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Covid-19: protective canopy prevents infection
19/01/2021
The risk of infection with SARS-CoV-2 is particularly high indoors. This is because, in addition to smear and droplet infection, infection via aerosols that accumulate and spread in the air is also possible there. Sufficient air exchange or air purification help to prevent this. The protective canopy developed by Fraunhofer IBP also follows such an approach.
Microfluidic system may unravel how novel pathogens attack
02/12/2020
To develop effective therapeutics against pathogens, scientists need to first uncover how they attack host cells. An efficient way to conduct these investigations on an extensive scale is through high-speed screening tests called assays.
New device offers faster way to detect antibiotic-resistant bacteria
01/12/2020
Bacterial infections have become one of the biggest health problems worldwide, and a recent study shows that COVID-19 patients have a much greater chance of acquiring secondary bacterial infections, which significantly increases the mortality rate.
Detecting bacteria with fluorescent nanosensors
01/12/2020
Researchers from Bochum, Göttingen, Duisburg and Cologne have developed a new method for detecting bacteria and infections. They use fluorescent nanosensors to track down pathogens faster and more easily than with established methods.
X-ray study explores potential of hepatitis C drugs to treat COVID-19
17/11/2020
Experiments led by researchers at the Department of Energy's Oak Ridge National Laboratory have determined that several hepatitis C drugs can inhibit the SARS-CoV-2 main protease, a crucial protein enzyme that enables the novel coronavirus to reproduce.
Algorithm identifies previously undetected cancer driver genes
13/11/2020
A new study, led by researchers from the University of California, Irvine, has deepened the understanding of epigenetic mechanisms in tumorigenesis and revealed a previously undetected repertoire of cancer driver genes. The study was published this week in Science Advances.
Rapid test can ID unknown causes of infections throughout the body
12/11/2020
UC San Francisco scientists have developed a single clinical laboratory test capable of zeroing in on the microbial miscreant afflicting patients hospitalized with serious infections in as little as six hours -- irrespective of what body fluid is sampled, the type or species of infectious agent, or whether physicians start out with any clue as to what the culprit may be.
Machine learning models to predict critical illness and mortality in COVID-19 patients
11/11/2020
Mount Sinai researchers have developed machine learning models that predict the likelihood of critical events and mortality in COVID-19 patients within clinically relevant time windows. The new models outlined in the study could aid clinical practitioners at Mount Sinai and across the world in the care and management of COVID-19 patients.
Biomarker combination predicts kidney injury in critically ill children
02/11/2020
Researchers at the University of Liverpool have identified a unique method of identifying the early signs of a potentially serious condition known as Acute Kidney Injury (AKI).
Disinfection: let mist do the work
02/11/2020
Healthcare settings require sharp weapons to fight both hospital-acquired infections and pathogens like SARS-CoV-2. Besides protective equipment, regular room disinfection is one of them. But they require time and are also prone to error if done manually. Fully automated solutions are needed to relief hospital staff from this exhausting work and perform it reliably. So, why not fog the room?
Laboratory work: the right personal protective equipment is crucial
01/04/2020
When working with infectious materials and organisms in the laboratory, safe handling and appropriate training are of utmost importance. Another central component is personal protective equipment designed to prevent contact with tissue, liquids and aerosols and protect the wearer.
BSL-4 laboratories: highest levels of safety and protection
01/04/2020
Laboratories are sectioned into four biosafety levels to dictate the precautions required to isolate dangerous biological agents. The highest level of biological safety, BSL-4, is perhaps the most well-known when we think of containing pathogens and microbes. However, the fewest number of laboratories actually fall into the BSL-4 category.
The safe laboratory – protection through technology
01/04/2020
When biomedical researchers or diagnosticians work with potentially contagious materials like cell cultures, blood or tissue, they need absolute protection from pathogens. Both safety measures in the workspace and the correct tools and materials are key here. Learn in our Topic of the Month what is important for protection in the lab and what a safe laboratory looks like.
Laboratory safety: infection prevention in the work area
01/04/2020
What goes in, must not come out - and must also not cause harm to anyone working inside the lab. That's perhaps a nice way of summing up "laboratory safety" in one sentence - at least wherever pathogens are handled in biological and medical settings. The necessary laboratory safety precautions primarily depend on what is waiting "inside".
