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Zebrafish and AI replace some mouse experiments in cancer research
11/01/2022
Researchers at Uppsala University have used AI to develop a new method to study brain cancer. The method is based on transplanting tumour cells from patients to fish embryos, followed by observation with AI. The method, which is described in the scientific journal Neuro-Oncology, can partly replace current mouse models for studying tumour growth and treatment.
Robotics in Intensive Care Units: "Stand Patients up on Their Feet and Let Them Walk"
04/01/2022
Robotics have made their way into many areas in healthcare. So far, intensive care units had not utilized robotic systems. Now there is an application that facilitates ICU care tasks.
Grant for clinical trial of exoskeleton technology
03/01/2022
Mechanical engineer and inventor Zach Lerner, assistant professor in Northern Arizona University's Department of Mechanical Engineering, has been awarded $2.1 million by the National Institutes of Health's Eunice Kennedy Shriver National Institute of Child Health & Human Development.
Exercise rehabilitation as tool for managing symptoms of multiple sclerosis
03/01/2022
Citing recent evidence, experts in rehabilitation research advocate for integrating exercise into the care plans of persons with multiple sclerosis. The central role of the neurologist in clinical care offers an opportunity for this provider to promote exercise as fundamental for managing the physical and cognitive symptoms of MS.
Wearable biosensors can help people with complex health conditions
20/12/2021
Remote monitoring of health-related behaviour with wearable sensor technology is feasible for people with complex health conditions, shows a recent University of Waterloo study.
Mayo Clinic researchers use AI and biomarkers to personalize rheumatoid arthritis treatment
20/12/2021
Treatment options for rheumatoid arthritis have often relied on trial and error. Now Mayo Clinic researchers are exploring the use of artificial intelligence (AI) and pharmacogenomics to predict how patients will respond to treatments, and to personalize care. Findings were published in Arthritis Care & Research.
Health Equity: How digitalization can promote global health access
17/12/2021
Scissors symbolize a gap and problems in today’s society. One of them is global health inequalities: While developed countries tend to have a surplus of doctors and medical professionals, people with medical problems in low-income countries must often travel hundreds of miles before they find access to health services.
Advances in sleep disorder diagnostics
15/12/2021
Sleep disorders and insufficient sleep are major global problems contributing to,for example, increased health care costs and sick leaves, and reduced quality of life. According to recent estimates, sleep apnoea alone affects approximately 1 billion people worldwide, and up to half of the world's population suffers from insomnia at some point in their lives.
New AI system provides consistent endoscopic evaluation
14/12/2021
Researchers at Tokyo Medical and Dental University (TMDU) develop an artificial intelligence system for detecting and characterizing disease conditions using real-time clinical video imaging, reducing the need for expensive and invasive biopsies.
Novel computer simulation method can accelerate COVID-19 drug discovery
13/12/2021
A study by researchers affiliated with institutions in Brazil, Germany and Finland proposes a new standard for computer simulation that promises to accelerate the search for novel bioactive compounds against the virus that causes COVID-19.
AI-powered computer model predicts disease progression during aging
08/12/2021
Using artificial intelligence, a team of University at Buffalo researchers has developed a novel system that models the progression of chronic diseases as patients age.
AI: A new tool in the fight against rectal cancer
06/12/2021
Building on its successes in applying artificial intelligence (AI) to medical imaging to enhance treatment of other diseases, a Case Western Reserve University-led team next will test its approach with rectal cancer patients. Specifically, the researchers hope to provide reliable guidance regarding whether patients need to have surgery as part of their treatment.
Battling myocardial infarction with drug-coated balloon catheters
02/12/2021
A drug-coated balloon catheter inserted in minimally invasive cardiac surgery is increasingly serving as a replacement for the risky stent treatment. In current practice, the balloons are often coated manually. A new device is intended to automate this time-consuming procedure. Along with partners, a team from the Fraunhofer IPK is developing a prototype of such a device.
New algorithm could save lives: Predicts COVID-related intensive care unit resource use
01/12/2021
A new algorithm can predict how many patients will need intensive COVID-related healthcare. This is valuable knowledge when it comes to prioritising caregivers and ventilators in individual hospitals. The innovation could save lives, according to the UCPH.
Hypoxia imaging and combination therapy aid immunotherapy treatment of solid tumors
29/10/2021
Immunotherapy using checkpoint inhibitors can work well to treat cancer, but only a minority of patients respond to therapy. Researchers at the University of Alabama at Birmingham have now shown — in preclinical experiments — how to identify non-responding tumors and improve their response to immunotherapy, as shown by limited tumor growth and extended survival.
