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Image: Green and purple colored image of cells; Copyright: Helmholtz Zentrum München/Donovan Correa-Gallegos

Regenerative medicine: Fascia are a repository of mobile scar tissue

06.12.2019

Abnormal scarring is a serious threat resulting in non-healing chronic wounds or fibrosis. Scars form when fibroblasts, a type of cell of connective tissue, reach wounded skin and deposit plugs of extracellular matrix.
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Image: view on the hands of a laboratory worker; Copyright: K. Dobberke für Fraunhofer ISC

Tissue Engineering: new ways to avoid animal testing

26.11.2019

Around 60 international experts met on November 7 at the Fraunhofer Institute for Silicate Research ISC in Wuerzburg to report on the state of the art in the field of 3D tissue models and prevention of animal experiments in the development of pharmaceuticals and medical devices.
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Image: Man using a machine for producing cells; Copyright: Empa

Bone: dissolving screws

07.11.2019

Where bones fracture, surgeons often have to join the fragments with implants. Magnesium orthopaedic screws, which over time dissolve in the body, spare patients another operation after healing is completed and reduce the risk of infection. To develop optimized alloys and orthopaedic screws with functionalized surfaces, Empa researchers are now investigating magnesium corrosion.
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Image: material with scaffold structure; Copyright: Tomsk Polytechnic University

Regenerative medicine: material for cell immune response

04.11.2019

Scientists of Tomsk Polytechnic University jointly with the University of Montana (USA) proposed a new promising material for regenerative medicine for recovery of damaged tissues and blood vessels.
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Image: blood vessel; Copyright: panthermedia.net/thelightwriter

Blood vessels: overly permeable

09.10.2019

In Germany alone there are around 400,000 patients who suffer from chronic inflammatory bowel diseases. For the first time, researchers have discovered that dysfunctions in blood vessels play a significant role in the development of such diseases. In experimental model systems, the progression of the disease slowed down significantly by eliminating these dysfunctions.
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Image: scientist researches with light; Copyright: panthermedia.net / lightpoet

Optoceutics: A new technique using light for regenerative medicine

03.10.2019

Using light to facilitate the formation of new blood vessels: it is the breakthrough outcome of a research study carried out by researchers at Istituto Italiano di Tecnologia (IIT) in Milan (Italy). The study was published in Science Advances.
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Image: Printer head on a solvent-cast 3D printer depositing the functionalized polymer inks layer-by-layer from a needle; Copyright: Lehigh University/Stephanie Veto

Regenerative medicine: biofabrication for multiple tissues

01.10.2019

Organs, muscles and bones are composed of multiple types of cells and tissues that are carefully organized to carry out a specific function. For example, kidneys are able to filter waste from the blood because of how their specialized cells and tissues are arranged. Disrupting this organization dramatically affects how cells and tissues do their job effectively.
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Image: Man with mouthguard and laboratory glasses holding Petri dish up; Copyright: panthermedia.net/kasto

Cardiac Tissue Engineering: a heart out of the Petri dish

23.09.2019

For patients waiting for donor organs, every day can mean the difference between life and death. Making things even more complicated is the fact that not every organ is a compatible match with the patient. It would mean enormous progress if we could grow organs from the patient's own cells in the lab. That's why patients with heart disease place big hope in tissue engineering.
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Image: tissue grown on a capillary bridge; Copyright: MPI of Colloids and Interfaces/ Sebastian Ehrig

Tissue engineering: Form is function

12.09.2019

Liquid-like tissue behavior is a key principle for the formation of structures in biological systems. Researchers at the Max Planck Institute of Colloids and Interfaces in Potsdam have shown that growing bone tissue behaves like a viscous liquid on long time scales, thereby accepting forms with minimal surface area.
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Image: dna strings in yellow, blue and red; Copyright: panthermedia.net/khenghotoh

DNA: construction kit replaces expensive antibody medication

11.09.2019

Researchers at KU Leuven in Belgium have developed a technique to make sheep produce new antibodies simply by injecting the DNA building blocks. This approach is much cheaper and more efficient than producing antibodies industrially and administering them afterwards. The study in animals with a similar size as humans brings us a step closer to the clinical use of antibody gene therapy.
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Image: Marathon runner; Copyright: panthermedia.net/adamgregor

Sports medicine – keep moving to stay healthy

01.07.2019

Physical activity plays a big role in today's society. Whether you are an amateur or professional athlete – incorporating exercise into your life positively impacts your mental and physical health. Ideally, sport should be fun, pressure-free and not overburden you. But can you measure individual performance and align it with sports?
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Image: View over the shoulders of two doctors at a screen showing a model of a heart; Copyright: panthermedia.net/Wavebreakmedia ltd

Regenerative heart valves: from simulation to replacement

23.07.2018

Every year, more than 250,000 patients worldwide receive heart valve implants. Children require repeated replacement surgery because their bodies are still growing, the prosthetic heart valves are not. Regenerative heart valves solve this problem. Until now, we have only been able to monitor how these living implants develop in the body after the fact. Computer models now make this predictable.
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Image: Two hands are holding a tubular frame that is carrying a glistening wet, white tube; Copyright: Leibniz University of Hanover/Institute of Technical Chemistry

Tissue engineering: how to grow a bypass

23.04.2018

A bypass is a complicated structure. It is either made of synthetic materials that can cause blood clots and infections or created by using the patient’s veins. However, the latter often does not yield adequate material. A newly developed bioreactor could solve this problem in the future. It is designed to tissue engineer vascular grafts by using the body’s own material.
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