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iLexx
The architecture of shattered genomes
27/01/2023
Hunting for disease clues in the dark matter of our DNA. Scientists have reconstructed the chromosomes of patients with an extremely high number of aberrations in their genome that could alter the expression of nearby genes and potentially cause disease. Their results were published in Nature Communications in October 2022.
iLexx
Bacterial electricity: Membrane potential influences antibiotic tolerance
27/01/2023
The electrical potential across the bacterial cell envelope indicates when bacteria no longer operate as individual cells but as a collective. Researchers at the University of Cologne's Institute for Biological Physics have discovered this connection between the electrical properties and the lifestyle of bacteria.
Beachbumledford
Controlled manufacture, storage and freezing of artificial retinal cells
25/01/2023
Fraunhofer researchers have now developed a new method for the production and clinical application of stem-cell-based retinal implants, which could contribute towards the successful treatment of AMD.
dolgachov
Type 2 diabetes: Machine learning can predict poor glycemic control from patient information systems
13/01/2023
The risk for poor glycemic control in patients with type 2 diabetes can be predicted with confidence by using machine learning methods, a new study from Finland finds.
Aalto University
Gaining unprecedented view of small molecules by machine learning
06/01/2023
A new tool to identify small molecules offers benefits for diagnostics, drug discovery and fundamental research. A new machine learning model will help scientists identify small molecules, with applications in medicine, drug discovery and environmental chemistry.
Max-Planck-Institut für Polymerforschung
How optical microscopes allow detailed investigations of nanoparticles
06/01/2023
In their project "Supercol"- funded by the European Union - scientists want to achieve the investigation of nanoparticles with light.
University of Freiburg
New findings on neuronal activities in the sensorimotor cortex
19/12/2022
An interdisciplinary research team at the University of Freiburg has found important clues about the functioning of the sensorimotor cortex. The new findings on neuronal activities in this brain area could be helpful for the further development and use of so-called neuroprostheses.
Fraunhofer ITEM
Designer immune cells for drug discovery, potency and safety testing
14/12/2022
Fraunhofer researchers have succeeded in scaling the production of customized immune cells from laboratory up to industrial level.
Völkner et al., Nat. Comm., 2022
Macular degeneration: new potential mechanism for vision loss discovered
09/12/2022
Thanks to laboratory produced human mini-retinas, researchers were able to observe complex changes in the retina as they occur in macular degeneration. This enabled them to discover the so-called cell extrusion as a potential mechanism for neurodegenerative diseases.
Junjie Yao, Duke University
Small glowing protein allows researchers to peer deeper into living tissues
08/12/2022
Biomedical and genetic engineers at Duke University and the Albert Einstein College of Medicine have designed a small fluorescent protein that emits and absorbs light that penetrates deep into biological tissue. Tailored to wavelengths in the near-infrared (NIR) spectrum, this protein can help researchers capture deeper, cleaner, more precise biomedical images.
mstandret
Why are overweight people more susceptible to illness?
07/12/2022
If you gain weight, the fat cells in the body get bigger. So in the extremely obese, those fat cells are greatly enlarged. Now, researchers from the Technical University of Munich (TUM) were able to show how enlarged fat cells can cause metabolic diseases. They also developed non-invasive examination methods to determine the size of human fat cells.
Paul Schütz
How lymph nodes are supplied with blood
07/12/2022
3D images have been obtained that show the vascular system of the nodes with previously unattained resolution.
IfADo / Anne Gregory
Working memory: Preparing for the unknown
02/12/2022
In a recent study, a group of researchers at Leibniz Research Centre for Working Environment and Human Factors at TU Dortmund (IfADo) shed light on the prerequisites for the initiation of motor preparation processes in working memory.
Keisuke Ishihara
Measuring organ development
28/11/2022
Researchers from Dresden and Vienna reveal link between connectivity of three-dimensional structures in tissues and the emergence of their architecture to help scientists engineer self-organising tissues that mimic human organs.
Polygraph Design
How genes and small molecules influence personal disease risk
25/11/2022
In an international collaboration with partners from Cambridge (UK), scientists from the Berlin Institute of Health at the Charité (BIH) have now discovered more than 300 regions in the genome that contribute to this individual chemical fingerprint. They have now published their results in Nature Medicine.
