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Juliet Percival/MPI für Biochemie
New method revolutionizes cancer diagnosis
24/05/2022
A German-Danish team led by Prof. Matthias Mann has developed a ground-breaking technology called 'Deep Visual Proteomics'. This method provides researchers and clinicians with a protein read-out to understand cancer at single cell-type resolution. The technology was published in the journal Nature Biotechnology and demonstrates its potential in a first application to cancer cells.
AG Chumduri
Cervix: Research progress thanks to mini organs
23/05/2022
Life-like organ replicas - so-called 3D organoids - are a good way to research disease processes. A team from the University of Würzburg has now presented a kind of blueprint for such a model of the cervix.
HZI/Manfred Rohde
A bright spot for microbiological diagnostics
19/05/2022
HZI researchers develop molecular probes to detect pathogens in clinical samples.
twenty20photos
Smart pacifier to monitor infant health in the hospital
18/05/2022
A wireless, bioelectronic pacifier could eliminate the need for invasive, twice-daily blood draws to monitor babies’ electrolytes in Newborn Intensive Care Units or NICUs.
gpointstudio
Nanosensor platform could advance detection of ovarian cancer
18/05/2022
Lehigh University researchers, part of multi-institution team, use the fluorescence of carbon nanotubes and machine learning to create a ‘spectral fingerprint’ of a hard-to-diagnose cancer.
Fraunhofer ILT, Aachen
Process chains for isolation and analysis: from single cells to organoids
17/05/2022
Researchers at the Fraunhofer Institute for Laser Technology ILT are working on new tools for the preparation and analysis of single cells and cell assemblies. The team developed the "Liftoscope", a system for cell sorting for subsequent cultivation that can analyze and transfer biomaterials precisely and in a way that is gentle on cells.
Kacey Ronaldson-Bouchard/Columbia Engineering
Plug-and-play organ-on-a-chip can be customized to the patient
05/05/2022
Major advance from Columbia Engineering team demonstrates first multi-organ chip made of engineered human tissues linked by vascular flow for improved modeling of systemic diseases like cancer
The Biodesign Institute at Arizona State University
A sharper image for proteins
05/05/2022
To fully understand proteins and their myriad functions, researchers have developed sophisticated means to see and study them using advanced microscopy, enhanced light detection, imaging software and the integration of advanced hardware systems. A new study from Arizona State University describes a new technique that promises to revolutionize the imaging of proteins and other vital biomolecules.
Antonie Bierling/TUD
Electronic noses to track down body odors
03/05/2022
Human body odor is influenced by diet, inflammatory processes, and hormone balance, among other factors, and consequently changes in body odor can provide clues to disease - sometimes much earlier than through currently established diagnostic methods.
umg/Institut für Auditorische Neurowissenschaften
Decoding the hearing: ERC grant for Tobias Moser
03/05/2022
Tobias Moser, MD, Director of the Institute for Auditory Neuroscience at the University Medical Center Göttingen (UMG) was awarded an Advanced Grant of the European Research Council (ERC). The ERC supports his research project "Solving the dynamic range problem of hearing: deciphering and harnessing cochlear mechanisms of sound intensity coding (DynaHear)" over five years with 2,5 million euros.
Zoltán Cseresnyés/Leibniz-HKI
How do fungal infections spread in the human lung?
22/04/2022
A chip model allows us to observe growth in the tissue.
microgen
Want to 3D print a kidney? Start by thinking small
21/04/2022
Stevens computational model aims to accelerate microfluidic bio-printing that opens up a pathway for 3D printing any kind of organ at any time.
Unimedizin Magdeburg
HFSP funding to study synaptic lipid signatures
19/04/2022
The astonishing capacity of the brain to process and store information crucially relies on properly functioning synapses. They provide the connecting entities within neural circuits and their properties define circuit function.
Sarah Needs, Cygnus smartphone testing technology
Dengue detection smartphone tech shows new hope for low-cost diagnostics
14/04/2022
Accurate home testing could be used for a wider range of illnesses, as new research shows the capability of smartphone-powered tests for Dengue Fever.
Abigail K. Grosskopf
Simple delivery method enhances promising cancer treatment
13/04/2022
One cutting-edge cancer treatment exciting researchers today involves collecting and reprogramming a patient’s T cells – a special set of immune cells – then putting them back into the body ready to detect and destroy cancerous cells. Although effective for widespread blood cancers like leukemia, this method rarely succeeds at treating solid tumors.