Worth a thousand words: Automated diagnosis of COVID-19 from Chest CTs
25/10/2021
Chest CT scans have emerged as a quick and effective way to diagnose the disease, but they require radiologist expertise to interpret, and sometimes the scans look similar to other kinds of lung infections, like bacterial pneumonia.
Removing kidney stones thoroughly and without residue
13/07/2021
Kidney stones are a widespread disease. In order to be able to reliably remove even the smallest remnants of them, Purenum GmbH, a spin-off of Fraunhofer Institute for Manufacturing Technology and Advanced Materials IFAM, developed a gel that encloses small fragments and can then be removed without leaving any residue. This year, the product mediNiK was certified and is thus ready for the market.
Point-of-care ultrasound helps in emergency diagnosis
01/06/2021
Medical emergencies require quick action and prompt decisions: Point-of-care ultrasound (POCUS) is a valuable diagnostic tool available to the emergency physician. Rather than relying on his/her gut feeling, the device answers specific clinical questions that narrow differentials. The question is, in which settings does POCUS deliver the biggest benefits?
Making biohybrid lungs implantable
25/05/2021
Diseases can affect the lungs in different ways that can be challenging. If the lungs are badly damaged and artificial ventilation (also called artificial respiration) is no longer effective, an ECMO machine comes into play. Right now, artificial lungs reside outside the body and cannot be implanted.
Digital healthcare: Treating patients at home
03/05/2021
Digital health apps (DiGA) are increasingly becoming part of patients' everyday lives. Since the "apps on prescription" are thoroughly tested by the BfArM before approval, they are currently only tailored to individual diseases. In this Topic of the Month, we take a look at the place DiGAs already occupy in healthcare today and how they will continue to develop in the future.
Surgery in 3D: Virtual Reality in the OR
01/04/2021
Surgeons do not only have to gather theoretical knowledge and practice to perform successful interventions. They also need a good visual thinking and have to know the anatomical characteristics of each individual patient. Some of these tasks will become easier when Virtual and Mixed Reality bring three-dimensional, digital models into their profession.
Autonomous medical technology: independently in the body
01/02/2021
Therapies need to be carried out with high reliability by trained personal. This will not change in the future. But maybe we will be able to let systems in the patient’s body do some of the work. Some approaches are already aiming to make implants more independent so they will be able to flexibly react to changes. Read more in our Topic of the Month!
Israeli medical devices showcase digital innovations at MEDICA
24/08/2020
For the annual MEDICA trade fair, companies from all over the world assemble in Düsseldorf. The Israel Export Institute has been a part of it for the last couple of years. They present medical devices and digital innovations from different Israeli companies at their joint booth.
VitalSky: how an artificial sky improves ICU patient recovery
03/08/2020
Delirium occurs in 30 to 80 percent of patients in intensive care units. This cerebral impairment not only causes mental confusion and emotional disruption but also drastically increases the mortality risk of patients. A controlled circadian rhythm and sleep/wake cycle is the prerequisite for delirium prevention. This is where the new VitalMinds concept from Philips comes in.
Big Data: early warning system for the ICU
03/08/2020
Patient monitoring systems in the ICU sound up to 700 alarms on average per patient per day, which boils down to one alarm every two minutes. An excessive number of them are false alarms. This generates vast amounts of data, which can make it difficult for doctors and nurses to identify the most critical alarms to manage. It also has a negative effect on the treatment of intensive care patients.
Stroke care: When every minute counts
02/06/2020
Stroke can affect anyone – older as well as younger people. The minutes after the stroke determine whether disability or death is the result. Only if acute care, inpatient treatment and rehabilitation are carried out in a targeted and effective manner, the chances are greater that only minor damage remains or that impairments even recede.
Mobile stroke units: improved outcomes for ischemic stroke
02/06/2020
If someone is having a stroke, you call an ambulance. But getting to the hospital can be time-consuming. To prevent long-term disabilities and death, patients need to be treated as quickly as possible. According to a recent study by the Charité – Universitätsmedizin Berlin, mobile stroke units play a key role in this setting.
Robotic-Assisted Surgery with the daVinci-System
04/05/2020
Robotic surgical systems are often used to perform minimally invasive procedures. The daVinci surgical system is still one of the market leaders and is especially well suited to perform prostatectomies, a surgical option for prostate cancer.
Robotics in the OR: Relieving the surgeon
04/05/2020
In the operating room, minimally invasive procedures are increasingly used. Robot-assisted systems are a great help for the surgeon. They support the surgeon and are extremely precise. Through innovative research approaches, robotic systems are constantly evolving.