FoToArtist_1
Warmer brain-irrigation fluid in surgery more efficacious
25/11/2022
A simple method can halve the number of repeat operations to remedy bleeding under the cranium, a study at the University of Gothenburg shows. The method is based on replacing irrigation fluid at room temperature with fluid at body temperature.
Tel Aviv University
Ultrasound and nanobubbles allow cancerous tumors to be destroyed
23/11/2022
A new technology developed at Tel Aviv University makes it possible to destroy cancerous tumors in a targeted manner, via a combination of ultrasound and the injection of nanobubbles into the bloodstream.
University of Oslo
Resistances: these bacteria hide and then take charge
23/11/2022
A doctor discovers bacteria in a sample that is causing a case of pneumonia and prescribes antibiotics. But at the same time, there is another, nastier variant of bacteria lurking in the patient’s body that is very glad to have got rid of its competitor.
Nikita_Karchevskyi
Tumors: forecasting the risks of brain surgery
22/11/2022
Can surgeons quantify the risk of aphasia when removing a brain tumor? To find out, researchers at Klinikum rechts der Isar of the Technical University of Munich (TUM) are analyzing the brain as a network. In a current study with 60 patients, they already achieved an accuracy rate with three quarters of their predictions.
Nikita_Karchevskyi
Quantum technology for cancer imaging
21/11/2022
Tracing the metabolism of tumor cells using magnetic resonance imaging (MRI) has not been feasible in routine clinical settings hitherto. Now, an interdisciplinary research team including the Technical University of Munich (TUM) is working to advance the development of a quantum-based hyperpolarizer so that it can be deployed in clinical applications.
Iakobchuk
MEDICA 2022: Simplifying analysis and visualization of medical image data
15/11/2022
A team of researchers from Kaiserslautern and Leipzig is working on a system that automatically analyses and visualises medical data, including their uncertainties.
Fraunhofer IBMT/Markus Michel
MEDICA 2022: Biological laboratory to go
10/11/2022
Researchers from the Fraunhofer Institute for Biomedical Engineering IBMT have developed the “BioSensoLab“, a mobile biological laboratory with which they can demonstrate new developments to customers and test them together – on site at their companies.
BarcelonaTech (UPC)
Maria Pau Ginebra awarded Advanced Grant by ERC
01/11/2022
The European Research Council (ERC) has awarded UPC researcher Maria Pau Ginebra an Advanced Grant to study the mechanisms of biomaterial and bacteria interaction and to develop surfaces that can fight infections and promote bone regeneration.
beta web GmbH/Melanie Prüser
Single-use tests: sensitivity and easy use combined for diagnostics
12/12/2019
Diagnostic testing usually takes some time and a sterile environment to get the results. To cut down on the costs and effort spend on these tasks there are different diagnostic tests. One of them are single-use tests offered by SensDx S.A. The technology behind them not only makes the process faster and easier, but provides the opportunity to expand into home use in the future as well.
AAL Living Lab: research, education and raising awareness
02/12/2019
Smart home systems are a perfect example of how technology can make our daily lives easier. The fact that they can use a tablet to adjust lighting and blinds in every room benefits older adults in more ways than one. These types of technical systems are a part of Ambient Assisted Living (AAL) and create a safe living environment for older persons.
Ambient Assisted Living: sensors for seniors
02/12/2019
Our ageing society is confronted with fewer and fewer workers. One of the many consequences is a shortage of skilled nursing staff. Ambient Assisted Living should solve this problem. By equipping the living environment of elderly people or people in need of care with (technical) assistance systems, they are to be given more self-determination and security. The nursing staff also benefits.
Wearables: more freedom with the smart care patch
02/12/2019
Too many people in need of care and not enough health care professionals – we all know the problem. For years, research is underway to find digital solutions for AAL to support the growing number of older & sick adults. These new technologies aim to both alleviate caregiver burden and enhance everyday life of people in need of care with a minimum level of constraint whilst promoting independence.
