Infectious diseases – the laboratory races pathogens -- MEDICA - World Forum for Medicine

Image: retina layers displayed in a diagram; Copyright: Knowledge Technology Institute, UCM

Retina: areas change in mild Alzheimer's disease

19.09.2019

Researchers at the Complutense University of Madrid (UCM) have identified changes in retinal layer thickness, inflammation or thinning in patients with mild Alzheimer's disease, confirming that the retina is one of the most important biomarkers for early diagnosis of the disease.
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Image: electronic platforms in different shapes; Copyright: Muhammad Hussain

Wearables: reconfigurable electronics promising innovations

11.09.2019

Medical implants of the future may feature reconfigurable electronic platforms that can morph in shape and size dynamically as bodies change or transform to relocate from one area to monitor another within our bodies.
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Imaging: reducing lung cancer mortality

10.09.2019

A combination of the EarlyCDT-Lung Test followed by CT imaging in Scottish patients at risk for lung cancer resulted in a significant decrease in late stage diagnosis of lung cancer and may decrease lung cancer specific mortality, according to research presented at IASLC 2019 World Conference on Lung Cancer hosted by the International Association for the Study of Lung Cancer (IASLC).
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Imaging: eye scan makes diseases visible at an early stage

09.09.2019

According to the World Health Organization, in four out of five cases age-related vision disorders could be avoided if they were diagnosed at an early stage. A European team of scientists, including the Leibniz Institute of Photonic Technology (Leibniz IPHT) in Jena, has researched a new method that will enable doctors to better detect such eye diseases in the future.
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Image: graphic that describes the workflow of Radiomics Analysis for IHC Indicators; Copyright: American Journal of Roentgenology (AJR)

AI: radiomics model to predict thyroid nodules

02.09.2019

Machine learning models can be trained to extract immunohistochemical (IHC) characteristics from the CT scans of patients with suspected thyroid nodules, and these IHC characteristics can then be utilized to significantly improve thyroid nodule diagnoses.
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 Image: reasearcher in laboratory; Copyright: panthermedia.net/kasto

Islet-on-a-chip: miniature device for diabetes research

30.08.2019

In a study led by Harvard University's Kevin Kit Parker, microfluidics and human, insulin-producing beta cells have been integrated in an "Islet-on-a-Chip". The new device makes it easier for scientists to screen insulin-producing cells before transplanting them into a patient, test insulin-stimulating compounds, and study the fundamental biology of diabetes.
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Image: colorful figure showing an important part of the protein with contact pairs; Copyright: Ines Reinartz, KIT

AI: predicting the protein structure

15.08.2019

Proteins are biological high-performance machines. They can be found in every cell and play an important role in human blood coagulation or as main constituents of hairs or muscles. The function of these molecular tools is obvious from their structure.
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Image: man - Muhammed Murtaza - in the laboratory; Copyright: Courtesy of TGen

Blood test: liquid biopsy improves breast cancer diagnostics

14.08.2019

A new type of blood test for breast cancer could help avoid thousands of unnecessary surgeries and otherwise precisely monitor disease progression, according to a study led by the Translational Genomics Research Institute (TGen) and Mayo Clinic in Arizona.
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Wearables: motion sensors could save unborn babies

14.08.2019

The thump, thump of a baby's heartbeat is a milestone in any pregnancy. Now, researchers at Stevens Institute of Technology have developed a technique that could allow expectant parents to hear their baby's heartbeat continuously at home with a non-invasive and safe device that is potentially more accurate than any fetal heartrate monitor currently available in the market.
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Image: PET imaging using the radiotracers FDG and florbetapir for analysis; Copyright: Penn Medicine

Imaging: brain's glucose consumption as a marker

08.08.2019

While the presence of beta-amyloid plaques in the brain may be a hallmark of Alzheimer's disease, giving patients an amyloid PET scan is not an effective method for measuring their cognitive function, according to a new study from researchers in the Perelman School of Medicine at the University of Pennsylvania and Thomas Jefferson University.
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Image: Bacteria in the gut are pulled into the helical channels by an osmotic 'pump' in the pill.; Copyright: Nano Lab, Tufts University

Diagnostics: 3D-printed pill samples aid diagnosis and treatment

29.07.2019

The pill is the first known working device capable of non-invasively and accurately assessing the profile of bacterial species inhabiting any stage of the gastrointestinal tract. The ability to profile bacterial species inhabiting the gut could have important implications for conditions that affect and are affected by the intestinal microbiome.
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Blood test: may also identify people at most TB risk

23.07.2019

A new study conducted by researchers in Leicester and Nottingham has shown the potential for a new blood test to not only diagnose human tuberculosis (TB) but also identify those at most risk of developing the disease.
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Two new algorithms identify patients at risk of HIV

