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Image: enzymes; Copyright: PantherMedia / Luka Culig

Gut enzyme could lead to new disease biomarker

12/08/2020

Enzymes used by bacteria to break down mucus in the gut could provide a useful biomarker for intestinal diseases, according to new research published in Nature Communications. Researchers at the University of Birmingham and Newcastle University have successfully identified and characterised one of the key enzymes involved in this process.
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Image: Blood is taken from the finger of an elderly woman; Copyright: PantherMedia/belchonok

Blood test shows promise in the diagnosis of Alzheimer's

07/08/2020

A new blood test demonstrated remarkable promise in discriminating between persons with and without Alzheimer's disease and in persons at known genetic risk may be able to detect the disease as early as 20 years before the onset of cognitive impairment, according to a large international study published in Journal of the American Medical Association (JAMA).
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Image: A child in the ICU next to a ventilator; Copyright: PantherMedia/beerkoff1

Lab profiles differentiate MIS-C from COVID-19 in children

06/08/2020

Findings show that MIS-C is a post-infectious syndrome distinct from Kawasaki disease and may help guide treatment decisions.
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Non-invasive biomarkers to diagnose infant urinary tract obstruction

24/07/2020

One in every 500 babies is born with a condition called ureteropelvic junction obstruction, an obstruction of the ureter that prevents urine from flowing from one or both of the kidneys into the bladder. Diagnosed prenatally, UPJO can cause urinary tract infections; it can also result in chronic kidney disease and an increased risk for cardiovascular disease in later life.
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Revealing lung disease with exhaled biomarkers

21/07/2020

Using specialized nanoparticles, MIT engineers have developed a way to monitor pneumonia or other lung diseases by analyzing the breath exhaled by the patient. In a study of mice, the researchers showed that they could use this system to monitor bacterial pneumonia, as well as a genetic disorder of the lungs called alpha-1 antitrypsin deficiency.
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Image: A black wearable device that sticks to a person's arm; Copyright: Yichao Zhao/UCLA

Adhesive film turns smartwatch into biochemical health monitoring system

25/06/2020

UCLA engineers have designed a thin adhesive film that could upgrade a consumer smartwatch into a powerful health-monitoring system. The system looks for chemical indicators found in sweat to give a real-time snapshot of what is happening inside the body. A study detailing the technology was published in the journal of Science Advances.
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Biomarkers show clear signs of brain injury with severe COVID-19

23/06/2020

Certain patients who receive hospital care for coronavirus infection (COVID-19) exhibit clinical and neurochemical signs of brain injury, a University of Gothenburg study shows. In even moderate COVID-19 cases, finding and measuring a blood-based biomarker for brain damage proved to be possible.
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Image: Black and white microscope image of a patch with a spiky surface; Copyright: Khademhosseini lab

Extraction of skin interstitial fluid using microneedle patches

05/06/2020

Researchers at the Terasaki Institute enhance tool for extraction of samples used in monitoring patient health.
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Image: Tube being filled in a laboratory setting; Copyright: UEF/ Raija Törrönen

Boost cancer treatment with new LAT1 inhibitor

18/05/2020

Researchers at the University of Eastern Finland have developed a new and promising drug compound for the treatment of cancer that inhibits natural amino acids from entering cancer cells. Since amino acids are essential for the growth and division of cancer cells, the new LAT1 inhibitor makes it possible to inhibit their growth. The study was published in the journal Apoptosis.
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Cardiac diagnostics – prompt and personalized

08/11/2019

If physicians suspect an acute myocardial infarction, they first order an ECG. This test is very established and allows cardiologists to quickly diagnose acute heart attacks – though the test does not detect less common heart attack symptoms. So far, those patients had to wait up to twelve hours before a heart attack could be accurately diagnosed or ruled out. But things are about the change.
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Image: Small brown mole on the back of a hand; Copyright: panthermedia.net/Mario Hahn

Early detection: Tattoo signals cancer – and more

09/07/2018

People who are not ill and do not show any symptoms typically do not visit the doctor. And while most people know that preventive medical checkups for cancer, for example, are important, they still avoid them. They tend to be very hesitant because the doctor might detect a serious illness. In the future, a new type of implant could make it easier to go to a screening test.
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Personalized cancer medicine – Best possible treatment with TherapySelect

30/04/2018

Medicine is getting more and more personalized. This is particularly interesting for oncology, since a cancer is as individual as the respective patient. When choosing a therapy, both the characteristics of the tumor and the personal characteristics of the patient must be considered. To see exactly what this looks like, we visited the diagnostics company TherapySelect, based in Heidelberg.
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Image: A group of physicians is holding large colorful puzzle pieces in their hands and is putting them together; Copyright: panthermedia.net/Andriy Popov

Personalized medicine: a paradigm shift is gaining momentum

01/03/2018

Personalized medicine does not follow a "one-size-fits-all" treatment approach but emphasizes a "tailor-made" paradigm, meaning a treatment is customized to each individual person's case. For patients, this increases the chances of treatment success and means fewer side effects. While the approach originates in the field of oncology, it is now also increasingly applied to other disease patterns.
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