Process to Improve Storage Stability of Probiotics -- MEDICA Trade Fair

Image: A healthy liver cell and a HCV-infected liver cell in comparison; Copyright: Marianne Doré Hansen & Marit Anthonsen

How hepatitis C hides in the body

17/10/2017

The Hepatitis C (HCV) virus is a sly enemy to have in one’s body. Not only does it manage to make itself invisible to the immune system by breaking down communication between the immune cells, it also builds secret virus "factories" that quickly go into mass production.
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mHealth: how mobile choices can successfully reach users

02/10/2017

mHealth has been slated to revolutionize the healthcare market for the past few years. Yet things are not quite as easy for apps and wearables as it may seem. A recently conducted study reveals that there are still many obstacles to overcome before manufacturers and health professionals can connect with patients and their mobile devices.
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Why only half of healthcare workers have the flu vaccine

20/09/2017

The low uptake of flu vaccination among medical students and doctors is influenced by social attitudes say researchers. Despite a recommendation from the Chief Medical Officer for England that all healthcare workers are vaccinated annually, only 55 percent are protected against the spread of influenza, this could contribute to staff sickness and mortality among elderly patients.
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Image: illustration of the human immune system; Copyright: panthermedia.net/ralwel

Immune cells help fat deal with environmental challenges

20/09/2017

Immunosuppressive regulatory T-cells play an important role in the functioning of adipose tissue. This is the discovery of scientists from the Helmholtz Diabetes Center (HDC) at Helmholtz Zentrum München and the Technical University of Munich (TUM). Their findings are published in the journal 'Cell Metabolism'.
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A hair-trigger for cells fighting infection

19/09/2017

To fight infections cells in the immune system play a dangerous game with their own genes. Damaging genes allows B cells to make antibodies that are specifically equipped to target to specific causes of illness, but damaging genes also puts them at risk of becoming cancerous.
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Thorough analysis reveals immune system dynamics after immunotherapy

13/09/2017

By combining new system-biological analyses and advanced data analysis, researchers at Karolinska Institutet have been able to monitor the maturation process of the immune system of leukaemia patients who have undergone stem cell transplantation.
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New receptor found on scavenger cells

08/09/2017

Adenoviral infections have a mild disease progression in healthy people, but it can be dangerous for immunocompromised people. If a patient is infected with the virus and gets a bacterial infection on top of it, it can lead to an excessive inflammatory response known as a cytokine storm, an overreaction by the immune system leading to high concentrations of proteins that promote inflammation.
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Treating arthritis with algae

06/09/2017

Researchers at ETH Zurich, Empa and the Norwegian research institute SINTEF are pursuing a new approach to treating arthritis. This is based on a polysaccharide, a long-chain sugar molecule, originating from brown algae.
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Chronic stress induces fatal organ dysfunctions via a new neural circuit

04/09/2017

New research reveals the mechanisms behind the effects of chronic stress and tiny inflammations in the brain on fatal gut failure. Hokkaido University researchers revealed that fatal gut failure in a multiple sclerosis (MS) mouse model, EAE, under chronic stress is caused by a newly discovered nerve pathway.
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Image: Collage of several MRI images of the heart, in which different locations are marked with red arrows; Copyright: University Hospital Münster/Ali Yilmaz

Myocarditis: more specific diagnosis thanks to molecular imaging

01/09/2017

There are many causes of myocarditis or inflammation of the heart muscle. Oftentimes, the culprits are viruses or bacteria and sometimes even an acute heart attack. Regardless of the cause, it creates a challenge for cardiologists: a diagnosis tends to be only nonspecific without a biopsy. A cardiac MRI and molecular imaging promise to provide assistance.
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DNA sensor plays critical role in cancer immunotherapy via response to unexpected DNA form

31/08/2017

UT Southwestern Medical Center researchers report for the first time that tumors stressed by cancer immunotherapy release their mitochondrial DNA into nearby immune cells, triggering a host alert system.
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New insights into the world of trypanosomes

29/08/2017

Such detailed images of the pathogen that causes sleeping sickness inside a host are unique so far: They illustrate the manifold ways in which the parasites move inside a tsetse fly. A research team from the University of Würzburg's Biocenter has presented the images.
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Understanding how omega-3 dampens inflammatory reactions

29/08/2017

Omega-3 fatty acids, which we primarily get through eating fatty fish, have long been thought to be good for our health. Many dietary studies have suggested that high intake is associated with a reduced risk of various disorders. Clinical trials have also shown beneficial anti-inflammatory effects in patients taking omega-3 supplements.
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Image: illustration of the immune system; Copyright: panthermedia.net/ralwel

New test for rare immunodeficiency

23/08/2017

Researchers at the University of Basel have developed a test to quickly and reliably diagnose a rare and severe immune defect, hepatic veno-occlusive disease with immunodeficiency. They reported on their findings in the "Journal of Clinical Immunology".
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Immune system can be modulated by targeted manipulation of cell metabolism

