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Single-use tests: sensitivity and easy use combined for diagnostics
12.12.2019
Diagnostic testing usually takes some time and a sterile environment to get the results. To cut down on the costs and effort spend on these tasks there are different diagnostic tests. One of them are single-use tests offered by SensDx S.A. The technology behind them not only makes the process faster and easier, but provides the opportunity to expand into home use in the future as well.
Tissue Engeneering: new in-vitro 3D neural tissue model
12.12.2019
Researchers at the University of Illinois at Urbana-Champaign have successfully used stem cells to engineer living biohybrid nerve tissue to develop 3D models of neural networks with the hopes of gaining a better understanding of how the brain and these networks work.
Endoscopy: new less invasive ultra-miniaturized endoscope
10.12.2019
Johns Hopkins engineers have created a new lens-free ultra-miniaturized endoscope, the size of a few human hairs in width, that is less bulky and can produce higher quality images.
Drug information system: shows how cancer cells react to drugs
10.12.2019
A new technique overcomes several limitations of typical high-throughput chemical screens conducted on cell samples. Such screens are commonly used to try to discover new cancer drugs, and in many other biomedical applications.
Machine learning: imaging boosts colon cancer diagnosis
09.12.2019
Colorectal cancer is the second most common type of cancer worldwide, with about 90% of cases occurring in people 50 or older. Arising from the inner surface, or muscosal layer, of the colon, cancerous cells can penetrate through the deeper layers of the colon and spread to other organs. Left untreated, the disease is fatal.
"Virtual biopsy": to accurately diagnose pancreatic cysts
09.12.2019
Research from doctors at The Ohio State University Wexner Medical Center finds a new "virtual biopsy" allows them to definitively diagnose cysts in the pancreas with unprecedented accuracy. This means they can eliminate precancerous cysts and potentially save lives.
Blood cells: AI-driven classification
13.11.2019
Every day, millions of single blood cells are evaluated for disease diagnostics in medical laboratories and clinics. Most of this repetitive task is still done manually by trained cytologists who inspect cells in stained blood smears and classify. This process suffers from classification variability and requires the presence and expertise of a trained cytologist.
Biosensor: technology created for stem cells
12.11.2019
A Rutgers-led team has created better biosensor technology that may help lead to safe stem cell therapies for treating Alzheimer's and Parkinson's diseases and other neurological disorders.
Biosensor: made from a dangerous toxin
30.10.2019
Some types of bacteria have the ability to punch holes into other cells and kill them. They do this by releasing specialized proteins called "pore-forming toxins" (PFTs) that latch onto the cell's membrane and form a tube-like channel that goes through it. This hole across the membrane is called a pore. Punctured by multiple PFTs, the target cell self-destructs.
3D-printing: finds cancer cells
29.10.2019
Finding a handful of cancer cells hiding among billions of blood cells in a patient sample can be like finding a needle in a haystack. In a new approach enabled by 3D-printed cell traps, researchers are removing the hay to expose the cancer cells.
Cells: gut health influences brain health
25.10.2019
Over the last two decades, scientists have observed a clear link between autoimmune disorders and a variety of psychiatric conditions. For example, people with autoimmune disorders such as inflammatory bowel disease (IBD), psoriasis and multiple sclerosis may also have depleted gut microbiota and experience anxiety, depression and mood disorders.
Algorithm: machine learning's pigenetic drug discovery
24.10.2019
Sanford Burnham Prebys scientists create a machine-learning algorithm that automates high-throughput screens of epigenetic medicines. Machine learning's powerful ability to detect patterns in complex data is revolutionizing how we drive, how we diagnose disease and now, how we discover new drugs.
Bioprinting: living cells in a 3D printer
22.10.2019
Tissue growth and the behavior of cells can be controlled and investigated particularly well by embedding the cells in a delicate 3D framework. This is achieved using additive 3D printing methods - so called "bioprinting" techniques. However, some methods are very imprecise or only allow a very short time window in which the cells can be processed without being damaged.
Gene: new therapeutic target for pulmonary fibrosis
11.10.2019
Researchers in Japan have identified a genetic mutation that causes idiopathic pulmonary fibrosis (IPF) by killing the cells lining the lung's airways. The study, which will be published October 10 in the Journal of Experimental Medicine (JEM), suggests that protecting these cells by inhibiting a cell death pathway called necroptosis could be a new therapeutic approach to treating IPF.
Cells: epilepsy disrupting "brake cells" functions
07.10.2019
In some forms of epilepsy, the function of certain "brake cells" in the brain is presumed to be disrupted. This may be one of the reasons why the electrical malfunction is able to spread from the point of origin across large parts of the brain. A current study by the University of Bonn, in which researchers from Lisbon were also involved, points in this direction.
Cells: mechanism for the formation of new blood vessels
24.09.2019
Researchers from Uppsala University have revealed for the first time a mechanism for how new blood vessels are formed and have shown the importance of this mechanism for embryo survival and organ function. The results could be developed to control the formation of new blood vessels in different diseases. The new study is published in the journal EMBO Reports.
mHealth: Atrial fibrillation detection – App supports heart health
08.05.2019
Atrial fibrillation is the most common type of persistent cardiac arrhythmia (irregular heart rhythm). Researchers estimate that 1.8 million Germans are presently affected by this disease. The condition is difficult to diagnose, frequently goes undetected and may result in a stroke. A new smartwatch medical app is designed to help patients detect atrial fibrillation before it’s too late.
A digital look inside the human eye – when algorithms diagnose Diabetes
02.01.2019
Diabetes mellitus or simply diabetes has become very common and is often described as a lifestyle disease. More and more people are suffering from this chronic metabolic disorder. Next to established diagnostic procedures, digital retinal screening has shown to be successful - a promising technique that will also play an important role in the diagnosis of other diseases in the future.
Lung cancer: Screening with low-Dose CT scans
01.10.2018
Lung cancer is one of the most common and deadliest cancers. The symptoms tend to be non-specific, often causing its detection to be too late. Currently, there is no comprehensive screening. This could change with the use of low-dose CT scans. It should be noted that this is not just an issue of technical feasibility. A screening test must also make sense from a health policy perspective.
A startup makes melanin glow: skin cancer diagnostics with Magnosco
09.04.2018
When a skin lesion is suspected to exhibit malignant changes, it is usually promptly removed. However, not all cases require an excision of the affected tissue. The startup company Magnosco has developed a procedure that uses a laser to support the diagnosis and early detection of malignant melanoma.
"Preventicus Heartbeats": An app that's a clinically validated medical device
01.12.2017
Stroke is the second leading cause of death in the world. Yet many incidences of stroke are preventable since they are frequently associated with an undetected abnormal heart rhythm. In this case, patients can benefit from using the clinically validated "Preventicus Heartbeats" app, which measures and documents the heart rhythm with a smartphone camera.
Hospital-acquired infections: pathogens know no borders
03.04.2017
Many aspects are uniformly regulated in Europe, however, hospital hygiene and MRSA prevention, for example, are not. The Netherlands plays a pioneering role in the fight against hospital-acquired infections. The country is an often-cited role model. But can other countries simply adopt the same system? And what makes it so different? MEDICA asked expert Prof. Alexander W. Friedrich.