Blood-Brain Barrier Chip: in vivo-like drug and antibody transport -- MEDICA - World Forum for Medicine

Blood-Brain Barrier Chip: in vivo-like drug and antibody transport

17.06.2019

Image: microscope images of the human Blood-Brain Barrier-on-Chip; Copyright: Wyss Institute at Harvard University

Endothelial cells derived from induced human pluripotent stem cells in a development-inspired process, form a microvessel in the lower of two parallel microfluidic channels, while pericytes and astrocytes populating the upper channel connect to the microvessel across a dividing porous membrane.

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Image: Vials for blood samples; Copyright: Messe Düsseldorf