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Endoscopy: new less invasive ultra-miniaturized endoscope
10.12.2019
Johns Hopkins engineers have created a new lens-free ultra-miniaturized endoscope, the size of a few human hairs in width, that is less bulky and can produce higher quality images.
Drug information system: shows how cancer cells react to drugs
10.12.2019
A new technique overcomes several limitations of typical high-throughput chemical screens conducted on cell samples. Such screens are commonly used to try to discover new cancer drugs, and in many other biomedical applications.
Machine learning: imaging boosts colon cancer diagnosis
09.12.2019
Colorectal cancer is the second most common type of cancer worldwide, with about 90% of cases occurring in people 50 or older. Arising from the inner surface, or muscosal layer, of the colon, cancerous cells can penetrate through the deeper layers of the colon and spread to other organs. Left untreated, the disease is fatal.
Tissue Engineering: new ways to avoid animal testing
26.11.2019
Around 60 international experts met on November 7 at the Fraunhofer Institute for Silicate Research ISC in Wuerzburg to report on the state of the art in the field of 3D tissue models and prevention of animal experiments in the development of pharmaceuticals and medical devices.
Cells: blocking metastasis-promoting enzyme
15.11.2019
In a breakthrough with important implications for the future of immunotherapy for breast cancer, UC San Francisco scientists have found that blocking the activity of a single enzyme can prevent a common type of breast cancer from spreading to distant organs.
Cells: oxygen-starved tumor cells promoting cancer spread
08.11.2019
Using cells from human breast cancers and mouse breast cancer models, researchers at the Johns Hopkins Kimmel Cancer Center say they have significant new evidence that tumor cells exposed to low-oxygen conditions have an advantage when it comes to invading and surviving in the bloodstream.
Cardiac diagnostics – prompt and personalized
08.11.2019
If physicians suspect an acute myocardial infarction, they first order an ECG. This test is very established and allows cardiologists to quickly diagnose acute heart attacks – though the test does not detect less common heart attack symptoms. So far, those patients had to wait up to twelve hours before a heart attack could be accurately diagnosed or ruled out. But things are about the change.
Pulverize kidney stones: like windshield-cracking raindrops
07.11.2019
A plane has to be going pretty fast for a mere raindrop to crack its windshield, but it can happen. Now, new models of the physics behind the improbable feat may just help doctors crack kidney stones to pieces.
Radiotherapy: breaking the stroma barrier
22.10.2019
Pancreatic cancer is one of the leading causes of cancer related deaths worldwide. Patients with pancreatic cancer often receive chemotherapy or radiation therapy, which are not always effective and can have toxic side effects. The method may offer an effective treatment for pancreatic cancer with fewer side effects in surrounding organs.
Cells: potential liver cancer treatment
10.10.2019
Liver cancer is the second leading cause of cancer-related deaths worldwide. The most common primary liver cancer in adults is known as hepatocellular carcinoma (HCC), and accounts for approximately 780.000 deaths every year. Even with advanced surgical treatments or transplantation, the 5-year survival rate for HCC patients remains poor due to frequent recurrence.
Blood vessels: overly permeable
09.10.2019
In Germany alone there are around 400,000 patients who suffer from chronic inflammatory bowel diseases. For the first time, researchers have discovered that dysfunctions in blood vessels play a significant role in the development of such diseases. In experimental model systems, the progression of the disease slowed down significantly by eliminating these dysfunctions.
Regenerative medicine: biofabrication for multiple tissues
01.10.2019
Organs, muscles and bones are composed of multiple types of cells and tissues that are carefully organized to carry out a specific function. For example, kidneys are able to filter waste from the blood because of how their specialized cells and tissues are arranged. Disrupting this organization dramatically affects how cells and tissues do their job effectively.
Cardiac Tissue Engineering: a heart out of the Petri dish
23.09.2019
For patients waiting for donor organs, every day can mean the difference between life and death. Making things even more complicated is the fact that not every organ is a compatible match with the patient. It would mean enormous progress if we could grow organs from the patient's own cells in the lab. That's why patients with heart disease place big hope in tissue engineering.
