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Image: laboratory technology; Copyright: panthermedia.net/Robert Przybysz

Analyser system: Epigenomic technology combats disease

11.12.2019

Much remains unknown about diseases and the way our bodies respond to them, in part because the human genome is the complete DNA assembly that makes each person unique. A Virginia Tech professor and his team of researchers have created new technology to help in understanding how the human body battles diseases.
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 Image: illustration of the ConvPath software workflow; Copyright: UTSW

Software tool: AI helps doctors identify cancer cells

11.12.2019

UT Southwestern researchers have developed a software tool that uses artificial intelligence to recognize cancer cells from digital pathology images - giving clinicians a powerful way of predicting patient outcomes.
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Image: sci-Plex technique; Copyright: panthermedia.net/Wavebreakmedia (YAYMicro)

Drug information system: shows how cancer cells react to drugs

10.12.2019

A new technique overcomes several limitations of typical high-throughput chemical screens conducted on cell samples. Such screens are commonly used to try to discover new cancer drugs, and in many other biomedical applications.
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Image: PR-OCT imaging; Copyright: Zhu Lab

Machine learning: imaging boosts colon cancer diagnosis

09.12.2019

Colorectal cancer is the second most common type of cancer worldwide, with about 90% of cases occurring in people 50 or older. Arising from the inner surface, or muscosal layer, of the colon, cancerous cells can penetrate through the deeper layers of the colon and spread to other organs. Left untreated, the disease is fatal.
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Image: A physician is holding a plastic cup for urine samples; Copyright: panthermedia.net/terovesalainen

Diagnostics: New home urine test for prostate cancer

02.12.2019

A simple urine test under development for prostate cancer detection can now use urine samples collected at home - according to new research from University of East Anglia and the Norfolk and Norwich University Hospital.
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Image: examples of histopathology in the datasets used in the analyses; Copyright: Lisanne L. de Boer, Esther Kho et al.

Imaging: ability to characterize healthy and non-healthy tissue

29.11.2019

In an article published in the peer-reviewed SPIE publication Journal of Biomedical Optics (JBO), "Influence of neoadjuvant chemotherapy on diffuse reflectance spectra of tissue in breast surgery specimens," research observed across 92 ex vivo breast specimens suggests that there is little to no impact on the optical signatures of breast tissue after neoadjuvant chemotherapy.
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Image: graphic illustration of breast cancer; Copyright: panthermedia.net/decade3d

Cells: blocking metastasis-promoting enzyme

15.11.2019

In a breakthrough with important implications for the future of immunotherapy for breast cancer, UC San Francisco scientists have found that blocking the activity of a single enzyme can prevent a common type of breast cancer from spreading to distant organs.
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Image: depiction of cells; Copyright: Yu Jung Shin

Cells: oxygen-starved tumor cells promoting cancer spread

08.11.2019

Using cells from human breast cancers and mouse breast cancer models, researchers at the Johns Hopkins Kimmel Cancer Center say they have significant new evidence that tumor cells exposed to low-oxygen conditions have an advantage when it comes to invading and surviving in the bloodstream.
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Illustration: RNA interaction surface of Fem-3-binding-factor 2 as predicted by NucleicNet; Copyright: 2019 KAUST

AI: revealing the nature of RNA-protein interactions

05.11.2019

A new computational tool developed by KAUST scientists uses artificial intelligence (AI) to infer the RNA-binding properties of proteins. The software, called NucleicNet, outperforms other algorithmic models of its kind and provides additional biological insights that could aid in drug design and development.
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Image: cancer cell gets treated with sound; Copyright: Tohoku University

Cancer treatment: attacking with sound

30.10.2019

Drugs can be safely delivered to cancerous lymph nodes via the lymphatic system and then released inside the nodes using sound waves. Tohoku University researchers tested the treatment on mice with metastatic breast cancer and published their findings in the journal Scientific Reports.
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Image: 3D-printed cell in a laboratory; Copyright: Allison Carter, Georgia Tech