Regenerative medicine: helps the body healing
03/02/2020
Severe wounds heal slowly and leave scars. This is why we have been using regenerative therapies for some time now to accelerate and improve healing. They also help to avoid permanent damage. Still, complex applications like replacing organs or limbs will rather remain vision than become reality for a long time.
Endoprostheses: regaining independence and mobility
01/01/2020
Joints can suddenly or gradually deteriorate and lose their natural strength, whether it’s due to accidents, diseases or simple wear and tear. In some of these cases, implants of artificial joints – endoprostheses - can help. As a joint replacement, they are designed to stay in the body for as long as needed and as such improve the patient’s quality of life and mobility.
Endoprosthetic surgery: modern and traditional approaches
01/01/2020
Surgery is required if you need an artificial joint. Patients and doctors must select the type of surgery that’s best suited and choose between robot-assisted, traditional or minimally invasive surgical approaches. Post-operative risks should be kept to a minimum, while benefits should outweigh any possible complications.
Cardiac diagnostics – prompt and personalized
08/11/2019
If physicians suspect an acute myocardial infarction, they first order an ECG. This test is very established and allows cardiologists to quickly diagnose acute heart attacks – though the test does not detect less common heart attack symptoms. So far, those patients had to wait up to twelve hours before a heart attack could be accurately diagnosed or ruled out. But things are about the change.
Cardiac Tissue Engineering: a heart out of the Petri dish
23/09/2019
For patients waiting for donor organs, every day can mean the difference between life and death. Making things even more complicated is the fact that not every organ is a compatible match with the patient. It would mean enormous progress if we could grow organs from the patient's own cells in the lab. That's why patients with heart disease place big hope in tissue engineering.
German Medical Award 2019 celebrates the future of (patient) care
22/08/2019
The German Medical Award will take place on November 18, 2019, as part of the MEDICA trade fair in Düsseldorf. The ceremony emphasizes the commitment to excellence in cutting-edge care for patients. Doctors, clinical centers and companies in the medical and healthcare industry can demonstrate their achievements in medicine and management in hopes of receiving the coveted award.
Striking new paths in medicine - Diagnostics Partnering Conference 2019
08/07/2019
On November 18th, 2019, parallel to the first day of MEDICA, the world forum for medicine, the Diagnostics Partnering Conference (DxPx Conference) will take place in Düsseldorf, bringing together stakeholders in the diagnostics and research tool industry. The DxPx Conference focuses on discovering technologies, finding financing and investment opportunities and forming collaborative partnerships.
Performance diagnostics: success in sports – testing the limits of performance
01/07/2019
Stationary or mobile - competitive athletes rely on regular health assessments. They must deliver peak performance and be physically fit during competitions. But when do they reach their physical limits? Are there any devices that provide information, no matter where the test subject is located?
Sports medicine - performance values in best health
01/07/2019
Those who integrate physical activities into their own lifestyle live healthier and more balanced. But where are the physical limits? Can health status measurements also be carried out on the road? Discover more about how sports medical examinations contribute to maintain performance and minimize health risks in our Topic of the Month.
Sports medicine – keep moving to stay healthy
01/07/2019
Physical activity plays a big role in today's society. Whether you are an amateur or professional athlete – incorporating exercise into your life positively impacts your mental and physical health. Ideally, sport should be fun, pressure-free and not overburden you. But can you measure individual performance and align it with sports?
Walking is an issue of mind over matter – how robots assist rehabilitation
03/06/2019
Humans are living longer than ever but still want to continue to live independently as they age. Meanwhile, our motor and cognitive abilities decline as we age, sometimes as the effects of a stroke. The number of people in need of long-term care is growing at breakneck speed. At the same time, fewer and fewer young people choose stressful careers as caregivers.
Of exoskeletons and service robots – the future of rehabilitation
03/06/2019
For most people, enjoying a good quality of life means having the ability to move freely, safely and independently. Intensive and costly rehabilitation is needed if this is no longer an option after a stroke for example. We are introducing some projects that deliver innovative robotic solutions.
Robotics – rehab with motors and sensors
03/06/2019
They work with power, precision and tirelessly. This makes robots an ideal instrument for rehabilitation. In gait or motor training, movement sequences must be repeated thousands of times so that they can be learnt anew. What tires the patient and costs the therapist's time can easily be managed by robot-assisted systems. Learn more about the possibilities of robotics in rehabilitation.
mHealth: Atrial fibrillation detection – App supports heart health
08/05/2019
Atrial fibrillation is the most common type of persistent cardiac arrhythmia (irregular heart rhythm). Researchers estimate that 1.8 million Germans are presently affected by this disease. The condition is difficult to diagnose, frequently goes undetected and may result in a stroke. A new smartwatch medical app is designed to help patients detect atrial fibrillation before it’s too late.