Restoring Pulmonary Function
01.03.2019
People suffering from lung disease temporarily need ventilator support because they are unable to breathe naturally. Mechanical ventilation is designed to ensure the survival of these patients. The goal is to adapt the ventilator settings and tailor them the patient's specific needs and prevent lung tissue damage.
Gentle medication for the little ones – with every breath
22.02.2019
According to the WHO, ten percent of babies worldwide are born prematurely. Since most organs of these tiny babies have not fully developed yet, it can quickly lead to complications and disorders and most notably affect the lungs of the premature infants. What's more, infections require gentle treatment, as the preemies themselves are fragile and susceptible – making this a challenging situation.
Organ-on-a-chip – Organs in miniature format
01.02.2019
In vitro processes and animal tests are used to develop new medications and novel therapeutic approaches. However, animal testing raises important ethical concerns. Organ-on-a-chip models promise to be a feasible alternative. In a system the size of a smartphone, organs are connected using artificial circulation.
Multi-Organ Chips – The Patients of Tomorrow?
01.02.2019
The liver, nervous tissue or the intestines: all are important human organs that have in the past been tested for their function and compatibility using animal or in vitro test methods. In recent years, TissUse GmbH, a spin-off of the Technical University of Berlin (TU Berlin), has launched multi-organ chip platforms. But that’s not all.
AI ensures dynamic sitting
22.01.2019
Whether in the office, at school or behind the wheel: we spend a lot of time sitting and often stay in the same position for too long. The possible side effects are stiffness, back problems and pain. The SensA-Chair smart seating solution combats decreased mobility and ensures dynamic sitting.
Lung Imaging – Keeping the Respiratory System Healthy
05.10.2018
Many people have damaged or suboptimally functioning lungs. An accurate diagnosis and subsequent treatment are vital to protect this life-sustaining organ. Modern imaging solutions help physicians and patients understand what happens inside the lungs.
Regenerative heart valves: from simulation to replacement
23.07.2018
Every year, more than 250,000 patients worldwide receive heart valve implants. Children require repeated replacement surgery because their bodies are still growing, the prosthetic heart valves are not. Regenerative heart valves solve this problem. Until now, we have only been able to monitor how these living implants develop in the body after the fact. Computer models now make this predictable.
Organ Care System: treatment under extreme conditions
08.05.2018
Multidrug-resistant organisms that are treated with a dosage that exceeds the regular dose a hundred times and at temperatures of over 40 degrees Celsius – the human organism is unable to handle it. Yet if the diseased organ is treated outside of the body, extreme conditions are an option. For the first time, physicians have succeeded in treating a severe case of pneumonia by using the OCS.
Precision surgery thanks to informative hyperspectral imaging
08.02.2018
When body tissue is reconnected during a tumor operation in the gastrointestinal tract, surgeons need information about the current state of these so-called anastomoses. The new, non-invasive hyperspectral imaging technology now makes it possible to measure the crucial parameters during surgery and thereby increase surgical precision.
Acute kidney injury: Early detection thanks to biomarker
08.11.2017
Major surgeries in the abdominal region often result in kidney injury in patients. Meanwhile, the clinical manifestations don't present until one or two days after the procedure. This causes physicians to lose valuable time to treat patients. The University Hospital Regensburg has researched a new concept for the treatment of kidney injuries for several years.
A look at the medicine of tomorrow – At MEDICA Preview in Hamburg
08.11.2017
Every year in September, MEDICA Preview takes place at the University Hospital Hamburg-Eppendorf. It is intended to give visitors, exhibitors and the trade press a foretaste of MEDICA in November and tomorrow's medicine. This year, we were on the scene with our camera to learn more about opto genetics, smart hospitals and the support of patients with multiple organ failure.
Irreversible Electroporation – Last hope for liver cancer patients
24.04.2017
Liver cancer is the fifth most common malignant tumor in the world. The tumor can be removed through surgery or by utilizing thermal ablation techniques. If a treatment with conservative methods is no longer possible, there is an alternative: irreversible electroporation (IRE). The effectiveness of this method was now confirmed by a clinical study.