Autonomous medical technology: independently in the body -- MEDICA - World Forum for Medicine

Image: Two men in white physicians’ coats in a hospital hallway - Dr. Philipp Ivanyi, Prof. Mohamed Omar; Copyright: Ilka Kosmalski/MHH

Ilka Kosmalski/MHH

Cancer therapy: MHH Sarcoma Center successfully DKG-certified

28/06/2022

The Sarcoma Center of the Comprehensive Cancer Center (CCC) of the MHH, which is one of the oldest in the country, has been successfully certified by the German Cancer Society (DKG). In addition to the treatment of soft tissue tumors, the center was also recognized for the treatment of bone tumors.
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Image: Device setup for a FLASH experiment consisting of many components; Copyright: Biophysics / GSI Helmholtz Center for Heavy Ion Research

Biophysics / GSI Helmholtz Center for Heavy Ion Research

New cooperation aims to further advance radiation therapy

27/06/2022

The GSI Helmholtzzentrum für Schwerionenforschung, the Technische Hochschule Mittelhessen (THM) and Varian, a Siemens Healthineers company from Palo Alto, California, intend to jointly advance medical-technical developments in the field of FLASH therapy and further pave the way to clinical application.
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Image: Young sick woman talking to a doctor during chemotherapy; Copyright: bialasiewicz

bialasiewicz

AI platform enables doctors to optimize personalized chemotherapy

21/06/2022

Based on a pilot clinical trial, close to 97% of dose recommendations by CURATE.AI were accepted by clinicians; some patients were prescribed optimal doses that were around 20% lower on average.
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Image: Tim Whelan stands at a radiation therapy machine and poses for the camera; Copyright: Georgia Kirkos/McMaster University

Georgia Kirkos/McMaster University

Radiotherapy not always needed for early breast cancer

13/06/2022

Older women with early stage breast cancer may not need radiotherapy after undergoing surgery, McMaster University researcher Timothy Whelan and his team has found.
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Image: Man in a suit and glasses poses for the camera; Copyright: Klaus Nagels

Klaus Nagels

Precise blood diagnostics improve treatment outcome for lung cancer

10/06/2022

Non-small cell lung carcinoma is a particularly aggressive type of lung cancer. Tumor cells and tumor DNA (ctDNA) in the blood of patients with the disease can be analyzed by means of liquid biopsy throughout the course of the disease.
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Image: Visualization about how researchers developed a microbubble-assisted ultrasound-guided immunotherapy; Copyright: UT Southwestern Medical Center

UT Southwestern Medical Center

Microbubble technology to enhance cancer immunotherapy

08/06/2022

Researchers at UT Southwestern have developed a first-of-its-kind ultrasound-guided cancer immunotherapy platform that delivers immune-stimulating agents to cells for the development of systemic anti-tumor immunity.
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Image: Three physicians in OR clothing work with a medical device; Copyright: USZ

USZ

Human liver treated in a machine and transplanted for the first time

07/06/2022

The multidisciplinary Zurich research team Liver4Life has succeeded in doing something during a treatment attempt that had never been achieved in the history of medicine until now: it treated an originally damaged human liver in a machine for three days outside a body and then implanted the recovered organ into a cancer patient. One year later, the patient is doing well.
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Image: A breast cancer cell captured in the process of division; Copyright: Wei Qian\National Cancer Institute

Wei Qian\National Cancer Institute

The paired perils of breast cancer and diabetes

03/06/2022

Study describes mechanism by which breast cancer suppresses insulin production, impairing blood sugar regulation and causing diabetes, which, in turn, promotes tumor growth.
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Image: Sick elderly patient using telemedicine on video call; Copyright: DC_Studio

DC_Studio

Telehealth: Performing virtual frailty exams in the home

31/05/2022

New study finds that frailty assessments are both feasible and safe when conducted virtually, increasing health care access for older adults with blood cancers.
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Image: A proctologist holds an endoscope in his hand; Copyright: romankosolapov

romankosolapov

Computer-assisted colonoscopy identifies more precancerous polyps

30/05/2022

Colonoscopies performed with computer-aided detection, or artificial intelligence, (AI) saw an increase in the overall rate of detection of adenoma, or cancerous and precancerous polyps, by 27 percent in average-risk patients.
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Image: Two men position a patient dummy between measuring devices on the floor; Copyright: Fraunhofer/Piotr Banczerowski

Fraunhofer/Piotr Banczerowski

3D-based position control in radiotherapy

24/05/2022

A research team at the Fraunhofer Institute for Applied Optics and Precision Engineering IOF has worked closely with Varian Medical Systems (Fraunhofer IOF’s industrial partner) to develop a novel system for tumor radiotherapy, which improves cancer patients’ chances of recovery. The scientists behind the project were awarded the Joseph von Fraunhofer Prize for the overall system.
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Image: Drawn schematic of a work flow in a laboratory; Copyright: Juliet Percival/MPI für Biochemie

