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Image: Man working in a laboratory; Copyright: Cedars-Sinai

COVID-19: virus can infect heart cells in lab dish


A new study shows that SARS-CoV-2, the virus that causes COVID-19, can infect heart cells in a lab dish, indicating it may be possible for heart cells in COVID-19 patients to be directly infected by the virus. The discovery, published today in the journal Cell Reports Medicine, was made using heart muscle cells that were produced by stem cell technology.
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Image: 'Mini-brain' bioengineered from human stem cells; Copyright: Center for Alternatives to Animal Testing (CAAT), Johns Hopkins Bloomberg School of Public Health

Organoids suggest COVID-19 virus can infect human brain cells


A multidisciplinary team from two Johns Hopkins University institutions, including neurotoxicologists and virologists from the Bloomberg School of Public Health and infectious disease specialists from the school of medicine, has found that organoids known as "mini-brains" can be infected by the SARS-CoV-2 virus that causes COVID-19.
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Image: point-of-care diagnostic system; Copyright: NUS Institute for Health Innovation & Technology

Portable COVID-19 diagnostic system for rapid on-site testing


COVID-19 screening can soon be conducted directly at various testing stations, and patients can get their test results in about an hour from the time they get a nasal swab. A team of researchers from the National University of Singapore (NUS) has developed a portable COVID-19 micro-PCR diagnostic system that enables rapid and accurate on-site screening of infectious diseases.
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Image: A female researcher in a protectic suit is working at a laboratory safety bench; Copyright: Sierra Downs, courtesy of the Griffiths Lab/BU NEIDL

Tiny decoy sponges attract coronavirus away from lung cells


Imagine if scientists could stop the coronavirus infection in its tracks simply by diverting its attention away from living lung cells? A new therapeutic countermeasure, announced in a Nano Letters study by researchers from Boston University's National Emerging Infectious Diseases Laboratories (NEIDL) and the University of California San Diego, appears to do just that in experiments.
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Image: Two gloved hands are holding a vial of blood with the label

Biomarkers show clear signs of brain injury with severe COVID-19


Certain patients who receive hospital care for coronavirus infection (COVID-19) exhibit clinical and neurochemical signs of brain injury, a University of Gothenburg study shows. In even moderate COVID-19 cases, finding and measuring a blood-based biomarker for brain damage proved to be possible.
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Image: man running in a lane on a sports field; Copyright: PantherMedia/stetsik

A Safe Return to Sports amid the COVID-19 Pandemic


After professional sports and other sporting activities had been drastically limited to prevent COVID-19 spread, training facilities are now reopening to welcome recreational and competitive athletes. However, due to the ongoing pandemic, restrictions are still in place to lower the risk of human infection. EFSMA presents recommendations on a uniform approach to keeping athletes safe.
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Image: Paul McCray and Stanley Perlman in their laboratory; Copyright: University of Iowa Health Care

Off-the-shelf tool for making mouse models of COVID-19


Until there are effective treatments or vaccines, the COVID-19 pandemic will remain a significant threat to public health and economies around the world. A major hurdle to developing and testing new anti-viral therapies and vaccines for COVID-19 is the lack of good, widely available animal models of the disease.
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Image: symbolic abstract image for Big Data; Copyright: National Center for Translational Sciences

Analytics platform to harness COVID-19 patient data


The National Institutes of Health has launched a centralized, secure enclave to store and study vast amounts of medical record data from people diagnosed with coronavirus disease across the country. It is part of an effort, called the National COVID Cohort Collaborative (N3C), to help scientists analyze these data to understand the disease and develop treatments.
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Image: health care workers with elastomeric masks; Copyright: Highmark Health

Elastomeric masks more durable and less costly option


A cost-effective strategy for health care systems to offset N95 mask shortages due to the Coronavirus Disease 2019 (COVID-19) pandemic is to switch to reusable elastomeric respirator masks, according to new study results. These long-lasting masks, often used in industry and construction, cost at least 10 times less per month than disinfecting and reusing N95 masks meant to be for single use.
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Image: graphic depiction of tracked network of people; Copyright: @UPV

Bluetooth technology to detect COVID-19 cases through smartphone


Today, the tracing is done by hand and this work is slow and inaccurate. Technology can be highly useful: contact tracing with smartphones and smartclocks help find out who has been in contact with an infected person, thanks to the use of localization and communication technologies, such as GPS, cell phone networks, Wi-Fi and Bluetooth," explains Enrique Hernández Orallo.
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Image: hospital ward room with two beds; Copyright: jung