Smart care: safety and support thanks to AAL
02/12/2019
Average life expectancy keeps increasing, while birth rates are declining – at least when it comes to most industrial nations. The coming decades will see a decreasing number of gainfully employed people versus more and more senior citizens and people in need of care. It's a trend that already pushes healthcare to the brink. That's why we desperately need new concepts. One of them is AAL.
panthermedia.net/olanstock
Cardiac diagnostics – prompt and personalized
08/11/2019
If physicians suspect an acute myocardial infarction, they first order an ECG. This test is very established and allows cardiologists to quickly diagnose acute heart attacks – though the test does not detect less common heart attack symptoms. So far, those patients had to wait up to twelve hours before a heart attack could be accurately diagnosed or ruled out. But things are about the change.
Medicine at the pulse of time: Innovations and trends at MEDICA 2019
04/11/2019
Soon, the world's largest trade fair for medical technology will open its doors again: More than 5.000 exhibitors will present their newest products and ideas at MEDICA from 18 to 21 November. You will not only meet well-known companies here, but also lots of young start-ups. Or, you can visit the MEDICA forums and conferences to experience a rich program of lectures and discussions.
Fraunhofer ISS
AI software: "iSTIX opens your world to the possibilities of digital pathology"
08/10/2019
The healthcare market offers a multitude of microscopes that make cells visible to the human eye. The same applies to AI-based software for image analysis. After taking the microscopic images, scientist are faced with large volumes of scans with usually low resolution. Yet when all aspects merge together, they open up a the world of digital pathology.
MEDICA START-UP PARK 2019: Experience tomorrow's innovations today
01/10/2019
The medical market is booming - medical ideas and visions for the future are more in demand than ever. Especially at MEDICA START-UP PARK 2019 young founders want to present their product innovations. Develop business contacts, meet investors and experience an international environment in just one place. Discover in our Topic of the Month what makes MEDICA START-UP PARK unique.
MEDICA START-UP PARK: "For those, who want to experience the startup-spirit"
01/10/2019
When the halls of MEDICA are open to the world to showcase medical innovations, one joint exhibition booth is guaranteed to attract special attention - the MEDICA START-UP PARK. The startups that present their advances in this setting are interesting to visitors and investors, yet long-time exhibitors and big businesses can also benefit from building relationships with these young companies.
Telemedicine: easy breathing with AI for respiratory tract
01/10/2019
Pneumonia, COPD or cystic fibrosis – people with such lung diseases have to consult their doctor regularly. Little children have to undergo certain measurements by the doctor, too. In order to save people`s need to visit a doctor, telemedicine offers many ways to do examinations at home.
panthermedia.net/kasto
Cardiac Tissue Engineering: a heart out of the Petri dish
23/09/2019
For patients waiting for donor organs, every day can mean the difference between life and death. Making things even more complicated is the fact that not every organ is a compatible match with the patient. It would mean enormous progress if we could grow organs from the patient's own cells in the lab. That's why patients with heart disease place big hope in tissue engineering.
AI in radiology: reliable partner for diagnosing CT images
02/09/2019
More patients, more examinations, more CT images – in radiology there is too much work for too few physicians. CT scans are evaluated in the shortest possible time, which leads to anomalies being overlooked. Artificial intelligence, on the other hand, works with constant speed and performance, which is why radiological routine increasingly relies on its support.
Man vs. machine – the benefits of AI in imaging
02/09/2019
Radiology is a field that produces large volumes of data, which can no longer be managed without the help of intelligent systems. This is especially true when it comes to the interpretation of medical images. While this takes physicians years of training and experience, several hours of work and the highest level of concentration, AI only requires a few seconds to accomplish the same task.
AI in imaging: how machines manage our Big Data
02/09/2019
In modern medicine, especially in the field of imaging, huge amounts of data are produced – so much that radiologists can hardly keep up with diagnosing the images. Artificial Intelligence could be the solution to this problem. But how exactly can it help in this task? How can man and machine work together? And what else will be possible in the future with the support of intelligent systems?