Juliet Percival/MPI für Biochemie

New method revolutionizes cancer diagnosis

24/05/2022

A German-Danish team led by Prof. Matthias Mann has developed a ground-breaking technology called 'Deep Visual Proteomics'. This method provides researchers and clinicians with a protein read-out to understand cancer at single cell-type resolution. The technology was published in the journal Nature Biotechnology and demonstrates its potential in a first application to cancer cells.
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A diagram intended to illustrate genetic manipulation of the female reproductive tract ; Copyright: AG Chumduri

AG Chumduri

Cervix: Research progress thanks to mini organs

23/05/2022

Life-like organ replicas - so-called 3D organoids - are a good way to research disease processes. A team from the University of Würzburg has now presented a kind of blueprint for such a model of the cervix.
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Image: A three-dimensional view of cell activities of skin cancer squamous cell carcinoma.; Copyright: M. Schober/E. Fuchs, Rockefeller University

M. Schober/E. Fuchs, Rockefeller University

New method melds data to make a 3-D map of cells’ activities

20/05/2022

HZI researchers develop molecular probes to detect pathogens in clinical samples.
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Image: A woman in the bathroom is holding her stomach because of pain; Copyright: gpointstudio

gpointstudio

Nanosensor platform could advance detection of ovarian cancer

18/05/2022

Lehigh University researchers, part of multi-institution team, use the fluorescence of carbon nanotubes and machine learning to create a ‘spectral fingerprint’ of a hard-to-diagnose cancer.
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Image: Female nurse looks at results on computer; Copyright: engagestock

engagestock

New computational tool to interpret clinical significance of cancer mutations

12/05/2022

The software, called CancerVar, standardizes procedures to help researchers assess the clinical impacts of over 13 million somatic cancer mutations.
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Image: radiological image of soft tissue lesions; Copyright: NYU’s Center for Data Science

NYU’s Center for Data Science

Breast-cancer: Radiologists and AI systems show differences in screenings

06/05/2022

Radiologists and artificial intelligence systems yield significant differences in breast-cancer screenings, a team of researchers has found. Its work, which appears in the journal Nature Scientific Reports, reveals the potential value of using both human and AI methods in making medical diagnoses.
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Image: Doctor discusses lung scan with a patient; Copyright: DC_Studio

DC_Studio

Lung cancer treatment: model to predict patients with poor outcomes

04/05/2022

Moffitt Cancer Center researchers are working to improve the ability to identify patients who are at a higher risk of poor survival through radiomics, an area of science that uses imaging, such as CT scans and MRIs, to uncover tumoral patterns and characteristics that may not be easy to spot by the naked eye.
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Image: MRI scan of patient's head, neck and brain; Copyright: Nikita_Karchevskyi

Nikita_Karchevskyi

Subgroups of glioblastoma associated with disease prognosis

02/05/2022

Researchers have detected different subgroups of the brain tumour form glioblastoma, where the cancer cells’ properties depend on which cell type they originate from. The used analysis method could also separate glioblastoma patients with significant differences in survival. The findings open up for identifying specific therapeutic targets for the new subgroups of glioblastoma.
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Image: Researchers in a laboratory; Copyright: Freya Lücke, UKSH

Freya Lücke, UKSH

Leukaemia: Previously unknown risk factors in adulthood

29/04/2022

New research from the Clinical Research Unit "CATCH ALL" at Kiel University and UKSH identifies genetic causes for treatment resistance in BCP-ALL.
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Image: Linear accelerator in oncological cancer therapy; Copyright: EdVal

EdVal

Radiation therapy: Weapon against tumours, boost for the immune system

27/04/2022

Radiation therapy is a proven approach to destroying tumours. However, it is possible that it might be able to do even more in the future – namely stimulate the immune system at the same time and so fight cancer even more intensively.
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Image: 3D illustration of colon cancer; Copyright: PantherMedia  / animaxx3d

PantherMedia / animaxx3d

AI reduces miss rate of precancerous polyps in colorectal cancer screening

22/04/2022

Artificial intelligence reduced by twofold the rate at which precancerous polyps were missed in colorectal cancer screening, reported a team of international researchers led by Mayo Clinic.
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Image: A CT device; Copyright: Pressmaster

Pressmaster

Tumors partially destroyed with sound don't come back

20/04/2022

Technique pioneered in rats at the University of Michigan could improve outcomes for cancer and neurological conditions.
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Image: Gray scale image of tissue; Copyright: Referenz-Screening-Einheit Münster-Nord

Referenz-Screening-Einheit Münster-Nord

Breast tomosynthesis: Cancer detected more often than with standard mammography

19/04/2022

By now, breast cancer is the most frequent tumor disease worldwide. This is why in Germany women aged 50 and over are offered systematic early detection examinations – so-called mammography screening. The Clinic for Radiology at the University of Münster conducts research in the field of innovative imaging technologies and their impact on the efficiency of detecting breast cancer.
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Image: demonstration of a gel that rapidly self-heals after injection to form a solid-like gel; Copyright: Abigail K. Grosskopf

