When less is more: Approach for low-cell-number epigenomic profiling -- MEDICA - World Forum for Medicine

When less is more: Approach for low-cell-number epigenomic profiling

12/14/2018

Image: Schematic model of ChIL reaction; Copyright: Yuko Sato (Tokyo Institute of Technology)

This is a schematic model of ChIL reaction. The oligonucleotide conjugated with the second-ary antibody (green), which binds to the primary antibody (blue) recognizing a spe-cific medication of histone (purple), is integrated into proximal genomic DNA by Tn5 transposase (brown).