Ohno and colleagues' prospective study included 98 patients (64 men, 34 women; median age, 74 years) with SCLC who underwent conventional staging tests (brain MRI; neck, chest, and abdominopelvic CT; bone scintigraphy), FDG PET/CT, and FDG PET/MRI within 2 weeks before treatment. After MRI technologists performed coregistration via proprietary software (Canon Medical Systems), two nuclear medicine physicians and two chest radiologists independently reviewed the examinations in separate sessions.
In patients with SCLC, accuracy for T category was higher (p<.05) for whole-body MRI (94.9 percent) and FDG PET/MRI (94.9 percent) than for FDG PET/CT (85.7 percent). Meanwhile, TNM stage accuracy was higher (p<.05) for whole-body MRI (88.8 percent) and FDG PET/MRI (86.7 percent) than for FDG PET/CT (77.6 percent) and conventional staging tests (72.4 percent).
"These additional observations may relate to a superior role of MRI in assessing the extent of local soft tissue invasion by tumor, as has been observed in settings other than SCLC," added the authors of this AJR article.
MEDICA-tradefair.com; Source: American Roentgen Ray Society