German Medical Award
German Medical Award 2019 celebrates the future of (patient) care
22/08/2019
The German Medical Award will take place on November 18, 2019, as part of the MEDICA trade fair in Düsseldorf. The ceremony emphasizes the commitment to excellence in cutting-edge care for patients. Doctors, clinical centers and companies in the medical and healthcare industry can demonstrate their achievements in medicine and management in hopes of receiving the coveted award.
Leibniz-IPHT/Sven Döring
Tumor excision: triple imaging for unique diagnostics
08/08/2019
After their tumor has been removed, some patients have to return to the hospital to undergo surgery again. That's because the tumor was not precisely identified and was subsequently not completely removed. That's both an ethical and financial dilemma. A new surgery-adjacent procedure is designed to rapidly and accurately detect tumors.
Antibiotic resistance: technical tricks against pathogens
01/08/2019
An untreatable infection is a nightmare for physicians and potentially life-threatening to the patient. Unfortunately, more and more pathogens emerge that are resistant to drugs, especially antibiotics. We need to use our drugs smartly and come up with technical solutions as well to prevent our weapons from blunting in the future.
SilverSky LifeSciences GmbH
Striking new paths in medicine - Diagnostics Partnering Conference 2019
08/07/2019
On November 18th, 2019, parallel to the first day of MEDICA, the world forum for medicine, the Diagnostics Partnering Conference (DxPx Conference) will take place in Düsseldorf, bringing together stakeholders in the diagnostics and research tool industry. The DxPx Conference focuses on discovering technologies, finding financing and investment opportunities and forming collaborative partnerships.
Performance diagnostics: success in sports – testing the limits of performance
01/07/2019
Stationary or mobile - competitive athletes rely on regular health assessments. They must deliver peak performance and be physically fit during competitions. But when do they reach their physical limits? Are there any devices that provide information, no matter where the test subject is located?
Sports medicine - performance values in best health
01/07/2019
Those who integrate physical activities into their own lifestyle live healthier and more balanced. But where are the physical limits? Can health status measurements also be carried out on the road? Discover more about how sports medical examinations contribute to maintain performance and minimize health risks in our Topic of the Month.
Sports medicine – keep moving to stay healthy
01/07/2019
Physical activity plays a big role in today's society. Whether you are an amateur or professional athlete – incorporating exercise into your life positively impacts your mental and physical health. Ideally, sport should be fun, pressure-free and not overburden you. But can you measure individual performance and align it with sports?
Capsix Robotics, Lyon
Healthy Living thanks to robotics – KUKA Innovation Award 2019
24/06/2019
Improving technology transfer from research to industry and driving robotics development - that's the idea behind the KUKA Innovation Award. This year’s topic is "Healthy Living". Applicants from around the world were tasked with creating a robot application for healthcare settings. Now, the finalists, who will showcase their innovations at the MEDICA 2019 trade fair have been selected.
Robotics – rehab with motors and sensors
03/06/2019
They work with power, precision and tirelessly. This makes robots an ideal instrument for rehabilitation. In gait or motor training, movement sequences must be repeated thousands of times so that they can be learnt anew. What tires the patient and costs the therapist's time can easily be managed by robot-assisted systems. Learn more about the possibilities of robotics in rehabilitation.
Of exoskeletons and service robots – the future of rehabilitation
03/06/2019
For most people, enjoying a good quality of life means having the ability to move freely, safely and independently. Intensive and costly rehabilitation is needed if this is no longer an option after a stroke for example. We are introducing some projects that deliver innovative robotic solutions.
Walking is an issue of mind over matter – how robots assist rehabilitation
03/06/2019
Humans are living longer than ever but still want to continue to live independently as they age. Meanwhile, our motor and cognitive abilities decline as we age, sometimes as the effects of a stroke. The number of people in need of long-term care is growing at breakneck speed. At the same time, fewer and fewer young people choose stressful careers as caregivers.
panthermedia.net / Lev Dolgachov
mHealth: Atrial fibrillation detection – App supports heart health
08/05/2019
Atrial fibrillation is the most common type of persistent cardiac arrhythmia (irregular heart rhythm). Researchers estimate that 1.8 million Germans are presently affected by this disease. The condition is difficult to diagnose, frequently goes undetected and may result in a stroke. A new smartwatch medical app is designed to help patients detect atrial fibrillation before it’s too late.
