Tumor markers: State-of-the-art diagnostics for personalized medicine -- MEDICA - World Forum for Medicine

Tumor markers: State-of-the-art diagnostics for personalized medicine

When cancer is diagnosed, the terms tumor markers or biomarkers keep popping up. They describe characteristics that are not found in healthy persons. The classic tumor markers can be easily detected in blood samples or other body fluids. Other analysis methods require more effort. Yet they all share one thing in common: biomarkers indicate a potential tumor.


Photo: Hand takes a blood pipe

Tumor markers are measurable substances in the blood that may occur in increased concentrations. They are formed by the cancer cells themselves, or by the body in response to the cancer; © panthermedia.net/ angellodeco

Photo: histopathologic shot of a kidney

Tissue-based prognostic tumor markers: Immunohistochemical staining of DcR3 protein in kidney carcinoma (brown: DcR3 protein expression; blue: tumor cell nucleus). Tumors with high expression of DcR3 behave more aggressively than DcR3 negative tumors;& copy; Prof. Wilfried Roth

Photo: Woman working in the lab in front of an extractor

There are more than 30 different urine biomarker, which are used for the diagnosis of bladder cancer. However, few of these markers are commercially available. The remaining markers are often still in the testing phase;© panthermedia.net/matej kastelic

Photo: Melanie Günther; Copyright: B. Frommann

©B. Frommann