Functional imaging: a look at the command center
01/04/2019
All information from our body and the environment converges in our brain and is transformed into reactions in milliseconds. It is essential for medicine and research to know what our switching centre looks like. Functional methods are used to observe it more closely during work.
Stroke: 4D brain perfusion accelerates treatment
01/04/2019
In an ischaemic stroke, rapid treatment is essential. In this moment good imaging data is particularly important to enable doctors to make the best possible decision for therapy. Modern CT scanners are increasingly being used to assess stroke patients because they can show the blood flow to the brain over time.
Functional imaging: what makes the brain tick?
01/04/2019
Our brain is the command center of our body. This is where all information and impressions are collected and converted into responses and movements. Modern imaging techniques offer physicians and researchers unique insights into the actions of the human central nervous system. The functional imaging technique allows them to watch our brain in action.
Blood Sugar Monitoring: Using Infrared Instead of Invasive Techniques
22/03/2019
Over six million people in Germany have diabetes. It is estimated that almost 400 million people are affected by this disease worldwide. Diabetes sufferers must prick their fingers several times a day to monitor their blood sugar.
Orthopedic implant: More comfortable thanks to full weight-bearing capacity
08/03/2019
Orthopedic implants – they are a necessity when it comes to congenital or acquired limb length discrepancies. However, full weight-bearing during the limb lengthening process is not feasible with previous implant models. For the first time, the 3D Surgery division at the Medical Center of the University of Munich has succeeded in using an implant that facilitates immediate weight-bearing.
React early, breathe free – comprehensive COPD management
01/03/2019
COPD is considered the third most common cause of death worldwide and mainly affects smokers. It is not curable, but with the right combination of early diagnosis, therapy and self-management, a significant part of the quality of life can be regained. The comprehensive care is supported by various devices and technical tools. Learn more about the all-round care of COPD in our Topic of the Month.
Comprehensive Treatment: It’s All About Breathing
01/03/2019
Coughing, airway obstruction, difficulty breathing: Chronic obstructive pulmonary disease (COPD) is an umbrella term used to describe progressive and currently incurable lung diseases. The innovative solutions of Philips Respironics help patients to manage each stage of the disease and their medication intake, train the respiratory system and provide respiratory support.
All-round care for COPD: diagnosis, treatment, self-management
01/03/2019
COPD affects more than 200 million people in the world. Those affected by this chronic pulmonary disease are often slow to notice the symptoms and get a medical diagnosis. This results in secondary complications and high medical costs. That's why an early diagnosis, comprehensive treatment, and frequent monitoring are very important. Various devices and tools support this all-round care.
Restoring Pulmonary Function
01/03/2019
People suffering from lung disease temporarily need ventilator support because they are unable to breathe naturally. Mechanical ventilation is designed to ensure the survival of these patients. The goal is to adapt the ventilator settings and tailor them the patient's specific needs and prevent lung tissue damage.
Gentle medication for the little ones – with every breath
22/02/2019
According to the WHO, ten percent of babies worldwide are born prematurely. Since most organs of these tiny babies have not fully developed yet, it can quickly lead to complications and disorders and most notably affect the lungs of the premature infants. What's more, infections require gentle treatment, as the preemies themselves are fragile and susceptible – making this a challenging situation.
Organ-on-a-chip - the mini organs of the future?
01/02/2019
So far in vitro methods and animal experiments have been used to determine the causes of diseases, research therapeutic approaches and predict the effect of drugs. Organ-on-a-chip models now offer a more accurate and ethically justifiable alternative. Find out more about the models, their advantages and future developments in our Topic of the Month.
Organ-on-a-chip – Organs in miniature format
01/02/2019
In vitro processes and animal tests are used to develop new medications and novel therapeutic approaches. However, animal testing raises important ethical concerns. Organ-on-a-chip models promise to be a feasible alternative. In a system the size of a smartphone, organs are connected using artificial circulation.
AI ensures dynamic sitting
22/01/2019
Whether in the office, at school or behind the wheel: we spend a lot of time sitting and often stay in the same position for too long. The possible side effects are stiffness, back problems and pain. The SensA-Chair smart seating solution combats decreased mobility and ensures dynamic sitting.
Better living thanks to telemedicine – "TelePark"- project targets patients with Parkinson’s disease
08/01/2019
Parkinson's disease is a progressive nervous system disorder that primarily affects movement of patients and makes their everyday lives very challenging. It also makes regular doctor appointments and treatment sessions necessary. "TelePark" - a project that collects different movement-related parameters using sensors and apps is designed to improve the quality of life for Parkinson’s patients.