Virus DNA spread across surfaces in hospital over 10 hours


Virus DNA left on a hospital bed rail was found in nearly half of all sites sampled across a ward within 10 hours and persisted for at least five days, according to a new study by UCL and Great Ormond Street Hospital. The study, published as a letter in the Journal of Hospital Infection, aimed to safely simulate how SARS-CoV-2, may spread across surfaces in a hospital.
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Image: graphic depiction of virus cell in the lungs; Copyright: ATS

COVID-19: reducing severe breathlessness and psychological trauma


A new paper published online in the Annals of the American Thoracic Society examines ventilation and medication strategies that can help avoid psychological trauma for severe COVID-19 survivors treated for acute respiratory distress syndrome (ARDS) with mechanical ventilation.
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Image: A computer-generated image of a blue device; Copyright: POLI-USP

Brazilian researchers develop low-cost mechanical ventilators


A group of researchers at the University of São Paulo's Engineering School (POLI-USP) in Brazil have developed a mechanical ventilator that costs only approximately 7% as much as a conventional ventilator. Called Inspire, it has an open patent allowing royalty-free manufacturing, although as a life support device, its distribution is controlled.
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Image: An older man in a suit is showing a small black object in a petri dish; Copyright: Joseph Fuqua II/UC Creative + Brand

Reusable face mask could be answer to PPE shortfall


Engineers at the University of Cincinnati are using a National Science Foundation grant to develop a face mask that can be sterilized with heat for re-use.
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Image: Blurred image of a child that is pushed into a CT; Copyright: PantherMedia/Jayjaynaenae

CT findings of COVID-19 in children 'often negative'


Largest case series (n=30) to date yields high frequency (77%) of negative chest CT findings among pediatric patients (10 months-18 years) with COVID-19, while also suggesting common findings in subset of children with positive CT findings.
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Image: A plastic bag is filled with a transparent fluid; Copyright: Johns Hopkins Medicine

New method to make kidney dialysis fluid for patients with COVID-19


The ongoing COVID-19 pandemic has severely impacted the manufacturing and supply chains for many products. But while shortages of toilet paper, disinfectant cleaners and hand sanitizer get most of the news coverage, the diminishing reserve of one item - kidney dialysis fluid, also known as dialysate - presents a grave threat to the lives of people with acute kidney injury (AKI).
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Image: particles from a simple breath test behind a petri dish with chips ins it; Copyright: Ben-Gurion University

One minute electro-optical coronavirus test


Ben-Gurion University of the Negev's Prof. Gabby Sarusi has developed a one-minute electro-optical test of nose, throat or breath samples that will identify both asymptomatic and affected carriers of the COVID-19 virus in under one minute with greater than 90 percent accuracy.
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Image: Prototype of the UVC LED irradiation system; Copyright: FBH/P. Immerz

Fighting hospital germs with UVC light-emitting diodes


According to the RKI, 400,000 to 600,000 infections with hospital germs occur in Germany every year – about 10,000 to 20,000 people die from them. Since MDR pathogens often cannot be treated with antibiotics, alternative approaches are needed. One promising physical principle is irradiation with UVC light, which can be used to destroy microorganisms without allowing resistances to develop.
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Image: smartphone in ophthalmological use in India; Copyright: Universität Bonn/Sankara Eye Foundation

mHealth: inexpensive retinal diagnostics via smartphone


Retinal damage due to diabetes is now considered the most common cause of blindness in working-age adults. In low- and middle-income countries, an eye examination via smartphone could help to detect changes at an early stage. This is shown by a new study carried out by scientists from the University of Bonn together with colleagues from Sankara Eye Hospital Bangalore (India).
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Image: graphic of pathogens; Copyright: Arek Socha / Pixabay

Hygiene: nano technologies to tackle infection


Next-gen nano technologies that can prevent infection and diagnose disease are set to transform the medical industry as this important UniSA research is awarded more than $2 million dollars under the National Health and Medical Research Council (NHMRC) 2021 Investigator Grants.
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Image: small portable device next to tennis ball; Copyright: Nishiyama K. et al., Sensors and Actuators B: Chemical. April 21, 2020

COVID-19: technology can detect anti-virus antibody in 20 minutes


Researchers have succeeded in detecting anti-avian influenza virus antibody in blood serum within 20 minutes, using a portable analyzer they have developed to conduct rapid on-site bio tests. If a suitable reagent is developed, this technology could be used to detect antibodies against SARS-CoV-2, the causative virus of COVID-19.
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Image: Doctor holding a radiology image; Copyright: PantherMedia / pressmaster

