Background Reports 2019 -- MEDICA - World Forum for Medicine

Image: Scientist works with medical test tube to analyze green liquid; Copyright: DC_Studio

DC_Studio

Diagnosing breast cancer through liquid biopsy

22/09/2022

Breast cancer diagnosis usually includes invasive testing with tissue biopsies. The samples have to be extracted from the cancerous tissue or cells. To make the process easier on the patients, the project LIBIMEDOTS is currently developing a different approach with liquid biopsy technology.
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Image: A woman in a blue blazer, senior author Dr. Deb Schrag, poses for the camera; Copyright: European Society for Medical Oncology

European Society for Medical Oncology

New era of early cancer detection with blood test

14/09/2022

New data supporting the accuracy of multi-cancer early detection (MCED) blood testing, have major implications for future cancer care provision.
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Image: Microscope in biotechnology laboratory with laboratory samples in the background; Copyright: ckstockphoto

ckstockphoto

Machine learning to unlock genomic code in clinical cancer samples

13/09/2022

A new paper from University of Helsinki, published in Nature Communications, suggests a method for accurately analysing genomics data in cancer archival biopsies.
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Image: Close-up of doctor takes blood on analysis; Copyright: Satura_

Satura_

Blood test detects Alzheimer’s in people with Down syndrome

02/09/2022

Around 80% of people with Down syndrome develop Alzheimer’s disease, often when they are between 40 and 50 years old. A study led by Lund University in Sweden has shown that a simple blood test can detect Alzheimer’s disease in people with Down syndrome with a high degree of certainty.
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Image: Two smiling men are standing in front of a large, box-shaped device with a glass front – Prof. Niels Voigt, Dr. Thomas Mager; Copyright: mbexc

Many paths are open to neurons born early

23/08/2022

When it comes to royalty, things are clear: The monarch's first child inherits the crown. Siblings born later must make do with a less glamorous profession. This is quite similar for some nerve cells in the brain. In their case, it is the time of their emergence that determines their further career. This is shown by a recent study by the University of Bonn.
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Image: Scientist pipettes a DNA sample into a tube; Copyright: westend61

westend61

Cancers and heart disease could be diagnosed more easily with new rapid test

12/08/2022

Imperial researchers have built a new easy-to-use test that could diagnose non-infectious diseases like heart attacks and cancers more quickly.
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Image: Two smiling men sitting in an inner courtyard - Klaus Gerwert and Léon Beyer; Copyright: RUB/Marquard

RUB/Marquard

Sensor: early Alzheimer’s detection up to 17 years in advance

01/08/2022

The dementia disorder Alzheimer’s disease has a symptom-free course of 15 to 20 years before the first clinical symptoms emerge. Using an immuno-infrared sensor developed in Bochum, a research team is able to identify signs of Alzheimer’s disease in the blood up to 17 years before the first clinical symptoms appear.
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Image: Micrograph of drying patterns of peptide solutions; Copyright: Karlsruhe Institute of Technology

Karlsruhe Institute of Technology

Peptide "fingerprint" enables earlier diagnosis of alzheimer’s disease

28/07/2022

Neurodegenerative diseases like Alzheimer’s disease or Parkinson’s disease are caused by folding errors (misfolding) in proteins or peptides, i.e. by changes in their spatial structure.
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Image: A person measures the glucose level using an app; Copyright: microgen

microgen

'Smart necklace' biosensor may track health status through sweat

28/07/2022

Researchers have successfully tested a device that may one day use the chemical biomarkers in sweat to detect changes in a person’s health.
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Image: Woman collecting blood samples for testing on different diseases; Copyright: Prostock-studio

Prostock-studio

Biomarkers: Early detection of Tuberculosis in people with HIV

26/07/2022

Findings of the LMU University Hospital Munich, the German Center for Infection Research (DZIF) and the U.S. Military HIV Research Program in collaboration with the African Cohort Study (AFRICOS) Group suggest that blood-based biomarkers can often detect incipient Tuberculosis (TB) between six to twelve months earlier in people living with HIV before a sputum-based TB diagnosis is possible.
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Image: Researchers work in a laboratory with a microscope and a laptop; Copyright: ckstockphoto

ckstockphoto

How to find marker genes in cell clusters

08/07/2022

New method facilitates identification of cell-type specific genes in single-cell data: The thousands of cells in a biological sample are all different and can be analyzed individually, cell by cell.
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Image: A doctor performs an ultrasound diagnosis on a patient; Copyright: Natabuena

Natabuena

Kiel assistant physician awarded Else Kröner Memorial Fellowship

07/07/2022

In the funded project, Dr. Florian Tran, clinician scientist at the Cluster of Excellence PMI, plans to use a new technology to detect individual signatures in intestinal tissue.
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Image: Visualization of a miRNA expression using DNA computing and nanopore decoding; Copyright: Tokyo University of Agriculture and Technology

Tokyo University of Agriculture and Technology

Detection of cancer biomarkers using nanopore-based DNA computing technology

05/07/2022

Cholangiocarcinoma, also known as bile duct cancer, is a cancer type with a characteristically high mortality. At the time of diagnosis, most bile duct cancers are typically already incurable. This is why methods for the early diagnosis of bile duct cancer are urgently needed.
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Image: Yujin Hoshida poses for the camera; Copyright: UT Southwestern Medical Center

UT Southwestern Medical Center

Blood test to predict liver cancer risk

04/07/2022

Protein levels in blood samples of patients with nonalcoholic fatty liver disease reveal those at highest risk who should be screened regularly for liver cancer.
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Image: A laboratory worker performs a blood test; Copyright: seventyfourimages

seventyfourimages

Dementia: Blood levels could point to early loss of neuronal connections

01/07/2022

Researchers from DZNE and Ulm University Hospital have identified a protein in the blood that may indicate the degradation of neural connections years before the onset of dementia symptoms.
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Image: Blut sample in a test tube; Copyright: gpointstudio

gpointstudio

New blood biomarker identified for status of fatty liver disease

29/06/2022

A MedUni Vienna study team has identified the role of a specific subtype of macrophages (white blood cells) in progressive non-alcoholic fatty liver disease.
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Image: Doctor checks an elderly gentleman's eye health with a beam of light; Copyright: twenty20photos

twenty20photos

New hope for a therapy against retinitis pigmentosa

27/06/2022

Retinitis pigmentosa, a degenerative genetic disease of the eye, is characterized by progressive vision loss, usually leading to blindness.
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Image: Blood sample labelled

panthermedia.net/olanstock

Cardiac diagnostics – prompt and personalized

08/11/2019

If physicians suspect an acute myocardial infarction, they first order an ECG. This test is very established and allows cardiologists to quickly diagnose acute heart attacks – though the test does not detect less common heart attack symptoms. So far, those patients had to wait up to twelve hours before a heart attack could be accurately diagnosed or ruled out. But things are about the change.
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