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Image: Schematic image of a complex molecule; Copyright: Thanh Truong

Design and test potential COVID-19 treatments from your phone

23/10/2020

You are invited to join the search for COVID-19 treatments--no lab coat or Ph.D. necessary: Anyone with a smartphone can download the app ViDok, which lets users pick from a library of molecules that might bind to key proteins on the SARS-CoV-2 virus, which causes COVID-19, and then can tweak the molecules to try to find a better fit.
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Image: A graphic showing an implant; Copyright: D. Chen et al., Science Translational Medicine (2020)

Tissue grafts of both bone and cartilage could regenerate a crucial jaw joint

23/10/2020

Scientists have engineered tissue grafts that, in pigs, regenerated both bone and cartilage in the temporomandibular joint (TMJ), a part of the jaw that can cause debilitating pain and disability when damaged.
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Image: Microscopic images of cells; Copyright: E. Rath/TUM

An alternative to animal experiments

22/10/2020

Researchers of the Technical University of Munich (TUM) have cultured so-called intestinal organoids from human intestinal tissue, which is a common byproduct when performing bowel surgery. These small “miniature intestines” can be used for molecular biological examinations and allow for a direct application of research results to humans, thereby making animal experiments redundant.
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Image: Computer-generated image showing round viruses with spikes; Copyright: PantherMedia/Sanda Stanca

Blood test could identify COVID-19 patients at risk of hyperinflammation

22/10/2020

A new study jointly led by Professor Tom Wilkinson and Dr Tristan Clark of the University of Southampton, has shown a blood test for five cytokines could help predict those at risk of life-threating overstimulation of immune defenses by COVID-19, and potentially tailor their treatment to tackle this.
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Image: A female researcher is sitting in front of a microscope in a laboratory; Copyright: Andreas Heddergott/TUM

Fighting corona with machine learning

21/10/2020

The Technical University of Munich (TUM) is starting five new research projects that focus on the coronavirus and the search for new active ingredients. For example, the use of algorithms could ensure a more precise classification of the illness in the future.
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Image: A female researcher is working at a device in a laboratory; Copyright: Chris Richards/University of Arizona

Funding to advance device for detecting COVID-19, cancer, contaminants

21/10/2020

In Judith Su's Little Sensor Lab, researchers are working to sense tiny amounts - down to a single molecule - of everything from doping agents to biomarkers for cancer, Alzheimer's disease, Lyme disease and, yes, even COVID-19.
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Image: A model of the human skull with a 3D printed implant in it; Copyright: PNAS

Bioceramic implant induces cranial regrowth

20/10/2020

A bioceramic implant has proved to stimulate regeneration of natural skull bone, so that even large cranial defects can be repaired in a way that has not been possible before. The research, led from the University of Gothenburg, is presented in the scientific journal PNAS.
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Image: Three female researchers are working in a laboratory; Copyright: John W. Braun Jr., USAMRIID VIO

Army researchers collaborate on universal antibody test for COVID-19

20/10/2020

Researchers with the U.S. Army Futures Command are part of a team that tested alternative ways to measure COVID-19 antibody levels, resulting in a process that is faster, easier and less expensive to use on a large scale. Their method holds promise for accurately identifying potential donors who have the best chance of helping infected patients through convalescent plasma therapy.
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Image: A round piece of metal from the 3D printer; Copyright: MUSC

3D metal printer expands possibilities for innovation

19/10/2020

When the Zucker Institute for Applied Neurosciences (ZIAN) at the Medical University of South Carolina needed to bring to life a neurosurgeon's idea for better instrumentation for sacroiliac surgery, there was one obvious partner to turn to: the MUSC College of Dental Medicine.
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Image: A man and a woman wearing protective clothing work in the laboratory; Copyright: University of Nevada, Reno

COVID-19 rapid test has successful lab results

19/10/2020

Rapid detection of the SARS-CoV-2 virus, in about 30 seconds following the test, has had successful preliminary results in Mano Misra's lab at the University of Nevada, Reno. The test uses a nanotube-based electrochemical biosensor, a similar technology that Misra has used in the past for detecting tuberculosis and colorectal cancer as well as detection of biomarkers for food safety.
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