COVID-19: Teleradiology enables social distancing


Remote reading of imaging studies on home PACS workstations can contribute to social distancing, protect vulnerable radiologists and others in the hospital, and ensure seamless interpretation capabilities in emergency scenarios, according to an open-access article published ahead-of-print by the American Journal of Roentgenology (AJR).
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Image: Man is holding an x-ray of the lungs in front of his chest; Copyright: PantherMedia/Jakub Jirsak

COVID-19: low-dose radiographs could reveal lung changes


Researchers at the Technical University of Munich (TUM) have developed an innovative x-ray method for lung diagnostics, which they now plan to test in one of its first applications for diagnosis of the respiratory ailment Covid-19 caused by Coronavirus.
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Image: Physician in white scrubs standing next to a medical device - Dr. Chris McIntyre; Copyright: Lawson Health Research Institute

Canadian team first in world to treat COVID-19 with specialized dialysis


As part of a randomized controlled trial, a team from Lawson Health Research Institute is the first in the world to treat a patient with COVID-19 using a modified dialysis device. The device gently removes a patient's blood, modifies white blood cells and returns them to fight hyperinflammation. It is being tested with critically ill patients at London Health Sciences Centre (LHSC).
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Image: A gloved hand holds a cup with an urine sample; Copyright: PantherMedia/belchonok

COVID-19: kidney inflammation as early warning sign for severe course


Scientists from the University Medical Center Goettingen develop a conceivable course of action for patients with COVID-19 infections to predict severity of systemic disease and complications. Published online in The Lancet.
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Image: An electronic component with a cable and a light; Copyright: Massood Tabib-Azar/University of Utah College of Engineering

Portable, reusable test for COVID-19


University of Utah engineer is developing a fast, reusable test for COVID-19 that works with cellphones.
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Image: A mechanical ventilator bag with a control device; Copyright: Mechanical Ventilator Milano

Physicists design FDA-approved, open-source ventilator


As the spread of COVID-19 sparked a global search for ventilators to help critically ill patients, an international collaboration of particle physicists and engineers pivoted to design a mechanical ventilator made from readily available components.
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Image: grafic depiction of a brain with burst blood vessels; Copyright: PantherMedia/artemida psy

Day against Stroke 2020


This year on 10.05.2020 the Day Against Stroke is being celebrated under the title "The digital helpers are coming!". A stroke is still one of the most frequent causes of death. Every year, around 270,000 people suffer a stroke in Germany alone.
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Image: group of scientists with face masks; Copyright: Cima Universidad de Navarra

New COVID-19 diagnostic platform more efficient than PCR test kits


Cima Universidad de Navarra researchers have developed a large-scale, highly sensitive COVID-19 diagnostic platform more efficient than the commercial PCR test kits currently available. It consists of a ribonucleic acid (RNA) extraction method which allows large quantities of samples to be processed in parallel, independent of commercial extraction test kits.
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Image: four hands under ultraviolet light with traces of something on them; Copyright: Rami A. Ahmed, D.O.

COVID-19: ultraviolet light exposes improper PPE use


Despite the use of personal protective equipment (PPE), reports show that many health care workers contracted the coronavirus disease (COVID-19), which raises substantial concerns about the effectiveness of the PPE. Highly sought after PPE used in hospitals and other health care settings is critical in ensuring the safety of those on the frontline of COVID-19, but only if they are used properly.
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Image: comparison of chest x-ray images of healthy patients, patients with pneumonia and with COVID-19; Copyright: Asociación RUVID

AI: distinguishing pneumonia from COVID-19 from chest x-rays


A research team from Valencia's Polytechnic University (UPV), from the CVBLab, has developed a predictive artificial intelligence model that can tell the difference between healthy patients, those who are ill with pneumonia and those who have COVID-19, from chest x-rays.
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Image: Hand washing with running water and soap; Copyright: PantherMedia/artinun prekmoung

Hand Hygiene Day 2020


The Day of Hand Hygiene takes place annually on 5 May. Originally initiated by the World Health Organization (WHO), a reminder about hand hygiene could not be more appropriate at the current time. At the moment intensive hand washing with soap is an essential part in reducing the spread of infectious diseases like COVID-19.
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Image: woman in a protective suit working at the high-security laboratory; Copyright: IVI

Laboratory technology: coronavirus clone goes "viral"