22.07.2019

Two new studies developed algorithms that can identify patients who are at risk of acquiring HIV and may benefit from preventive care.
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Urological diagnosis: electronic tongues detect bladder cancer

22.07.2019

A team from the Polytechnic University of Valencia (UPV), the La Fe Health Research Institute (IIS-La Fe) and the Centre for Biomedic Research in the fields of Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN), dependant of the Carlos III Health Institute, has developed a new non-invasive method to help with the early detection and monitoring of bladder cancer.
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Image: Wrist with smartwatch, which measures the pulse rate; Copyright: panthermedia.net / Lev Dolgachov

mHealth: Atrial fibrillation detection – App supports heart health

08.05.2019

Atrial fibrillation is the most common type of persistent cardiac arrhythmia (irregular heart rhythm). Researchers estimate that 1.8 million Germans are presently affected by this disease. The condition is difficult to diagnose, frequently goes undetected and may result in a stroke. A new smartwatch medical app is designed to help patients detect atrial fibrillation before it’s too late.
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All-round care for COPD: diagnosis, treatment, self-management

01.03.2019

COPD affects more than 200 million people in the world. Those affected by this chronic pulmonary disease are often slow to notice the symptoms and get a medical diagnosis. This results in secondary complications and high medical costs. That's why an early diagnosis, comprehensive treatment, and frequent monitoring are very important. Various devices and tools support this all-round care.
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Picture: Woman sleeping sideways in bed with a breathing mask; Copyright: Philips GmbH

Comprehensive Treatment: It’s All About Breathing

01.03.2019

Coughing, airway obstruction, difficulty breathing: Chronic obstructive pulmonary disease (COPD) is an umbrella term used to describe progressive and currently incurable lung diseases. The innovative solutions of Philips Respironics help patients to manage each stage of the disease and their medication intake, train the respiratory system and provide respiratory support.
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Image: Cell cultivation in a Petri dish; Copyright: panthermedia.net / matej kastelic

Organ-on-a-chip – Organs in miniature format

01.02.2019

In vitro processes and animal tests are used to develop new medications and novel therapeutic approaches. However, animal testing raises important ethical concerns. Organ-on-a-chip models promise to be a feasible alternative. In a system the size of a smartphone, organs are connected using artificial circulation.
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Image: Man and woman in a laboratory presenting a multi-organ chip; Copyright: TissUse GmbH

Multi-Organ Chips – The Patients of Tomorrow?

01.02.2019

The liver, nervous tissue or the intestines: all are important human organs that have in the past been tested for their function and compatibility using animal or in vitro test methods. In recent years, TissUse GmbH, a spin-off of the Technical University of Berlin (TU Berlin), has launched multi-organ chip platforms. But that’s not all.
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Hybrid Imaging – Two Views of the Lungs

25.01.2019

CT scan, MRI or X-ray: All these methods allow doctors to see inside the body - including inside the lungs - and make a diagnosis. The clinic for Nuclear Medicine at the RWTH Aachen University Hospital uses a state-of-the-art gamma camera that combines SPECT and CT.
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Image: Woman at her desk holding her back; Copyright: panthermedia.net/Andrey Popov

AI ensures dynamic sitting

22.01.2019

Whether in the office, at school or behind the wheel: we spend a lot of time sitting and often stay in the same position for too long. The possible side effects are stiffness, back problems and pain. The SensA-Chair smart seating solution combats decreased mobility and ensures dynamic sitting.
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A digital look inside the human eye – when algorithms diagnose Diabetes

02.01.2019

Diabetes mellitus or simply diabetes has become very common and is often described as a lifestyle disease. More and more people are suffering from this chronic metabolic disorder. Next to established diagnostic procedures, digital retinal screening has shown to be successful - a promising technique that will also play an important role in the diagnosis of other diseases in the future.
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Image: Woman puts her arms around the retina scanner and looks smilingly to the side into the camera; Copyright: Mimo AG

Collect, process, communicate – retina measurements with Mimo

19.12.2018

Continuous monitoring is an essential process with every disease. In the case of eye disorders, frequent retina measurements can facilitate early detection of deterioration to quickly initiate intervention. This calls for comprehensive care settings, easy ways to take measurements and prompt results. However, in reality, this is rarely the case.
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From algorithm to rapid test – Artificial Intelligence classifies blood cells

21.11.2018

Our blood reveals a lot about our physical health. The shape of our blood cells sheds light on several hereditary diseases for example. For a diagnosis, the cells must first be examined under the microscope and categorized into a specific cell class. We met with Dr. Stephan Quint and Alexander Kihm of the Institute of Physics at the Saarland University, who explained how this classification works.
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See, experience, learn: what's new at MEDICA 2018

