Surgeon Charles J. Yeo, M.D., Samuel D. chair of surgery at Jefferson Medical College of Thomas Jefferson University, and his colleagues studied records of pancreatic surgery during the last 35 years at Johns Hopkins University and found that contrary to what many both in and out of medicine may believe, major pancreatic cancer surgery can successfully be performed on patients in their 80s, 90s and even older.
In the study, reported recently in the Journal of Gastrointestinal Surgery, Dr. Yeo and co-workers examined records of nearly 2,700 cases of the standard Whipple operation for pancreatic disease, including cancer. Of these, about 1,000 operations were performed in the last four years. Of this group, 207 patients were 80 years old or older. Those who were 80 to 89 years of age had a mortality rate of 4.1 percent (8 of 197), and a complication rate of 52.8 percent.
Those younger than 80 years old had a mortality rate of 1.7 percent, with a complication rate of 41.6 percent. Of 10 patients 90 or older, the researchers reported no deaths after surgery, though half had complications. Of those 80 to 89 years old, 59.1 percent lived for at least one year, while 60 percent of patients 90 years and older lived that long after surgery.
Such complication rates for individuals at least 80 years old are what would be expected, Dr. Yeo says, and involve conditions that afflict many that age, such as heart disease, diabetes and high blood pressure. “The general aging population isn’t dying from pancreas disease,” he notes. “They are dying from other causes.”
The five-year survival of those who were operated on for cancer is comparable to the general population, he says. “In the general population, five-year survival in healthy individuals at age 80 is 69 percent. In our study, it was 55 percent, which isn’t that much different.”
MEDICA.de; Source: Thomas Jefferson University Hospital