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How new blood vessels sprout
IBS biologists discovered a key regulator of normal as well as pathological formation of new blood vessels.
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From bed to bench and back to bed: Mimicking how HPV-positive cancer responds to treatment
Patients with head and neck squamous cell carcinoma who are positive for human papilloma virus (HPV-positive) have been observed to respond significantly better to chemo-radiotherapy than HPV-negative patients. This observation is surprising because HPV infection leads to an increased risk of developing oropharyngeal cancer. To date, the reason for this dichotomy has not been well understood.
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New receptor found on scavenger cells
Adenoviral infections have a mild disease progression in healthy people, but it can be dangerous for immunocompromised people. If a patient is infected with the virus and gets a bacterial infection on top of it, it can lead to an excessive inflammatory response known as a cytokine storm, an overreaction by the immune system leading to high concentrations of proteins that promote inflammation.
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Altered bacterial communities in the gut could be an indicator for Parkinson’s disease
Parkinson's disease is an insidious disease: by the time it manifests as the typical motor dysfunctions such as tremors or muscle rigidity, portions of the brain have already been irreversibly destroyed. By this stage, the disease will have often begun already decades earlier.
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New understanding of how muscles work
Muscle malfunctions may be as simple as a slight strain after exercise or as serious as heart failure and muscular dystrophy. A new technique developed at McGill now makes it possible to look much more closely at how sarcomeres, the basic building blocks within all skeletal and cardiac muscles, work together. It's a discovery that should advance research into a wide range of muscle malfunctions.
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New drug targets for a rare kidney and liver disease
In a joint international study, researchers from Osaka University have partnered with research groups from the United States and Spain to uncover how mutations in a single gene called PKHD1 lead to symptoms associated with a rare kidney and liver disease, ARPKD (autosomal recessive polycystic kidney disease).
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Treating arthritis with algae
Researchers at ETH Zurich, Empa and the Norwegian research institute SINTEF are pursuing a new approach to treating arthritis. This is based on a polysaccharide, a long-chain sugar molecule, originating from brown algae.
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Recurrence of prostate cancer could be reduced thanks to exciting new discovery
Ground breaking research could reduce the recurrence of prostate cancer in males, a new study in the journal Nature Communications reports.
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Gut microbes may talk to the brain through cortisol
Gut microbes have been in the news a lot lately. Recent studies show they can influence human health, behavior, and certain neurological disorders, such as autism. But just how do they communicate with the brain?
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Mayo Clinic researchers review the clinical potential of senolytic drugs on aging
Researchers are moving closer to realizing the clinical potential of drugs that have previously been shown to support healthy aging in animals.
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