Hygiene: Smart protection against pathogens like the coronavirus
23/03/2020
Germs such as bacteria, viruses or pathogenic fungi can spread from one person to another through direct contact when we shake hands or touch objects. People touch door handles and push elevator buttons in public places and constantly move in and out of spaces. Regular manual high-level disinfection is practically impossible. UVentions GmbH has found an intelligent solution for this problem.
Endoprotheses: between possibility and reality
01/01/2020
When natural joints lose their ability to function, they can be completely or partially replaced by artificial joints, also called endoprotheses. Endoprotheses must be of a certain quality, as they should remain in the body as long as possible. In addition to some risks, endoprotheses can also contribute to a mobile and carefree life for young and old.
APRICOT-project: implant "help(s) patients heal themselves"
01/01/2020
Today, people tend to live longer, while an increasing number of patients suffer from osteoarthritis. Even younger generations are now at a higher risk of getting osteoarthritis due to the frequent use of mobile devices. The EU research project APRICOT aims to develop a novel type of implant for the treatment of osteoarthritis of the hands – helping patients heal themselves.
Endoprosthetic surgery: modern and traditional approaches
01/01/2020
Surgery is required if you need an artificial joint. Patients and doctors must select the type of surgery that’s best suited and choose between robot-assisted, traditional or minimally invasive surgical approaches. Post-operative risks should be kept to a minimum, while benefits should outweigh any possible complications.
Endoprotheses: regaining independence and mobility
01/01/2020
Joints can suddenly or gradually deteriorate and lose their natural strength, whether it’s due to accidents, diseases or simple wear and tear. In some of these cases, implants of artificial joints – endoprostheses - can help. As a joint replacement, they are designed to stay in the body for as long as needed and as such improve the patient’s quality of life and mobility.
Medicine at the pulse of time: Innovations and trends at MEDICA 2019
04/11/2019
Soon, the world's largest trade fair for medical technology will open its doors again: More than 5.000 exhibitors will present their newest products and ideas at MEDICA from 18 to 21 November. You will not only meet well-known companies here, but also lots of young start-ups. Or, you can visit the MEDICA forums and conferences to experience a rich program of lectures and discussions.
Antibiotic resistance: technical tricks against pathogens
01/08/2019
An untreatable infection is a nightmare for physicians and potentially life-threatening to the patient. Unfortunately, more and more pathogens emerge that are resistant to drugs, especially antibiotics. We need to use our drugs smartly and come up with technical solutions as well to prevent our weapons from blunting in the future.
Last-resort antibiotics: "We can identify carbapenemases within half an hour"
01/08/2019
Antibiotic resistance is modern medicine's greatest challenge. Some bacteria only respond to a handful of antibiotics, prompting hospitals to spend a lot of time finding an effective drug. That’s why it is critical for physicians to rapidly identify antibiotic resistance to avoid ineffective treatments.
Photonics: "We want a rapid and easy method to identify pathogens and antibiotic resistance"
01/08/2019
The medical devices value chain has gaps between academic research and industrial practice that slow down innovation processes. This also applies to time-sensitive and urgently needed products such as rapid diagnostic tests to identify resistant pathogens. At the InfectoGnostics Research Campus in Jena, partners from research and medicine team up to close these gaps.
Combating antibiotic resistance: One step ahead through technology
01/08/2019
Antibiotic resistance is on the rise in all parts of the world, complicating medical treatment of serious bacterial infections in patients. The World Health Organization estimates that approximately 33,000 people die each year from antibiotic-resistant bacteria in Europe alone. Bacteria that are resistant to multiple or even all known antibiotics pose an ever-increasing threat.
Cells in the speed trap – diagnosis in a matter of seconds
22/06/2018
A drop of blood provides a lot of valuable information. However, it takes several hours to analyze the blood of a patient and make a diagnosis. This takes away a lot of time that's crucial for treatment. A new method intends to considerably speed up this process by testing the cells in the blood in terms of their deformability and immune response.
Organ Care System: treatment under extreme conditions
08/05/2018
Multidrug-resistant organisms that are treated with a dosage that exceeds the regular dose a hundred times and at temperatures of over 40 degrees Celsius – the human organism is unable to handle it. Yet if the diseased organ is treated outside of the body, extreme conditions are an option. For the first time, physicians have succeeded in treating a severe case of pneumonia by using the OCS.