3D-printing: finds cancer cells

29.10.2019

Finding a handful of cancer cells hiding among billions of blood cells in a patient sample can be like finding a needle in a haystack. In a new approach enabled by 3D-printed cell traps, researchers are removing the hay to expose the cancer cells.
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Image: ultrasound image of thyroid nodule; Copyright: Dr. Elizabeth Cottril, Thomas Jefferson University

Artificial intelligence: thyroid cancer on ultrasound

25.10.2019

Thyroid nodules are small lumps that form within the thyroid gland and are quite common in the general population, with a prevalence as high as 67 percent. The great majority of thyroid nodules are not cancerous and cause no symptoms. However, there are currently limited guidelines on what to do with a nodule when the risk of cancer is uncertain.
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Image: Brown cancer cells with other blue cell types in a schematic depiction; Copyright: Department of Nuclear Medicine and Tracer Kinetics, Osaka University Graduate School of Medicine

Radiotherapy: breaking the stroma barrier

22.10.2019

Pancreatic cancer is one of the leading causes of cancer related deaths worldwide. Patients with pancreatic cancer often receive chemotherapy or radiation therapy, which are not always effective and can have toxic side effects. The method may offer an effective treatment for pancreatic cancer with fewer side effects in surrounding organs.
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Image: a woman on a crosstrainer, next to her aphysiotherapist; Copyright: panthermedia.net / Kzenon

Sports medicine: for people with and beyond cancer

18.10.2019

It's well known that exercise is good for preventing and treating many forms of heart disease, but less commonly known are the benefits of physical activity for people living with and beyond cancer.
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Image: a man with an oxygen mask lying in bed; Copyright: panthermedia.net/ kasto

Cancer therapy: Oxygen in hyperbaric chamber provides relief

15.10.2019

Hyperbaric oxygen therapy (HBOT) can relieve self-reported symptoms and side-effects of radiotherapy against cancer in the pelvic region, a study shows. After 30–40 sessions in a hyperbaric chamber, many patients experienced reductions in bleeding, urinary incontinence, and pain alike.
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Image: a scanning electron image; Copyright: Melosh Lab

Immunotherapy: novel technique for cancer treatment

15.10.2019

Immunotherapy is a promising cancer treatment that uses genetically modified immune cells to fight cancer. It can be used as a primary treatment or in combination with other treatments such as radiation and chemotherapy to slow down or stop the growth of cancer cells and prevent them from spreading to other parts of the body.
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Image: a speaker in front of an audience; Copyright: panthermedia.net/ kasto

AI: machine learning and cancer care explored in Cleveland

14.10.2019

Artificial Intelligence (AI), machine learning and smart computing are all rapidly transforming the global health and medical landscape, including at Case Western Reserve University and among its health-care partners in Northeast Ohio and beyond.
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Image: close-up of a liver cancer stem-like cell; Copyright: Dr Toh Tan Boon, NUS N.1 Institute for Health

Cells: potential liver cancer treatment

10.10.2019

Liver cancer is the second leading cause of cancer-related deaths worldwide. The most common primary liver cancer in adults is known as hepatocellular carcinoma (HCC), and accounts for approximately 780.000 deaths every year. Even with advanced surgical treatments or transplantation, the 5-year survival rate for HCC patients remains poor due to frequent recurrence.
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Image: cells devouring tumor cells under a microscope; Copyright: Dr Fotini Vogiatzi

Immunotherapy: a promising antibody

07.10.2019

Acute lymphoblastic leukaemia (ALL) is the most common cancer in children. This form of blood cancer is caused by malignant abnormal precursor cells of certain white blood cells, and usually leads to a rapidly progressive reduction of bone marrow function, and thus impaired blood formation.
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Image: cancer cells; Copyright: The University of Texas at Dallas

Imaging: brighter way for capturing cancer during surgery

04.10.2019

University of Texas at Dallas researchers have demonstrated that imaging technology used to map the universe shows promise for more accurately and quickly identifying cancer cells in the operating room.
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Image: Illustration of a person in whose heart a beam and several particles are guided; Copyright: Mindy Takamiya