Functional imaging: what makes the brain tick?
01/04/2019
Our brain is the command center of our body. This is where all information and impressions are collected and converted into responses and movements. Modern imaging techniques offer physicians and researchers unique insights into the actions of the human central nervous system. The functional imaging technique allows them to watch our brain in action.
Functional imaging: a look at the command center
01/04/2019
All information from our body and the environment converges in our brain and is transformed into reactions in milliseconds. It is essential for medicine and research to know what our switching centre looks like. Functional methods are used to observe it more closely during work.
React early, breathe free – comprehensive COPD management
01/03/2019
COPD is considered the third most common cause of death worldwide and mainly affects smokers. It is not curable, but with the right combination of early diagnosis, therapy and self-management, a significant part of the quality of life can be regained. The comprehensive care is supported by various devices and technical tools. Learn more about the all-round care of COPD in our Topic of the Month.
Fraunhofer ITEM/Till Holland
Gentle medication for the little ones – with every breath
22/02/2019
According to the WHO, ten percent of babies worldwide are born prematurely. Since most organs of these tiny babies have not fully developed yet, it can quickly lead to complications and disorders and most notably affect the lungs of the premature infants. What's more, infections require gentle treatment, as the preemies themselves are fragile and susceptible – making this a challenging situation.
Organ-on-a-chip – Organs in miniature format
01/02/2019
In vitro processes and animal tests are used to develop new medications and novel therapeutic approaches. However, animal testing raises important ethical concerns. Organ-on-a-chip models promise to be a feasible alternative. In a system the size of a smartphone, organs are connected using artificial circulation.
Organ-on-a-chip systems: limited validity?
01/02/2019
Organ-on-a-chip systems are technically a great enhancement of medical research because they facilitate testing of active ingredients on cell cultures in the chambers of a plastic chip. This replaces animal testing and improves patient safety. That being said, they are not a true-to-life replication of the human body and can only simulate a few functions and activities.
Multi-Organ Chips – The Patients of Tomorrow?
01/02/2019
The liver, nervous tissue or the intestines: all are important human organs that have in the past been tested for their function and compatibility using animal or in vitro test methods. In recent years, TissUse GmbH, a spin-off of the Technical University of Berlin (TU Berlin), has launched multi-organ chip platforms. But that’s not all.
Organ-on-a-chip - the mini organs of the future?
01/02/2019
So far in vitro methods and animal experiments have been used to determine the causes of diseases, research therapeutic approaches and predict the effect of drugs. Organ-on-a-chip models now offer a more accurate and ethically justifiable alternative. Find out more about the models, their advantages and future developments in our Topic of the Month.
panthermedia.net/Andrey Popov
AI ensures dynamic sitting
22/01/2019
Whether in the office, at school or behind the wheel: we spend a lot of time sitting and often stay in the same position for too long. The possible side effects are stiffness, back problems and pain. The SensA-Chair smart seating solution combats decreased mobility and ensures dynamic sitting.
Marc Eisele, Universitätsklinikum Dresden
Better living thanks to telemedicine – "TelePark"- project targets patients with Parkinson’s disease
08/01/2019
Parkinson's disease is a progressive nervous system disorder that primarily affects movement of patients and makes their everyday lives very challenging. It also makes regular doctor appointments and treatment sessions necessary. "TelePark" - a project that collects different movement-related parameters using sensors and apps is designed to improve the quality of life for Parkinson’s patients.
A digital look inside the human eye – when algorithms diagnose Diabetes
02/01/2019
Diabetes mellitus or simply diabetes has become very common and is often described as a lifestyle disease. More and more people are suffering from this chronic metabolic disorder. Next to established diagnostic procedures, digital retinal screening has shown to be successful - a promising technique that will also play an important role in the diagnosis of other diseases in the future.
Blood glucose monitoring of tomorrow - modern diabetes therapies
02/01/2019
There are 425 million people with diabetes in the world. Heart problems, kidney failure or blindness - these can all be consequences of the metabolic disease. Diabetes patients now have the possibility of being treated digitally.