The new invention by Dr. Jason Heikenfeld provides chronological assurance of sweat analyte data.
Sweating can contribute to non-invasive drug monitoring. The new sensor helps with the analysis.
Eccrine Systems, Inc., an advanced sweat sensor company, today announced that a key patent, US10136831, has been issued to Dr. Jason Heikenfeld, Co-Founder & CSO, and prominent University of Cincinnati researcher. The company holds exclusive rights to the UC patent.
he patented invention covers the use of on-body sweat devices that are capable of electronically correlating two or more measurements of an analyte with the time at which the analyte emerged in newly excreted sweat. Without the use of the invention it is likely not possible to correlate sweat analyte data trends with chronological blood values or similar physiological measurements. Heikenfeld developed his invention over four years ago at a time when continuous on-body measurement of sweat analytes was at its inception. Heikenfeld is a well-known scientific leader of the wearable sweat sensor space with many of its most prescient and important advances to his credit.
The company uses Heikenfeld's invention to time correlate the data derived from its sweat sensor devices, including data and algorithms that will define the pharmacokinetic (PK) profile of medications that are excreted in locally stimulated sweat. "Non-invasive medication monitoring is a great example of the utility of Jason's invention," says Dr. Gavi Begtrup, CEO of Eccrine Systems. "You can't devise an on-body device to derive a sweat pharmacokinetic curve, and then correlate that curve to a drug's blood PK curve, without using this invention. This is a big deal given the estimated $500 billion dollar annual healthcare cost of non-optimized medication therapy, a significant portion of which can result from individual PK differences that cause failed treatment outcomes."