X-rays: safer, more effective cancer radiation therapy using nanoparticles

02.10.2019

An element called gadolinium delivered into cancer cells releases killer electrons when hit by specially tuned X-rays. The approach, published in the journal Scientific Reports, could pave the way towards a new cancer radiation therapy.
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Image: Illustrated DNA string; Copyright: Yen Strandqvist/Chalmers University of Technology

DNA: held together by hydrophobic forces

23.09.2019

Researchers at Chalmers University of Technology, Sweden, disprove the prevailing theory of how DNA binds itself. It is not, as is generally believed, hydrogen bonds which bind together the two sides of the DNA structure. Instead, water is the key. The discovery opens doors for new understanding in research in medicine and life sciences. The researchers' findings are presented in the journal PNAS.
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Image: nanomaterial structural image; Copyright: Santos Lab

Nanotechnology: nanomedicine for efficient chemotherapy

23.09.2019

Researchers at the University of Helsinki in collaboration with researchers from Åbo Akademi University,Finland and Huazhong University of Science and Technology,China have developed a new anti-cancer nanomedicine for targeted cancer chemotherapy. This new nano-tool provides a new approach to use cell-based nanomedicines for effcient cancer chemotherapy.
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Image: researcher works on the imaging device with a screw driver; Copyright: University of Waterloo

Imaging: revolutionizing cancer surgery

18.09.2019

Cancer treatment could be dramatically improved by an invention at the University of Waterloo to precisely locate the edges of tumors during surgery to remove them.
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Image: purple microscope image of squamous cell carcinoma of the lung and squamous cell carcinoma of the head and neck; Copyright: Jurmeister/Charité

Machine Learning: improving the diagnosis of head and neck cancers

16.09.2019

Researchers from Charité - Universitätsmedizin Berlin and the German Cancer Consortium have successfully solved a longstanding problem in the diagnosis of head and neck cancers. Working alongside colleagues from TU Berlin, the researchers used artificial intelligence to develop a new classification method which identifies the primary origins of cancerous tissue based on chemical DNA changes.
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Image: proton treatment room; Copyright: Penn Medicine

Imaging: proton therapy for children with cancer

13.09.2019

From improving outcomes in children with brain cancer to lowering the risk of damage to the brainstem in children with central nervous system tumors, a pair of new studies published today add to the growing body of research showing the potential benefits of proton therapy.
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Image: Laboratory situation - Prof. Popp shows a young man a small object in his hand; Copyright: Leibniz-IPHT/Sven Döring

Tumor excision: triple imaging for unique diagnostics

08.08.2019

After their tumor has been removed, some patients have to return to the hospital to undergo surgery again. That's because the tumor was not precisely identified and was subsequently not completely removed. That's both an ethical and financial dilemma. A new surgery-adjacent procedure is designed to rapidly and accurately detect tumors.
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Image: visitors at MEDICA; Copyright: Messe Düsseldorf

See, experience, learn: what's new at MEDICA 2018

02.11.2018

It's time: the world's largest medical trade fair opens its doors from 12 to 15 November. More than 5,000 international exhibitors will present their new innovative products and applications. Frums, conferences and special shows will feature exciting specialist lectures and discussions that will give you an insight into electromedicine, laboratory medicine, medical technology and diagnostics.
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Image: diagnosis of the lung; Copyright: panthermedia.net/Sergey Nivens

With modern imaging supplies: A look into the lung

01.10.2018

Thanks to various imaging supplies, it is possible to make the inside of the body accessible for diagnostics, research and treatment. The lung, one of the most important human organs for survival, is also examined in this way. In our Topic of the Month, we looked at how doctors are getting a closer look at the lung, how the procedures differ, and which ones will be available in the near future.
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Image: Small brown mole on the back of a hand; Copyright: panthermedia.net/Mario Hahn

