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Image: The microfluidic multiplex biosensor carries proteins attached to a polymer film that recognize the antibiotics; Copyright: Patrick Seeger/Universität Freiburg

Antibiotic levels measurable in breath for first time


Freiburg researchers are testing a biosensor for personalized dosing of medications. Antibiotic sensor validated in animal model for blood, saliva, urine and breath samples and the risk of resistant strains of bacteria can also be reduced.
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Image: Biotin-labeled secretory protein profiles in supernatants of hepatocyte cell lines, HepG2 and AML12, and mouse plasma; Copyright: KAIST (Korea Advanced Institute of Science an Technology)

The Dynamic Tracking of Tissue-Specific Secretory Proteins


Researchers have presented a method for profiling tissue-specific secretory proteins in live mice.
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Image: Heat-map, where red shows high levels of a compound, and blue shows low levels of a compounds, reveals the link between certain metabolites and dementia; Copyright: Okinawa Institute of Science

Signs of dementia are written in the blood, reveals new study


Scientists in Japan have identified metabolic compounds within the blood that are associated with dementia.
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Image: Drawing inspiration from nature, a team of international scientists have invented a smart device for personalized skin care modeled after the male diving beetle; Copyright: McGill University

A skin crawling treatment for acne


Drawing inspiration from nature, a team of international scientists have invented a smart device for personalized skin care modeled after the male diving beetle. This tool collects and monitors body fluids while sticking to the skin’s surface, paving the way for more accurate diagnostics and treatment for skin diseases and conditions like acne.
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Image: Senior grabs her heart in pain; Copyright: PantherMedia/ Kzenon (YAYMicro)

New study provides insight into tailoring exercise therapy to each heart failure patient


Researchers from the Osaka City University (OCU) Graduate School of Medicine have shown that patients who underwent a cardiopulmonary exercise test and showed an increased in oxidative stress had a poor prognosis.
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Image: a woman putting a liquor in a test tube; Copyright: PantherMedia / alexraths

New blood test improves prostate cancer screening


Researchers at Karolinska Institutet in Sweden published a study in The Lancet Oncology, which shows that the addition of a novel blood test, the Stockholm3 test, can reduce the number of MRIs performed by a third while further preventing the detection of minor, low-risk tumours.
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Image: a researcher holding a test tube to the camera; Copyright: Dustin Hays, National Eye Institute

NIH scientists develop faster COVID-19 test


Scientists at the National Institutes of Health (NIH) have developed a new sample preparation method to detect SARS-Cov-2, the virus that causes COVID-19. The method bypasses extraction of the virus' genetic RNA material, simplifying sample purification and potentially reducing test time and cost.
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Image: Blood is taken from the arm of a patient; Copyright: PantherMedia/

Test predicts COVID-19 severity, could help with hospital triage


During the height of the pandemic, some hospitals were overwhelmed with patients seeking treatment for COVID-19. This situation could happen again during future outbreaks, especially with SARS-CoV-2 variants of concern on the rise.
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Image: The heels of a newborn with the marks of two blood pricks; Copyright: PantherMedia/antibydni

Biomarkers: newborn screening for epilepsy in sight


The door has finally opened on screening newborn babies for pyridoxine-dependent epilepsy (PDE), a severe inherited metabolic disorder. This screening promises to enable better and earlier treatment of the disease.
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Image: A hand grips an instrument with two silver levers; Copyright: Paulo Barbosa de Freitas Júnior

Diabetes: research paves the way to early diagnosis of neuropathy


Diabetics exert less force to hold an object than people with other diseases that affect the nervous system. Grip force is a key behavioral biomarker to detect incipient diabetic neuropathy.
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Image: Three men with music instruments - Manfred Hecking, Karl Mechtler, Peter Pichler; Copyright: Mehdi Khadraoui/IMP

Hitting the right note in dialysis care


Patients with malfunctioning kidneys often need dialysis to rid their blood of unwanted molecules and excess water. Personalizing the settings of dialysis for each patient is crucial for their health, but it is complicated and error-prone. A group of Viennese scientists was awarded a competitive grant to develop a precision medicine approach to dialysis treatment.
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Image: A man and a woman in a laboratory - Julia Schipke, Christian Mühlfeld; Copyright: Karin Kaiser/MHH

MHH fills important gap in lung research


For the first time, a team of scientists clearly demonstrates the existence of lipofibroblasts in human electron microscope.
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Image: Diagram of a human lung; Copyright: PantherMedia / Wasant (YAYMicro)

Potential marker for success of immunotherapy in the treatment of lung cancer


In a paper just published in "Science Translational Medicine", a MedUni Vienna research group led by Herwig Moll (Center for Physiology and Pharmacology) identified a potential marker for the success of immunotherapy in lung cancer patient and explained the underlying molecular processes.
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Image: A group of researchers is discussing a chemical structural formula in front of a whiteboard; Copyright: PantherMedia/depositedhar

Intelligent implants: when the material is the key to the solution


Today we use implants to stabilize or compensate for injuries inside the body and to aid in the healing process. Implants cannot act autonomously and treat the patient if they deem it necessary. However, it is just a matter of time before this happens because research on intelligent implant materials that respond to stimuli is on the cusp of a breakthrough.
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Image: A woman sits on a couch and blows into a measuring device; Copyright: Bosch

Vivatmo me: monitor your asthma treatment at home


Allergic asthma is a chronic disease that makes regular monitoring essential to keep it under control. This is the only way to determine whether the prescribed medication is effective or whether the patient needs a treatment adjustment. Vivatmo me is a breath analyzer device for home use and helps keep asthma patients safe and confident between visits to the doctor.
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Image: Blood sample labelled

Cardiac diagnostics – prompt and personalized


If physicians suspect an acute myocardial infarction, they first order an ECG. This test is very established and allows cardiologists to quickly diagnose acute heart attacks – though the test does not detect less common heart attack symptoms. So far, those patients had to wait up to twelve hours before a heart attack could be accurately diagnosed or ruled out. But things are about the change.
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Image: Small brown mole on the back of a hand; Copyright: Hahn

Early detection: Tattoo signals cancer – and more


People who are not ill and do not show any symptoms typically do not visit the doctor. And while most people know that preventive medical checkups for cancer, for example, are important, they still avoid them. They tend to be very hesitant because the doctor might detect a serious illness. In the future, a new type of implant could make it easier to go to a screening test.
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Photo: Preview picture of video

Personalized cancer medicine – Best possible treatment with TherapySelect


Medicine is getting more and more personalized. This is particularly interesting for oncology, since a cancer is as individual as the respective patient. When choosing a therapy, both the characteristics of the tumor and the personal characteristics of the patient must be considered. To see exactly what this looks like, we visited the diagnostics company TherapySelect, based in Heidelberg.
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Image: A group of physicians is holding large colorful puzzle pieces in their hands and is putting them together; Copyright: Popov

Personalized medicine: a paradigm shift is gaining momentum


Personalized medicine does not follow a "one-size-fits-all" treatment approach but emphasizes a "tailor-made" paradigm, meaning a treatment is customized to each individual person's case. For patients, this increases the chances of treatment success and means fewer side effects. While the approach originates in the field of oncology, it is now also increasingly applied to other disease patterns.
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