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Image: Female nurse looks at results on computer; Copyright: engagestock

engagestock

New computational tool to interpret clinical significance of cancer mutations

12/05/2022

The software, called CancerVar, standardizes procedures to help researchers assess the clinical impacts of over 13 million somatic cancer mutations.
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Image: radiological image of soft tissue lesions; Copyright: NYU’s Center for Data Science

NYU’s Center for Data Science

Breast-cancer: Radiologists and AI systems show differences in screenings

06/05/2022

Radiologists and artificial intelligence systems yield significant differences in breast-cancer screenings, a team of researchers has found. Its work, which appears in the journal Nature Scientific Reports, reveals the potential value of using both human and AI methods in making medical diagnoses.
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Image: Doctor discusses lung scan with a patient; Copyright: DC_Studio

DC_Studio

Lung cancer treatment: model to predict patients with poor outcomes

04/05/2022

Moffitt Cancer Center researchers are working to improve the ability to identify patients who are at a higher risk of poor survival through radiomics, an area of science that uses imaging, such as CT scans and MRIs, to uncover tumoral patterns and characteristics that may not be easy to spot by the naked eye.
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Image: MRI scan of patient's head, neck and brain; Copyright: Nikita_Karchevskyi

Nikita_Karchevskyi

Subgroups of glioblastoma associated with disease prognosis

02/05/2022

Researchers have detected different subgroups of the brain tumour form glioblastoma, where the cancer cells’ properties depend on which cell type they originate from. The used analysis method could also separate glioblastoma patients with significant differences in survival. The findings open up for identifying specific therapeutic targets for the new subgroups of glioblastoma.
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Image: Researchers in a laboratory; Copyright: Freya Lücke, UKSH

Freya Lücke, UKSH

Leukaemia: Previously unknown risk factors in adulthood

29/04/2022

New research from the Clinical Research Unit "CATCH ALL" at Kiel University and UKSH identifies genetic causes for treatment resistance in BCP-ALL.
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Image: Linear accelerator in oncological cancer therapy; Copyright: EdVal

EdVal

Radiation therapy: Weapon against tumours, boost for the immune system

27/04/2022

Radiation therapy is a proven approach to destroying tumours. However, it is possible that it might be able to do even more in the future – namely stimulate the immune system at the same time and so fight cancer even more intensively.
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Image: 3D illustration of colon cancer; Copyright: PantherMedia  / animaxx3d

PantherMedia / animaxx3d

AI reduces miss rate of precancerous polyps in colorectal cancer screening

22/04/2022

Artificial intelligence reduced by twofold the rate at which precancerous polyps were missed in colorectal cancer screening, reported a team of international researchers led by Mayo Clinic.
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Image: A CT device; Copyright: Pressmaster

Pressmaster

Tumors partially destroyed with sound don't come back

20/04/2022

Technique pioneered in rats at the University of Michigan could improve outcomes for cancer and neurological conditions.
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Image: Gray scale image of tissue; Copyright: Referenz-Screening-Einheit Münster-Nord

Referenz-Screening-Einheit Münster-Nord

Breast tomosynthesis: Cancer detected more often than with standard mammography

19/04/2022

By now, breast cancer is the most frequent tumor disease worldwide. This is why in Germany women aged 50 and over are offered systematic early detection examinations – so-called mammography screening. The Clinic for Radiology at the University of Münster conducts research in the field of innovative imaging technologies and their impact on the efficiency of detecting breast cancer.
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Image: An illustration of a male body with the pancreas highlighted; Copyright: PantherMedia  / magicmine

PantherMedia / magicmine

AI model may predict elevated pancreatic cancer risk using EHR

13/04/2022

An artificial intelligence (AI) model trained using sequential health information derived from electronic health records identified a subset of individuals with a 25-fold risk of developing pancreatic cancer within three to 36 months
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Image: demonstration of a gel that rapidly self-heals after injection to form a solid-like gel; Copyright: Abigail K. Grosskopf

Abigail K. Grosskopf

Simple delivery method enhances promising cancer treatment

13/04/2022

One cutting-edge cancer treatment exciting researchers today involves collecting and reprogramming a patient’s T cells – a special set of immune cells – then putting them back into the body ready to detect and destroy cancerous cells. Although effective for widespread blood cancers like leukemia, this method rarely succeeds at treating solid tumors.
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Image: A laser microscope on a brain model; Copyright: Fraunhofer

