18.06.2019Researchers at Ben-Gurion University of the Negev (BGU) and Cedars-Sinai Medical Center in Los Angeles have, for the first time, duplicated a patient's blood-brain barrier (BBB), creating a human BBB chip with stem cells, which can be used to develop personalized medicine and new techniques to research brain disorders.
17.06.2019Like airport security barriers that either clear authorized travelers or block unauthorized travelers and their luggage from accessing central operation areas, the blood-brain-barrier (BBB) tightly controls the transport of essential nutrients and energy metabolites into the brain and staves off unwanted substances circulating in the blood stream.
06.06.2019Scientists at Texas A&M University are harnessing the combined power of organic nanomaterials-based chemistry and a natural product found in crustacean exoskeletons to help bring emergency medicine one step closer to a viable solution for mitigating blood loss, from the hospital to the battlefield.
28.05.2019The production of artificial organs is a hot research topic. In the near future, artificial organs will compensate for the lack of organ donations and replace animal experiments. Although there are already promising experiments with 3D printers that use a "bio-ink" containing living cells, a functional organ has never been created in this way.
15.05.2019New active substances that are suitable for drugs are initially tested in animal experiments. However, the results cannot always be transferred to the human organism. At the Karlsruhe Institute of Technology, Prof. Ute Schepers from vasQlab explains how active substances can be tested in human tissue without endangering human health.
15.05.2019Bioengineers have cleared a major hurdle on the path to 3D printing replacement organs with a breakthrough technique for bioprinting tissues. The innovation allows scientists to create exquisitely entangled vascular networks that mimic the body's natural passageways for blood, air, lymph and other vital fluids.
10.05.2019A simple innovation the size of a grain of sand means we can now analyse cells and tiny particles as if they were inside the human body. The new micro-device for fluid analysis will enable more tailored experiments in drug development and disease research via new 'organ-on-chip' systems.
06.05.2019To model human health and disease, organ-on-a-chip technology mimics the human body's organ structure, functionality and physiology in a controlled environment. These miniature systems, which serve as accurate models of various organs from the heart and lungs to the gut and the kidneys, can use a patient's own cells to test drugs and understand disease processes.
06.05.2019A faculty-researcher at Rochester Institute of technology has developed a prototype micro device with bio-sensors that can detect the deadly Ebola virus. With this type of device, those infected can be treated earlier, and the early detection process can potentially decrease the spread of infections.
25.04.2019Researchers have designed a new type of adhesive patch that can be placed directly on the heart and may one day help to reduce the stretching of heart muscle that often occurs after a heart attack.
15.04.2019A new technique for the decontamination of organs before transplantation using ultraviolet and red light irradiation has been developed by Brazilian and Canadian researchers and is described in an article published in the journal Nature Communications.
12.04.2019North Carolina State University researchers have developed a technique to improve the characteristics of engineered tissues by using ultrasound to align living cells during the biofabrication process.
08.04.2019With the growth of 3D printing, it's entirely possible to 3D print your own prosthetic from models found in open-source databases. But those models lack personalized electronic user interfaces like those found in costly, state-of-the-art prosthetics.
01.04.2019A research team led by biophysical chemist Professor Edward Lemke has engineered a designer organelle in a living mammalian cell in a new complex biological translation process. The created membraneless organelle can build proteins from natural and synthetic amino acids carrying new functionalities.
01.04.2019High-resolution optical microscopy methods promise breakthroughs in materials science, biology, and medicine. Today, their possibilities basically reach those of scanning electron microscopy.
22.03.2019The heart exerts muscular force by contracting numerous contractile units of the heart muscle. Biologists at Münster University have found out that a specific motor protein is responsible for the assembly and mechanical stability of these contractile units in the heart. The study has been published in “The Journal of Biological Chemistry”.
01.02.2019Organ-on-a-chip systems are technically a great enhancement of medical research because they facilitate testing of active ingredients on cell cultures in the chambers of a plastic chip. This replaces animal testing and improves patient safety. That being said, they are not a true-to-life replication of the human body and can only simulate a few functions and activities.
09.07.2018People who are not ill and do not show any symptoms typically do not visit the doctor. And while most people know that preventive medical checkups for cancer, for example, are important, they still avoid them. They tend to be very hesitant because the doctor might detect a serious illness. In the future, a new type of implant could make it easier to go to a screening test.
23.04.2018A bypass is a complicated structure. It is either made of synthetic materials that can cause blood clots and infections or created by using the patient’s veins. However, the latter often does not yield adequate material. A newly developed bioreactor could solve this problem in the future. It is designed to tissue engineer vascular grafts by using the body’s own material.
01.06.2017After a stroke or as a result of aging, there are many situations when people are impaired in their walking ability and rely on a personal assistant or auxiliary aids and services. The XoSoft Project offers a solution: a soft exoskeleton that can be worn like a pair of leggings and stiffens or softens, depending on the situation.