MPI für molekulare Biomedizin / Yotam Menuchin-Lasowski
There is more to SARS-CoV-2 than meets the eye
29/03/2022
SARS-CoV-2 not only causes respiratory infections. It can also enter the retina and cause damage. It is unclear which retinal structures are infected and whether the damage is a direct or indirect consequence of infection.
PantherMedia / pinkblue (YAYMicro)
TU Munich: EU funding in medicine and biotechnology
28/03/2022
Deep learning algorithms to diagnose back pain, artificial enzymes for energy conversion facilities and a Covid-19 drug: the European Research Council (ERC) has announced funding for projects at the Technical University of Munich.
PantherMedia / Craig Robinson
BMBF funds junior research group for 3D bioprinting project
25/03/2022
For her research project on three-dimensional "printing" of the human cornea, Junior Professor Dr Daniela Duarte Campos of Heidelberg University has been awarded financial support of approximately 2.2 million euros through the "NanoMatFutur" funding competition sponsored by the Federal Ministry of Education and Research.
DWI – Leibniz Institute for Interactive Materials
ERC Consolidator Grant for Laura De Laporte and the "HEARTBEAT" project
23/03/2022
Scientist Laura De Laporte (DWI – Leibniz Institute for Interactive Materials and RWTH Aachen University) has been awarded one of the most highly endowed research grants of the European Research Council (ERC): an ERC Consolidator Grant
Georgia Tech photo
Biosensors for quick assessment of cancer treatment
16/03/2022
Immune checkpoint blockade (ICB) inhibitors have transformed the treatment of cancer and have become the frontline therapy for a broad range of malignancies. It’s because they work better than the previous standard of care.
HZDR / Amac Garbe
Pulsed magnetic fields to fight neurodegenerative diseases
10/03/2022
In motor neuron diseases of the nervous system, such as amyotrophic lateral sclerosis (ALS), commands can no longer be sent to the muscles.
Virginia Tech
Grant to improve Lyme disease diagnostics and therapeutics
10/03/2022
Lyme disease is carried by black-legged ticks and infects people when they are bitten and transmit the bacterium Borrelia burgdorferi. Black-legged ticks are especially common in the northeastern United States, and people are exposed to the ticks usually during outdoor activities.
PantherMedia/benschonewille
Technology against organ shortage – Support for the successful transplant
03/02/2022
The waiting time for a donor organ is long nowadays since the need for organs vastly exceeds their availability. But we have possibilities to improve the situation and help as many people as possible to survive despite organ failure: Some organ functions can already be substituted by technology. But medicine is also researching ways to make more organs available for transplant.
Charité – Universitätsmedizin Berlin
Machine Perfusion: Increasing the Safety of Marginal Organ Transplants
03/01/2022
The shortage of donor organs is a major global issue. An aging population, a reluctance towards organ donation, and logistical challenges related to organ shipping play an important role in this setting. Machine perfusion can be a way to expand and preserve the donor pool for eligible transplant recipients.
PantherMedia/Richmanphoto
COPD: How long before the implantable lung is here?
03/01/2022
Extracorporeal membrane oxygenation (ECMO) is often a last resort treatment for patients with acute respiratory failure. The method uses an external pump to circulate blood through an artificial lung back into the bloodstream. However, the use of ECMO for long-term support is not possible for patients with chronic respiratory failure.
PantherMedia/NikD51
Donor organs: Solving the shortage with technology
03/01/2022
Patients waiting for a donor organ must have a lot of patience and a bit of luck. Aging and a rise in chronic disease prevalence means the need for donor organs is much greater than the number that is available. To help those who need organ transplants, scientists must create new technologies.
PantherMedia/Meseritsch Herby
Implants for the senses – Hearing and seeing with technology
01/12/2021
We can replace certain functions of the body with implants nowadays, others we cannot. When it comes to the human senses, we are still quite at the beginning. The technologies and materials we can use are way to coarse compared to our nervous system. But implants can also help us to maintain senses.
Autonomous medical devices: running well in your body
01/02/2021
In theory, autonomous medical technologies can be used in a diagnostic or therapeutic capacity inside the body under certain conditions. This may not sound like a new invention at first. After all, implantable cardioverter-defibrillators have monitored and fixed abnormal heart rhythm for many years.