Researchers in virology and veterinary bacteriology at the University of Bern have cloned the novel coronavirus (SARS-CoV-2). The synthetic clones are being used by research groups worldwide to test corona samples, find antiviral drugs and develop vaccines as quickly as possible. The method developed in Bern can also be used in future to combat other highly infectious viruses.
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Image: retina of a glaucoma patient; Copyright: UCL/Western Eye Hospital

AI-supported test for early signs of glaucoma progression


A new test can detect glaucoma progression 18 months earlier than the current gold standard method, according to results from a UCL-sponsored clinical trial. The technology, supported by an artificial intelligence (AI) algorithm, could help accelerate clinical trials, and eventually may be used in detection and diagnostics.
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Image: the researchers' H-cell setup used in developing their hydrogen peroxide production method; Copyright: Zheng Chen Lab

Green method to produce hydrogen peroxide in hospitals


A team of researchers has developed a portable, more environmentally friendly method to produce hydrogen peroxide. It could enable hospitals to make their own supply of the disinfectant on demand and at lower cost.
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Image: Person lying down with a man in white standing next to her in a medical setting; Copyright: Brennan Wesley/MUSC

AI could serve as backup to radiologists' eyes


"Everybody has a different trigger threshold for what they would call normal and what they would call disease," said U. Joseph Schoepf, M.D., director of cardiovascular imaging for MUSC Health and assistant dean for clinical research in the Medical University of South Carolina College of Medicine. And until recently, scans of damaged lungs have been a moot point, he said.
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Image: Preview picture of video

In the intensive care unit: Together against COVID-19


The coronavirus is pushing healthcare systems worldwide to their limits. The number of infections continues to rise – and with it the number of people who need intensive medical treatment and artificial respiration. However, the number of ventilators is limited. Solutions to support intensive care units are needed – quickly. We have taken a closer look at some of them.
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Image: A woman with a face mask is checking here smartphone with the word

COVID-19: tracing app warns of exposure while protecting privacy


Three Boston University computer scientists and engineers are working on a smartphone app that could let people know if they have come in contact with someone who has tested positive for COVID-19, while protecting the privacy of all parties.
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Image: Three scientists at a laboratory bench; Copyright: PantherMedia/AlexNazaruk

Superheroes in smocks: World Laboratory Day 2020


Laboratories and laboratory technology are perhaps the most important component of today's medicine - they save and secure quality of life, especially in times of infectious diseases such as COVID-19, but also in cases of cancer, chronic or other diseases. The World Laboratory Day on 04/23 draws attention to these superheroes of medicine.
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Image: A physician is using a disinfection dispenser; Copyright: PantherMedia/Robert Przybysz

WHO-recommended disinfectants effective against novel coronavirus


The formulations can be prepared quickly and easily by pharmacies and help alleviate the current shortage of disinfectants.
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Image: Smiling man is standing in nature with one had at his ear; Copyright:

In-ear sensors for monitoring vital parameters


Wearables offer practical solutions for the flexible measurement of data. The sensor from cosinuss° is worn directly in the ear and offers a precise monitoring of vital parameters.
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Image: A pile of transparent plastic boxes; Copyright: West Virginia University

COVID-19: intubation boxes help reduce risk to clinicians


A global pandemic, a worried wife and a campus that, like its home state, is full of connections, were the impetus for protective devices that were created at West Virginia University and are now being used by a variety of health care professionals at WVU Medicine J. W. Ruby Memorial Hospital.
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Image: 3D-printed swab; Copyright: UofL

3D-printed swabs fill gap in COVID-19 test kits


Innovation at the University of Louisville involving multiple departments at the university has led to a promising solution for the shortage of swabs in COVID-19 test kits. In response to a request from the Commonwealth of Kentucky, UofL's AMIST, along with faculty and students in the Schools of Dentistry, Engineering and Medicine have created a 3D printed swab made of a pliable resin material.
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Image: Health care personnel try on a prototype of the new face shield; Copyright: Gjøvik municipality

3D printed personal protection equipment for hospitals


NTNU in Gjøvik has developed a better design for face shields, which are part of the personal protection equipment used by medical professionals. Major production of the new shields – up to 250 per day – is starting on the university’s 3D printers this week.
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Image: scientist works on an ALS beamline; Copyright: Thor Swift/Berkeley Lab