Abigail K. Grosskopf

Simple delivery method enhances promising cancer treatment

13/04/2022

One cutting-edge cancer treatment exciting researchers today involves collecting and reprogramming a patient’s T cells – a special set of immune cells – then putting them back into the body ready to detect and destroy cancerous cells. Although effective for widespread blood cancers like leukemia, this method rarely succeeds at treating solid tumors.
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Image: An illustration of a male body with the pancreas highlighted; Copyright: PantherMedia  / magicmine

PantherMedia / magicmine

AI model may predict elevated pancreatic cancer risk using EHR

13/04/2022

An artificial intelligence (AI) model trained using sequential health information derived from electronic health records identified a subset of individuals with a 25-fold risk of developing pancreatic cancer within three to 36 months
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Image: A laser microscope on a brain model; Copyright: Fraunhofer

Fraunhofer

A new laser scanning microscope improves cancer cell detection

11/04/2022

Fraunhofer researchers have developed a very fast technology for determining whether a tumor has been fully removed — before the patient even leaves the operating theater. Using a combination of laser scanning microscopy and fluorescent tumor markers, doctors can detect any remaining cancer cells immediately after operations.
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Image: A bluely colored tissue sample with bright green dots; Copyright: Team Wolfgang Kastenmüller/Universität Würzburg

Team Wolfgang Kastenmüller/Universität Würzburg

Immune system 'sentinel' cells key to immunotherapy

05/04/2022

The presence of dendritic cells, so-called 'sentinel' immune cells, is vital to maintain and regulate the balance of the body's immune response. Researchers have discovered an essential role of these cells in the treatment of cancer and severe viral infections.
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Image: Two surgeons are standing at the control console of an OR device; Copyright: Christian Morawe/Universitätsmedizin Magdeburg

Christian Morawe/Universitätsmedizin Magdeburg

Histotripsy: fighting tumors with microbubbles

08/09/2021

Focused ultrasound waves create microbubbles in a fluid – a phenomenon called cavitation. In a current study, this process is used to destroy liver tumors and metastases.
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Image: Two small, angular-shaped, electrical devices that are held with tweezers; Copyright: Fraunhofer EMFT/Bernd Müller

Tumor therapy: drug delivery pump instead of injection

01/02/2021

Drugs always have undesired side effects. Cytostatics are powerful drugs used to treat cancer. They reach almost all cells in the body, killing healthy cells as well as cancer cells in the process. A targeted delivery to the specific cellular site would be a gentler treatment.
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Image: Artist’s rendering of small star-shaped machines between red blood cells; Copyright: PantherMedia/Michael Osterrieder

Autonomous medical devices: running well in your body

01/02/2021

In theory, autonomous medical technologies can be used in a diagnostic or therapeutic capacity inside the body under certain conditions. This may not sound like a new invention at first. After all, implantable cardioverter-defibrillators have monitored and fixed abnormal heart rhythm for many years.
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Image: Laboratory situation - Prof. Popp shows a young man a small object in his hand; Copyright: Leibniz-IPHT/Sven Döring

Leibniz-IPHT/Sven Döring

Tumor excision: triple imaging for unique diagnostics

08/08/2019

After their tumor has been removed, some patients have to return to the hospital to undergo surgery again. That's because the tumor was not precisely identified and was subsequently not completely removed. That's both an ethical and financial dilemma. A new surgery-adjacent procedure is designed to rapidly and accurately detect tumors.
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Image: Small brown mole on the back of a hand; Copyright: panthermedia.net/Mario Hahn

panthermedia.net/Mario Hahn

Early detection: Tattoo signals cancer – and more

09/07/2018

People who are not ill and do not show any symptoms typically do not visit the doctor. And while most people know that preventive medical checkups for cancer, for example, are important, they still avoid them. They tend to be very hesitant because the doctor might detect a serious illness. In the future, a new type of implant could make it easier to go to a screening test.
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Image: DermaFC developed by Magnosco; Copyright: Magnosco

Magnosco

A startup makes melanin glow: skin cancer diagnostics with Magnosco

09/04/2018

When a skin lesion is suspected to exhibit malignant changes, it is usually promptly removed. However, not all cases require an excision of the affected tissue. The startup company Magnosco has developed a procedure that uses a laser to support the diagnosis and early detection of malignant melanoma.
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Image: a container with the nutrient medium for cancer cells; Copyright: Dr. Markus Wehland

Dr. Markus Wehland

Cells in space – extraterrestrial approaches in cancer research

22/02/2018

Here on Earth, all experiments are bound by gravitation. Yet, freed from gravity's grip, tumor cells, for example, behave in an entirely different way. As part of the "Thyroid Cancer Cells in Space" project by the University of Magdeburg, smartphone-sized containers carrying poorly differentiated thyroid cancer cells are sent into space.
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