22/08/2017

In its attempt to fight a serious bacterial infection, caused by listeria, for example, the immune system can become so over-activated that the resulting inflammatory response and its consequences can quickly lead to death.
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Genetic variants found to play key role in human immune system

17/08/2017

Genetic differences in immune response demonstrate interaction of genetics and environment linked to disease risk.
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One step closer in explaining MS relapse during upper respiratory infection

17/08/2017

For most of us, the flu is just the flu. We suffer through it for several days, and eventually bounce back. But for patients with multiple sclerosis (MS) and other neurological diseases, the flu can trigger a cascade of immune responses that result in a full-blown relapse of the disease.
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Image: chalk board with sketch of sugar molecule formula; Copyright: panthermedia.net/Boris Zerwann

Cancer detection with sugar molecules

16/08/2017

Scientists from the University of Würzburg have synthesized a complex sugar molecule which specifically binds to the tumor protein Galectin-1. This could help to recognize tumors at an early stage and to combat them in a targeted manner
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New ultrafast method for determining antibiotic resistance

15/08/2017

Researchers at Uppsala University have developed a new method for very rapidly determining whether infection-causing bacteria are resistant or susceptible to antibiotics. The findings have now been published in the US journal Proceedings of the National Academy of Sciences (PNAS).
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In the test tube instead of under the knife

04/08/2017

Freiburg neuroscientists develop new forms of diagnosis and therapy for temporal lobe epilepsy.
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Immune system may mount an attack in Parkinson's disease

04/08/2017

A new study suggests that T cells, which help the body's immune system recognize friend from foe, may play an important role in Parkinson's disease (PD). The study, published in the journal Nature, was supported by the National Institute of Neurological Disorders and Stroke (NINDS), part of the National Institutes of Health.
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Image: Malaria mosquito; Copyright: panthermedia.net/Michael Pettigrew

Malaria already endemic in the Mediterranean by the Roman period

03/08/2017

Malaria was already widespread on Sardinia by the Roman period, long before the Middle Ages, as indicated by research at the Institute of Evolutionary Medicine of the University of Zurich with the help of a Roman who died 2,000 years ago.
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Do we need separate his and hers medicine cabinets?

03/08/2017

Perhaps you have come across the titles "Men are from Mars, women are from Venus" or "Why men don’t listen and women can’t read maps": just two of the many books and articles – some enlightening or amusing and others irritating – that theorise about fundamental differences between men and women.
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Image: A nurse is putting a patch on a patient's upper arm; Copyright: panthermedia.net/Peter Jobst

Skin vaccination with microneedle patch, influenza fusion protein

27/07/2017

A boosting skin vaccination with a biodegradable microneedle patch and protein constructed from sequences of influenza virus subtypes could improve the effectiveness of conventional influenza vaccines, according to a study led by Georgia State University.
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Image: A petri dish with yellow bacterial cultures on a black ground; Copyright: panthermedia.net/kwanchaichaiudom

Laboratory medicine: confronting infections with speed and foresight

03/04/2017

The laboratory is one of the most important and pivotal bastions in patient care. In the laboratory, acute, chronic and genetic diseases are diagnosed, the progression of diseases such as diabetes is regularly checked or specialists look for biomarkers to adapt cancer therapies.
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Diabetes: comprehensive prevention, early "vaccination"?

08/04/2016

A diagnosis of diabetes often catches new patients off guard - for instance if they end up in the emergency room suffering from metabolic decompensation. Children are often affected by this. Their immune system destroys the insulin-producing cells in the pancreas early on in their lives, thus causing type 1 diabetes.
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Cancer Immunotherapy: Individual mutations as new target structures

01/06/2015

A tumor is as unique as the person who is affected by it. For a long time, it was assumed this would make treatment more difficult since cancer drugs are not able to be one hundred percent effective in targeting the affected cells. In this interview with MEDICA.de, Professor Ugur Sahin explains why it is precisely these individual mutations that make him hopeful for a new type of therapy.
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Vaccines: activatable depot to replace multiple injections

22/08/2014

Besides antibiotics, vaccines may be the most important development in medicine: they protect us from diseases by “introducing” our immune system to pathogens. This way, a small injection saves us from severe and potentially mortal courses of disease.
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Multi-resistant bacteria want to conquer the world

01/08/2014

Bacteria lurk everywhere: on the skin, in the intestines and in every puddle. Most of them that are hanging out in the human body are good bacteria. But not all of them. Those pathogens that exhibit resistance and are thus very hard to combat are the most dangerous kind. Their spread threatens people all over the world.
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"The immunosensory system goes beyond the actual immune cells"

22/01/2014

It guards the body but can become its enemy: the immune system defends us from intruding pathogens; it is also able to cause severe diseases if it falsely recognizes the body itself as a threat. Molecular receptors in the whole body enable the immune system to “sense” what happens within.
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