He explained that the researchers tested the properties of a range of titanium implant coatings, differing in composition, thickness, and structure. The coatings were applied by atomic layer deposition (ALD) in special vacuum equipment. After the modification of the implants, the successful studies were carried out on cells in vitro, and then in vivo on experimental animals.
"Currently we started applying silver nanoparticles on the surface of titanium since this chemical element obtains useful antibacterial properties and should reduce the risk of implant rejection. However, to use the silver coatings freely, it is necessary to adjust the conditions and the general method of obtaining the material," said Dr. Nazarov of the Research Park, St. Petersburg State University.
According to the scientists, an important part of the study is to select the size and morphology of nanoparticles thus not causing toxic effects of silver on living cells and at the same time preserving the beneficial properties of the previously developed coating.
MEDICA-tradefair.com; Source: Peter the Great Saint-Petersburg Polytechnic University