Fraunhofer

A new laser scanning microscope improves cancer cell detection

11/04/2022

Fraunhofer researchers have developed a very fast technology for determining whether a tumor has been fully removed — before the patient even leaves the operating theater. Using a combination of laser scanning microscopy and fluorescent tumor markers, doctors can detect any remaining cancer cells immediately after operations.
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Image: A bluely colored tissue sample with bright green dots; Copyright: Team Wolfgang Kastenmüller/Universität Würzburg

Team Wolfgang Kastenmüller/Universität Würzburg

Immune system 'sentinel' cells key to immunotherapy

05/04/2022

The presence of dendritic cells, so-called 'sentinel' immune cells, is vital to maintain and regulate the balance of the body's immune response. Researchers have discovered an essential role of these cells in the treatment of cancer and severe viral infections.
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Image: Comparative image of the ink, more diffuses on the left, significantly less on the right ; Copyright: Jordan Yaron, Ph.D.

Jordan Yaron, Ph.D.

An improved ink for colon tattoos

28/03/2022

The colon might be the last place people would consider getting a tattoo, but endoscopic tattooing is an important medical technique for marking colorectal lesions for surgery or follow-up.
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Image: four ultrasound images of an ovary; Copyright: Radiological Society of North America

Radiological Society of North America

Researchers use ultrasound to predict ovarian cancer

24/03/2022

The appearance of ovarian lesions on ultrasound is an effective predictor of cancer risk that can help women avoid unnecessary surgery, according to a new study published in the journal Radiology.
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Image: Dongkyun Kang and a smartphone confocal microscope; Copyright: Mueller, S./Wintergerst

Kris Hanning / University of Arizona Health Sciences

UArizona engineer leads $1M project to fight vision loss

17/03/2022

Biomedical engineering and optical sciences professor DK Kang is developing a way to diagnose and treat corneal ulcers that's eight times cheaper and 20 times faster than today's gold standard.
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Image: Georgia Tech researcher Gabe Kwong poses for the camera Copyright: Georgia Tech photo

Georgia Tech photo

Biosensors for quick assessment of cancer treatment

16/03/2022

Immune checkpoint blockade (ICB) inhibitors have transformed the treatment of cancer and have become the frontline therapy for a broad range of malignancies. It’s because they work better than the previous standard of care.
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Image: A male scientist in a white coat and with protective glasses in operating a tall white laboratory device – Lukas Gehrke; Copyright: Empa

Empa

Nanomedicine: Gentler tumor treatment

15/03/2022

Radiation therapy is one of the cornerstones of cancer therapy. However, some types of tumor respond little or hardly at all to radiation. If it were possible to make tumor cells more sensitive, treatment would be more effective and gentler. Empa and ETH Zurich researchers have now succeeded in using metal oxide nanoparticles as "radiosensitizers" – and in producing them on an industrial scale.
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Image: Doctor sitting at the desk with a patient and explaining a prostate exam ; Copyright: PantherMedia / imagepointfr

PantherMedia / imagepointfr

New risk algorithm would improve screening for prostate cancer

11/03/2022

Calculating a person’s risk of developing prostate cancer using results from two blood markers would improve the accuracy of screening for the disease, reports a new study led by a UCL (University College London) researcher.
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Image: Three Men in white gowns poses for the camera ; Copyright: Penn Medicine

Penn Medicine

Grant to study ultra-fast, high-dose flash radiation therapy

04/03/2022

Researchers to study best methods for administering emerging form of radiotherapy treatment with shorter duration and frequency
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Image: Illustration of a bacterial structure: ectocervical, stratified squamous organoids; Copyright: University of Würzburg

University of Würzburg

Cancer: When viruses and bacteria cooperate

03/03/2022

Infections with several pathogens simultaneously increase the risk of cervical cancer—these results from a study conducted on artificial 3D tissue models at the University of Wuerzburg.
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Image: BioServe's Brian Medaugh and Dr. Luis Zea preparing the cells for integration into the flight hardware; Copyright: Image courtesy of Ivan Castro

