Organ-on-a-chip - the mini organs of the future? -- MEDICA - World Forum for Medicine

Image: A hand with a glove holding a biopsy needle with an attached cable; Copyright: Aalto University

21st century medical needles for high-tech cancer diagnostics

29/04/2021

Modern medicine needs better quality samples than traditional biopsy needles can provide. Ultrasonically oscillating needles can improve treatment and reduce discomfort.
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Image: Schematic illustrations of solid-phase multiplex RPA; Copyright: Korea Institute of Materials Science (KIMS)

Respiratory viral pathogens caught on-site

16/04/2021

The research team also developed a 3D plasmonic array chip for multiplex molecular detections: a chip that can simultaneously analyze 8 pathogens (4 bacteria and 4 viruses).
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Image: Microscopic image colored in orange and black; Copyright: Salk Institute/Waitt Advanced Biophotonics Core

New method could democratize deep learning-enhanced microscopy

18/03/2021

Deep learning is a potential tool for scientists to glean more detail from low-resolution images in microscopy, but it is often difficult to gather enough baseline data to train computers in the process. Now, a new method developed by scientists at the Salk Institute could make the technology more accessible - by taking high-resolution images, and artificially degrading them.
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Image: A grid of square microwells filled with colored cell clusters; Copyright: Khademhosseini Lab

Multicellular liver-on-a-chip for modeling fatty liver disease

15/03/2021

Non-alcoholic fatty liver disease (NAFLD) is the most prevalent chronic liver disease worldwide. It is found in 30% of people in developed countries and occurs in approximately 25% of people in the United States. Risk factors for the disease include obesity, diabetes, high cholesterol and poor eating habits, although this does not exclude individuals without these risk factors.
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Image: A team of six researchers; Copyright: L. Brian Stauffer

3D microscopy clarifies understanding of body's immune response to obesity

24/02/2021

Researchers who focus on fat know that some adipose tissue is more prone to inflammation-related comorbidities than others, but the reasons why are not well understood. Thanks to a new analytical technique, scientists are getting a clearer view of the microenvironments found within adipose tissue associated with obesity.
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Image: A cell cluster with green and red colored cells; Copyright: Universität Leipzig

Cancer cells become fluidized and squeeze through tissue

22/02/2021

Working with colleagues from Germany and the US, researchers at Leipzig University have achieved a breakthrough in research into how cancer cells spread. In experiments, the team of biophysicists led by Professor Josef Alfons Käs, Steffen Grosser and Jürgen Lippoldt demonstrated for the first time how cells deform in order to move in dense tumor tissues and squeeze past neighboring cells.
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Image: UV Visual Lift; Copyright: by UVentions

Hygiene: Smart protection against pathogens like the coronavirus

23/03/2020

Germs such as bacteria, viruses or pathogenic fungi can spread from one person to another through direct contact when we shake hands or touch objects. People touch door handles and push elevator buttons in public places and constantly move in and out of spaces. Regular manual high-level disinfection is practically impossible. UVentions GmbH has found an intelligent solution for this problem.
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Image: Two screens with picture of the circulatory system in a catheter laboratory; Copyright: panthermedia.net/sudok1

MEDICA TECH FORUM: light-based imaging technique OCT

04/11/2019

Since its inception, MEDICA TECH FORUM has focused on the implementation of innovations and new technologies into clinical practice. 2019 marks the tenth year of the Forum. In honor of its anniversary, we will brighten things up a bit, as one of the focal points will highlight how optical coherence tomography (OCT) uses light to produce images.
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Image: Laboratory situation - Prof. Popp shows a young man a small object in his hand; Copyright: Leibniz-IPHT/Sven Döring

Tumor excision: triple imaging for unique diagnostics

08/08/2019

After their tumor has been removed, some patients have to return to the hospital to undergo surgery again. That's because the tumor was not precisely identified and was subsequently not completely removed. That's both an ethical and financial dilemma. A new surgery-adjacent procedure is designed to rapidly and accurately detect tumors.
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Image: A greenly lit laboratory device; Copyright: Sven Döring

Photonics: "We want a rapid and easy method to identify pathogens and antibiotic resistance"

01/08/2019

The medical devices value chain has gaps between academic research and industrial practice that slow down innovation processes. This also applies to time-sensitive and urgently needed products such as rapid diagnostic tests to identify resistant pathogens. At the InfectoGnostics Research Campus in Jena, partners from research and medicine team up to close these gaps.
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Image: Graphic rendering of several cells in a petri dish; Copyright: panthermedia.net/dani3315

Organ-on-a-chip systems: limited validity?

01/02/2019

Organ-on-a-chip systems are technically a great enhancement of medical research because they facilitate testing of active ingredients on cell cultures in the chambers of a plastic chip. This replaces animal testing and improves patient safety. That being said, they are not a true-to-life replication of the human body and can only simulate a few functions and activities.
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Image: Maria Driesel and her colleagues from inveox next to the new device; Copyright: Astrid Eckert

Pathology 4.0 – inveox automates laboratory processes

22/08/2018

Mix-ups, contamination and sample loss – most errors in pathology happen when specimen are received. Countless samples arrive daily at the laboratory, while the sample entry process is very monotonous. As a result, the work is inefficient. The start-up company inveox has now developed a system that automates the processes in the pathology laboratory, thus making them more efficient.
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