In cooperation with Fresenius University of Applied Sciences in Idstein and the Technical University of Darmstadt, DiaSys has published an article in the journal Analytical and Bioanalytical Chemistry about the standardization of HbA1c. For many years, DiaSys enjoys a close cooperation with the University of Applied Science Fresenius in Idstein. Fresenius looks back on more than 160 years of scientific tradition from its foundation as a school of chemistry in 1848 – in fact, the founder Carl Remigius Fresenius is seen as the originator of food and diagnostic analytical sciences.
The published article describes the synthesis of two clinically relevant fructosamines Fru-Val and Fru-Val-His via a protected glucosone intermediate, which is a new, fast and efficient protocol for the synthesis and purification of fructosamines in suitable yield and purity.
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