
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Image: Woman with diabetes and a sensor; Copyright: panthermedia.net / Click and Photo

Blood glucose monitoring of tomorrow - modern diabetes therapies

02/01/2019

There are 425 million people with diabetes in the world. Heart problems, kidney failure or blindness - these can all be consequences of the metabolic disease. Diabetes patients now have the possibility of being treated digitally.
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Image: Woman puts her arms around the retina scanner and looks smilingly to the side into the camera; Copyright: Mimo AG

Mimo AG

Collect, process, communicate – retina measurements with Mimo

19/12/2018

Continuous monitoring is an essential process with every disease. In the case of eye disorders, frequent retina measurements can facilitate early detection of deterioration to quickly initiate intervention. This calls for comprehensive care settings, easy ways to take measurements and prompt results. However, in reality, this is rarely the case.
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Image: View over the shoulders of two doctors at a screen showing a model of a heart; Copyright: panthermedia.net/Wavebreakmedia ltd

panthermedia.net/Wavebreakmedia ltd

Regenerative heart valves: from simulation to replacement

23/07/2018

Every year, more than 250,000 patients worldwide receive heart valve implants. Children require repeated replacement surgery because their bodies are still growing, the prosthetic heart valves are not. Regenerative heart valves solve this problem. Until now, we have only been able to monitor how these living implants develop in the body after the fact. Computer models now make this predictable.
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Image: AcCellerator research device at an exhibition stand; Copyright: Daniel Klaue, ZELLMECHANIK DRESDEN GmbH

Daniel Klaue, ZELLMECHANIK DRESDEN GmbH

Cells in the speed trap – diagnosis in a matter of seconds

22/06/2018

A drop of blood provides a lot of valuable information. However, it takes several hours to analyze the blood of a patient and make a diagnosis. This takes away a lot of time that's crucial for treatment. A new method intends to considerably speed up this process by testing the cells in the blood in terms of their deformability and immune response.
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Image: young woman with VR-glasses in the VR-Lab, in front of it a young man at a computer, on which a virtual heart can be seen; Copyright: Kompetenzzentrum eLearning in der Medizin Baden-Württemberg

Kompetenzzentrum eLearning in der Medizin Baden-Württemberg

VR Lab for medical students: linking theory and practice

22/03/2018

Virtual reality and medicine are increasingly mentioned in the same context. In addition to the development of applications that support the treatment of patients suffering from chronic pain and anxiety, this technology also benefits medical staff. Two months ago, the Ulm University Hospital has opened the VR Lab, where medical students can train and learn with the help of 3D organs.
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