Autonomous medical technology: independently in the body
01/02/2021
Therapies need to be carried out with high reliability by trained personal. This will not change in the future. But maybe we will be able to let systems in the patient’s body do some of the work. Some approaches are already aiming to make implants more independent so they will be able to flexibly react to changes. Read more in our Topic of the Month!
Bioprinting: life from the printer
01/12/2020
It aims at the production of test systems for drug research and gives patients on the waiting lists for donor organs hope: bioprinting. Thereby biologically functional tissues are printed. But how does that actually work? What are the different bioprinting methods? And can entire organs be printed with it? These and other questions are examined in our Topic of the Month.
Multi-photon lithography: printing cells with micrometer accuracy
01/12/2020
How do cells react to certain drugs? And how exactly is new tissue created? This can be analyzed by using bioprinting to embed cells in fine frameworks. However, current methods are often imprecise or too slow to process cells before they are damaged. At the TU Vienna, a high-resolution bioprinting process has now been developed using a new bio-ink.
"Cells are highly sensitive" – material development for bioprinting
01/12/2020
The big hope of bioprinting is to someday be able to print whole human organs. So far, the process has been limited to testing platforms such as organs-on-a-chip. That's because the actual printing process already poses challenges. Scientists need suitable printing materials that ensure the cell's survival as it undergoes the procedure. The Fraunhofer IGB is researching and analyzing this aspect.
SmartLab: all-in-one automation, digitalization, and miniaturization
01/09/2020
Laboratories have to analyze and interpret an ever-increasing number of samples for research and diagnostic services, generating lots of data in the process. At the same time, labs are required to produce quality results and operate with speed. Processes that could once be managed using laboratory notebooks and isolated systems must become smart in the future to improve lab efficiency.
PantherMedia/everythingposs
Israeli medical devices showcase digital innovations at MEDICA
24/08/2020
For the annual MEDICA trade fair, companies from all over the world assemble in Düsseldorf. The Israel Export Institute has been a part of it for the last couple of years. They present medical devices and digital innovations from different Israeli companies at their joint booth.
Regenerative medicine: creating a new body?
03/02/2020
Regenerative medicine aims to repair the human body after injuries, accidents or major cancer surgery. Unfortunately, we are still not at a stage where this process can achieve optimal results for every conceivable situation. Having said that, various new methods are on the cusp of breakthrough.
Angiogenesis: light shows blood vessels the way
03/02/2020
Regenerative medicine aims to replace damage in the body with functional tissue and restore normal function. The first defense for large defects are implants made of hydrogels, designed to promote cell growth. They need their own blood supply, which is a problem when it comes to larger implants because you cannot regulate where and how the blood vessels grow - until now.
rhCollagen: genetically engineered building block for regenerative medicine
03/02/2020
Collagen is the stuff that holds our bodies together and that houses our cells. In regenerative medicine, it is also the stuff that can be applied to wounds to support healing. However, collagen from animal or human sources has some drawbacks for today’s medicine. This is where rhCollagen from the Israeli company CollPlant comes into play.
Organ-on-a-chip systems: limited validity?
01/02/2019
Organ-on-a-chip systems are technically a great enhancement of medical research because they facilitate testing of active ingredients on cell cultures in the chambers of a plastic chip. This replaces animal testing and improves patient safety. That being said, they are not a true-to-life replication of the human body and can only simulate a few functions and activities.
panthermedia.net/Mario Hahn
Early detection: Tattoo signals cancer – and more
09/07/2018
People who are not ill and do not show any symptoms typically do not visit the doctor. And while most people know that preventive medical checkups for cancer, for example, are important, they still avoid them. They tend to be very hesitant because the doctor might detect a serious illness. In the future, a new type of implant could make it easier to go to a screening test.
Leibniz University of Hanover/Institute of Technical Chemistry
Tissue engineering: how to grow a bypass
23/04/2018
A bypass is a complicated structure. It is either made of synthetic materials that can cause blood clots and infections or created by using the patient’s veins. However, the latter often does not yield adequate material. A newly developed bioreactor could solve this problem in the future. It is designed to tissue engineer vascular grafts by using the body’s own material.