Early detection: Tattoo signals cancer – and more

09.07.2018

People who are not ill and do not show any symptoms typically do not visit the doctor. And while most people know that preventive medical checkups for cancer, for example, are important, they still avoid them. They tend to be very hesitant because the doctor might detect a serious illness. In the future, a new type of implant could make it easier to go to a screening test.
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Personalized cancer medicine – Best possible treatment with TherapySelect

30.04.2018

Medicine is getting more and more personalized. This is particularly interesting for oncology, since a cancer is as individual as the respective patient. When choosing a therapy, both the characteristics of the tumor and the personal characteristics of the patient must be considered. To see exactly what this looks like, we visited the diagnostics company TherapySelect, based in Heidelberg.
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Image: DermaFC developed by Magnosco; Copyright: Magnosco

A startup makes melanin glow: skin cancer diagnostics with Magnosco

09.04.2018

When a skin lesion is suspected to exhibit malignant changes, it is usually promptly removed. However, not all cases require an excision of the affected tissue. The startup company Magnosco has developed a procedure that uses a laser to support the diagnosis and early detection of malignant melanoma.
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Image: Man with stethoscope and medical symbols; Copyright: panthermedia.net/everythingposs

Between austerity measures and growth pressure - Latin America's medical market

03.04.2018

A region whose states make up the world's third largest economy and which has few linguistic differences - Latin America is an attractive market for foreign companies at first glance. This also applies to the medical market. However, various factors are contributing to the fact that this market is growing only slowly in most countries.
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Image: A group of physicians is holding large colorful puzzle pieces in their hands and is putting them together; Copyright: panthermedia.net/Andriy Popov

Personalized medicine: a paradigm shift is gaining momentum

01.03.2018

Personalized medicine does not follow a "one-size-fits-all" treatment approach but emphasizes a "tailor-made" paradigm, meaning a treatment is customized to each individual person's case. For patients, this increases the chances of treatment success and means fewer side effects. While the approach originates in the field of oncology, it is now also increasingly applied to other disease patterns.
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Image: Three men in suits and a woman in a laboratory coat are standing in a laboratory; Copyright: Ministry of Economy of Mecklenburg-Hither Pomerania/Norbert Fellechner

On the trail of cancer: personalized cancer vaccine

01.03.2018

Conventional cancer treatment selection typically depends on the location of the tumor. However, this approach ignores the distinct gene mutations in the tumor of the individual patient. New cancer research approaches increasingly emphasize the concept of personalized therapy.
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Image: yellow tape measure with capsules in front of it; Copyright: panthermedia.net/Jiri Hera

Personalized cancer medicine: customized treatment

01.03.2018

Everyone is different. This statement also applies to our health. Cancer, in particular, can look and progress differently depending on the individual person. That’s why every patient ideally also needs a customized treatment that is tailored to their individual needs. But how feasible is this idea?
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Image: a container with the nutrient medium for cancer cells; Copyright: Dr. Markus Wehland

Cells in space – extraterrestrial approaches in cancer research

22.02.2018

Here on Earth, all experiments are bound by gravitation. Yet, freed from gravity's grip, tumor cells, for example, behave in an entirely different way. As part of the "Thyroid Cancer Cells in Space" project by the University of Magdeburg, smartphone-sized containers carrying poorly differentiated thyroid cancer cells are sent into space.
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Image: Preview picture of video

MEDICA 2017: Cutting-edge, look into the future

13.11.2017

For exhibitors and visitors, MEDICA 2017 does not start until Monday. However, the trade press already gets a preview of some selected product highlights on the Sunday before the trade fair. We were there with the camera and met with some exhibitors. They gave us the opportunity to present cutting-edge products and to take a look at the medical technology of the future.
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Image: Vials in a rack; Copyright: Messe Düsseldorf

MEDICA 2017: all about laboratory medicine at the MEDICA LABMED FORUM

02.10.2017

If you are interested in laboratory medicine and come to the MEDICA 2017, you will quickly notice that Exhibition Halls 1 and 2 were demolished. A new state-of-the art hall is meant to take their place. Until then, exhibitors from the field of laboratory medicine will be showcased at their temporary new location in the lightweight hall structures 3a and 18 on the fairgrounds.
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Image: Colored sonographic image of the human heart from Doppler ultrasonography; Copyright: panthermedia.net/Belish

