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Blood-brain barrier chip: using stem cells for the first time
18.06.2019
Researchers at Ben-Gurion University of the Negev (BGU) and Cedars-Sinai Medical Center in Los Angeles have, for the first time, duplicated a patient's blood-brain barrier (BBB), creating a human BBB chip with stem cells, which can be used to develop personalized medicine and new techniques to research brain disorders.
Blood-Brain Barrier Chip: in vivo-like drug and antibody transport
17.06.2019
Like airport security barriers that either clear authorized travelers or block unauthorized travelers and their luggage from accessing central operation areas, the blood-brain-barrier (BBB) tightly controls the transport of essential nutrients and energy metabolites into the brain and staves off unwanted substances circulating in the blood stream.
Wound care: new nanoscale bioabsorbable dressing
06.06.2019
Scientists at Texas A&M University are harnessing the combined power of organic nanomaterials-based chemistry and a natural product found in crustacean exoskeletons to help bring emergency medicine one step closer to a viable solution for mitigating blood loss, from the hospital to the battlefield.
Tissue Engineering: producing tissue and organs through lithography
28.05.2019
The production of artificial organs is a hot research topic. In the near future, artificial organs will compensate for the lack of organ donations and replace animal experiments. Although there are already promising experiments with 3D printers that use a "bio-ink" containing living cells, a functional organ has never been created in this way.
Multi-organ chips: Drug research without animal testing at vasQlab
15.05.2019
New active substances that are suitable for drugs are initially tested in animal experiments. However, the results cannot always be transferred to the human organism. At the Karlsruhe Institute of Technology, Prof. Ute Schepers from vasQlab explains how active substances can be tested in human tissue without endangering human health.
Organ bioprinting gets a breath of fresh air
15.05.2019
Bioengineers have cleared a major hurdle on the path to 3D printing replacement organs with a breakthrough technique for bioprinting tissues. The innovation allows scientists to create exquisitely entangled vascular networks that mimic the body's natural passageways for blood, air, lymph and other vital fluids.
Organ-on-a-chip: mini-centrifuge for simpler study of blood cells
10.05.2019
A simple innovation the size of a grain of sand means we can now analyse cells and tiny particles as if they were inside the human body. The new micro-device for fluid analysis will enable more tailored experiments in drug development and disease research via new 'organ-on-chip' systems.
Gut-on-a-chip: personalized treatment for Crohn's disease
06.05.2019
To model human health and disease, organ-on-a-chip technology mimics the human body's organ structure, functionality and physiology in a controlled environment. These miniature systems, which serve as accurate models of various organs from the heart and lungs to the gut and the kidneys, can use a patient's own cells to test drugs and understand disease processes.
Microfluidic chip to better detect Ebola virus
06.05.2019
A faculty-researcher at Rochester Institute of technology has developed a prototype micro device with bio-sensors that can detect the deadly Ebola virus. With this type of device, those infected can be treated earlier, and the early detection process can potentially decrease the spread of infections.
Implanted heart patch could limit muscle damage after heart attack
25.04.2019
Researchers have designed a new type of adhesive patch that can be placed directly on the heart and may one day help to reduce the stretching of heart muscle that often occurs after a heart attack.
Radiation: eliminating bacteria and viruses
15.04.2019
A new technique for the decontamination of organs before transplantation using ultraviolet and red light irradiation has been developed by Brazilian and Canadian researchers and is described in an article published in the journal Nature Communications.
Ultrasound aligns living cells in bioprinted tissues
12.04.2019
North Carolina State University researchers have developed a technique to improve the characteristics of engineered tissues by using ultrasound to align living cells during the biofabrication process.
Orthopedics: personalized prosthetics from the 3D printer
08.04.2019
With the growth of 3D printing, it's entirely possible to 3D print your own prosthetic from models found in open-source databases. But those models lack personalized electronic user interfaces like those found in costly, state-of-the-art prosthetics.
Laboratory technology: designer organelles in cells
01.04.2019
A research team led by biophysical chemist Professor Edward Lemke has engineered a designer organelle in a living mammalian cell in a new complex biological translation process. The created membraneless organelle can build proteins from natural and synthetic amino acids carrying new functionalities.
Laboratory technology: New way of optical visualization?
01.04.2019
High-resolution optical microscopy methods promise breakthroughs in materials science, biology, and medicine. Today, their possibilities basically reach those of scanning electron microscopy.
Laboratory technology: New heart muscle component discovered
22.03.2019
The heart exerts muscular force by contracting numerous contractile units of the heart muscle. Biologists at Münster University have found out that a specific motor protein is responsible for the assembly and mechanical stability of these contractile units in the heart. The study has been published in “The Journal of Biological Chemistry”.
Organ-on-a-chip systems: limited validity?
01.02.2019
Organ-on-a-chip systems are technically a great enhancement of medical research because they facilitate testing of active ingredients on cell cultures in the chambers of a plastic chip. This replaces animal testing and improves patient safety. That being said, they are not a true-to-life replication of the human body and can only simulate a few functions and activities.
Early detection: Tattoo signals cancer – and more
09.07.2018
People who are not ill and do not show any symptoms typically do not visit the doctor. And while most people know that preventive medical checkups for cancer, for example, are important, they still avoid them. They tend to be very hesitant because the doctor might detect a serious illness. In the future, a new type of implant could make it easier to go to a screening test.
Tissue engineering: how to grow a bypass
23.04.2018
A bypass is a complicated structure. It is either made of synthetic materials that can cause blood clots and infections or created by using the patient’s veins. However, the latter often does not yield adequate material. A newly developed bioreactor could solve this problem in the future. It is designed to tissue engineer vascular grafts by using the body’s own material.
"XoSoft" Project – Wearable Intelligent Exoskeleton
01.06.2017
After a stroke or as a result of aging, there are many situations when people are impaired in their walking ability and rely on a personal assistant or auxiliary aids and services. The XoSoft Project offers a solution: a soft exoskeleton that can be worn like a pair of leggings and stiffens or softens, depending on the situation.