Image courtesy of Ivan Castro

MicroQuin to launch cancer research to space station

24/02/2022

An investigation from biotechnology startup MicroQuin launching to the International Space Station (ISS) on Northrop Grumman’s 17th Commercial Resupply Services (CRS) aims to better understand the onset and progression of cancer.
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Image: An image of protein molecules; Copyright: PantherMedia / animaxx3d

PantherMedia / animaxx3d

Artificial intelligence can help to study protein complexes

21/02/2022

Researchers at Martin Luther University Halle-Wittenberg (MLU) and the European Molecular Biology Laboratory in Hamburg have developed a new method for studying proteins
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Image: Woman touches a painful spot on her stomach ; Copyright: PantherMedia / Andriy Popov

PantherMedia / Andriy Popov

Mayo Clinic researchers develop model to predict treatment response in gastric cancer

17/02/2022

A study by researchers at Mayo Clinic Cancer Center in Florida is validating the use of genomic sequencing to predict the likelihood that patients with gastric cancer will derive benefit from chemotherapy or from immunotherapy. The study is published in Nature Communications.
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Image: Two surgeons are standing at the control console of an OR device; Copyright: Christian Morawe/Universitätsmedizin Magdeburg

Christian Morawe/Universitätsmedizin Magdeburg

Histotripsy: fighting tumors with microbubbles

08/09/2021

Focused ultrasound waves create microbubbles in a fluid – a phenomenon called cavitation. In a current study, this process is used to destroy liver tumors and metastases.
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Image: Artist’s rendering of small star-shaped machines between red blood cells; Copyright: PantherMedia/Michael Osterrieder

Autonomous medical devices: running well in your body

01/02/2021

In theory, autonomous medical technologies can be used in a diagnostic or therapeutic capacity inside the body under certain conditions. This may not sound like a new invention at first. After all, implantable cardioverter-defibrillators have monitored and fixed abnormal heart rhythm for many years.
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Image: Two small, angular-shaped, electrical devices that are held with tweezers; Copyright: Fraunhofer EMFT/Bernd Müller

Tumor therapy: drug delivery pump instead of injection

01/02/2021

Drugs always have undesired side effects. Cytostatics are powerful drugs used to treat cancer. They reach almost all cells in the body, killing healthy cells as well as cancer cells in the process. A targeted delivery to the specific cellular site would be a gentler treatment.
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Image: Laboratory situation - Prof. Popp shows a young man a small object in his hand; Copyright: Leibniz-IPHT/Sven Döring

Leibniz-IPHT/Sven Döring

Tumor excision: triple imaging for unique diagnostics

08/08/2019

After their tumor has been removed, some patients have to return to the hospital to undergo surgery again. That's because the tumor was not precisely identified and was subsequently not completely removed. That's both an ethical and financial dilemma. A new surgery-adjacent procedure is designed to rapidly and accurately detect tumors.
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Image: Small brown mole on the back of a hand; Copyright: panthermedia.net/Mario Hahn

panthermedia.net/Mario Hahn

Early detection: Tattoo signals cancer – and more

09/07/2018

People who are not ill and do not show any symptoms typically do not visit the doctor. And while most people know that preventive medical checkups for cancer, for example, are important, they still avoid them. They tend to be very hesitant because the doctor might detect a serious illness. In the future, a new type of implant could make it easier to go to a screening test.
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Image: DermaFC developed by Magnosco; Copyright: Magnosco

Magnosco

A startup makes melanin glow: skin cancer diagnostics with Magnosco

09/04/2018

When a skin lesion is suspected to exhibit malignant changes, it is usually promptly removed. However, not all cases require an excision of the affected tissue. The startup company Magnosco has developed a procedure that uses a laser to support the diagnosis and early detection of malignant melanoma.
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Image: a container with the nutrient medium for cancer cells; Copyright: Dr. Markus Wehland

Dr. Markus Wehland

Cells in space – extraterrestrial approaches in cancer research

22/02/2018

Here on Earth, all experiments are bound by gravitation. Yet, freed from gravity's grip, tumor cells, for example, behave in an entirely different way. As part of the "Thyroid Cancer Cells in Space" project by the University of Magdeburg, smartphone-sized containers carrying poorly differentiated thyroid cancer cells are sent into space.
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