Mobilizing x-ray to support COVID-19-related research


X-rays allow researchers to map out the 3D structure of proteins relevant to diseases at the scale of molecules and atoms, and Lawrence Berkeley National Laboratory's (Berkeley Lab's) Advanced Light Source (ALS) X-ray facility has been recalled to action to support research related to COVID-19, the coronavirus disease that has already infected about 2 million people around the world.
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Image: man with a laptop and facemask explains something to another man in a tent; Copyright: Robert Bosch Hospital/Christoph Schmidt

"Access checker" measures body temperature, heart and breathing rate


An innovative measurement method is helping to detect people infected with coronavirus from a safe distance. It detects fever, increased pulse rates and fast breathing without endangering the person conducting the testing. Fraunhofer IPA and Fraunhofer IAO are currently testing the procedure at the Robert Bosch Hospital in Stuttgart.
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Image: Conventional chest x-ray; Copyright: Toubibe/Pixabay

Coronavirus: new high-precision radiology system


Universidad Carlos III de Madrid (UC3M) is participating in a research project together with the Hospital General Universitario Gregorio Marañón (HGUGM), the Instituto de Investigación Sanitaria San Carlos and the company Sedecal Molecular Imaging (SMI), project coordinator, to develop a new high-precision radiology system for coronavirus pulmonary involvement.
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Image: Professor Andrew Brooks in the laboratory; Copyright: Rutgers University

Coronavirus: saliva test gets FDA approval


The FDA has granted emergency use authorization (EUA) to Rutgers' RUCDR Infinite Biologics and its collaborators for a new collection approach that utilizes saliva as the primary test biomaterial for the SARS-CoV-2 coronavirus, the first such approval granted by the federal agency.
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Image: tissue models in the laboratory; Copyright: K. Dobberke for Fraunhofer ISC

Coronavirus: tissue models for rapid drug testing


The pandemic caused by SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) is placing unprecedented restrictions on public life and economy. The global research efforts to fill the knowledge gaps regarding the new pathogen and to develop effective therapies are correspondingly large.
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Image: map shows spread of the coronavirus via tracking app; Copyright: PantherMedia / LZT (YAY Micro)

New COVID-19 tracking application launched by UC Davis


Researchers at the University of California, Davis, have developed a new web application that allows users to track COVID-19 cases and testing across the globe. The app offers a simple, intuitive way for users to track COVID-19 data at the country, state and county level.
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Image: doctor holds an lung imaging of a COVID-19 patient in her hands; Copyright: PantherMedia / Sobolovskyi

AI enables COVID-19 lung imaging analysis


With support from Amazon Web Services, health care providers are using AI in a clinical research study aimed at speeding the detection of pneumonia, a condition associated with severe COVID-19.
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Image: simple, low-cost ventilator; Copyright: Steven Norris / Georgia Tech

New ventilator based on resuscitation bags


A simple, low-cost ventilator based on the resuscitation bags carried in ambulances - and widely available in hospitals - has been designed by an international team of university researchers. The device, which is powered by a 12-volt motor, could help meet peak medical demands in the industrialized world and serve resource-constrained countries that don't have supplies of conventional ventilators.
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Image: woman infected by the corona virus; Copyright: PantherMedia / Wavebreakmedia (YAYMicro)

Virus-scanning tool detects previous COVID-19 infections


When a virus invades the body, it leaves fingerprints behind. A research tool known as VirScan can detect this evidence - from just a single drop of blood - and identify the viruses that have infected a person in the past. Soon, the new coronavirus will join the VirScan lineup.
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Image: Screenshot of the visualization tool for critical care bed capacities; Copyright: AG Data Analysis and Visualization / University of Konstanz

Visualization tool illustrates critical care bed capacities


A team of computer scientists from the University of Konstanz develops online platform for the registration and enquiry of free critical care beds all over Germany.
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Image: doctor attaches patient to ventilator; Copyright: PantherMedia / Wavebreakmedia (YAYMicro)

AI to predict corona-patients' risk of needing ventilators


As coronavirus patients are hospitalized, it is difficult for doctors to predict which of them will require intensive care and a respirator. Many different factors come into play, some yet to be fully understood by doctors.
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Image: UV Visual Lift; Copyright: by UVentions

Hygiene: Smart protection against pathogens like the coronavirus


Germs such as bacteria, viruses or pathogenic fungi can spread from one person to another through direct contact when we shake hands or touch objects. People touch door handles and push elevator buttons in public places and constantly move in and out of spaces. Regular manual high-level disinfection is practically impossible. UVentions GmbH has found an intelligent solution for this problem.
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