Imaging techniques: ultrasound, MRI, CT, catheters and other procedures to keep a healthy heart

01.09.2017

Many people are affected by heart disease today because - among other reasons- our modern unhealthy lifestyle is taking a toll on our hearts. A reliable diagnosis and treatment are crucial for patients with heart disease since all other organs depend on the pumping of our vital organ. Modern imaging techniques are a key to understanding the heart.
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Image: interferometric detection of scattered light, iSCAT; Copyright: MPL

Interface between Physics and Medicine: new interdisciplinary center

22.08.2017

Physics has always supported medical science, especially when it comes to practical implementation. Now physicists and health professionals join in collaborative research at an interdisciplinary Center in Erlangen and incorporate fundamental principles of theoretical physics in their studies of diseases.
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Image: A large medical device with a treatment couch and four movable boxes; Copyright: panthermedia.net/Thomas Hecker

Cancer: refined treatment with proton minibeams

10.07.2017

Radiation therapies are an essential component of today’s oncology because they enable the treatment of localized tumors. Yet they have one major drawback: radiation damages not just tumor cells but also healthy tissue. One solution to solve this problem could be proton minibeam therapy, which uses finely focused beams.
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Image: A flat device with a touch screen; Copyright: biolitec AG

Surgical lasers: the quest to be compact, mobile, and user-friendly

03.07.2017

Not all lasers are the same – especially in the surgical field, it all depends on what’s inside: the different operational wavelengths of laser light also affect human tissue in different ways. This is why a single laser for a variety of applications drastically simplifies the job of physicians.
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Image: A dermatology laser is used to remove a mole; Copyright: panthermedia.net/Michael Krause

Laser surgery: usability, flexibility, treatment quality

03.07.2017

The scalpel is considered the classic surgical instrument and as such, has remained unchanged for quite some time. However, today’s technology opens up a world of new possibilities for cutting tissue. Next to high-frequency electrosurgical scalpels that work with electric power, surgeons also use a variety of different lasers. They promise great usability and better treatment.
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Image: Preview picture of video

Photochemical internalization – A new hope against bile duct cancer?

03.07.2017

Advanced bile duct tumors cannot always be removed surgically. Then, patients receive chemotherapy and a stent that corrects the narrowing of the bile duct that is caused by the tumor. Another, local therapy option is tested at the University Hospital Frankfurt: laser light is used to transport drugs into the tumor during photochemical internalization.
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Image: A women with a bald head and a headscarf, smiling, sitting on a sofa talking ot another woman; Copyright:Katharina Bia asiewic

Irreversible Electroporation – Last hope for liver cancer patients

24.04.2017

Liver cancer is the fifth most common malignant tumor in the world. The tumor can be removed through surgery or by utilizing thermal ablation techniques. If a treatment with conservative methods is no longer possible, there is an alternative: irreversible electroporation (IRE). The effectiveness of this method was now confirmed by a clinical study.
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Image: A young girl is lying in the hospital bed, behind her a nurse is adjusting a monitor; Copyright: panthermedia.net / Monkeybusiness Images

Working with children with cancer – More than just a job

02.01.2017

Our topic title "pediatric (children’s) oncology" evoked strong emotional reactions from several mothers and fathers of our staff. "This hits too close to home for me, I couldn’t write about it", or "How do people manage to deal with this?". And we are only on the sidelines; physicians, caregivers and nurses at the hospital, hospice or families at home are the ones that have the real tough job.
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Image: Three physicians during a meeting; Copyright: KiTZ/Philipp Benjamin

Children's Tumor Center: consolidated treatment under one roof

02.01.2017

Treatments for children need to be different from treatment for adults – this also applies in oncology. Having said that, children do not just need new and different treatment concepts that still necessitate research. They also require the support from their families, who need to be nearby during treatment.
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