02.11.2018

It's time: the world's largest medical trade fair opens its doors from 12 to 15 November. More than 5,000 international exhibitors will present their new innovative products and applications. Frums, conferences and special shows will feature exciting specialist lectures and discussions that will give you an insight into electromedicine, laboratory medicine, medical technology and diagnostics.
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Image: diagnosis of the lung; Copyright: panthermedia.net/Sergey Nivens

With modern imaging supplies: A look into the lung

01.10.2018

Thanks to various imaging supplies, it is possible to make the inside of the body accessible for diagnostics, research and treatment. The lung, one of the most important human organs for survival, is also examined in this way. In our Topic of the Month, we looked at how doctors are getting a closer look at the lung, how the procedures differ, and which ones will be available in the near future.
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Image: Radiology assistant presses a button at the front of a CT; Copyright: panthermedia.net/Arne Trautmann

Lung cancer: Screening with low-Dose CT scans

01.10.2018

Lung cancer is one of the most common and deadliest cancers. The symptoms tend to be non-specific, often causing its detection to be too late. Currently, there is no comprehensive screening. This could change with the use of low-dose CT scans. It should be noted that this is not just an issue of technical feasibility. A screening test must also make sense from a health policy perspective.
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Image: Older couple is sitting next to each other, using their smartphones; Copyright: panthermedia.net/Fabrice Michaudeau

Neurology: Early detection of Parkinson’s disease with app and data?

01.08.2018

Big Data is often likened to finding the proverbial needle in a haystack: Large volumes of data contain patterns that hold the answer to a particular question. The trick is to gather meaningful data and identify patterns. The i-PROGNOSIS research project shows how smart devices and an app team up to automatically collect data without disturbing the user.
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Early detection: Tattoo signals cancer – and more

09.07.2018

People who are not ill and do not show any symptoms typically do not visit the doctor. And while most people know that preventive medical checkups for cancer, for example, are important, they still avoid them. They tend to be very hesitant because the doctor might detect a serious illness. In the future, a new type of implant could make it easier to go to a screening test.
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Image: DermaFC developed by Magnosco; Copyright: Magnosco

A startup makes melanin glow: skin cancer diagnostics with Magnosco

09.04.2018

When a skin lesion is suspected to exhibit malignant changes, it is usually promptly removed. However, not all cases require an excision of the affected tissue. The startup company Magnosco has developed a procedure that uses a laser to support the diagnosis and early detection of malignant melanoma.
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Image: A hand touches a smartphone camera that is measuring the heart rate with an app; Copyright: Preventicus GmbH

"Preventicus Heartbeats": An app that's a clinically validated medical device

01.12.2017

Stroke is the second leading cause of death in the world. Yet many incidences of stroke are preventable since they are frequently associated with an undetected abnormal heart rhythm. In this case, patients can benefit from using the clinically validated "Preventicus Heartbeats" app, which measures and documents the heart rhythm with a smartphone camera.
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Image: Surgeons during surgery; Copyright: UKR

Acute kidney injury: Early detection thanks to biomarker

08.11.2017

Major surgeries in the abdominal region often result in kidney injury in patients. Meanwhile, the clinical manifestations don't present until one or two days after the procedure. This causes physicians to lose valuable time to treat patients. The University Hospital Regensburg has researched a new concept for the treatment of kidney injuries for several years.
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Image: Collage made of two images, one show a round, transparent plastic disc with micro channels, one shows a plastic chip; Copyright: Hahn-Schickard, Image Bernd Müller

Prenatal diagnosis: genetic analysis using droplet PCR

24.07.2017

A new analysis method that uses fetal DNA extracted from the mother’s blood is designed to non-invasively reach a prenatal diagnosis of genetic disorders in a child. A task force of the Hahn Schickard Society for Applied Research is an active part of the "ANGELab" project and co-developed this diagnostic procedure.
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Image: Graphic representation of Europe with small figures depicting the population; Copyright: panthermedia.net/Takahase Segundo

Hospital-acquired infections: pathogens know no borders

03.04.2017

Many aspects are uniformly regulated in Europe, however, hospital hygiene and MRSA prevention, for example, are not. The Netherlands plays a pioneering role in the fight against hospital-acquired infections. The country is an often-cited role model. But can other countries simply adopt the same system? And what makes it so different? MEDICA asked expert Prof. Alexander W. Friedrich.
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Pneumonia in Children: Ultrasound or X-Rays?

08.03.2017

Pneumonia is the most frequent respiratory disease in children and can even cause death. That is why it is extremely important to make an accurate diagnosis as quickly as possible. If this requires imaging tests, normally X-rays are taken. But there is an alternative: ultrasound.
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Collect Data? Utilize Data! – The Blessings of Big Data

01.03.2017

Genome data, MRI images, and blood test results – data collected in the medical sector is not only very heterogeneous but also extremely extensive. However, it is important to not only collect this data but to also utilize it. After all, processed, linked and analyzed data provides many opportunities in research, hospital management and ultimately also for the individual patient.
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