BlueWell Liver Screen is the first ELISA test able to detect the most relevant AIH (autoimmune hepatitis) autoantibodies in one single well.
The microwells are coated with a mixture of highly purified antigens:
. LKM-1 and LC-1 are human, full-length recombinant proteins produced in an eukaryotic expression system which ensures native folding and unrestricted immunological reactivity of the antigens.
. SLA is purified by affinity chromatography, using human anti-SLA antibodies, from rat liver extract.
. F-actin is prepared by in vitro polymerisation of highly purified actin monomers from rabbit skeletal muscle. After polymerisation the actin filaments (F-actin) are submitted to a specific folding/stabilizing process ensuring full antigenicity.
The kit includes ready-to-use reagents and controls (Positive, Negative and Cut-Off). The test procedure is completed in less than 90 minutes.