Diabetes digital – smart support for diabetics
02/01/2019
Monitoring blood sugar levels, counting carbohydrates, calculating insulin doses, and keeping accurate records - diabetes is a data-intensive disease that demands a lot of self-discipline and attention from the patients. Some concerns are patients neglecting to keep a food journal, "fudged" test results or calculation errors. Digital solutions help patients easily manage the large volumes of data.
DiaDigital: making sense of diabetes apps
02/01/2019
While they are very useful, health apps have one major drawback: anyone can release and distribute them unchecked. Only some apps require medical device certification. So how can users spot a great, safe and useful app? When it comes to diabetes apps, the “DiaDigital” seal of distinction is the answer.
Blood glucose monitoring of tomorrow - modern diabetes therapies
02/01/2019
There are 425 million people with diabetes in the world. Heart problems, kidney failure or blindness - these can all be consequences of the metabolic disease. Diabetes patients now have the possibility of being treated digitally.
A clean kidney: Break then glue
08/11/2018
Not enough exercise, an unhealthy diet: Kidney stones develop when urine contains too many insoluble compounds and are now one of the most common diseases worldwide. The ailment annually affects 1.2 million people in Germany alone. The stones are broken up and taken out via endoscopic surgery. Now it’s possible to remove even the tiniest residual fragments. The solution: a biocompatible adhesive.
Healthy aging: further research needed on measurement methods in geriatrics
22/10/2018
Today’s society is faced with an aging population. The past has seen the development of many methods for measuring body composition in older adults. However, some of these techniques are not available to medical practices and hospital facilities or are in dire need of optimization.
Exercise Prescription for Health: sports instead of pills
08/10/2018
Did you know that we can influence up to 50 percent of our health ourselves? If we eat a balanced diet and exercise regularly, this not only ensures longer independence in old age. Diseases can also be treated with exercise. But in many cases, physicians and patients still rely more on medication than on exercise.
Back pain: The research project Ran Rücken is intended to help
10/09/2018
About eight in ten Germans suffer from back pain during their lifetime. Too much or the wrong movements can also cause problems. "Ran Rücken", the interdisciplinary research project aims to determine the right minimum dose of exercise that proves effective. (Explanatory note: "Ran Rücken" can be loosely translated as "Target the Back")
Biomechanical measuring systems – motion and posture analysis in orthopedics
21/06/2018
Biomechanical measuring systems are used in orthopedics to diagnose and treat misalignments and diseases. The Velamed Company uses its high-tech solutions to measure biomechanical parameters that enable a holistic analysis of human movement and posture. We took a closer look at how this works.
The cure is in the capsule: carbon monoxide to treat chronic inflammation
22/05/2018
This unusual ally can be extremely valuable in the fight against inflammation in the body: CO (carbon monoxide). As a therapeutic gas, it also promises relief for inflammatory gastrointestinal diseases. Having said that, it is difficult to transport the active ingredient to the exact desired location.
Ventricular fibrillation – Using ultrasound to detect its causes
17/05/2018
Ventricular fibrillation is a life-threatening condition that occurs when the heart muscle exhibits a rapid, erratic beat. The cause might be a circulatory system disease or heart attack. Researchers in Göttingen are now developing an ultrasound technique to get to the bottom of ventricular fibrillation and cardiac arrhythmias and facilitate better treatment options.
Organ Care System: treatment under extreme conditions
08/05/2018
Multidrug-resistant organisms that are treated with a dosage that exceeds the regular dose a hundred times and at temperatures of over 40 degrees Celsius – the human organism is unable to handle it. Yet if the diseased organ is treated outside of the body, extreme conditions are an option. For the first time, physicians have succeeded in treating a severe case of pneumonia by using the OCS.
Personalized cancer medicine – Best possible treatment with TherapySelect
30/04/2018
Medicine is getting more and more personalized. This is particularly interesting for oncology, since a cancer is as individual as the respective patient. When choosing a therapy, both the characteristics of the tumor and the personal characteristics of the patient must be considered. To see exactly what this looks like, we visited the diagnostics company TherapySelect, based in Heidelberg.
Cells in space – extraterrestrial approaches in cancer research
22/02/2018
Here on Earth, all experiments are bound by gravitation. Yet, freed from gravity's grip, tumor cells, for example, behave in an entirely different way. As part of the "Thyroid Cancer Cells in Space" project by the University of Magdeburg, smartphone-sized containers carrying poorly differentiated thyroid cancer cells are sent into space.